Publication date: Available online 14 September 2018Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Roghiyeh Faridnia, Ahmad Daryani, Shahabeddin Sarvi, Mehdi Sharif, Hamed KalaniAbstractToxoplasma gondii is an obligate intracellular parasitic protozoan that infects a wide variety of vertebrates as intermediate hosts. The aim of the current systematic review study is to clarify the latest status of studies in the literature regarding rhoptry-associated recombinant proteins or rhoptry-associated recombinant DNAs as potential vaccines against toxoplasmosis. The search was performed systematically in 8 databases, four in English and four in Persian, up to February 2017. Overall, ROP2 was the most commonly used ROPs in DNA vaccines (27.27%) and protein vaccines (...
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