Studying the result of underlay myringoplasty using platelet-rich plasma.

Studying the result of underlay myringoplasty using platelet-rich plasma.

J Laryngol Otol. 2018 Oct 29;:1-5

Authors: Yadav SPS, Malik JS, Malik P, Sehgal PK, Gulia JS, Ranga RK

Abstract
OBJECTIVE: Perforations of the tympanic membrane are treated with various surgical techniques and materials. This study aimed to determine the efficacy of platelet-rich plasma during underlay myringoplasty.
METHODS: The study included 40 patients. Autologous platelet-rich plasma was applied in-between temporalis fascia graft and tympanic membrane remnant during underlay myringoplasty in group 1 (n = 20). The outcome was evaluated after three months and compared with group 2 (n = 20), a control group that underwent routine underlay tympanoplasty.
RESULTS: After three months' follow up, graft uptake was 95 per cent in group 1 and 85 per cent in group 2 (p < 0.03). Mean hearing threshold gain was 18.62 dB in group 1 and 13.15 dB in group 2. This difference was statistically significant (p < 0.01).
CONCLUSION: Platelet-rich plasma, with its ease of preparation technique, availability, low cost, autologous nature and good graft uptake rate, justifies its use in tympanoplasty type I procedures.

PMID: 30370872 [PubMed - as supplied by publisher]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OeLEsQ