< b > < i > Dermatophagoides farinae < /i > < /b > Upregulates the Effector Functions of Eosinophils through αMβ < sub > 2 < /sub > -Integrin and Protease-Activated Receptor-2

Conclusions: These findings suggested that Df extract and Der f 1 directly activate eosinophil functions through αMβ2-integrin and PAR-2. Eosinophil activation by HDM may play roles in the aggravation of allergic symptoms, not only in HDM-sensitized patients, but also in nonsensitized patients.Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)

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