Preoperative management of spontaneous cerebrospinal fluid rhinorrhea with acetazolamide

ConclusionThis is the first study to report the use of acetazolamide therapy as a primary treatment option for spontaneous CSF rhinorrhea. This therapy enabled surgery to be avoided in 31.3% of patients. This would indicate that in the absence of other contraindications for delaying repair, a trial of acetazolamide therapy could be considered as an initial option in the management of isolated spontaneous CSF rhinorrhea. (Source: International Forum of Allergy and Rhinology)

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