IFN-γ and CD25 drive distinct pathological features during hemophagocytic lymphohistiocytosis

Studying the pathogenesis of hemophagocytic lymphohistiocyosis, we found a striking dichotomy between the hematological and inflammatory components of HLH. Hematological features are strictly dependent of IFN-γ, while inflammation is driven by dysregulated IL-2 signaling.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BrhbTU