Nonlesional Atopic Dermatitis Skin Shows Alterations in Langerhans Cells in Close Proximity to Tight Junction Fragmentation

Disruption of epidermal tight junctions (TJs), is thought to promote immunological responses to epicutaneous antigens. The Atopic Dermatitis Research Network performed a cross-sectional study to visualize TJs and Langerhans cells (LCs) in the skin of atopic dermatitis (AD) and nonatopic (NA) controls. (Source: Journal of Allergy and Clinical Immunology)

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