Publication date: Available online 7 September 2018Source: Fish & Shellfish ImmunologyAuthor(s): Nan Chen, Jingjing Jiang, Xiaojian Gao, Xixi Li, Yue Zhang, Xiaodan Liu, Hui Yang, Xuwen Bing, Xiaojun ZhangAbstractHemorrhagic septicemia of mandarin fish (Siniperca chuatsi) was mainly caused by Aeromonas hydrophila which was an opportunistic pathogen. In recent years, the disease has caused tremendous economic loss with high morbidity and mass mortality in the mandarin fish breeding industry. Histopathological analysis and the immune related gene expression profiles of mandarin fish (S. chuatsi) infected with A. hydrophila were investigated in this study. Transmission electron microscopy (TEM) images showed that the cells of A. hydrophila densely covered with a mass of fimbriae. Histopatholo...
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