Omalizumab effectiveness in asthma-COPD overlap: Post hoc analysis of PROSPERO

Asthma and chronic obstructive pulmonary disease (COPD) overlap (ACO), defined as the coexistence of clinical features of asthma and COPD, is common.1,2 Although ACO is heterogeneous, common subphenotypes of ACO include those with asthma who are older than 40  years with a history of smoking and/or those who have persistent, progressive, and partially reversible airflow limitation.2 (Source: Journal of Allergy and Clinical Immunology)

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