Imatinib stimulates PGE2 and attenuates cytokine release via EP4 receptor activation

Imatinib increases PGE2 levels which leads to an EP4-dependent reduction in cytokine release. These effects can also be observed in imatinib-treated patients at therapeutic doses, highlighting its potential as an anti-inflammatory agent.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OoMRma