Nature ’s Path Foods Recalls A Specific Production Run Of Envirokidz Choco Chimps, Gorilla Munch And Jungle Munch Cereals Due To Undeclared Gluten

Today, Nature 's Path Foods announced a voluntary recall of a specific production run of EnviroKidz Choco Chimps, Gorilla Munch and Jungle Munch cereals for they may contain undeclared gluten (wheat and barley). People who have a wheat allergy, celiac disease or sensitivity to gluten and wheat should not consum e the cereals with the BEST BEFORE DATE listed below due to potential adverse health effects. Nature's Path is also removing any affected cereals from customer store shelves and warehouses. (Source: Food and Drug Administration)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEkcLS

Nature ’s Path Foods Recalls A Specific Production Run Of Envirokidz Choco Chimps, Gorilla Munch And Jungle Munch Cereals Due To Undeclared Gluten

Today, Nature 's Path Foods announced a voluntary recall of a specific production run of EnviroKidz Choco Chimps, Gorilla Munch and Jungle Munch cereals for they may contain undeclared gluten (wheat and barley). People who have a wheat allergy, celiac disease or sensitivity to gluten and wheat should not consum e the cereals with the BEST BEFORE DATE listed below due to potential adverse health effects. Nature's Path is also removing any affected cereals from customer store shelves and warehouses. (Source: Food and Drug Administration)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEkcLS

Nature ’s Path Foods Recalls A Specific Production Run Of Envirokidz Choco Chimps, Gorilla Munch And Jungle Munch Cereals Due To Undeclared Gluten

Today, Nature 's Path Foods announced a voluntary recall of a specific production run of EnviroKidz Choco Chimps, Gorilla Munch and Jungle Munch cereals for they may contain undeclared gluten (wheat and barley). People who have a wheat allergy, celiac disease or sensitivity to gluten and wheat should not consum e the cereals with the BEST BEFORE DATE listed below due to potential adverse health effects. Nature's Path is also removing any affected cereals from customer store shelves and warehouses. (Source: Food and Drug Administration)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEkcLS

Nature ’s Path Foods Recalls A Specific Production Run Of Envirokidz Choco Chimps, Gorilla Munch And Jungle Munch Cereals Due To Undeclared Gluten

Today, Nature 's Path Foods announced a voluntary recall of a specific production run of EnviroKidz Choco Chimps, Gorilla Munch and Jungle Munch cereals for they may contain undeclared gluten (wheat and barley). People who have a wheat allergy, celiac disease or sensitivity to gluten and wheat should not consum e the cereals with the BEST BEFORE DATE listed below due to potential adverse health effects. Nature's Path is also removing any affected cereals from customer store shelves and warehouses. (Source: Food and Drug Administration)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEkcLS

Researchers find genetic vulnerability to menthol cigarette use

(NIH/National Institute on Deafness and Other Communication Disorders) A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive. The variant of the MRGPRX4 gene is five to eight times more frequent among smokers who use menthol cigarettes than other smokers. The multi-ethnic study is the first to look across all genes to identify genetic vulnerability to menthol cigarettes. (Source: EurekAlert! - Medicine and Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2STmzK7

Edmonton's deaf arts festival makes some noise

A deaf actor and playwright based in Edmonton, Chris Dodd is passionate about the arts but often leaves the theatre feeling underwhelmed, disconnected. (Source: CBC | Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IcrfqE

Researchers find genetic vulnerability to menthol cigarette use

(NIH/National Institute on Deafness and Other Communication Disorders) A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive. The variant of the MRGPRX4 gene is five to eight times more frequent among smokers who use menthol cigarettes than other smokers. The multi-ethnic study is the first to look across all genes to identify genetic vulnerability to menthol cigarettes. (Source: EurekAlert! - Medicine and Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2STmzK7

TBX1 Functions as a Tumor Suppressor in Thyroid Cancer Through Inhibiting the Activities of the PI3K/AKT and MAPK/ERK Pathways

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SHApQz

TBX1 Functions as a Tumor Suppressor in Thyroid Cancer Through Inhibiting the Activities of the PI3K/AKT and MAPK/ERK Pathways

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SHApQz

Edmonton's deaf arts festival makes some noise

A deaf actor and playwright based in Edmonton, Chris Dodd is passionate about the arts but often leaves the theatre feeling underwhelmed, disconnected. (Source: CBC | Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IcrfqE

Researchers find genetic vulnerability to menthol cigarette use

(NIH/National Institute on Deafness and Other Communication Disorders) A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive. The variant of the MRGPRX4 gene is five to eight times more frequent among smokers who use menthol cigarettes than other smokers. The multi-ethnic study is the first to look across all genes to identify genetic vulnerability to menthol cigarettes. (Source: EurekAlert! - Medicine and Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2STmzK7

Edmonton's deaf arts festival makes some noise

A deaf actor and playwright based in Edmonton, Chris Dodd is passionate about the arts but often leaves the theatre feeling underwhelmed, disconnected. (Source: CBC | Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IcrfqE

TBX1 Functions as a Tumor Suppressor in Thyroid Cancer Through Inhibiting the Activities of the PI3K/AKT and MAPK/ERK Pathways

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLFsbB

TBX1 Functions as a Tumor Suppressor in Thyroid Cancer Through Inhibiting the Activities of the PI3K/AKT and MAPK/ERK Pathways

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLFsbB

TBX1 Functions as a Tumor Suppressor in Thyroid Cancer Through Inhibiting the Activities of the PI3K/AKT and MAPK/ERK Pathways

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLFsbB

TBX1 Functions as a Tumor Suppressor in Thyroid Cancer Through Inhibiting the Activities of the PI3K/AKT and MAPK/ERK Pathways

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLFsbB

Brazilian Scale of Hearing and Language Development: Normality Curve for Infants and Children from 0 to 24 Months Old with Normal Hearing

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1675189

Introduction Cochlear implants are currently the most effective technological resource to facilitate access to the hearing world for deaf people. Their use, especially when implanted early in children, reduces the impact of deafness on hearing as well as on the development of spoken language. Objective To validate the first part of the Brazilian Scale of Hearing and Language Development (EDAL-1, in the Portuguese acronym) and to establish the normal curve in infants and children aged between 0 and 24 months old with normal hearing. Method This is an experimental study of a descriptive nature, conducted with 92 infants and children with normal hearing. Every infant/child was evaluated audiologically, and the EDAL-1 was applied to their parents. The responses were categorized by applying the EDAL-1 every 3 months for each child. Results The EDAL-1 was shown to be easily applied by the researcher and easily understood by the parents. It was possible to classify the sample every 3 months and describe the results. The average of the responses found in terms of scores for each age category shows an increasing scale following the evolution of the chronological age: 3 months—34.23 points; 6 months—54.68 points; 9 months—73 points; 12 months—82.5 points; 15 months—87 points; 18 months—91 points; 21 months—92.5 points, and 24 months—95.83 points. Conclusion The normal curve for EDAL-1 was successfully established. The averages can be considered as the standard protocol for normality, serving as a reference for comparison with other populations.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tmtKfA

Bilateral Simultaneous Endoscopic Dacryocystorhinostomy: Outcome and Impact on the Quality of Life of the Patients

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1675394

Introduction Bilateral simultaneous endoscopic dacryocystorhinostomy (endo-DCR) has received little attention in the literature, thus many surgeons continue to address bilateral nasolacrimal duct obstruction at two stages, rather than in the same setting. Objective To evaluate the feasibility and the outcome of simultaneous bilateral Endo-DCR and its impact on the quality of life of the patients. Methods We have conducted a retrospective analysis of patients who underwent bilateral simultaneous endo-DCR between March 2013 and February 2017 at our tertiary care institution. The reviewed data included clinical presentation; operative details; success rate; pre and postoperative evaluation of the symptoms of the patients, using the Nasolacrimal Duct Obstruction Symptom Score Questionnaire; satisfaction of the patients, and improvement in the quality of life, assessed by the Glasgow Benefit Inventory (GBI) questionnaire. Results Out of 128 cases in which endo-DCRs were performed, 13 were bilateral (26 sides). Postoperative success was documented in 24 of the 26 sides (92.3%), with a mean follow-up duration of 16.2 months. The two failed sides were reported in the same case. The preoperative symptom score ranged between 12 and 80 (mean ± standard deviation [SD]: 38.23 ± 15.7). The postoperative symptom score was significantly lower (mean ± SD: 5.4 ± 12.9). The success rates in unilateral and bilateral cases were comparable, with no statistically significant difference. A notable improvement in the quality of life of the patients was also reported, with a mean GBI score of 81.38 ± 12.37. Conclusion Our results support that a simultaneous bilateral endo-DCR is a safe procedure that offers a high success rate, spares the patient from the stress of a second surgery, provides the patient with a bilateral resolution of the symptoms, and confers an immediate improvement in the quality of life of the patients.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GH3EvP

Particularities and Clinical Applicability of Saccharin Transit Time Test

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1676116

Introduction The importance of mucociliary clearance (MCC) for the respiratory system homeostasis is clear. Therefore, evaluating this defense mechanism is fundamental in scientific research and in the clinical practice of pulmonology and of associated areas. However, MCC evaluation has not been so usual due to the complexity of methods that use radiolabeled particles. Nevertheless, as an interesting alternative, there is the saccharin transit time (STT) test. This method is reproducible, simple to perform, noninvasive, does not demand high costs, and has been widely used in studies of nasal MCC. Although the STT test is widely used, there is still lack of a detailed description of its realization. Objective The present literature review aims to provide basic information related to the STT test and to present the findings of the previous studies that used this method, discussing variations in its execution, possible influences on the obtained results and limitations of the method, as well as to relate our experience with the use of STT in researches. Data Synthesis There are several factors that can alter the results obtained from STT tests, which would raise difficulties with proper interpretation and with the discussion of the results among different studies. Conclusions Saccharin transit time is a widely used method for the evaluation of nasal MCC, and therefore, the standardization related to the previous and concurrent to test orientations, and also its execution, become essential to improve its accuracy, and allow comparisons among different studies.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tmtEVg

Menière's Disease and Disorders of the Carbohydrate Metabolism Involving the Inner Ear

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1673698

Introduction Menière's disease was described in 1861, but there are still uncertainties regarding its pathophysiology and treatment. Endolymphatic hydrops is recognized as a fundamental pathological characteristic of the disease, as a result of an inadequate absorption of the endolymph. A milder type of endolymphatic hydrops results from an altered chemical composition of the endolymph, due to disorders of the carbohydrate metabolism. Objective To describe the association of both types of hydrops in patients with Menière disease. Methods This was a retrospective study of 98 patients with Menière's disease, 62 of whom also presented disorders of the carbohydrate metabolism, and 5 patients with delayed endolymphatic hydrops, 2 of whom also presented disorders of the carbohydrate metabolism. Results The follow-up of these patients showed that the correction of the metabolic disorders may help in the clinical treatment of Menière's disease and of delayed endolymphatic hydrops, but this does not happen in the more severe types of the diseases. Conclusion Patients with Menière's disease may present simultaneous disorders of the carbohydrate metabolism, affecting the inner ear. The correction of these disorders helps the clinical treatment but does not preclude the progression of the more severe cases of Menière disease.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GNmjpx

Quality of Life Parameters should be Included in the Preoperative Informed Consent in Patients with Chronic Rhinosinusitis Scheduled for Functional Endoscopic Sinus Surgery

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1676313

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tmlGeX

Facial Plastic Surgery Faculty Turnover: Survey of Academic Facial Plastic Surgeons and Department Chairs

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1675188

Introduction The turnover and inability to consistently retain academic facial plastic surgeons is an issue that many academic departments of otolaryngology face. In addition to the financial costs of staff turnover and gaps in patient care, insufficient exposure of residents to key surgical procedures is a significant problem for residency programs. Objective To identify the most important reasons that lead faculty members to leave an academic facial plastic surgery (FPS) practice as well as features that may be associated with retention of FPS faculty. Methods Members of the American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS) and the Association of Academic Departments of Otolaryngology (AADO) were administered an anonymous, online survey. For both groups, we evaluated demographic factors, reasons for choosing academic careers, contributors to faculty turnover, as well as strategies for retention. The frequency of the responses was analyzed. Results A total of 11.3% (135/1,200) of facial plastic surgery faculty responded to the faculty survey, with 59.1% (68/115) of current, academic surgeons participating, and a total of 16.7% (20/120) of department chairs responded to the chairs' survey. If a faculty member had left/was to leave, more control over practice was the most common reason between the two respondent groups. Of the five most important ways to increase faculty retention, more control over practice was the number one reason. Conclusion Chairs and facial plastic surgery faculty should strive to agree upon the amount of control over the academic practice to lead to higher retention, better patient care, and continued resident education.
[...]

Thieme Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GM4ZkM

Comment on: “Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?”

We would like to comment on the interesting article titled, "Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?," by Sawatari et al.1

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLsLxj

Could Your IoT Device Put Patients at Risk?

The Internet of Things is driving incredible innovation in healthcare. âAlmost any new innovative medical device is currently designed as a part of broader interconnected system,â Rami Muleys, head of application security business development at Positive Technologies, told MD+DI. âThe main value of IoT is the convergence between different systems and the ability to exchange data between every device â from an insulin pump to a hospital bed.â Healthcare is consequently âa constantly changing landscape, especially since more and more companies are finding new niches with their existing non-medical devices,â said Muleys. âA good example would be fitne...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Nd8h1W

Immunotherapy Lurches Forward in Prostate Cancer

(MedPage Today) -- Combination trials in mCRPC yield responses in immunologically " cold " tumor (Source: MedPage Today Hematology/Oncology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SSk8rr

Brazilian Scale of Hearing and Language Development: Normality Curve for Infants and Children from 0 to 24 Months Old with Normal Hearing

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1675189

Introduction Cochlear implants are currently the most effective technological resource to facilitate access to the hearing world for deaf people. Their use, especially when implanted early in children, reduces the impact of deafness on hearing as well as on the development of spoken language. Objective To validate the first part of the Brazilian Scale of Hearing and Language Development (EDAL-1, in the Portuguese acronym) and to establish the normal curve in infants and children aged between 0 and 24 months old with normal hearing. Method This is an experimental study of a descriptive nature, conducted with 92 infants and children with normal hearing. Every infant/child was evaluated audiologically, and the EDAL-1 was applied to their parents. The responses were categorized by applying the EDAL-1 every 3 months for each child. Results The EDAL-1 was shown to be easily applied by the researcher and easily understood by the parents. It was possible to classify the sample every 3 months and describe the results. The average of the responses found in terms of scores for each age category shows an increasing scale following the evolution of the chronological age: 3 months—34.23 points; 6 months—54.68 points; 9 months—73 points; 12 months—82.5 points; 15 months—87 points; 18 months—91 points; 21 months—92.5 points, and 24 months—95.83 points. Conclusion The normal curve for EDAL-1 was successfully established. The averages can be considered as the standard protocol for normality, serving as a reference for comparison with other populations.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tmtKfA

Bilateral Simultaneous Endoscopic Dacryocystorhinostomy: Outcome and Impact on the Quality of Life of the Patients

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1675394

Introduction Bilateral simultaneous endoscopic dacryocystorhinostomy (endo-DCR) has received little attention in the literature, thus many surgeons continue to address bilateral nasolacrimal duct obstruction at two stages, rather than in the same setting. Objective To evaluate the feasibility and the outcome of simultaneous bilateral Endo-DCR and its impact on the quality of life of the patients. Methods We have conducted a retrospective analysis of patients who underwent bilateral simultaneous endo-DCR between March 2013 and February 2017 at our tertiary care institution. The reviewed data included clinical presentation; operative details; success rate; pre and postoperative evaluation of the symptoms of the patients, using the Nasolacrimal Duct Obstruction Symptom Score Questionnaire; satisfaction of the patients, and improvement in the quality of life, assessed by the Glasgow Benefit Inventory (GBI) questionnaire. Results Out of 128 cases in which endo-DCRs were performed, 13 were bilateral (26 sides). Postoperative success was documented in 24 of the 26 sides (92.3%), with a mean follow-up duration of 16.2 months. The two failed sides were reported in the same case. The preoperative symptom score ranged between 12 and 80 (mean ± standard deviation [SD]: 38.23 ± 15.7). The postoperative symptom score was significantly lower (mean ± SD: 5.4 ± 12.9). The success rates in unilateral and bilateral cases were comparable, with no statistically significant difference. A notable improvement in the quality of life of the patients was also reported, with a mean GBI score of 81.38 ± 12.37. Conclusion Our results support that a simultaneous bilateral endo-DCR is a safe procedure that offers a high success rate, spares the patient from the stress of a second surgery, provides the patient with a bilateral resolution of the symptoms, and confers an immediate improvement in the quality of life of the patients.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GH3EvP

Particularities and Clinical Applicability of Saccharin Transit Time Test

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1676116

Introduction The importance of mucociliary clearance (MCC) for the respiratory system homeostasis is clear. Therefore, evaluating this defense mechanism is fundamental in scientific research and in the clinical practice of pulmonology and of associated areas. However, MCC evaluation has not been so usual due to the complexity of methods that use radiolabeled particles. Nevertheless, as an interesting alternative, there is the saccharin transit time (STT) test. This method is reproducible, simple to perform, noninvasive, does not demand high costs, and has been widely used in studies of nasal MCC. Although the STT test is widely used, there is still lack of a detailed description of its realization. Objective The present literature review aims to provide basic information related to the STT test and to present the findings of the previous studies that used this method, discussing variations in its execution, possible influences on the obtained results and limitations of the method, as well as to relate our experience with the use of STT in researches. Data Synthesis There are several factors that can alter the results obtained from STT tests, which would raise difficulties with proper interpretation and with the discussion of the results among different studies. Conclusions Saccharin transit time is a widely used method for the evaluation of nasal MCC, and therefore, the standardization related to the previous and concurrent to test orientations, and also its execution, become essential to improve its accuracy, and allow comparisons among different studies.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tmtEVg

Menière's Disease and Disorders of the Carbohydrate Metabolism Involving the Inner Ear

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1673698

Introduction Menière's disease was described in 1861, but there are still uncertainties regarding its pathophysiology and treatment. Endolymphatic hydrops is recognized as a fundamental pathological characteristic of the disease, as a result of an inadequate absorption of the endolymph. A milder type of endolymphatic hydrops results from an altered chemical composition of the endolymph, due to disorders of the carbohydrate metabolism. Objective To describe the association of both types of hydrops in patients with Menière disease. Methods This was a retrospective study of 98 patients with Menière's disease, 62 of whom also presented disorders of the carbohydrate metabolism, and 5 patients with delayed endolymphatic hydrops, 2 of whom also presented disorders of the carbohydrate metabolism. Results The follow-up of these patients showed that the correction of the metabolic disorders may help in the clinical treatment of Menière's disease and of delayed endolymphatic hydrops, but this does not happen in the more severe types of the diseases. Conclusion Patients with Menière's disease may present simultaneous disorders of the carbohydrate metabolism, affecting the inner ear. The correction of these disorders helps the clinical treatment but does not preclude the progression of the more severe cases of Menière disease.
[...]

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GNmjpx

Quality of Life Parameters should be Included in the Preoperative Informed Consent in Patients with Chronic Rhinosinusitis Scheduled for Functional Endoscopic Sinus Surgery

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1676313

Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tmlGeX

Facial Plastic Surgery Faculty Turnover: Survey of Academic Facial Plastic Surgeons and Department Chairs

Int Arch Otorhinolaryngol
DOI: 10.1055/s-0038-1675188

Introduction The turnover and inability to consistently retain academic facial plastic surgeons is an issue that many academic departments of otolaryngology face. In addition to the financial costs of staff turnover and gaps in patient care, insufficient exposure of residents to key surgical procedures is a significant problem for residency programs. Objective To identify the most important reasons that lead faculty members to leave an academic facial plastic surgery (FPS) practice as well as features that may be associated with retention of FPS faculty. Methods Members of the American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS) and the Association of Academic Departments of Otolaryngology (AADO) were administered an anonymous, online survey. For both groups, we evaluated demographic factors, reasons for choosing academic careers, contributors to faculty turnover, as well as strategies for retention. The frequency of the responses was analyzed. Results A total of 11.3% (135/1,200) of facial plastic surgery faculty responded to the faculty survey, with 59.1% (68/115) of current, academic surgeons participating, and a total of 16.7% (20/120) of department chairs responded to the chairs' survey. If a faculty member had left/was to leave, more control over practice was the most common reason between the two respondent groups. Of the five most important ways to increase faculty retention, more control over practice was the number one reason. Conclusion Chairs and facial plastic surgery faculty should strive to agree upon the amount of control over the academic practice to lead to higher retention, better patient care, and continued resident education.
[...]

Thieme Publicações Ltda Rio de Janeiro, Brazil

Article in Thieme eJournals:
Table of contents  |  Abstract  |  open access Full text

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GM4ZkM

Comment on: “Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?”

We would like to comment on the interesting article titled, "Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?," by Sawatari et al.1

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLsLxj

Could Your IoT Device Put Patients at Risk?

The Internet of Things is driving incredible innovation in healthcare. âAlmost any new innovative medical device is currently designed as a part of broader interconnected system,â Rami Muleys, head of application security business development at Positive Technologies, told MD+DI. âThe main value of IoT is the convergence between different systems and the ability to exchange data between every device â from an insulin pump to a hospital bed.â Healthcare is consequently âa constantly changing landscape, especially since more and more companies are finding new niches with their existing non-medical devices,â said Muleys. âA good example would be fitne...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Nd8h1W

Immunotherapy Lurches Forward in Prostate Cancer

(MedPage Today) -- Combination trials in mCRPC yield responses in immunologically " cold " tumor (Source: MedPage Today Hematology/Oncology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SSk8rr

Could Your IoT Device Put Patients at Risk?

The Internet of Things is driving incredible innovation in healthcare. âAlmost any new innovative medical device is currently designed as a part of broader interconnected system,â Rami Muleys, head of application security business development at Positive Technologies, told MD+DI. âThe main value of IoT is the convergence between different systems and the ability to exchange data between every device â from an insulin pump to a hospital bed.â Healthcare is consequently âa constantly changing landscape, especially since more and more companies are finding new niches with their existing non-medical devices,â said Muleys. âA good example would be fitne...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Nd8h1W

Immunotherapy Lurches Forward in Prostate Cancer

(MedPage Today) -- Combination trials in mCRPC yield responses in immunologically " cold " tumor (Source: MedPage Today Hematology/Oncology)

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Could Your IoT Device Put Patients at Risk?

The Internet of Things is driving incredible innovation in healthcare. âAlmost any new innovative medical device is currently designed as a part of broader interconnected system,â Rami Muleys, head of application security business development at Positive Technologies, told MD+DI. âThe main value of IoT is the convergence between different systems and the ability to exchange data between every device â from an insulin pump to a hospital bed.â Healthcare is consequently âa constantly changing landscape, especially since more and more companies are finding new niches with their existing non-medical devices,â said Muleys. âA good example would be fitne...

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Nd8h1W

Immunotherapy Lurches Forward in Prostate Cancer

(MedPage Today) -- Combination trials in mCRPC yield responses in immunologically " cold " tumor (Source: MedPage Today Hematology/Oncology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SSk8rr

Comment on: “Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?”

We would like to comment on the interesting article titled, "Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?," by Sawatari et al.1

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Comment on: “Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?”

We would like to comment on the interesting article titled, "Does Accurate Positioning of the Temporomandibular Joint Titanium Condylar Prosthesis Prevent Complications?," by Sawatari et al.1

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLsLxj

Reconstruction of the temporomandibular joint: a comparison between prefabricated and customized alloplastic prosthetic total joint systems

The implantation of an alloplastic total temporomandibular joint (TMJ) prosthesis is an innovative approach for the treatment of end-stage TMJ disorders. Two types of system exist: prefabricated (stock) and customized computer-aided design/computer-aided manufacturing (CAD/CAM) devices. A clinical study was performed to evaluate the effectiveness of these two designs. Twenty-eight patients treated between 2015 and 2017 were included and assigned to two groups: stock prostheses (group 1) and customized CAD/CAM prostheses (group 2). (Source: International Journal of Oral and Maxillofacial Surgery)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DJMVF3

Influence of mandibular setback surgery on three-dimensional pharyngeal airway changes

The aim of this study was to investigate the factors influencing three-dimensional changes in pharyngeal airway space after mandibular setback surgery. Airway changes in 48 skeletal class III patients who had undergone mandibular setback surgery alone (n=25, group 1) or with maxillary surgery (n=23, group 2) were analyzed. Linear parameters, cross-sectional area, and volumes of the pharyngeal airway were evaluated before (T0), immediately after (T1), and 1year after surgery (T2) by cone beam computed tomography. (Source: International Journal of Oral and Maxillofacial Surgery)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SAzb9Z

Locally advanced mammary analogue secretory carcinoma of the parotid gland

Mammary analogue secretory carcinoma (MASC) has recently been recognized as a salivary gland tumour that is characterized by the ETV6 –NTRK3 fusion gene. A case of locally advanced MASC of the parotid gland in a 67-year-old man is presented here. The patient visited the hospital due to a large right infra-auricular mass, which had been enlarging gradually over a period of 2years. Contrast-enhanced computed tomography (CT) demons trated a multilocular mass, 75×63mm in size, containing a fluid component with non-uniform contrast effects in the interior portion. (Source: International Journal of Oral and Maxillofacial Surgery)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DTptFx

Influence of mandibular setback surgery on three-dimensional pharyngeal airway changes

The aim of this study was to investigate the factors influencing three-dimensional changes in pharyngeal airway space after mandibular setback surgery. Airway changes in 48 skeletal class III patients who had undergone mandibular setback surgery alone (n=25, group 1) or with maxillary surgery (n=23, group 2) were analyzed. Linear parameters, cross-sectional area, and volumes of the pharyngeal airway were evaluated before (T0), immediately after (T1), and 1year after surgery (T2) by cone beam computed tomography. (Source: International Journal of Oral and Maxillofacial Surgery)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SAzb9Z

Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV

Condition:   HIV-1-infection Interventions:   Drug: Saline;   Drug: Lefitolimod;   Drug: 3BNC117 and 10-1074 Sponsors:   University of Aarhus;   Aalborg Universitetshospital;   Odense University Hospital;   Rigshospitalet, Denmark;   Hvidovre University Hospital;   The Peter Doherty Institute for Infection and Immunity;   University of Utah Not yet recruiting (Source: ClinicalTrials.gov)

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Combination Therapy With VRC-HIVMAB060-00-AB (VRC01) and 10-1074 in HIV-Infected Individuals Undergoing Sequential Treatment Interruptions

Condition:   HIV Interventions:   Biological: VRC-HIVMAB060-00-AB (VRC01);   Biological: 10-1074;   Biological: Normal Saline Placebo Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BDud1D

Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet

Conditions:   Intervention;   Food Allergy;   Food Preferences;   Food Intolerance;   Diet Habit;   Diet Modification Intervention:   Behavioral: Multicomponent intervention Sponsors:   University Rovira i Virgili;   Diputació de Tarragona Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TMyOWa

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Conditions:   Pulmonary Invasive Mold Infections;   Pulmonary Invasive Aspergillosis Intervention:   Diagnostic Test: Non-Invasive Testing for PIMI Sponsors:   Duke University;   Children's Hospital of Philadelphia;   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

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Retrospective Chart Review of Candida Fungemia

Condition:   Candida Intervention:   Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Active, not recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TNByCQ

Safety Study of Hepatitis E Vaccine (HEV239) in Healthy US Adult Population

Conditions:   Hepatitis E;   Immunisation Interventions:   Biological: HEV 239;   Other: Placebo Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TNBuD6

Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV

Condition:   HIV-1-infection Interventions:   Drug: Saline;   Drug: Lefitolimod;   Drug: 3BNC117 and 10-1074 Sponsors:   University of Aarhus;   Aalborg Universitetshospital;   Odense University Hospital;   Rigshospitalet, Denmark;   Hvidovre University Hospital;   The Peter Doherty Institute for Infection and Immunity;   University of Utah Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TNBGCk

Combination Therapy With VRC-HIVMAB060-00-AB (VRC01) and 10-1074 in HIV-Infected Individuals Undergoing Sequential Treatment Interruptions

Condition:   HIV Interventions:   Biological: VRC-HIVMAB060-00-AB (VRC01);   Biological: 10-1074;   Biological: Normal Saline Placebo Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BDud1D

Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet

Conditions:   Intervention;   Food Allergy;   Food Preferences;   Food Intolerance;   Diet Habit;   Diet Modification Intervention:   Behavioral: Multicomponent intervention Sponsors:   University Rovira i Virgili;   Diputació de Tarragona Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TMyOWa

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Conditions:   Pulmonary Invasive Mold Infections;   Pulmonary Invasive Aspergillosis Intervention:   Diagnostic Test: Non-Invasive Testing for PIMI Sponsors:   Duke University;   Children's Hospital of Philadelphia;   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BHfEKl

Retrospective Chart Review of Candida Fungemia

Condition:   Candida Intervention:   Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Active, not recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TNByCQ

Allergy UK Research and Development Nurse Project

Condition:   Allergy Intervention:   Other: Nurse Led Allergy Clinic Sponsors:   University of Edinburgh;   Allergy UK Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BxWTZR

Safety Study of Hepatitis E Vaccine (HEV239) in Healthy US Adult Population

Conditions:   Hepatitis E;   Immunisation Interventions:   Biological: HEV 239;   Other: Placebo Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TNBuD6

Sports-Related Concussion: Neurometabolic Aspects

Semin Speech Lang DOI: 10.1055/s-0039-1679887Concussion is a transitory brain injury resulting from a blow to the head. Concussion is considered a mild traumatic brain injury (mTBI), which is self-limited. Repetitive mTBI has been associated with chronic, progressive neurological damage. Extreme biochemical changes occur in neuron cells as a result of mTBI. These metabolic disturbances may reflect the symptoms observed in patients who had suffered concussions. However, it has been difficult to correlate clinical signs and symptoms. Currently, there are no laboratory tests to diagnose concussion, though several biomarkers are being investigated. Further studies are needed to elucidate the biochemical details of the metabolic cascade and the associated time frame, which will help determine w...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Igz7rb

Sports-Related Concussion: Neurometabolic Aspects

Semin Speech Lang DOI: 10.1055/s-0039-1679887Concussion is a transitory brain injury resulting from a blow to the head. Concussion is considered a mild traumatic brain injury (mTBI), which is self-limited. Repetitive mTBI has been associated with chronic, progressive neurological damage. Extreme biochemical changes occur in neuron cells as a result of mTBI. These metabolic disturbances may reflect the symptoms observed in patients who had suffered concussions. However, it has been difficult to correlate clinical signs and symptoms. Currently, there are no laboratory tests to diagnose concussion, though several biomarkers are being investigated. Further studies are needed to elucidate the biochemical details of the metabolic cascade and the associated time frame, which will help determine w...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Igz7rb

Reconstruction of the temporomandibular joint: a comparison between prefabricated and customized alloplastic prosthetic total joint systems

The implantation of an alloplastic total temporomandibular joint (TMJ) prosthesis is an innovative approach for the treatment of end-stage TMJ disorders. Two types of system exist: prefabricated (stock) and customized computer-aided design/computer-aided manufacturing (CAD/CAM) devices. A clinical study was performed to evaluate the effectiveness of these two designs. Twenty-eight patients treated between 2015 and 2017 were included and assigned to two groups: stock prostheses (group 1) and customized CAD/CAM prostheses (group 2).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WYIw9U

Locally advanced mammary analogue secretory carcinoma of the parotid gland

Mammary analogue secretory carcinoma (MASC) has recently been recognized as a salivary gland tumour that is characterized by the ETV6–NTRK3 fusion gene. A case of locally advanced MASC of the parotid gland in a 67-year-old man is presented here. The patient visited the hospital due to a large right infra-auricular mass, which had been enlarging gradually over a period of 2years. Contrast-enhanced computed tomography (CT) demonstrated a multilocular mass, 75×63mm in size, containing a fluid component with non-uniform contrast effects in the interior portion.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2S82Py6

Accuracy of custom-fitted temporomandibular joint alloplastic reconstruction and virtual surgical planning

The purpose of this study was to evaluate the accuracy of temporomandibular joint (TMJ) custom-made replacements by means of virtual surgical planning.The authors review 11 TMJ custom-made prostheses made of both mandibular and fossa components. Surgeries were virtually planned and patient-specific devices were designed together with surgical cutting and positional guides. Three-dimensional models for both preoperative planning and postoperative computed tomography scans were generated and overlapped in order to evaluate differences in measurements.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2XeP4l4

Influence of mandibular setback surgery on three-dimensional pharyngeal airway changes

The aim of this study was to investigate the factors influencing three-dimensional changes in pharyngeal airway space after mandibular setback surgery. Airway changes in 48 skeletal class III patients who had undergone mandibular setback surgery alone (n=25, group 1) or with maxillary surgery (n=23, group 2) were analyzed. Linear parameters, cross-sectional area, and volumes of the pharyngeal airway were evaluated before (T0), immediately after (T1), and 1year after surgery (T2) by cone beam computed tomography.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2S6D5SG

Reconstruction of the temporomandibular joint: a comparison between prefabricated and customized alloplastic prosthetic total joint systems

The implantation of an alloplastic total temporomandibular joint (TMJ) prosthesis is an innovative approach for the treatment of end-stage TMJ disorders. Two types of system exist: prefabricated (stock) and customized computer-aided design/computer-aided manufacturing (CAD/CAM) devices. A clinical study was performed to evaluate the effectiveness of these two designs. Twenty-eight patients treated between 2015 and 2017 were included and assigned to two groups: stock prostheses (group 1) and customized CAD/CAM prostheses (group 2).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WYIw9U

Locally advanced mammary analogue secretory carcinoma of the parotid gland

Mammary analogue secretory carcinoma (MASC) has recently been recognized as a salivary gland tumour that is characterized by the ETV6–NTRK3 fusion gene. A case of locally advanced MASC of the parotid gland in a 67-year-old man is presented here. The patient visited the hospital due to a large right infra-auricular mass, which had been enlarging gradually over a period of 2years. Contrast-enhanced computed tomography (CT) demonstrated a multilocular mass, 75×63mm in size, containing a fluid component with non-uniform contrast effects in the interior portion.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2S82Py6

Accuracy of custom-fitted temporomandibular joint alloplastic reconstruction and virtual surgical planning

The purpose of this study was to evaluate the accuracy of temporomandibular joint (TMJ) custom-made replacements by means of virtual surgical planning.The authors review 11 TMJ custom-made prostheses made of both mandibular and fossa components. Surgeries were virtually planned and patient-specific devices were designed together with surgical cutting and positional guides. Three-dimensional models for both preoperative planning and postoperative computed tomography scans were generated and overlapped in order to evaluate differences in measurements.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2XeP4l4

Influence of mandibular setback surgery on three-dimensional pharyngeal airway changes

The aim of this study was to investigate the factors influencing three-dimensional changes in pharyngeal airway space after mandibular setback surgery. Airway changes in 48 skeletal class III patients who had undergone mandibular setback surgery alone (n=25, group 1) or with maxillary surgery (n=23, group 2) were analyzed. Linear parameters, cross-sectional area, and volumes of the pharyngeal airway were evaluated before (T0), immediately after (T1), and 1year after surgery (T2) by cone beam computed tomography.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2S6D5SG

Recurrent Strep Throat Linked to Aberrant Immune Responses Recurrent Strep Throat Linked to Aberrant Immune Responses

Several alterations in immune responses contribute to the risk of recurrent group A Streptococcus tonsillitis ("strep throat"), researchers report.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gt9wtm

Treg Cells Show Promise as Immunotherapy for Crohn's Disease Treg Cells Show Promise as Immunotherapy for Crohn's Disease

Crohn's disease (CD) symptoms may be reduced if an agonist of the retinoic acid receptor alpha (RARA) can be used to traffic T-regulatory (Treg) cells to inflamed intestinal tissues, researchers suggest.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IqtfLI

Mylan Launches Advair Generic at One-Third Price Mylan Launches Advair Generic at One-Third Price

Mylan NV on Tuesday priced its generic version of GlaxoSmithKline's blockbuster asthma treatment Advair 70 percent lower than the branded medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Iqtaro

Recurrent Strep Throat Linked to Aberrant Immune Responses Recurrent Strep Throat Linked to Aberrant Immune Responses

Several alterations in immune responses contribute to the risk of recurrent group A Streptococcus tonsillitis ("strep throat"), researchers report.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gt9wtm

Treg Cells Show Promise as Immunotherapy for Crohn's Disease Treg Cells Show Promise as Immunotherapy for Crohn's Disease

Crohn's disease (CD) symptoms may be reduced if an agonist of the retinoic acid receptor alpha (RARA) can be used to traffic T-regulatory (Treg) cells to inflamed intestinal tissues, researchers suggest.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IqtfLI

Sleep Boosts T-Cell Antiviral Potency Sleep Boosts T-Cell Antiviral Potency

It looks like your mother was right: when you've got a cold, sleep may be the best medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GtSQSd

Mylan Launches Advair Generic at One-Third Price Mylan Launches Advair Generic at One-Third Price

Mylan NV on Tuesday priced its generic version of GlaxoSmithKline's blockbuster asthma treatment Advair 70 percent lower than the branded medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Iqtaro

Penicillin and clindamycin associated anaphylaxis and serious cutaneous adverse reactions

The population-based incidence of penicillin- and clindamycin-associated anaphylaxis and serious cutaneous adverse reactions (SCARs) is uncertain.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2X6oYAp

Treatments of Cold Urticaria: A Systematic Review

Modern, second-generation H1-antihistamines at standard and up to fourfold dosages, as well as 150- and 300-mg dosages of omalizumab, are safe and effective in the treatment of cold urticaria.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2X250a6

Penicillin and clindamycin associated anaphylaxis and serious cutaneous adverse reactions

The population-based incidence of penicillin- and clindamycin-associated anaphylaxis and serious cutaneous adverse reactions (SCARs) is uncertain.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2X6oYAp

Adenoid cystic carcinoma with high-grade transformation forming spindle cell component of the submandibular gland

Adenoid cystic carcinoma (AdCC) with high-grade transformation (AdCC-HGT) is rare, and AdCC-HGT with spindle cell component is particularly rare. The patient was a 65-year-old man with a 5 cm sized swelling of the right submandibular gland. Submandibular sialoadenectomy was performed. Histopathological findings mainly showed conventional AdCC, and minorly showed two other components: (1) the pleomorphic component, a proliferation of atypical pleomorphic epithelial cells forming solid or small clusters and accompanied by necrosis; (2) the spindle cell component, containing atypical spindle cells invading the stroma.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DIFZI5

Adenoid cystic carcinoma with high-grade transformation forming spindle cell component of the submandibular gland

Adenoid cystic carcinoma (AdCC) with high-grade transformation (AdCC-HGT) is rare, and AdCC-HGT with spindle cell component is particularly rare. The patient was a 65-year-old man with a 5 cm sized swelling of the right submandibular gland. Submandibular sialoadenectomy was performed. Histopathological findings mainly showed conventional AdCC, and minorly showed two other components: (1) the pleomorphic component, a proliferation of atypical pleomorphic epithelial cells forming solid or small clusters and accompanied by necrosis; (2) the spindle cell component, containing atypical spindle cells invading the stroma.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DIFZI5

Combination of photodynamic therapy and antimicrobial compounds to treat skin and mucosal infections: a systematic review.

Photochem. Photobiol. Sci., 2019, Accepted Manuscript
DOI: 10.1039/C8PP00534F, Paper

Vanesa Pérez Laguna, Yolanda Gilaberte, Maria Isabel Millán-Lou, Montserrat Agut, Santi Nonell, Antonio Rezusta, Michael R Hamblin
Background: Antimicrobial photodynamic therapy (aPDT) is a growing approach to treat skin and mucosal infections. Despite its effectiveness, investigators have explored whether aPDT can be further combined with antibiotics and...
The content of this RSS Feed (c) The Royal Society of Chemistry

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://rsc.li/2V4mX6f

Combination of photodynamic therapy and antimicrobial compounds to treat skin and mucosal infections: a systematic review.

Photochem. Photobiol. Sci., 2019, Accepted Manuscript
DOI: 10.1039/C8PP00534F, Paper

Vanesa Pérez Laguna, Yolanda Gilaberte, Maria Isabel Millán-Lou, Montserrat Agut, Santi Nonell, Antonio Rezusta, Michael R Hamblin
Background: Antimicrobial photodynamic therapy (aPDT) is a growing approach to treat skin and mucosal infections. Despite its effectiveness, investigators have explored whether aPDT can be further combined with antibiotics and...
The content of this RSS Feed (c) The Royal Society of Chemistry

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://rsc.li/2V4mX6f

Recurrent Strep Throat Linked to Aberrant Immune Responses Recurrent Strep Throat Linked to Aberrant Immune Responses

Several alterations in immune responses contribute to the risk of recurrent group A Streptococcus tonsillitis ("strep throat"), researchers report.Reuters Health Information (Source: Medscape Allergy Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gt9wtm

Treg Cells Show Promise as Immunotherapy for Crohn's Disease Treg Cells Show Promise as Immunotherapy for Crohn's Disease

Crohn's disease (CD) symptoms may be reduced if an agonist of the retinoic acid receptor alpha (RARA) can be used to traffic T-regulatory (Treg) cells to inflamed intestinal tissues, researchers suggest.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IqtfLI

Mylan Launches Advair Generic at One-Third Price Mylan Launches Advair Generic at One-Third Price

Mylan NV on Tuesday priced its generic version of GlaxoSmithKline's blockbuster asthma treatment Advair 70 percent lower than the branded medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Iqtaro

Ask Well: Can You Get Over a Food Intolerance?

Foods most often associated with intolerances were chocolate, food additives, citrus fruits, fish, shellfish, milk, cheese, eggs and nuts. (Source: NYT Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gu17pd

Recurrent Strep Throat Linked to Aberrant Immune Responses Recurrent Strep Throat Linked to Aberrant Immune Responses

Several alterations in immune responses contribute to the risk of recurrent group A Streptococcus tonsillitis ("strep throat"), researchers report.Reuters Health Information (Source: Medscape Allergy Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gt9wtm

Treg Cells Show Promise as Immunotherapy for Crohn's Disease Treg Cells Show Promise as Immunotherapy for Crohn's Disease

Crohn's disease (CD) symptoms may be reduced if an agonist of the retinoic acid receptor alpha (RARA) can be used to traffic T-regulatory (Treg) cells to inflamed intestinal tissues, researchers suggest.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IqtfLI

Sleep Boosts T-Cell Antiviral Potency Sleep Boosts T-Cell Antiviral Potency

It looks like your mother was right: when you've got a cold, sleep may be the best medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GtSQSd

Mylan Launches Advair Generic at One-Third Price Mylan Launches Advair Generic at One-Third Price

Mylan NV on Tuesday priced its generic version of GlaxoSmithKline's blockbuster asthma treatment Advair 70 percent lower than the branded medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Iqtaro

Ask Well: Can You Get Over a Food Intolerance?

Foods most often associated with intolerances were chocolate, food additives, citrus fruits, fish, shellfish, milk, cheese, eggs and nuts. (Source: NYT Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gu17pd

Recurrent Strep Throat Linked to Aberrant Immune Responses Recurrent Strep Throat Linked to Aberrant Immune Responses

Several alterations in immune responses contribute to the risk of recurrent group A Streptococcus tonsillitis ("strep throat"), researchers report.Reuters Health Information (Source: Medscape Allergy Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gt9wtm

Treg Cells Show Promise as Immunotherapy for Crohn's Disease Treg Cells Show Promise as Immunotherapy for Crohn's Disease

Crohn's disease (CD) symptoms may be reduced if an agonist of the retinoic acid receptor alpha (RARA) can be used to traffic T-regulatory (Treg) cells to inflamed intestinal tissues, researchers suggest.Reuters Health Information (Source: Medscape Allergy Headlines)

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Sleep Boosts T-Cell Antiviral Potency Sleep Boosts T-Cell Antiviral Potency

It looks like your mother was right: when you've got a cold, sleep may be the best medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

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Mylan Launches Advair Generic at One-Third Price Mylan Launches Advair Generic at One-Third Price

Mylan NV on Tuesday priced its generic version of GlaxoSmithKline's blockbuster asthma treatment Advair 70 percent lower than the branded medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

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Ask Well: Can You Get Over a Food Intolerance?

Foods most often associated with intolerances were chocolate, food additives, citrus fruits, fish, shellfish, milk, cheese, eggs and nuts. (Source: NYT Health)

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Recurrent Strep Throat Linked to Aberrant Immune Responses Recurrent Strep Throat Linked to Aberrant Immune Responses

Several alterations in immune responses contribute to the risk of recurrent group A Streptococcus tonsillitis ("strep throat"), researchers report.Reuters Health Information (Source: Medscape Allergy Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gt9wtm

Treg Cells Show Promise as Immunotherapy for Crohn's Disease Treg Cells Show Promise as Immunotherapy for Crohn's Disease

Crohn's disease (CD) symptoms may be reduced if an agonist of the retinoic acid receptor alpha (RARA) can be used to traffic T-regulatory (Treg) cells to inflamed intestinal tissues, researchers suggest.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IqtfLI

Sleep Boosts T-Cell Antiviral Potency Sleep Boosts T-Cell Antiviral Potency

It looks like your mother was right: when you've got a cold, sleep may be the best medicine.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GtSQSd

Pioneering surgery to regrow woman’s jaw hailed a ‘success’

Source: www.breakingnews.ie Author: staff A pioneering operation to regrow a woman's jaw from her own skin and bone after she lost […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SRSVVP

Scientists to test light therapy as relief from side effects of cancer treatment

Source: www.photonics.com Author: staff University at Buffalo (UB) researchers have received part of a $1.5 million grant to investigate light therapy […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2EbfQmX

E-cigarette users show cancer-linked genetic changes

Source:news.usc.edu Author: Leigh Hopper If you think vaping is benign, think again. A USC study in 93 people shows that e-cigarette […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IppS8a

Foetal radiation exposure caused by mechanical thrombectomy in large-vessel ischaemic stroke in pregnancy

Abstract

Purpose

There is overwhelming evidence for the clinical benefits that are derived following mechanical thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergone mechanical thrombectomy in pregnancy, thus demonstrating the feasibility of the procedure; however, there is no data on the radiation exposure to the mother or foetus related to this therapy.

Methods

We highlight the important technical considerations to minimise the risk of the procedure and report the estimated dose received by mother and foetus. We also compare these doses with those received during whole-body CT in trauma and CT pulmonary angiogram (CTPA) examinations.

Results

Three cases of mechanical thrombectomy were performed at separate tertiary referral neuroscience centres in the UK. Following diagnostic CT and mechanical thrombectomy, the total whole-body effective dose to the pregnant patient was significantly higher than in patients undergoing CTPA (p < 0.05), but not significant different compared to whole-body CT imaging in trauma patients. The estimated dose received by the foetus following diagnostic CT and mechanical thrombectomy was significantly lower than in whole-body imaging in trauma patients at p < 0.05, with no difference in estimated foetal dose compared to CTPA imaging.

Conclusion

The estimated doses received by the foetus during diagnostic stroke imaging and mechanical thrombectomy are equivalent to, or less than, purely diagnostic imaging in emergency situations.

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Pioneering surgery to regrow woman’s jaw hailed a ‘success’

Source: www.breakingnews.ie Author: staff A pioneering operation to regrow a woman's jaw from her own skin and bone after she lost […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SRSVVP

Scientists to test light therapy as relief from side effects of cancer treatment

Source: www.photonics.com Author: staff University at Buffalo (UB) researchers have received part of a $1.5 million grant to investigate light therapy […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2EbfQmX

E-cigarette users show cancer-linked genetic changes

Source:news.usc.edu Author: Leigh Hopper If you think vaping is benign, think again. A USC study in 93 people shows that e-cigarette […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IppS8a

Foetal radiation exposure caused by mechanical thrombectomy in large-vessel ischaemic stroke in pregnancy

Abstract

Purpose

There is overwhelming evidence for the clinical benefits that are derived following mechanical thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergone mechanical thrombectomy in pregnancy, thus demonstrating the feasibility of the procedure; however, there is no data on the radiation exposure to the mother or foetus related to this therapy.

Methods

We highlight the important technical considerations to minimise the risk of the procedure and report the estimated dose received by mother and foetus. We also compare these doses with those received during whole-body CT in trauma and CT pulmonary angiogram (CTPA) examinations.

Results

Three cases of mechanical thrombectomy were performed at separate tertiary referral neuroscience centres in the UK. Following diagnostic CT and mechanical thrombectomy, the total whole-body effective dose to the pregnant patient was significantly higher than in patients undergoing CTPA (p < 0.05), but not significant different compared to whole-body CT imaging in trauma patients. The estimated dose received by the foetus following diagnostic CT and mechanical thrombectomy was significantly lower than in whole-body imaging in trauma patients at p < 0.05, with no difference in estimated foetal dose compared to CTPA imaging.

Conclusion

The estimated doses received by the foetus during diagnostic stroke imaging and mechanical thrombectomy are equivalent to, or less than, purely diagnostic imaging in emergency situations.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GLX2MC

Pioneering surgery to regrow woman’s jaw hailed a ‘success’

Source: www.breakingnews.ie Author: staff A pioneering operation to regrow a woman's jaw from her own skin and bone after she lost […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SRSVVP

Pioneering surgery to regrow woman’s jaw hailed a ‘success’

Source: www.breakingnews.ie Author: staff A pioneering operation to regrow a woman's jaw from her own skin and bone after she lost […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SRSVVP

Scientists to test light therapy as relief from side effects of cancer treatment

Source: www.photonics.com Author: staff University at Buffalo (UB) researchers have received part of a $1.5 million grant to investigate light therapy […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2EbfQmX

Scientists to test light therapy as relief from side effects of cancer treatment

Source: www.photonics.com Author: staff University at Buffalo (UB) researchers have received part of a $1.5 million grant to investigate light therapy […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2EbfQmX

E-cigarette users show cancer-linked genetic changes

Source:news.usc.edu Author: Leigh Hopper If you think vaping is benign, think again. A USC study in 93 people shows that e-cigarette […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IppS8a

E-cigarette users show cancer-linked genetic changes

Source:news.usc.edu Author: Leigh Hopper If you think vaping is benign, think again. A USC study in 93 people shows that e-cigarette […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2IppS8a

Correction to: Collaborative and Reproducible Research: Goals, Challenges, and Strategies

The paper below had been published originally without open access, but has been republished with open access.

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Correction to: Collaborative and Reproducible Research: Goals, Challenges, and Strategies

The paper below had been published originally without open access, but has been republished with open access.

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Effects of Motor Imagery and Visual Neurofeedback on Activation in the Swallowing Network: A Real-Time fMRI Study

AbstractMotor imagery of movements is used as mental strategy in neurofeedback applications to gain voluntary control over activity in motor areas of the brain. In the present functional magnetic resonance imaging (fMRI) study, we first addressed the question whether motor imagery and execution of swallowing activate comparable brain areas, which has been already proven for hand and foot movements. Prior near-infrared spectroscopy (NIRS) studies provide evidence that this is the case in the outer layer of the cortex. With the present fMRI study, we want to expand these prior NIRS findings to the whole brain. Second, we used motor imagery of swallowing as mental strategy during visual neurofeedback to investigate whether one can learn to modulate voluntarily activity in brain regions, which...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SDbeP1

Effects of Motor Imagery and Visual Neurofeedback on Activation in the Swallowing Network: A Real-Time fMRI Study

AbstractMotor imagery of movements is used as mental strategy in neurofeedback applications to gain voluntary control over activity in motor areas of the brain. In the present functional magnetic resonance imaging (fMRI) study, we first addressed the question whether motor imagery and execution of swallowing activate comparable brain areas, which has been already proven for hand and foot movements. Prior near-infrared spectroscopy (NIRS) studies provide evidence that this is the case in the outer layer of the cortex. With the present fMRI study, we want to expand these prior NIRS findings to the whole brain. Second, we used motor imagery of swallowing as mental strategy during visual neurofeedback to investigate whether one can learn to modulate voluntarily activity in brain regions, which...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SDbeP1

Auditory Brainstem Implantation: An Overview

J Neurol Surg B DOI: 10.1055/s-0039-1679891An auditory brainstem implant (ABI) is a surgically implanted central neural auditory prosthesis for the treatment of profound sensorineural hearing loss in children and adults who are not cochlear implant candidates due to a lack of anatomically intact cochlear nerves or implantable cochleae. The device consists of a multielectrode surface array which is placed within the lateral recess of the fourth ventricle along the brainstem and directly stimulates the cochlear nucleus, thereby bypassing the peripheral auditory system. In the United States, candidacy criteria for ABI include deaf patients with neurofibromatosis type 2 (NF2) who are 12 years or older undergoing first- or second-side vestibular schwannoma resection. In recent years, several no...

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Temporal Bone Paraganglioma: Hearing Outcomes and Rehabilitation

The objective of this retrospective review is to provide a comprehensive review of hearing outcomes following the treatment of tympanojugular paragangliomas. A particular focus is placed on the variable audiologic outcomes as it relates to disease pathology, extent of disease, as well as chosen treatment modality. This review underscores the importance of considering treatment-related effects on hearing. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part B: Skull Base)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TSPZ8K

Auditory Brainstem Implantation: An Overview

J Neurol Surg B DOI: 10.1055/s-0039-1679891An auditory brainstem implant (ABI) is a surgically implanted central neural auditory prosthesis for the treatment of profound sensorineural hearing loss in children and adults who are not cochlear implant candidates due to a lack of anatomically intact cochlear nerves or implantable cochleae. The device consists of a multielectrode surface array which is placed within the lateral recess of the fourth ventricle along the brainstem and directly stimulates the cochlear nucleus, thereby bypassing the peripheral auditory system. In the United States, candidacy criteria for ABI include deaf patients with neurofibromatosis type 2 (NF2) who are 12 years or older undergoing first- or second-side vestibular schwannoma resection. In recent years, several no...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BC1Jp4

Temporal Bone Paraganglioma: Hearing Outcomes and Rehabilitation

The objective of this retrospective review is to provide a comprehensive review of hearing outcomes following the treatment of tympanojugular paragangliomas. A particular focus is placed on the variable audiologic outcomes as it relates to disease pathology, extent of disease, as well as chosen treatment modality. This review underscores the importance of considering treatment-related effects on hearing. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part B: Skull Base)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TSPZ8K

Peri‐implantitis prevalence, incidence rate and risk factors: A study of electronic health records at a U.S. dental school

Abstract

Objectives

We assessed peri‐implantitis prevalence, incidence rate and associated risk factors by analyzing electronic oral health records (EHRs) in an educational institution.

Methods

We used a validated reference cohort comprising all patients receiving dental implants over a 3.5‐year period (2,127 patients and 6,129 implants). EHRs of a random 10% subset were examined for an additional follow‐up of ≥2.5 years to assess presence of radiographic bone loss, defined as >2mm longitudinal increase in the distance between the implant shoulder and the supporting peri‐implant bone level (PBL) between time of placement and follow‐up. "Intact" implants had no or ≤2mm PBL increase from baseline. EHR notes were reviewed to corroborate a definitive peri‐implantitis diagnosis at implants with progressive bone loss. A nested case‐control analysis of peri‐implantitis‐affected implants randomly matched by age with "intact" implants from peri‐implantitis‐free individuals identified putative risk factors.

Results

The prevalence of peri‐implantitis over an average follow‐up of _˜2 years was 34% on the patient‐ and 21% on the implant level. Corresponding incidence rates were 0.16 and 0.10 per patient‐year and implant‐year, respectively. Multiple conditional logistic regression identified ill‐fitting fixed prosthesis (OR=5.9; 95%CI 1.6‐21.1), cement‐retained prosthesis (OR=4.5; 2.1‐9.5), and radiographic evidence of periodontitis (OR=3.6; 1.7‐7.6) as statistically associated with peri‐implantitis. Implant location in the mandible (OR=0.02; 0.003‐0.2) and use of antibiotics in conjunction with implant surgery (OR=0.19; 0.05‐0.7) emerged as protective exposures.

Conclusions

Approximately 1/3 of the patients and 1/5 of all implants experienced peri‐implantitis. Ill‐fitting/ill‐designed fixed and cement‐retained restorations, and history of periodontitis emerged as the principal risk factors for peri‐implantitis.

This article is protected by copyright. All rights reserved.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GNeqk3

Peri‐implantitis prevalence, incidence rate and risk factors: A study of electronic health records at a U.S. dental school

Abstract

Objectives

We assessed peri‐implantitis prevalence, incidence rate and associated risk factors by analyzing electronic oral health records (EHRs) in an educational institution.

Methods

We used a validated reference cohort comprising all patients receiving dental implants over a 3.5‐year period (2,127 patients and 6,129 implants). EHRs of a random 10% subset were examined for an additional follow‐up of ≥2.5 years to assess presence of radiographic bone loss, defined as >2mm longitudinal increase in the distance between the implant shoulder and the supporting peri‐implant bone level (PBL) between time of placement and follow‐up. "Intact" implants had no or ≤2mm PBL increase from baseline. EHR notes were reviewed to corroborate a definitive peri‐implantitis diagnosis at implants with progressive bone loss. A nested case‐control analysis of peri‐implantitis‐affected implants randomly matched by age with "intact" implants from peri‐implantitis‐free individuals identified putative risk factors.

Results

The prevalence of peri‐implantitis over an average follow‐up of _˜2 years was 34% on the patient‐ and 21% on the implant level. Corresponding incidence rates were 0.16 and 0.10 per patient‐year and implant‐year, respectively. Multiple conditional logistic regression identified ill‐fitting fixed prosthesis (OR=5.9; 95%CI 1.6‐21.1), cement‐retained prosthesis (OR=4.5; 2.1‐9.5), and radiographic evidence of periodontitis (OR=3.6; 1.7‐7.6) as statistically associated with peri‐implantitis. Implant location in the mandible (OR=0.02; 0.003‐0.2) and use of antibiotics in conjunction with implant surgery (OR=0.19; 0.05‐0.7) emerged as protective exposures.

Conclusions

Approximately 1/3 of the patients and 1/5 of all implants experienced peri‐implantitis. Ill‐fitting/ill‐designed fixed and cement‐retained restorations, and history of periodontitis emerged as the principal risk factors for peri‐implantitis.

This article is protected by copyright. All rights reserved.

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Pathology of the carotid space

Abstract

The complex anatomy of the carotid space within a small confined area is unique to the head and neck and allows for a vast array of pathology. This paper will review the anatomy of the carotid space from the skull base to the thorax, defining its borders at multiple levels, as well as its contents. The paper will also describe the myriad of mass lesions and vascular pathologies that may occur within the carotid space. The discussion will include anatomic considerations in differential diagnoses, imaging features, and lesion characteristics across multiple imaging modalities including CT, MRI, ultrasound, and conventional angiography. Entities discussed include paragangliomas, nerve sheath tumors, meningioma, fibromuscular dysplasia, carotidynia, thrombus, dissection, pseudoaneurysm, and pathology of the deep cervical chain lymph nodes. Understanding the complex and unique anatomy of the carotid space, as well as the nuances of navigating a broad differential, will empower the reader to make an accurate diagnosis.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2X5LKbG

Pathology of the carotid space

Abstract

The complex anatomy of the carotid space within a small confined area is unique to the head and neck and allows for a vast array of pathology. This paper will review the anatomy of the carotid space from the skull base to the thorax, defining its borders at multiple levels, as well as its contents. The paper will also describe the myriad of mass lesions and vascular pathologies that may occur within the carotid space. The discussion will include anatomic considerations in differential diagnoses, imaging features, and lesion characteristics across multiple imaging modalities including CT, MRI, ultrasound, and conventional angiography. Entities discussed include paragangliomas, nerve sheath tumors, meningioma, fibromuscular dysplasia, carotidynia, thrombus, dissection, pseudoaneurysm, and pathology of the deep cervical chain lymph nodes. Understanding the complex and unique anatomy of the carotid space, as well as the nuances of navigating a broad differential, will empower the reader to make an accurate diagnosis.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2X5LKbG

Longitudinal assessment of cerebral blood flow changes following carotid artery stenting and endarterectomy

Abstract

Background

Carotid artery stenting (CAS) and endarterectomy (CEA) are major treatment strategies for patients with internal carotid artery (ICA) stenosis; however, the dynamic cerebral blood flow (CBF) changes after CAS and CEA remain unclear.

Purpose

This study aimed to monitor consecutive CBF changes at 24-h intervals in patients who underwent CAS and CEA to explore the potential pattern of CBF alternation and compare the effect on CBF changes of different surgical methods.

Methods

Thirty-two patients (28 males and 4 females; age = 63.0 ± 7.3 years) with 70–99% ipsilateral stenosis in the ICA were enrolled, of which 19 underwent CAS and 13 underwent CEA by prospective cross-sectional study. Routine head MRI and three-dimensional pseudo-continuous arterial spin labeling were performed using a 3.0-T system within 7 days prior to operations, and at 4 consecutive time-points (24, 48, 72, and 96 h) after operations. Comparisons within groups were made using paired t test, and comparisons between groups were made using independent-sample t test.

Results

The CBF values markedly increased at 24 h after CAS and CEA (P < 0.05) compared with baseline. Most patients showed peak CBF values on the ipsilateral side at 72 h (13/19, 68%) after CAS and at 48 h (10/13, 77%) after CEA, which then declined. The CBF values for the ipsilateral ICA territory of CEA group were higher than those of CAS group at 24, 48, 72, and 96 h (P < 0.05).

Conclusions

The pattern of dynamic CBF changes is different after CAS and CEA, which may be helpful for the improvement of the patient's postoperative management.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2X52WOI

Longitudinal assessment of cerebral blood flow changes following carotid artery stenting and endarterectomy

Abstract

Background

Carotid artery stenting (CAS) and endarterectomy (CEA) are major treatment strategies for patients with internal carotid artery (ICA) stenosis; however, the dynamic cerebral blood flow (CBF) changes after CAS and CEA remain unclear.

Purpose

This study aimed to monitor consecutive CBF changes at 24-h intervals in patients who underwent CAS and CEA to explore the potential pattern of CBF alternation and compare the effect on CBF changes of different surgical methods.

Methods

Thirty-two patients (28 males and 4 females; age = 63.0 ± 7.3 years) with 70–99% ipsilateral stenosis in the ICA were enrolled, of which 19 underwent CAS and 13 underwent CEA by prospective cross-sectional study. Routine head MRI and three-dimensional pseudo-continuous arterial spin labeling were performed using a 3.0-T system within 7 days prior to operations, and at 4 consecutive time-points (24, 48, 72, and 96 h) after operations. Comparisons within groups were made using paired t test, and comparisons between groups were made using independent-sample t test.

Results

The CBF values markedly increased at 24 h after CAS and CEA (P < 0.05) compared with baseline. Most patients showed peak CBF values on the ipsilateral side at 72 h (13/19, 68%) after CAS and at 48 h (10/13, 77%) after CEA, which then declined. The CBF values for the ipsilateral ICA territory of CEA group were higher than those of CAS group at 24, 48, 72, and 96 h (P < 0.05).

Conclusions

The pattern of dynamic CBF changes is different after CAS and CEA, which may be helpful for the improvement of the patient's postoperative management.

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Successful treatment with omalizumab of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis: case reports and literature review

Publication date: Available online 15 February 2019

Source: The Journal of Allergy and Clinical Immunology: In Practice

Author(s): Giuseppe Fabio Parisi, Anna Portale, Maria Papale, Lucia Tardino, Novella Rotolo, Amelia Licari, Salvatore Leonardi

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Long-term outcomes with subcutaneous C1-inhibitor replacement therapy for prevention of hereditary angioedema attacks

Publication date: Available online 15 February 2019

Source: The Journal of Allergy and Clinical Immunology: In Practice

Author(s): Timothy Craig, Bruce Zuraw, Hilary Longhurst, Marco Cicardi, Konrad Bork, Clive Grattan, Constance Katelaris, Gordon Sussman, Paul K. Keith, William Yang, Jacques Hébert, Jana Hanzlikova, Petra Staubach-Renz, Inmaculada Martinez-Saguer, Markus Magerl, Emel Aygören-Pürsün, Henriette Farkas, Avner Reshef, Shmuel Kivity, Sergio Neri

Abstract

BACKGROUND

For the prevention of attacks of hereditary angioedema (HAE), the efficacy and safety of subcutaneous human C1-esterase inhibitor (C1-INH[SC]; HAEGARDA^®, CSL Behring) was established in the 16-week COMPACT trial.

OBJECTIVE

To assess the long-term safety, occurrence of angioedema attacks, and use of rescue medication with C1-INH(SC).

METHODS

Open-label, randomised, parallel-arm extension of COMPACT across 11 countries. Patients with frequent angioedema attacks, either study treatment-naïve or who had completed the COMPACT trial, were randomly assigned (1:1) to 40 IU/kg or 60 IU/kg C1-INH(SC) twice per week, with conditional up-titration to optimise prophylaxis. ClinicalTrials.gov registration: NCT02316353.

RESULTS

126 patients with a monthly attack rate of 4.3 in 3 months prior to entry in the COMPACT program were enrolled and treated for a mean of 1·5 years; 44 patients (34·9%) had >2 years exposure. Median steady-state C1-INH functional activity increased to a maximum of 73.0% with 60 IU/kg. Incidence of adverse events was low and similar in both dose groups (11·3 and 8·5 events per patient-year for 40 IU/kg and 60 IU/kg, respectively). For 40 IU/kg and 60 IU/kg, median annualised attack rates were 1·3 and 1·0, respectively and median rescue medication use was 0.2 and 0.0 times per year, respectively. Of 23 patients receiving 60 IU/kg for >2 years, 19 (83%) were attack-free during months 25–30 of treatment.

CONCLUSION

In patients with frequent HAE attacks, long-term replacement therapy with C1-INH(SC) is safe and exhibits a substantial and sustained prophylactic effect, with the vast majority of patients becoming free from debilitating disease symptoms.

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Trends in Asthma Control, Treatment, Healthcare Utilization and Expenditures among Children in the United States by Place of Residence: 2003-2014

Publication date: Available online 15 February 2019

Source: The Journal of Allergy and Clinical Immunology: In Practice

Author(s): Patrick W. Sullivan, Ghushchyan Vahram, Kavati Abhishek, Navaratnam Prakash, Howard S. Friedman, Ortiz Benjamin

Abstract

Background

Examining national trends in asthma treatment and control is essential to inform treatment and public health initiatives.

Objective

Explore national trends in asthma control and treatment over time among children and those residing in poor-urban areas.

Methods

This was an analysis of trends from 2003-2014 among children (aged 1-17) in the Medical Expenditure Panel Survey (MEPS). Indicators of poor control included use of >3 canisters short-acting beta agonist (SABA) in 3 months, asthma attack, Emergency Department (ED)/inpatient (IP) hospitalization and systemic corticosteroids (SCS). Treatment included inhaled corticosteroids (ICS), controller medications, SABA and ratio of controller-to-total prescriptions ≥ 0.7. Other measures included the number of asthma medications, outpatient visits, asthma-specific drug and total expenditures per-patient-per-year.

Results

There were 8.4 million children with asthma in the U.S. in 2014; 11.1% lived in poor-urban areas. There was a statistically significant decrease in the percentage of children using ICS, controller medications, daily preventive medications, SCS, SABA, > 3 canisters SABA (in 3 months), overall asthma prescriptions and outpatient visits. There was a significant increase in the percentage of children reporting having an asthma attack. Trends for children residing in poor-urban areas were compared to all others, however, limited data and variability in annual estimates prevent clear conclusions.

Conclusion

Results suggest lack of improvement in treatment and control since 2003 among children with asthma in the U.S. There is significant room for improvement in asthma control and disease management among children.

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Successful treatment with omalizumab of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis: case reports and literature review

Publication date: Available online 15 February 2019

Source: The Journal of Allergy and Clinical Immunology: In Practice

Author(s): Giuseppe Fabio Parisi, Anna Portale, Maria Papale, Lucia Tardino, Novella Rotolo, Amelia Licari, Salvatore Leonardi

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2UYJXDB

Long-term outcomes with subcutaneous C1-inhibitor replacement therapy for prevention of hereditary angioedema attacks

Publication date: Available online 15 February 2019

Source: The Journal of Allergy and Clinical Immunology: In Practice

Author(s): Timothy Craig, Bruce Zuraw, Hilary Longhurst, Marco Cicardi, Konrad Bork, Clive Grattan, Constance Katelaris, Gordon Sussman, Paul K. Keith, William Yang, Jacques Hébert, Jana Hanzlikova, Petra Staubach-Renz, Inmaculada Martinez-Saguer, Markus Magerl, Emel Aygören-Pürsün, Henriette Farkas, Avner Reshef, Shmuel Kivity, Sergio Neri

Abstract

BACKGROUND

For the prevention of attacks of hereditary angioedema (HAE), the efficacy and safety of subcutaneous human C1-esterase inhibitor (C1-INH[SC]; HAEGARDA^®, CSL Behring) was established in the 16-week COMPACT trial.

OBJECTIVE

To assess the long-term safety, occurrence of angioedema attacks, and use of rescue medication with C1-INH(SC).

METHODS

Open-label, randomised, parallel-arm extension of COMPACT across 11 countries. Patients with frequent angioedema attacks, either study treatment-naïve or who had completed the COMPACT trial, were randomly assigned (1:1) to 40 IU/kg or 60 IU/kg C1-INH(SC) twice per week, with conditional up-titration to optimise prophylaxis. ClinicalTrials.gov registration: NCT02316353.

RESULTS

126 patients with a monthly attack rate of 4.3 in 3 months prior to entry in the COMPACT program were enrolled and treated for a mean of 1·5 years; 44 patients (34·9%) had >2 years exposure. Median steady-state C1-INH functional activity increased to a maximum of 73.0% with 60 IU/kg. Incidence of adverse events was low and similar in both dose groups (11·3 and 8·5 events per patient-year for 40 IU/kg and 60 IU/kg, respectively). For 40 IU/kg and 60 IU/kg, median annualised attack rates were 1·3 and 1·0, respectively and median rescue medication use was 0.2 and 0.0 times per year, respectively. Of 23 patients receiving 60 IU/kg for >2 years, 19 (83%) were attack-free during months 25–30 of treatment.

CONCLUSION

In patients with frequent HAE attacks, long-term replacement therapy with C1-INH(SC) is safe and exhibits a substantial and sustained prophylactic effect, with the vast majority of patients becoming free from debilitating disease symptoms.

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Trends in Asthma Control, Treatment, Healthcare Utilization and Expenditures among Children in the United States by Place of Residence: 2003-2014

Publication date: Available online 15 February 2019

Source: The Journal of Allergy and Clinical Immunology: In Practice

Author(s): Patrick W. Sullivan, Ghushchyan Vahram, Kavati Abhishek, Navaratnam Prakash, Howard S. Friedman, Ortiz Benjamin

Abstract

Background

Examining national trends in asthma treatment and control is essential to inform treatment and public health initiatives.

Objective

Explore national trends in asthma control and treatment over time among children and those residing in poor-urban areas.

Methods

This was an analysis of trends from 2003-2014 among children (aged 1-17) in the Medical Expenditure Panel Survey (MEPS). Indicators of poor control included use of >3 canisters short-acting beta agonist (SABA) in 3 months, asthma attack, Emergency Department (ED)/inpatient (IP) hospitalization and systemic corticosteroids (SCS). Treatment included inhaled corticosteroids (ICS), controller medications, SABA and ratio of controller-to-total prescriptions ≥ 0.7. Other measures included the number of asthma medications, outpatient visits, asthma-specific drug and total expenditures per-patient-per-year.

Results

There were 8.4 million children with asthma in the U.S. in 2014; 11.1% lived in poor-urban areas. There was a statistically significant decrease in the percentage of children using ICS, controller medications, daily preventive medications, SCS, SABA, > 3 canisters SABA (in 3 months), overall asthma prescriptions and outpatient visits. There was a significant increase in the percentage of children reporting having an asthma attack. Trends for children residing in poor-urban areas were compared to all others, however, limited data and variability in annual estimates prevent clear conclusions.

Conclusion

Results suggest lack of improvement in treatment and control since 2003 among children with asthma in the U.S. There is significant room for improvement in asthma control and disease management among children.

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