Ralstonia eutropha, containing high poly-β-hydroxybutyrate levels, regulates the immune response in mussel larvae challenged with Vibrio coralliilyticus

Publication date: January 2019Source: Fish & Shellfish Immunology, Volume 84Author(s): Nguyen Van Hung, Peter De Schryver, Nguyen Viet Dung, Nancy Nevejan, Peter BossierAbstractMarine invertebrates rely mainly on innate immune mechanisms that include both humoral and cellular responses. Antimicrobial peptides (AMPs), lysozyme and phenoloxidase activity, are important components of the innate immune defense system in marine invertebrates. They provide an immediate and rapid response to invading microorganisms. The impact of amorphous poly-β-hydroxybutyrate (PHB-A) (1 mg PHB-A L−1) on gene expression of the AMPs mytimycin, mytilinB, defensin and the hydrolytic enzyme lysozyme in infected blue mussel larvae was investigated during "in vivo" challenge tests with Vibrio coralliilyticus...

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