| Global Anaplastic Thyroid Cancer Drug Market 2018- Genelux Corporation, Immune Pharmaceuticals Inc., Millennium ... Browse Live News (press release) (blog)Full coverage |
| Timely care key to improving survival rates and racial disparities Medical XpressFull coverage |
| Global Anaplastic Thyroid Cancer Drug Market 2018- Genelux Corporation, Immune Pharmaceuticals Inc., Millennium ... Browse Live News (press release) (blog)Full coverage |
| Timely care key to improving survival rates and racial disparities Medical XpressFull coverage |
| Global Anaplastic Thyroid Cancer Drug Market 2018- Genelux Corporation, Immune Pharmaceuticals Inc., Millennium ... Browse Live News (press release) (blog)Full coverage |
| Global Anaplastic Thyroid Cancer Drug Market 2018- Genelux Corporation, Immune Pharmaceuticals Inc., Millennium ... Browse Live News (press release) (blog)Full coverage |
Peter Bannas, Friedrich Koch-Nolte (Source: Frontiers in Immunology)
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Chelsea L. Edwards, Marcela Montes de Oca, Fabian de Labastida Rivera, Rajiv Kumar, Susanna S. Ng, Yulin Wang, Fiona H. Amante, Kohei Kometani, Tomohiro Kurosaki, Tom Sidwell, Axel Kallies, Christian R. Engwerda (Source: Frontiers in Immunology)
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ConclusionAnalysis of available evidence shows moderate certainty that the use of probiotics can relieve symptoms of children with cow 's milk allergy. The reduction in certainty is due to imprecise results. Moreover, there is low certainty that probiotics can induce tolerance among children with cow's milk allergy, due to problems of imprecision and attrition bias. In the subgroup analysis,Lactobacillus rhamnosus GG administration likely results in inducing tolerance among infants with suspected cow 's milk allergy. Only studies on CMA were analyzed since no studies were found on probiotics as treatment for other types of food allergy among children. (Source: World Allergy Organization Journal)
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Istv án Vadász, Rudolf Lucas (Source: Frontiers in Immunology)
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Peter Bannas, Friedrich Koch-Nolte (Source: Frontiers in Immunology)
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ConclusionAnalysis of available evidence shows moderate certainty that the use of probiotics can relieve symptoms of children with cow 's milk allergy. The reduction in certainty is due to imprecise results. Moreover, there is low certainty that probiotics can induce tolerance among children with cow's milk allergy, due to problems of imprecision and attrition bias. In the subgroup analysis,Lactobacillus rhamnosus GG administration likely results in inducing tolerance among infants with suspected cow 's milk allergy. Only studies on CMA were analyzed since no studies were found on probiotics as treatment for other types of food allergy among children. (Source: World Allergy Organization Journal)
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Development of a warp-based automated brain segmentation approach of 3D fluid-attenuated inversion recovery (FLAIR) images and comparison to 3D T1-based segmentation.
3D FLAIR and 3D T1-weighted sequences of 30 healthy subjects (mean age 29.9 ± 8.3 years, 8 female) were acquired on the same 3T MR scanner. Warp-based segmentation was applied for volumetry of total gray matter (GM), white matter (WM), and 116 atlas regions. Segmentation results of both sequences were compared using Pearson correlation (r).
Correlation of GM segmentation results based on FLAIR and T1 was overall good for cortical structures (mean r across all cortical structures = 0.76). Comparatively weaker results were found in the occipital lobe (r = 0.77), central region (mean r = 0.58), basal ganglia (mean r = 0.59), thalamus (r = 0.30), and cerebellum (r = 0.73). FLAIR segmentation underestimated volume of the central region compared to T1, but showed a better anatomic concordance with the occipital lobe on visual review and subcortical structures, when also compared to manual segmentation. Visual analysis of FLAIR-based WM segmentation revealed frequent misclassification of regions of high signal intensity as GM.
Warp-based FLAIR segmentation yields comparable results to T1 segmentation for most cortical GM structures and may provide anatomically more congruent segmentation of subcortical GM structures. Selected cortical regions, especially the central region and total WM, seem to be underestimated on FLAIR segmentation.
(Natural News) Peanuts are high on the list of foods that kids are commonly allergic to these days. And for children who have this allergy, even the smallest exposure to a peanut can result in serious – even life-threatening – anaphylaxis. Experts freely admit that the peanut allergy situation in America is so serious as... (Source: NaturalNews.com)
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Development of a warp-based automated brain segmentation approach of 3D fluid-attenuated inversion recovery (FLAIR) images and comparison to 3D T1-based segmentation.
3D FLAIR and 3D T1-weighted sequences of 30 healthy subjects (mean age 29.9 ± 8.3 years, 8 female) were acquired on the same 3T MR scanner. Warp-based segmentation was applied for volumetry of total gray matter (GM), white matter (WM), and 116 atlas regions. Segmentation results of both sequences were compared using Pearson correlation (r).
Correlation of GM segmentation results based on FLAIR and T1 was overall good for cortical structures (mean r across all cortical structures = 0.76). Comparatively weaker results were found in the occipital lobe (r = 0.77), central region (mean r = 0.58), basal ganglia (mean r = 0.59), thalamus (r = 0.30), and cerebellum (r = 0.73). FLAIR segmentation underestimated volume of the central region compared to T1, but showed a better anatomic concordance with the occipital lobe on visual review and subcortical structures, when also compared to manual segmentation. Visual analysis of FLAIR-based WM segmentation revealed frequent misclassification of regions of high signal intensity as GM.
Warp-based FLAIR segmentation yields comparable results to T1 segmentation for most cortical GM structures and may provide anatomically more congruent segmentation of subcortical GM structures. Selected cortical regions, especially the central region and total WM, seem to be underestimated on FLAIR segmentation.
(Natural News) Peanuts are high on the list of foods that kids are commonly allergic to these days. And for children who have this allergy, even the smallest exposure to a peanut can result in serious – even life-threatening – anaphylaxis. Experts freely admit that the peanut allergy situation in America is so serious as... (Source: NaturalNews.com)
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| Global Anaplastic Thyroid Cancer Drug Market 2018- Genelux Corporation, Immune Pharmaceuticals Inc., Millennium ... Browse Live News (press release) (blog)Top Trends in Global Differentiated Thyroid Cancer Therapeutics Market Size 2016: Industry Forecast till 2024 The News Partner (press release) (blog)Medullary Thyroid Cancer Drug Market: Future Demand, Market Analysis and Outlook to 2023 The Coconutoil Blog (blog)Full coverage |
| Global Anaplastic Thyroid Cancer Drug Market 2018- Genelux Corporation, Immune Pharmaceuticals Inc., Millennium ... Browse Live News (press release) (blog)Top Trends in Global Differentiated Thyroid Cancer Therapeutics Market Size 2016: Industry Forecast till 2024 The News Partner (press release) (blog)Medullary Thyroid Cancer Drug Market: Future Demand, Market Analysis and Outlook to 2023 The Coconutoil Blog (blog)Full coverage |
(Natural News) Peanuts are high on the list of foods that kids are commonly allergic to these days. And for children who have this allergy, even the smallest exposure to a peanut can result in serious – even life-threatening – anaphylaxis. Experts freely admit that the peanut allergy situation in America is so serious as... (Source: NaturalNews.com)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OsJ5Dp
(Natural News) Peanuts are high on the list of foods that kids are commonly allergic to these days. And for children who have this allergy, even the smallest exposure to a peanut can result in serious – even life-threatening – anaphylaxis. Experts freely admit that the peanut allergy situation in America is so serious as... (Source: NaturalNews.com)
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We report the molecular, cellular, and clinical features of 5 patients from 3 kindreds with biallelic mutations in the autosomal LIG1 gene encoding DNA ligase 1. The patients exhibited hypogammaglobulinemia, lymphopenia, increased proportions of circulating γδT cells, and erythrocyte macrocytosis. Clinical severity ranged from a mild antibody deficiency to a combined immunodeficiency requiring hematopoietic stem cell transplantation. Using engineered LIG1-deficient cell lines, we demonstrated chemical and radiation defects associated with the mutant alleles, which variably impaired the DNA repair pathway. We further showed that these LIG1 mutant alleles are amorphic or hypomorphic, and exhibited variably decreased enzymatic activities, which lead to premature release of unligated adenyla...
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We report the molecular, cellular, and clinical features of 5 patients from 3 kindreds with biallelic mutations in the autosomal LIG1 gene encoding DNA ligase 1. The patients exhibited hypogammaglobulinemia, lymphopenia, increased proportions of circulating γδT cells, and erythrocyte macrocytosis. Clinical severity ranged from a mild antibody deficiency to a combined immunodeficiency requiring hematopoietic stem cell transplantation. Using engineered LIG1-deficient cell lines, we demonstrated chemical and radiation defects associated with the mutant alleles, which variably impaired the DNA repair pathway. We further showed that these LIG1 mutant alleles are amorphic or hypomorphic, and exhibited variably decreased enzymatic activities, which lead to premature release of unligated adenyla...
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| Espedilla: Wants to know the cancer fighting foods (Part 5) Sun.StarFull coverage |
This review discusses global trends in cancer mortality and survival, the socioeconomic drivers of those trends, and recent innovations in cancer surgery.
Cancer is a leading cause of death worldwide. Cancer, previously a disease primarily of wealthy countries, is rapidly becoming a leading cause of death in low- and middle-income countries. Major economic forces driving global cancer trends include aging, frailty, and obesity. Alcohol consumption, poor diet, and lack of exercise also contribute to cancer types associated with modifiable causes. Surgery is responsible for 65% of cancer care globally, providing an opportunity for anesthesiologists to improve that care. Anesthesiologists can contribute to cancer remission through perioperative interventions that reduce risk of metastasis and speed return to intended oncologic therapy.
Cancer surgery comprises a large proportion of anesthetic caseload. Good outcomes come from high-volume cancer centers using a multidisciplinary approach.
This review discusses global trends in cancer mortality and survival, the socioeconomic drivers of those trends, and recent innovations in cancer surgery.
Cancer is a leading cause of death worldwide. Cancer, previously a disease primarily of wealthy countries, is rapidly becoming a leading cause of death in low- and middle-income countries. Major economic forces driving global cancer trends include aging, frailty, and obesity. Alcohol consumption, poor diet, and lack of exercise also contribute to cancer types associated with modifiable causes. Surgery is responsible for 65% of cancer care globally, providing an opportunity for anesthesiologists to improve that care. Anesthesiologists can contribute to cancer remission through perioperative interventions that reduce risk of metastasis and speed return to intended oncologic therapy.
Cancer surgery comprises a large proportion of anesthetic caseload. Good outcomes come from high-volume cancer centers using a multidisciplinary approach.
| Low dose cialis and viagra together - Cialis side effects backache - Medical weight loss specialists fargo The Mainstream OnlineFull coverage |
| Low dose cialis and viagra together - Cialis side effects backache - Medical weight loss specialists fargo The Mainstream OnlineFull coverage |
ASHA Convention travels this year to my hometown: the historic city of Boston. While a very walkable city, Boston isn't known for an easy-to-navigate street grid! This selection of apps will help you explore and learn in The Hub (of the solar system, or the universe—whichever you prefer). Revolutionary touring The birthplace of the American Revolution is famous for its many historical sites, from the location of the Boston Massacre (King Street) to the USS Constitution in Charlestown and the Black Heritage Trail® in Beacon Hill. (Boston's black community was a leader in movements to end slavery and espouse equal rights.) See these and other notable sights by walking Boston's historic Freedom Trail®, with guidance from a free National Park Service app (available for iOS and An...
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ASHA Convention travels this year to my hometown: the historic city of Boston. While a very walkable city, Boston isn't known for an easy-to-navigate street grid! This selection of apps will help you explore and learn in The Hub (of the solar system, or the universe—whichever you prefer). Revolutionary touring The birthplace of the American Revolution is famous for its many historical sites, from the location of the Boston Massacre (King Street) to the USS Constitution in Charlestown and the Black Heritage Trail® in Beacon Hill. (Boston's black community was a leader in movements to end slavery and espouse equal rights.) See these and other notable sights by walking Boston's historic Freedom Trail®, with guidance from a free National Park Service app (available for iOS and An...
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ASHA Convention travels this year to my hometown: the historic city of Boston. While a very walkable city, Boston isn't known for an easy-to-navigate street grid! This selection of apps will help you explore and learn in The Hub (of the solar system, or the universe—whichever you prefer). Revolutionary touring The birthplace of the American Revolution is famous for its many historical sites, from the location of the Boston Massacre (King Street) to the USS Constitution in Charlestown and the Black Heritage Trail® in Beacon Hill. (Boston's black community was a leader in movements to end slavery and espouse equal rights.) See these and other notable sights by walking Boston's historic Freedom Trail®, with guidance from a free National Park Service app (available for iOS and An...
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
ASHA Convention travels this year to my hometown: the historic city of Boston. While a very walkable city, Boston isn't known for an easy-to-navigate street grid! This selection of apps will help you explore and learn in The Hub (of the solar system, or the universe—whichever you prefer). Revolutionary touring The birthplace of the American Revolution is famous for its many historical sites, from the location of the Boston Massacre (King Street) to the USS Constitution in Charlestown and the Black Heritage Trail® in Beacon Hill. (Boston's black community was a leader in movements to end slavery and espouse equal rights.) See these and other notable sights by walking Boston's historic Freedom Trail®, with guidance from a free National Park Service app (available for iOS and An...
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Oral vancomycin is a first-line treatment for severe Clostridium difficile colitis. Oral vancomycin is perceived to lack systemic absorption or systemic adverse effects; however, a few cases of hypersensitivity to oral vancomycin have been reported, all in hospitalized patients.
In the present case, a 66-year-old woman with end-stage neurodegenerative disease residing in a long-term care facility developed a maculopapular rash following treatment with enteral vancomycin for recurrent C. difficile colitis. The rash resolved after withdrawal of the drug.
Rashes associated with oral vancomycin treatment include maculopapular rash, urticaria, red man syndrome, and linear IgA bullous dermatitis. Risk factors for systemic vancomycin absorption include renal insufficiency, severe intestinal inflammation, and high vancomycin dose and duration. Routine serum testing of vancomycin levels, even in these high risk cases, is not recommended. Clinicians should be aware that enteral vancomycin can cause hypersensitivity reactions which may be serious.
Oral vancomycin is a first-line treatment for severe Clostridium difficile colitis. Oral vancomycin is perceived to lack systemic absorption or systemic adverse effects; however, a few cases of hypersensitivity to oral vancomycin have been reported, all in hospitalized patients.
In the present case, a 66-year-old woman with end-stage neurodegenerative disease residing in a long-term care facility developed a maculopapular rash following treatment with enteral vancomycin for recurrent C. difficile colitis. The rash resolved after withdrawal of the drug.
Rashes associated with oral vancomycin treatment include maculopapular rash, urticaria, red man syndrome, and linear IgA bullous dermatitis. Risk factors for systemic vancomycin absorption include renal insufficiency, severe intestinal inflammation, and high vancomycin dose and duration. Routine serum testing of vancomycin levels, even in these high risk cases, is not recommended. Clinicians should be aware that enteral vancomycin can cause hypersensitivity reactions which may be serious.
ASHA Convention travels this year to my hometown: the historic city of Boston. While a very walkable city, Boston isn't known for an easy-to-navigate street grid! This selection of apps will help you explore and learn in The Hub (of the solar system, or the universe—whichever you prefer). Revolutionary touring The birthplace of the American Revolution is famous for its many historical sites, from the location of the Boston Massacre (King Street) to the USS Constitution in Charlestown and the Black Heritage Trail® in Beacon Hill. (Boston's black community was a leader in movements to end slavery and espouse equal rights.) See these and other notable sights by walking Boston's historic Freedom Trail®, with guidance from a free National Park Service app (available for iOS and An...
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ASHA Convention travels this year to my hometown: the historic city of Boston. While a very walkable city, Boston isn't known for an easy-to-navigate street grid! This selection of apps will help you explore and learn in The Hub (of the solar system, or the universe—whichever you prefer). Revolutionary touring The birthplace of the American Revolution is famous for its many historical sites, from the location of the Boston Massacre (King Street) to the USS Constitution in Charlestown and the Black Heritage Trail® in Beacon Hill. (Boston's black community was a leader in movements to end slavery and espouse equal rights.) See these and other notable sights by walking Boston's historic Freedom Trail®, with guidance from a free National Park Service app (available for iOS and An...
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At NIH, we are heavily invested in our workforce and in understanding the barriers they face. What characteristics do they share? How do they compete in the current hypercompetitive environment? When do they stop applying to NIH (drop out), even after receiving their first award? Staff from the National Institute of Allergy and Infectious Diseases (NIAID) delve into these questions in a paper published recently in PLOS ONE , whose findings I'd like to highlight today. Here, Drs. Patricia Haggerty and Matthew Fenton looked at factors that may contribute to the success of early-career investigators and if these factors affect all junior researchers equally. This analysis focused on a cohort of investigators who received their first NIH R01-equivalent research grant (referred to as R01-e) a...
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At NIH, we are heavily invested in our workforce and in understanding the barriers they face. What characteristics do they share? How do they compete in the current hypercompetitive environment? When do they stop applying to NIH (drop out), even after receiving their first award? Staff from the National Institute of Allergy and Infectious Diseases (NIAID) delve into these questions in a paper published recently in PLOS ONE , whose findings I'd like to highlight today. Here, Drs. Patricia Haggerty and Matthew Fenton looked at factors that may contribute to the success of early-career investigators and if these factors affect all junior researchers equally. This analysis focused on a cohort of investigators who received their first NIH R01-equivalent research grant (referred to as R01-e) a...
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Internal Medicine Journal,Volume 48, Issue S6, Page 8-8, November 2018. (Source: Internal Medicine Journal)
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Th2 immune response is critical for allergic asthma pathogenesis. Molecular mechanisms for regulating Th2 immunity are still not well understood. Here we report that the ubiquitin-specific protease USP38 is crucial for Th2-mediated allergic asthma. TCR stimulation up-regulated the USP38 level, and USP38 in turn mediated the protein stabilization of JunB, a transcription factor specific for Th2 development. Consequently, USP38 was specifically required for TCR-induced production of Th2 cytokines and Th2 development both in vitro and in vivo, and USP38-deficient mice were resistant to asthma pathogenesis induced by OVA or HDM. Mechanistically, USP38 directly associated with JunB, deubiquitinated Lys-48–linked poly-ubiquitination of JunB, and consequently blocked TCR-induced JunB turnov...
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This study unveils a novel innate immune response to an enteropathogen, which implicates gp38+ stromal cells and locks intestinal villus invasion, but favors colitis. (Source: The Journal of Experimental Medicine)
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Internal Medicine Journal,Volume 48, Issue S6, Page 12-12, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 14-14, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 15-16, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 27-28, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 9-9, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 17-17, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 13-13, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 16-16, November 2018. (Source: Internal Medicine Journal)
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Monocytes are crucial immune cells involved in regulation of inflammation either directly or via differentiation into macrophages in tissues. However, many aspects of how their function is controlled in health and disease are not understood. Here we show that human blood monocytes activate high levels of the cytokine TGFβ, a pathway that is not evident in mouse monocytes. Human CD14+, but not CD16+, monocytes activate TGFβ via expression of the integrin αvβ8 and matrix metalloproteinase 14, which dampens their production of TNFα in response to LPS. Additionally, when monocytes differentiate into macrophages, integrin expression and TGFβ-activating ability are maintained in anti-inflammatory macrophages but down-regulated in pro-inflammatory macrophages. In t...
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Internal Medicine Journal,Volume 48, Issue S6, Page 8-8, November 2018. (Source: Internal Medicine Journal)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Internal Medicine Journal,Volume 48, Issue S6, Page 6-6, November 2018. (Source: Internal Medicine Journal)
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Th2 immune response is critical for allergic asthma pathogenesis. Molecular mechanisms for regulating Th2 immunity are still not well understood. Here we report that the ubiquitin-specific protease USP38 is crucial for Th2-mediated allergic asthma. TCR stimulation up-regulated the USP38 level, and USP38 in turn mediated the protein stabilization of JunB, a transcription factor specific for Th2 development. Consequently, USP38 was specifically required for TCR-induced production of Th2 cytokines and Th2 development both in vitro and in vivo, and USP38-deficient mice were resistant to asthma pathogenesis induced by OVA or HDM. Mechanistically, USP38 directly associated with JunB, deubiquitinated Lys-48–linked poly-ubiquitination of JunB, and consequently blocked TCR-induced JunB turnov...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qvN2O7
This study unveils a novel innate immune response to an enteropathogen, which implicates gp38+ stromal cells and locks intestinal villus invasion, but favors colitis. (Source: The Journal of Experimental Medicine)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Qmre2Z
Internal Medicine Journal,Volume 48, Issue S6, Page 17-17, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 12-12, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 5-5, November 2018. (Source: Internal Medicine Journal)
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A coding variant of the inflammatory bowel disease (IBD) risk gene ATG16L1 has been associated with defective autophagy and deregulation of endoplasmic reticulum (ER) function. IL-22 is a barrier protective cytokine by inducing regeneration and antimicrobial responses in the intestinal mucosa. We show that ATG16L1 critically orchestrates IL-22 signaling in the intestinal epithelium. IL-22 stimulation physiologically leads to transient ER stress and subsequent activation of STING-dependent type I interferon (IFN-I) signaling, which is augmented in Atg16l1IEC intestinal organoids. IFN-I signals amplify epithelial TNF production downstream of IL-22 and contribute to necroptotic cell death. In vivo, IL-22 treatment in Atg16l1IEC and Atg16l1IEC/Xbp1IEC mice potentiates endogenous ileal inflamma...
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Internal Medicine Journal,Volume 48, Issue S6, Page 14-14, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 15-16, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 27-28, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 9-9, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 16-16, November 2018. (Source: Internal Medicine Journal)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Internal Medicine Journal,Volume 48, Issue S6, Page 14-14, November 2018. (Source: Internal Medicine Journal)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Internal Medicine Journal,Volume 48, Issue S6, Page 28-28, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 17-17, November 2018. (Source: Internal Medicine Journal)
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Internal Medicine Journal,Volume 48, Issue S6, Page 13-13, November 2018. (Source: Internal Medicine Journal)
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The burden of disease of food allergy is increasing worldwide. The standard of management is allergen avoidance and symptomatic treatment. Probiotics have been proposed to be beneficial for treatment and prevention of food allergy.
To determine the effectiveness of probiotic administration in treating food allergies among pediatric patients.
A systematic search of electronic medical literature databases was conducted. Manual search of the reference lists and search for unpublished articles were also done. All randomized controlled trials available from inception until February 19, 2018 were retrieved. The primary outcome of interest was relief of allergic symptoms, while the secondary outcome of interest was inducement of tolerance. Two independent authors did the search, screening, appraisal, and data abstraction. Data analysis and synthesis were done using RevMan 5.3 software. Subgroup analysis was done based on the probiotic strains and time periods in measuring the outcome. Exclusion sensitivity analysis was also done.
Nine trials involving 895 pediatric patients with cow's milk allergy (CMA) were included in the review. The primary outcome of interest, relief of symptoms, was measured using the scoring index for eczema. Pooled results from two studies showed larger reduction in the scoring index among patients given probiotics, but this effect was imprecise (MD -1.30, 95% CI -3.88, 1.28). For the secondary outcome of interest, pooled results from four studies showed benefit of probiotics in inducing tolerance, but again this result is imprecise with significant heterogeneity (RR 0.58, 95% CI 0.34, 1.00). Subgroup analysis per probiotic strain showed benefit of Lactobacillus rhamnosus GG in inducing tolerance based on two studies involving infants with suspected cow's milk allergy (RR = 0.41, 95% CI 0.28 to 0.62). Another subgroup analysis showed a duration-dependent effect associated with probiotic usage, with inducement of tolerance noted after at least 2 years (RR = 0.44, 95% CI 0.29 to 0.67).
Analysis of available evidence shows moderate certainty that the use of probiotics can relieve symptoms of children with cow's milk allergy. The reduction in certainty is due to imprecise results. Moreover, there is low certainty that probiotics can induce tolerance among children with cow's milk allergy, due to problems of imprecision and attrition bias. In the subgroup analysis, Lactobacillus rhamnosus GG administration likely results in inducing tolerance among infants with suspected cow's milk allergy. Only studies on CMA were analyzed since no studies were found on probiotics as treatment for other types of food allergy among children.
The burden of disease of food allergy is increasing worldwide. The standard of management is allergen avoidance and symptomatic treatment. Probiotics have been proposed to be beneficial for treatment and prevention of food allergy.
To determine the effectiveness of probiotic administration in treating food allergies among pediatric patients.
A systematic search of electronic medical literature databases was conducted. Manual search of the reference lists and search for unpublished articles were also done. All randomized controlled trials available from inception until February 19, 2018 were retrieved. The primary outcome of interest was relief of allergic symptoms, while the secondary outcome of interest was inducement of tolerance. Two independent authors did the search, screening, appraisal, and data abstraction. Data analysis and synthesis were done using RevMan 5.3 software. Subgroup analysis was done based on the probiotic strains and time periods in measuring the outcome. Exclusion sensitivity analysis was also done.
Nine trials involving 895 pediatric patients with cow's milk allergy (CMA) were included in the review. The primary outcome of interest, relief of symptoms, was measured using the scoring index for eczema. Pooled results from two studies showed larger reduction in the scoring index among patients given probiotics, but this effect was imprecise (MD -1.30, 95% CI -3.88, 1.28). For the secondary outcome of interest, pooled results from four studies showed benefit of probiotics in inducing tolerance, but again this result is imprecise with significant heterogeneity (RR 0.58, 95% CI 0.34, 1.00). Subgroup analysis per probiotic strain showed benefit of Lactobacillus rhamnosus GG in inducing tolerance based on two studies involving infants with suspected cow's milk allergy (RR = 0.41, 95% CI 0.28 to 0.62). Another subgroup analysis showed a duration-dependent effect associated with probiotic usage, with inducement of tolerance noted after at least 2 years (RR = 0.44, 95% CI 0.29 to 0.67).
Analysis of available evidence shows moderate certainty that the use of probiotics can relieve symptoms of children with cow's milk allergy. The reduction in certainty is due to imprecise results. Moreover, there is low certainty that probiotics can induce tolerance among children with cow's milk allergy, due to problems of imprecision and attrition bias. In the subgroup analysis, Lactobacillus rhamnosus GG administration likely results in inducing tolerance among infants with suspected cow's milk allergy. Only studies on CMA were analyzed since no studies were found on probiotics as treatment for other types of food allergy among children.
The purpose of this study was to assess host-derived parameters around dental zirconia and titanium implants and natural teeth during the occurrence of mucositis. After 4 weeks of perfect oral hygiene, 16 clinically profiled patients were asked to refrain from oral hygiene for 2 weeks, resulting in experimental plaque accumulation. This was followed by 4 weeks of perfect oral hygiene to reverse the inflammation. Immunological samples were analyzed for interleukin 6 (IL-6), tumour necrosis factor alpha (TNF-α), and interleukin 1β (IL-1β).
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Nasoalveolar moulding is a presurgical orthopaedic technique used to improve the outcomes of bilateral clefts. However, the lack of a validated scale tailored to bilateral clefts makes it difficult to quantify the merits of nasoalveolar moulding and compare it to other techniques. In this study, a recently published anatomical subunit scale was used to evaluate and compare the early effects of nasoalveolar moulding. Two groups of similarly treated bilateral cleft patients were included: one in which patients underwent presurgical nasoalveolar moulding and one in which they did not.
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Immunology Interest GroupAir date: 11/7/2018 4:15:00 PM (Source: Videocast - All Events)
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The purpose of this study was to assess host-derived parameters around dental zirconia and titanium implants and natural teeth during the occurrence of mucositis. After 4 weeks of perfect oral hygiene, 16 clinically profiled patients were asked to refrain from oral hygiene for 2 weeks, resulting in experimental plaque accumulation. This was followed by 4 weeks of perfect oral hygiene to reverse the inflammation. Immunological samples were analyzed for interleukin 6 (IL-6), tumour necrosis factor alpha (TNF-α), and interleukin 1β (IL-1β).
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2D5lkPG
Nasoalveolar moulding is a presurgical orthopaedic technique used to improve the outcomes of bilateral clefts. However, the lack of a validated scale tailored to bilateral clefts makes it difficult to quantify the merits of nasoalveolar moulding and compare it to other techniques. In this study, a recently published anatomical subunit scale was used to evaluate and compare the early effects of nasoalveolar moulding. Two groups of similarly treated bilateral cleft patients were included: one in which patients underwent presurgical nasoalveolar moulding and one in which they did not.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PbKtiZ
Immunology Interest GroupAir date: 11/7/2018 4:15:00 PM (Source: Videocast - All Events)
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Associated injuries (AIs) are hypothesized to be frequent in geriatric zygomatico-orbital (ZMO) fractures. The study aim was to determine the relationship between ZMO fractures and AIs in geriatric patients in comparison to younger adults.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qt8DXz
Associated injuries (AIs) are hypothesized to be frequent in geriatric zygomatico-orbital (ZMO) fractures. The study aim was to determine the relationship between ZMO fractures and AIs in geriatric patients in comparison to younger adults.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qt8DXz
| NCRI: Highlights from the Annual Conference MedPage TodayFull coverage |
| NCRI: Highlights from the Annual Conference MedPage TodayFull coverage |
Associated injuries (AIs) are hypothesized to be frequent in geriatric zygomatico-orbital (ZMO) fractures. The study aim was to determine the relationship between ZMO fractures and AIs in geriatric patients in comparison to younger adults.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qt8DXz
Associated injuries (AIs) are hypothesized to be frequent in geriatric zygomatico-orbital (ZMO) fractures. The study aim was to determine the relationship between ZMO fractures and AIs in geriatric patients in comparison to younger adults.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qt8DXz
October 17, 2018—The American Thyroid Association (ATA) announces with pleasure that Elizabeth Pearce, MD, MSc, began a one-year term as president of the Board of Directors at the close of the Annual Meeting, October 7 in Washington, DC. Dr. Pearce has served for the past year as President-Elect.
Newly elected board members are:
Martha Zeiger, MD, President-Elect
Jacqueline Jonklaas, MD, Secretary-Elect
Joshua Klopper, MD, Director
Angela Leung, MD, MSc, Director
Elizabeth Pearce, MD, MSc, Board President
Dr. Pearce is professor of medicine in the Endocrinology, Diabetes, and Nutrition Section at Boston University School of Medicine. She received her undergraduate and medical degrees from Harvard and a masters' degree in epidemiology from the Boston University School of Public Health. She completed her residency in internal medicine at Beth Israel Deaconess Medical Center, and her fellowship in endocrinology at Boston University under the mentorship of Dr. Lewis Braverman. Her research interests include: the sufficiency of dietary iodine in the U.S. and globally; thyroid function in pregnancy; thyroidal effects of exposure to environmental endocrine disruptors; and the cardiovascular effects of subclinical thyroid dysfunction. She has been part of the leadership of the Iodine Global Network (IGN; formerly ICCIDD) since 2009. She is a member of the AACE Thyroid Disease State Network and serves as faculty for the Endocrine Society's annual board review course. She has served on multiple editorial boards, including those for Endocrine Practice, Journal of Clinical Endocrinology and Metabolism, Clinical Endocrinology, European Journal of Clinical Nutrition, and Lancet Diabetes & Endocrinology.
Dr. Pearce has been a member of the American Thyroid Association since 2000. She has chaired both the ATA's Publications and Public Health Committees. She cochaired the 2012 Annual Meeting Program Committee and the 2009 and 2016 Spring Symposia and was a member of the Program Committee for the 2015 International Thyroid Congress. Dr. Pearce has also served as a member of the ATA Finance Committee and the Guidelines Policy Task Force. She was one of the leaders in establishing the ATA's Braverman Lectureship and cochaired the task force for the 2017 Pregnancy Guidelines. She is associate editor for both Thyroid and Clinical Thyroidology journals. She served as a member of the Board of Directors from 2009 to 2013 and again as president-elect for the past year. Dr. Pearce was the 2011 recipient of the Van Meter Award for outstanding contributions to research on the thyroid gland.
Martha Zeiger, MD, President-Elect
Dr. Martha Zeiger is the S. Hurt Watts professor and chair of surgery at the University of Virginia School of Medicine. Regarded as a world leader in endocrine surgery, she is also an expert in the molecular aspects of thyroid cancer and an experienced academic leader. Her surgical training includes a surgical oncology fellowship, focused on endocrine surgery, at the National Cancer Institute, NIH, prior to joining the faculty at Johns Hopkins University School of Medicine in 1993. There, she built her endocrine surgery practice, established an endocrine surgery fellowship program, and directed an NIH-funded molecular biology laboratory for over 20 years. Today, her research team continues at Johns Hopkins, focusing on the molecular aspects of thyroid cancer.
While at John Hopkins, Dr. Zeiger took the lead as: associate dean for postdoctoral affairs; professor of surgery, oncology, cellular and molecular medicine; associate vice chair of surgery faculty development; and medical director of business development, strategic alliance, and venture technology. While associate dean for postdoctoral affairs, she oversaw 1,200 research fellows in the School of Medicine. She also established a formal program for international postdoctoral fellows.
Dr. Zeiger has held numerous leadership positions in national medical societies: the American Association of Endocrine Surgeons, the American Association of Clinical Endocrinologists, and the ATA. Through AAES, she founded Endocrine Surgery University, an annual course for all endocrine surgery fellows in North America.
She has served on the ATA Board of Directors and many ATA committees, including publications, membership, conflict of interest task force. She co-chaired the annual meeting program committee in 2011.
Jacqueline Jonklaas, MD, Secretary-Elect
Dr. Jonklaas is currently a professor in the endocrinology division at Georgetown University in Washington, DC, where she completed her medical degree, residency, and fellowship training. As a clinical researcher in the thyroid field, her time is divided between research, clinical activities, and teaching. Dr. Jonklaas's research has focused on the management of hypothyroidism and thyroid cancer. Current research involves examining patient-reported outcomes after radioiodine therapy. Her recent publications address topics such as how to optimize the treatment of hypothyroidism and the outcomes of thyroid cancer patients based on their treatment, age, and gender.
She is the program director of the Georgetown University Clinical Research Unit. She is involved in translational research and the activities of the Georgetown University's Clinical and Translational Science Award. She recently directed the endocrinology courses for Georgetown University Medical School's first- and second-year medical students. She currently teaches in these courses.
She serves on the editorial board of the Journal of Clinical Endocrinology and Metabolism. She is involved in teaching at the national level as a member of the Endocrine Society Self-Assessment Committee.
Dr. Jonklaas has been a member of the ATA since 1999. She has served on several past ATA committees, including the Patient Education and Advocacy Committee, the Surgical Task Force Committee, and the Awards Committee. She was cochair of the ATA Task Force on Thyroid Hormone Replacement, whose guidelines were published in 2014. She previously served on the Board of Directors from 2013–2017, and recently completed a term as the cochair of the Guidelines and Statement Committee. Currently she serves on the Program Committee. She also serves on the editorial board of the ATA journal Thyroid.
Joshua Klopper, MD, Director (Endocrinologist in Community Practice)
D
r. Klopper joined the Colorado Permanente Medical Group (CPMG) of Kaiser Permanente in July 2015 and was appointed chief of the department in April 2016. He was appointed associate clinical professor of medicine in the Division of Endocrinology, Metabolism, and Diabetes at the University of Colorado School of Medicine in October 2015.
He earned a B.S. in psychology in 1995 from Indiana University in Bloomington, Indiana. In 1999 he received his medical degree from the Emory University School of Medicine in Atlanta, Georgia. He completed his internship and residency in internal medicine at the University of Colorado Health Sciences Center in 2002. Dr. Klopper then completed a postdoctoral research fellowship in the Endocrinology Division, prior to starting his endocrinology fellowship at the University of Colorado at Denver Health Sciences Center, completed in 2006.
Dr. Klopper was a full-time faculty member in the Division of Endocrinology at the University of Colorado School of Medicine from 2006–2015, where he specialized in the evaluation and management of thyroid nodules and thyroid cancer, including advanced thyroid cancer. During his academic career, he received grant funding at the local, state, and national level including from the American Cancer Society. He has published original research on the evaluation and management of thyroid nodules and advanced thyroid cancer and has written several book chapters and reviews. Additionally, he participated as an original member of the Thyroid Cancer Care Collaborative development committee. He has served on the Clinical Affairs and Development committees of the ATA as well as on the Endocrine Society Annual Meeting Steering committee. Currently, Dr. Klopper is on the Medical Specialty Peer Review Committee for CPMG and has been codirector of the Endocrine Society's Introductory Hands-On Thyroid Ultrasound Workshop since 2014.
Angela Leung, MD, MSc, Director (Endocrinologist in Academic Practice)
Angela M. Leung, MD, MSc, is an assistant professor of medicine in the Division of Endocrinology, Diabetes, and Metabolism at the UCLA David Geffen School of Medicine and in the VA Greater Los Angeles Healthcare System, and an associate program director of the UCLA/VA endocrinology fellowship program.
She received her undergraduate degree at Occidental College in Los Angeles, her medical degree from the Boston University School of Medicine, and a masters' degree in epidemiology from the Boston University School of Public Health. She completed her internal medicine residency and a clinical and research endocrine fellowship at Boston University Medical Center. Her research areas of interest include iodine deficiency and excess, thyroid toxicant exposures, and maternal-child thyroid health. She is a member of the AACE Thyroid Disease State Network and the editorial board of Endocrine Practice, has participated in the AACE Endocrine Training Support Committee, and was a recipient of the Endocrine Society Early Investigator Award. She has reviewed for several NIH standing and early-career award endocrine study sections; for the U.S. EPA's Biologically-Based Dose Response model to guide perchlorate regulation in U.S. drinking water; and for the EPA's draft toxicity assessments of the thyroid disruptors GenX and perfluorobutane sulfonate. Through the Endocrine Society, she participates in reviewing the effects of thyroid toxicants for the Organization for Economic Cooperation and Development, a global initiative focused on the regulatory policies of endocrine disruptors.
Dr. Leung has been involved in multiple ATA programs and initiatives. She serves on the editorial boards of three ATA journals: Thyroid, Clinical Thyroidology, and Clinical Thyroidology for the Public. She is past Chair of the ATA Public Health Committee (2012–16), during which she led the publication of the ATA's statements on iodine excess and the use of potassium iodide in nuclear accidents; was a member of the Program Committee for the 2016 ATA Annual Meeting; and served as clinical cochair for the 2017 ATA Annual Meeting in Victoria, British Columbia.
The ATA thanks this year's Nominating Committee, chaired by David Steward, and the Secretary-Elect Selection Task Force, chaired by John Morris. We are extremely grateful to all who serve on the Board of Directors. Special thanks go to those who will retire from the Board this year: Regina Castro, MD, Christine Spitzweg, MD, and outgoing Past-President John C. Morris, MD.
###
The American Thyroid Association (ATA) is the leading worldwide organization dedicated to the advancement, understanding, prevention, diagnosis, and treatment of thyroid disorders and thyroid cancer. ATA is an international membership medical society with over 1,700 members from 43 countries around the world. Celebrating its 95th anniversary, the ATA continues to deliver its mission of being devoted to thyroid biology and to the prevention and treatment of thyroid disease through excellence in research, clinical care, education, and public health. These efforts are carried out via several key endeavors:
The ATA promotes thyroid awareness and information online through Clinical Thyroidology for the Public and extensive, authoritative explanations of thyroid disease and thyroid cancer in both English and Spanish. The ATA website serves as the clinical resource for patients and the public who look for reliable information on the Internet. Every fifth year, the American Thyroid Association joins with the Latin American Thyroid Society, the European Thyroid Association, and the Asia and Oceania Thyroid Association to cosponsor the International Thyroid Congress (ITC).
The post American Thyroid Association: Dr. Elizabeth Pearce to Lead 2018-2019 Board of Directors appeared first on American Thyroid Association.
October 17, 2018—The American Thyroid Association (ATA) announces with pleasure that Elizabeth Pearce, MD, MSc, began a one-year term as president of the Board of Directors at the close of the Annual Meeting, October 7 in Washington, DC. Dr. Pearce has served for the past year as President-Elect.
Newly elected board members are:
Martha Zeiger, MD, President-Elect
Jacqueline Jonklaas, MD, Secretary-Elect
Joshua Klopper, MD, Director
Angela Leung, MD, MSc, Director
Elizabeth Pearce, MD, MSc, Board President
Dr. Pearce is professor of medicine in the Endocrinology, Diabetes, and Nutrition Section at Boston University School of Medicine. She received her undergraduate and medical degrees from Harvard and a masters' degree in epidemiology from the Boston University School of Public Health. She completed her residency in internal medicine at Beth Israel Deaconess Medical Center, and her fellowship in endocrinology at Boston University under the mentorship of Dr. Lewis Braverman. Her research interests include: the sufficiency of dietary iodine in the U.S. and globally; thyroid function in pregnancy; thyroidal effects of exposure to environmental endocrine disruptors; and the cardiovascular effects of subclinical thyroid dysfunction. She has been part of the leadership of the Iodine Global Network (IGN; formerly ICCIDD) since 2009. She is a member of the AACE Thyroid Disease State Network and serves as faculty for the Endocrine Society's annual board review course. She has served on multiple editorial boards, including those for Endocrine Practice, Journal of Clinical Endocrinology and Metabolism, Clinical Endocrinology, European Journal of Clinical Nutrition, and Lancet Diabetes & Endocrinology.
Dr. Pearce has been a member of the American Thyroid Association since 2000. She has chaired both the ATA's Publications and Public Health Committees. She cochaired the 2012 Annual Meeting Program Committee and the 2009 and 2016 Spring Symposia and was a member of the Program Committee for the 2015 International Thyroid Congress. Dr. Pearce has also served as a member of the ATA Finance Committee and the Guidelines Policy Task Force. She was one of the leaders in establishing the ATA's Braverman Lectureship and cochaired the task force for the 2017 Pregnancy Guidelines. She is associate editor for both Thyroid and Clinical Thyroidology journals. She served as a member of the Board of Directors from 2009 to 2013 and again as president-elect for the past year. Dr. Pearce was the 2011 recipient of the Van Meter Award for outstanding contributions to research on the thyroid gland.
Martha Zeiger, MD, President-Elect
Dr. Martha Zeiger is the S. Hurt Watts professor and chair of surgery at the University of Virginia School of Medicine. Regarded as a world leader in endocrine surgery, she is also an expert in the molecular aspects of thyroid cancer and an experienced academic leader. Her surgical training includes a surgical oncology fellowship, focused on endocrine surgery, at the National Cancer Institute, NIH, prior to joining the faculty at Johns Hopkins University School of Medicine in 1993. There, she built her endocrine surgery practice, established an endocrine surgery fellowship program, and directed an NIH-funded molecular biology laboratory for over 20 years. Today, her research team continues at Johns Hopkins, focusing on the molecular aspects of thyroid cancer.
While at John Hopkins, Dr. Zeiger took the lead as: associate dean for postdoctoral affairs; professor of surgery, oncology, cellular and molecular medicine; associate vice chair of surgery faculty development; and medical director of business development, strategic alliance, and venture technology. While associate dean for postdoctoral affairs, she oversaw 1,200 research fellows in the School of Medicine. She also established a formal program for international postdoctoral fellows.
Dr. Zeiger has held numerous leadership positions in national medical societies: the American Association of Endocrine Surgeons, the American Association of Clinical Endocrinologists, and the ATA. Through AAES, she founded Endocrine Surgery University, an annual course for all endocrine surgery fellows in North America.
She has served on the ATA Board of Directors and many ATA committees, including publications, membership, conflict of interest task force. She co-chaired the annual meeting program committee in 2011.
Jacqueline Jonklaas, MD, Secretary-Elect
Dr. Jonklaas is currently a professor in the endocrinology division at Georgetown University in Washington, DC, where she completed her medical degree, residency, and fellowship training. As a clinical researcher in the thyroid field, her time is divided between research, clinical activities, and teaching. Dr. Jonklaas's research has focused on the management of hypothyroidism and thyroid cancer. Current research involves examining patient-reported outcomes after radioiodine therapy. Her recent publications address topics such as how to optimize the treatment of hypothyroidism and the outcomes of thyroid cancer patients based on their treatment, age, and gender.
She is the program director of the Georgetown University Clinical Research Unit. She is involved in translational research and the activities of the Georgetown University's Clinical and Translational Science Award. She recently directed the endocrinology courses for Georgetown University Medical School's first- and second-year medical students. She currently teaches in these courses.
She serves on the editorial board of the Journal of Clinical Endocrinology and Metabolism. She is involved in teaching at the national level as a member of the Endocrine Society Self-Assessment Committee.
Dr. Jonklaas has been a member of the ATA since 1999. She has served on several past ATA committees, including the Patient Education and Advocacy Committee, the Surgical Task Force Committee, and the Awards Committee. She was cochair of the ATA Task Force on Thyroid Hormone Replacement, whose guidelines were published in 2014. She previously served on the Board of Directors from 2013–2017, and recently completed a term as the cochair of the Guidelines and Statement Committee. Currently she serves on the Program Committee. She also serves on the editorial board of the ATA journal Thyroid.
Joshua Klopper, MD, Director (Endocrinologist in Community Practice)
Dr. Klopper joined the Colorado Permanente Medical Group (CPMG) of Kaiser Permanente in July 2015 and was appointed chief of the department in April 2016. He was appointed associate clinical professor of medicine in the Division of Endocrinology, Metabolism, and Diabetes at the University of Colorado School of Medicine in October 2015.
He earned a B.S. in psychology in 1995 from Indiana University in Bloomington, Indiana. In 1999 he received his medical degree from the Emory University School of Medicine in Atlanta, Georgia. He completed his internship and residency in internal medicine at the University of Colorado Health Sciences Center in 2002. Dr. Klopper then completed a postdoctoral research fellowship in the Endocrinology Division, prior to starting his endocrinology fellowship at the University of Colorado at Denver Health Sciences Center, completed in 2006.
Dr. Klopper was a full-time faculty member in the Division of Endocrinology at the University of Colorado School of Medicine from 2006–2015, where he specialized in the evaluation and management of thyroid nodules and thyroid cancer, including advanced thyroid cancer. During his academic career, he received grant funding at the local, state, and national level including from the American Cancer Society. He has published original research on the evaluation and management of thyroid nodules and advanced thyroid cancer and has written several book chapters and reviews. Additionally, he participated as an original member of the Thyroid Cancer Care Collaborative development committee. He has served on the Clinical Affairs and Development committees of the ATA as well as on the Endocrine Society Annual Meeting Steering committee. Currently, Dr. Klopper is on the Medical Specialty Peer Review Committee for CPMG and has been codirector of the Endocrine Society's Introductory Hands-On Thyroid Ultrasound Workshop since 2014.
Angela Leung, MD, MSc, Director (Endocrinologist in Academic Practice)
Angela M. Leung, MD, MSc, is an assistant professor of medicine in the Division of Endocrinology, Diabetes, and Metabolism at the UCLA David Geffen School of Medicine and in the VA Greater Los Angeles Healthcare System, and an associate program director of the UCLA/VA endocrinology fellowship program.
She received her undergraduate degree at Occidental College in Los Angeles, her medical degree from the Boston University School of Medicine, and a masters' degree in epidemiology from the Boston University School of Public Health. She completed her internal medicine residency and a clinical and research endocrine fellowship at Boston University Medical Center. Her research areas of interest include iodine deficiency and excess, thyroid toxicant exposures, and maternal-child thyroid health. She is a member of the AACE Thyroid Disease State Network and the editorial board of Endocrine Practice, has participated in the AACE Endocrine Training Support Committee, and was a recipient of the Endocrine Society Early Investigator Award. She has reviewed for several NIH standing and early-career award endocrine study sections; for the U.S. EPA's Biologically-Based Dose Response model to guide perchlorate regulation in U.S. drinking water; and for the EPA's draft toxicity assessments of the thyroid disruptors GenX and perfluorobutane sulfonate. Through the Endocrine Society, she participates in reviewing the effects of thyroid toxicants for the Organization for Economic Cooperation and Development, a global initiative focused on the regulatory policies of endocrine disruptors.
Dr. Leung has been involved in multiple ATA programs and initiatives. She serves on the editorial boards of three ATA journals: Thyroid, Clinical Thyroidology, and Clinical Thyroidology for the Public. She is past Chair of the ATA Public Health Committee (2012–16), during which she led the publication of the ATA's statements on iodine excess and the use of potassium iodide in nuclear accidents; was a member of the Program Committee for the 2016 ATA Annual Meeting; and served as clinical cochair for the 2017 ATA Annual Meeting in Victoria, British Columbia.
The ATA thanks this year's Nominating Committee, chaired by David Steward, and the Secretary-Elect Selection Task Force, chaired by John Morris. We are extremely grateful to all who serve on the Board of Directors. Special thanks go to those who will retire from the Board this year: Regina Castro, MD, Christine Spitzweg, MD, and outgoing Past-President John C. Morris, MD.
###
The American Thyroid Association (ATA) is the leading worldwide organization dedicated to the advancement, understanding, prevention, diagnosis, and treatment of thyroid disorders and thyroid cancer. ATA is an international membership medical society with over 1,700 members from 43 countries around the world. Celebrating its 95th anniversary, the ATA continues to deliver its mission of being devoted to thyroid biology and to the prevention and treatment of thyroid disease through excellence in research, clinical care, education, and public health. These efforts are carried out via several key endeavors:
The ATA promotes thyroid awareness and information online through Clinical Thyroidology for the Public and extensive, authoritative explanations of thyroid disease and thyroid cancer in both English and Spanish. The ATA website serves as the clinical resource for patients and the public who look for reliable information on the Internet. Every fifth year, the American Thyroid Association joins with the Latin American Thyroid Society, the European Thyroid Association, and the Asia and Oceania Thyroid Association to cosponsor the International Thyroid Congress (ITC).
The post American Thyroid Association: Dr. Elizabeth Pearce to Lead 2018-2019 Board of Directors appeared first on American Thyroid Association.
Recurrent dislocation of the temporomandibular joint (TMJ) is rare. It is distinct from acute or chronic dislocation and is associated with considerable morbidity and deterioration in quality of life. To formulate a practical surgical treatment algorithm, we retrospectively reviewed the management and long-term outcomes of 14 patients who presented to a single hospital department over a period of six years (2010–2016), and collected data on demographics, clinical features, operation, and outcome.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2JG9M71
We read the article by Pabst et al1 with interest. Morbidity at the donor site of radial forearm flaps (RFF) has been the subject of much discussion, and we would like to describe a direct comparison of two techniques of closure in a single patient (Taylor et al. Radial forearm flap donor sites − A direct comparison of local hatchet flap closure versus split thickness skin grafting in a single patient. Presented at the British Association of Head and Neck Oncologists Annual Scientific Meeting, London, 2018).
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DoOoCK
Recurrent dislocation of the temporomandibular joint (TMJ) is rare. It is distinct from acute or chronic dislocation and is associated with considerable morbidity and deterioration in quality of life. To formulate a practical surgical treatment algorithm, we retrospectively reviewed the management and long-term outcomes of 14 patients who presented to a single hospital department over a period of six years (2010–2016), and collected data on demographics, clinical features, operation, and outcome.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2JG9M71
We read the article by Pabst et al1 with interest. Morbidity at the donor site of radial forearm flaps (RFF) has been the subject of much discussion, and we would like to describe a direct comparison of two techniques of closure in a single patient (Taylor et al. Radial forearm flap donor sites − A direct comparison of local hatchet flap closure versus split thickness skin grafting in a single patient. Presented at the British Association of Head and Neck Oncologists Annual Scientific Meeting, London, 2018).
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DoOoCK
| NCRI: Highlights from the Annual Conference MedPage TodayFull coverage |
| Timely care key to improving survival rates and racial disparities EurekAlert (press release)Full coverage |
| Timely care key to improving survival rates and racial disparities EurekAlert (press release)Full coverage |
The Laryngoscope, EarlyView. (Source: The Laryngoscope)
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The Laryngoscope, EarlyView. (Source: The Laryngoscope)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OoLm2p
Neuroimmune interaction has long been discussed in the pathogenesis of allergic airway diseases, such as allergic asthma. Mediators released during inflammation can alter the function of both sensory and parasympathetic neurons innervating the airways. Evidence has been provided that the inflammatory response can be altered by various mediators that are released by sensory and parasympathetic neurons and vice versa. Our aim is to demonstrate recent developments in the reciprocal neuroimmune interaction and to include, if available, data from in vivo and clinical studies. (Source: Journal of Allergy and Clinical Immunology)
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(Source: Journal of Allergy and Clinical Immunology)
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With regard to the Letter to the Editor published in the July 2018 issue entitled "Mast cell–derived plasminogen activator inhibitor type 1 promotes airway inflammation and remodeling in a murine model of asthma" (J Allergy Clin Immunol 2018;142:294-7.e5), the authors have informed the Journal that one of the authors, Seung-Jae Hong, was mistakenly listed as being at the Di vision of Allergy-Immunology, James A. Haley Veterans' Hospital, Tampa, Fla. His institution is actually the Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, Korea, which was listed as "d" in the legend. (Source: Journal of Allergy and Clinical Immunology)
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Cough is an essential defensive behavior for maintaining airway patency and to protect the lungs from potentially harmful agents. However, inflammatory pathologies can sensitize and activate the neural pathways regulating cough, leading to excessive and nonproductive coughing that serves little protective utility. Problematic cough continues to be one of the most common reasons for seeking medical advice, yet for many patients, it can be refractory to disease-specific treatments and currently available antitussive therapies. (Source: Journal of Allergy and Clinical Immunology)
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