STAT1 gain-of-function compromises skin host defense in the context of interferon-γ signaling

Gain-of-function mutations in STAT1 cause epidermal host defense deficiency in a Th1 context thereby contributing to chronic mucocutaneous candidiasis.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QBkUsx