New DiaP277 analogue shifts DCs to tolerogenic, and modulates NF-K β1 to suppress autoreactive T lymphocytes in the type 1 diabetic mice.

In conclusion, VP showed promising immune potential to modulate immune regulatory responses and shifts DCs to suppress autoreactive Th1 cells which ameliorated immunosuppressive potency in the type1 diabetic mice. PMID: 30382756 [PubMed - as supplied by publisher] (Source: Autoimmunity)

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