Increased inflammatory responsiveness of peripheral blood mononuclear cells (PBMCs) to in vitro NOD2 ligand stimulation in patients with ankylosing spondylitis.

CONCLUSIONS: This study indicated that AS PBMCs were hyper-responsive to MDP stimulation. This observation implies an important role of NOD2 in the pathogenesis of inflammatory diseases including AS. PMID: 30265175 [PubMed - as supplied by publisher] (Source: Immunopharmacology and Immunotoxicology)

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