Primary Osteosarcoma of Sphenoid and Ethmoid Sinus in a 17 Year Female: Case Report

Abstract

Primary osteosarcoma of sphenoid and ethmoid sinus present as a challenge in head neck cancer. A 17 year female presented with left sided hemifacial pain, headache with nasal discharge. Clinico-radiological finding showed mass in sphenoethmoid recess spreading to adjacent structures. Endoscopic resection was done. Histopathological diagnosis was osteosarcoma of sphenoid and ethmoid sinus. Adjuvant chemotherapy administered. Osteosarcomas of sphenoid and ethmoid sinus are aggressive tumors with variable clinical features warranting high clinical suspicion.

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Inferior pole breast reconstruction by TDAP flap in post-burn breast contracture

Abstract

Background

Post-burn breast deformities are not an uncommon condition after severe second-degree or third-degree burn and present as severe asymmetry of the breast as compared to the opposite side, displacement of nipple-areola complex, obliteration of inframammary fold, and reduced breast projection. Based on deformities especially for lower pole breast contracture, we propose a new classification to describe breast contracture. There is no tailor-made approach described to deal such deformities. Various options are available ranging from skin graft to different flaps. We present reconstruction by TDAP flap after the release of breast contracture grades I and II. This study aimed to classify the lower pole breast contracture according to its severity and to evaluate the outcome of TDAP flap reconstruction and augmentation of the lower pole of the breast in terms of symmetry and aesthesis.

Methods

This is a descriptive retrospective study of 10 patients with 15 post-burn contracted breast affecting the inferior pole of the breast and inframammary fold within a period of January 2012 to March 2016 in Kasralainy hospital, Cairo. All cases were evaluated according to flap vascularity, donor site morbidity, symmetry, and esthetic outcome.

Results

All flaps survived completely. Flap dimension ranged from 18 × 10 to 22 × 12 cm. The muscle sparing design had been used in three patients due to lack of reliable perforators. Patients were evaluated for their satisfaction, and all of them were satisfied.

Conclusions

It is essential to classify the grade of post-burn lower pole breast contracture according to the proposed classification. TDAP is a valuable option in case of grade I and II deformities only. For severe grade III breast contracture, more volume restoring procedure is advisable.

Level of Evidence: Level IV, therapeutic study.

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Primary Osteosarcoma of Sphenoid and Ethmoid Sinus in a 17 Year Female: Case Report

Abstract

Primary osteosarcoma of sphenoid and ethmoid sinus present as a challenge in head neck cancer. A 17 year female presented with left sided hemifacial pain, headache with nasal discharge. Clinico-radiological finding showed mass in sphenoethmoid recess spreading to adjacent structures. Endoscopic resection was done. Histopathological diagnosis was osteosarcoma of sphenoid and ethmoid sinus. Adjuvant chemotherapy administered. Osteosarcomas of sphenoid and ethmoid sinus are aggressive tumors with variable clinical features warranting high clinical suspicion.

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Inferior pole breast reconstruction by TDAP flap in post-burn breast contracture

Abstract

Background

Post-burn breast deformities are not an uncommon condition after severe second-degree or third-degree burn and present as severe asymmetry of the breast as compared to the opposite side, displacement of nipple-areola complex, obliteration of inframammary fold, and reduced breast projection. Based on deformities especially for lower pole breast contracture, we propose a new classification to describe breast contracture. There is no tailor-made approach described to deal such deformities. Various options are available ranging from skin graft to different flaps. We present reconstruction by TDAP flap after the release of breast contracture grades I and II. This study aimed to classify the lower pole breast contracture according to its severity and to evaluate the outcome of TDAP flap reconstruction and augmentation of the lower pole of the breast in terms of symmetry and aesthesis.

Methods

This is a descriptive retrospective study of 10 patients with 15 post-burn contracted breast affecting the inferior pole of the breast and inframammary fold within a period of January 2012 to March 2016 in Kasralainy hospital, Cairo. All cases were evaluated according to flap vascularity, donor site morbidity, symmetry, and esthetic outcome.

Results

All flaps survived completely. Flap dimension ranged from 18 × 10 to 22 × 12 cm. The muscle sparing design had been used in three patients due to lack of reliable perforators. Patients were evaluated for their satisfaction, and all of them were satisfied.

Conclusions

It is essential to classify the grade of post-burn lower pole breast contracture according to the proposed classification. TDAP is a valuable option in case of grade I and II deformities only. For severe grade III breast contracture, more volume restoring procedure is advisable.

Level of Evidence: Level IV, therapeutic study.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TMi7dA

Inferior pole breast reconstruction by TDAP flap in post-burn breast contracture

Abstract

Background

Post-burn breast deformities are not an uncommon condition after severe second-degree or third-degree burn and present as severe asymmetry of the breast as compared to the opposite side, displacement of nipple-areola complex, obliteration of inframammary fold, and reduced breast projection. Based on deformities especially for lower pole breast contracture, we propose a new classification to describe breast contracture. There is no tailor-made approach described to deal such deformities. Various options are available ranging from skin graft to different flaps. We present reconstruction by TDAP flap after the release of breast contracture grades I and II. This study aimed to classify the lower pole breast contracture according to its severity and to evaluate the outcome of TDAP flap reconstruction and augmentation of the lower pole of the breast in terms of symmetry and aesthesis.

Methods

This is a descriptive retrospective study of 10 patients with 15 post-burn contracted breast affecting the inferior pole of the breast and inframammary fold within a period of January 2012 to March 2016 in Kasralainy hospital, Cairo. All cases were evaluated according to flap vascularity, donor site morbidity, symmetry, and esthetic outcome.

Results

All flaps survived completely. Flap dimension ranged from 18 × 10 to 22 × 12 cm. The muscle sparing design had been used in three patients due to lack of reliable perforators. Patients were evaluated for their satisfaction, and all of them were satisfied.

Conclusions

It is essential to classify the grade of post-burn lower pole breast contracture according to the proposed classification. TDAP is a valuable option in case of grade I and II deformities only. For severe grade III breast contracture, more volume restoring procedure is advisable.

Level of Evidence: Level IV, therapeutic study.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TMi7dA

Inferior pole breast reconstruction by TDAP flap in post-burn breast contracture

Abstract

Background

Post-burn breast deformities are not an uncommon condition after severe second-degree or third-degree burn and present as severe asymmetry of the breast as compared to the opposite side, displacement of nipple-areola complex, obliteration of inframammary fold, and reduced breast projection. Based on deformities especially for lower pole breast contracture, we propose a new classification to describe breast contracture. There is no tailor-made approach described to deal such deformities. Various options are available ranging from skin graft to different flaps. We present reconstruction by TDAP flap after the release of breast contracture grades I and II. This study aimed to classify the lower pole breast contracture according to its severity and to evaluate the outcome of TDAP flap reconstruction and augmentation of the lower pole of the breast in terms of symmetry and aesthesis.

Methods

This is a descriptive retrospective study of 10 patients with 15 post-burn contracted breast affecting the inferior pole of the breast and inframammary fold within a period of January 2012 to March 2016 in Kasralainy hospital, Cairo. All cases were evaluated according to flap vascularity, donor site morbidity, symmetry, and esthetic outcome.

Results

All flaps survived completely. Flap dimension ranged from 18 × 10 to 22 × 12 cm. The muscle sparing design had been used in three patients due to lack of reliable perforators. Patients were evaluated for their satisfaction, and all of them were satisfied.

Conclusions

It is essential to classify the grade of post-burn lower pole breast contracture according to the proposed classification. TDAP is a valuable option in case of grade I and II deformities only. For severe grade III breast contracture, more volume restoring procedure is advisable.

Level of Evidence: Level IV, therapeutic study.

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ALLERGY MIX LOS ANGELES (Local Remedy Los Angeles) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

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ALLERGY MIX LAS VEGAS (Local Remedy Las Vegas) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

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ALLERGY MIX PHOENIX (Local Remedy Phoenix) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

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ALLERGY MIX LOS ANGELES (Local Remedy Los Angeles) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

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ALLERGY MIX LOS ANGELES (Local Remedy Los Angeles) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

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ALLERGY MIX LAS VEGAS (Local Remedy Las Vegas) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tinnKh

ALLERGY MIX PHOENIX (Local Remedy Phoenix) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

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ALLERGY MIX LOS ANGELES (Local Remedy Los Angeles) Tablet, Chewable [ASN]

Updated Date: Feb 12, 2019 EST (Source: DailyMed Drug Label Updates)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

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TOPCARE ALLERGY RELIEF (Fexofenadine Hydrochloride) Tablet, Film Coated [Topco Associates LLC]

Updated Date: Feb 7, 2019 EST (Source: DailyMed Drug Label Updates)

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Primary Tonsillar Epithelioid Follicular Dendritic Cell Sarcoma: Report of a Rare Case Mimicking Undifferentiated Carcinoma and a Brief Review of the Literature

Abstract

We present a 52 years old male with a left tonsillar follicular dendritic cell sarcoma with prominent epithelioid features that on light microscopical examination bore a striking resemblance to a lymphoepithelial or undifferentiated carcinoma. The tumor was immunohistochemically positive for CD21 and CD35 and negative for cytokeratins. Two distinct histopathological features (both present in our case) that may serve as clues to the correct diagnosis on light microscopical examination were formation of ectatic pseudovascular spaces lined by malignant cells and the presence of non-neoplastic multinucleated giant cells. Familiarity with the above-mentioned morphological clues, and awareness that this tumour may occur in anatomical sites outside the lymph node, are essential for accurate diagnosis.

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Primary Tonsillar Epithelioid Follicular Dendritic Cell Sarcoma: Report of a Rare Case Mimicking Undifferentiated Carcinoma and a Brief Review of the Literature

Abstract

We present a 52 years old male with a left tonsillar follicular dendritic cell sarcoma with prominent epithelioid features that on light microscopical examination bore a striking resemblance to a lymphoepithelial or undifferentiated carcinoma. The tumor was immunohistochemically positive for CD21 and CD35 and negative for cytokeratins. Two distinct histopathological features (both present in our case) that may serve as clues to the correct diagnosis on light microscopical examination were formation of ectatic pseudovascular spaces lined by malignant cells and the presence of non-neoplastic multinucleated giant cells. Familiarity with the above-mentioned morphological clues, and awareness that this tumour may occur in anatomical sites outside the lymph node, are essential for accurate diagnosis.

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A hierarchical sparse coding model predicts acoustic feature encoding in both auditory midbrain and cortex

by Qingtian Zhang, Xiaolin Hu, Bo Hong, Bo Zhang The auditory pathway consists of multiple stages, from the cochlear nucleus to the auditory cortex. Neurons acting at different stages have different functions and exhibit different response properties. It is unclear whether these stages share a common encoding mechanism. We trained an unsupervise d deep learning model consisting of alternating sparse coding and max pooling layers on cochleogram-filtered human speech. Evaluation of the response properties revealed that computing units in lower layers exhibited spectro-temporal receptive fields (STRFs) similar to those of inferior colliculus n eurons measured in physiological experiments, including properties such as sound onset and termination, checkerboard pattern, and spectral motion. Uni...

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A hierarchical sparse coding model predicts acoustic feature encoding in both auditory midbrain and cortex

by Qingtian Zhang, Xiaolin Hu, Bo Hong, Bo Zhang The auditory pathway consists of multiple stages, from the cochlear nucleus to the auditory cortex. Neurons acting at different stages have different functions and exhibit different response properties. It is unclear whether these stages share a common encoding mechanism. We trained an unsupervise d deep learning model consisting of alternating sparse coding and max pooling layers on cochleogram-filtered human speech. Evaluation of the response properties revealed that computing units in lower layers exhibited spectro-temporal receptive fields (STRFs) similar to those of inferior colliculus n eurons measured in physiological experiments, including properties such as sound onset and termination, checkerboard pattern, and spectral motion. Uni...

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Reference range determination for imaging biomarkers: Myocardial T1

Background

Imaging biomarkers, such as the T₁ relaxation time of the myocardium using MRI, can be valuable in cardiac medicine if they are properly validated. Consensus statements recommend that for myocardial T₁, each investigator should establish a reference range.

Purpose

To describe a statistically valid method for determining and reporting the reference range in each center, which simultaneously minimizes the twin risks of undersampling, leading to a uselessly uncertain range, and oversampling, which exposes volunteers to unnecessary scanning and wastes resources.

Study Type

Cohort.

Population

In all, 278 normal human subjects without cardiac disease from two cardiac MR centers.

Field Strength/Sequence

1.5 T and 3 T; Modified Look–Locker Inversion recovery sequence.

Assessment

The T₁ relaxation time was estimated from multiple samples of tissue magnetization after inversion. A valid method for calculating a reference range was used.

Statistical Tests

Shapiro–Wilk test for normality; Tukey robust approach for identification of outliers; reference range calculation with confidence intervals.

Results

Reference ranges for measurement of myocardial T₁ were calculated, with confidence intervals, enabling comparison with clinically important differences. At 3 T: 1129 to 1301 msec at site 1 (n = 21) and 1160 to 1309 msec at site 2 (n = 59), and at 1.5 T at site 2: 933 to 1020 msec (male, n = 130) and 965 to 1054 msec (female, n = 68). The 3 T reference range from site 1 was successfully benchmarked against the 3 T reference range at site 2.

Data Conclusion

Myocardial T₁ reference ranges can be properly characterized, enabling clinical comparison to a valid reference range with known confidence intervals, using methodology similar to that described in this report.

Level of Evidence: 3

Technical Efficacy Stage: 3

J. Magn. Reson. Imaging 2019.

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Reference range determination for imaging biomarkers: Myocardial T1

Background

Imaging biomarkers, such as the T₁ relaxation time of the myocardium using MRI, can be valuable in cardiac medicine if they are properly validated. Consensus statements recommend that for myocardial T₁, each investigator should establish a reference range.

Purpose

To describe a statistically valid method for determining and reporting the reference range in each center, which simultaneously minimizes the twin risks of undersampling, leading to a uselessly uncertain range, and oversampling, which exposes volunteers to unnecessary scanning and wastes resources.

Study Type

Cohort.

Population

In all, 278 normal human subjects without cardiac disease from two cardiac MR centers.

Field Strength/Sequence

1.5 T and 3 T; Modified Look–Locker Inversion recovery sequence.

Assessment

The T₁ relaxation time was estimated from multiple samples of tissue magnetization after inversion. A valid method for calculating a reference range was used.

Statistical Tests

Shapiro–Wilk test for normality; Tukey robust approach for identification of outliers; reference range calculation with confidence intervals.

Results

Reference ranges for measurement of myocardial T₁ were calculated, with confidence intervals, enabling comparison with clinically important differences. At 3 T: 1129 to 1301 msec at site 1 (n = 21) and 1160 to 1309 msec at site 2 (n = 59), and at 1.5 T at site 2: 933 to 1020 msec (male, n = 130) and 965 to 1054 msec (female, n = 68). The 3 T reference range from site 1 was successfully benchmarked against the 3 T reference range at site 2.

Data Conclusion

Myocardial T₁ reference ranges can be properly characterized, enabling clinical comparison to a valid reference range with known confidence intervals, using methodology similar to that described in this report.

Level of Evidence: 3

Technical Efficacy Stage: 3

J. Magn. Reson. Imaging 2019.

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Contribution of Nitric oxide synthase 3 genetic variants to nasopharyngeal carcinoma risk and progression in a Tunisian population

Abstract

Purpose

We conduct this study to evaluate the clinical and functional impact of Nitric Oxide Synthase 3 (NOS3) T-786C and G894T genetic variants on nasopharyngeal carcinoma (NPC) risk and progression in a Tunisian population.

Methods

259 NPC patients and 169 healthy controls were enrolled into our case–control study. Blood samples were genotyped by the RFLP-PCR analysis. The levels of Nitric oxide (NO) were measured by a colorimetric assay kit in the plasma of NPC patients, healthy controls and according to NOS3 genotypes. The correlation between the NOS3 variants and the clinicopathological parameters was examined.

Results

We found no linkage disequilibrium between NOS3 T-786C and G894T variants. These results showed that NOS3 variants were genetically independent. In contrast to NOS3 T-786C, a significant association was found between NOS3 G894T polymorphism and NPC risk. The 894T allele decreased significantly in NPC patients and appeared as protective factor (OR = 0.65, CI 95%= 0.48–0.88, p = 0.006). NPC patients had significantly higher levels of plasma NO as compared to healthy controls (p = 0.0011). The T-786C mutation reduced the levels of plasma NO and decreased risk of lymph node metastasis in NPC patients (OR = 0.64, 95% CI = 0.43–0.96; p = 0.03). In contrast, NOS3 G894T polymorphism had no effects neither on NO plasma levels nor clinical parameters.

Conclusions

This is the first study to associate NPC with significantly higher levels of plasma NO. NOS3-derived NO could play key roles in NPC pathogenesis. NOS3 variants differently contribute to NPC risk and progression in a Tunisian population. NOS3 G894T was associated with NPC risk. NOS3 T-786C decreased the levels of plasma NO and reduced the development of regional lymph node metastasis.

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Contribution of Nitric oxide synthase 3 genetic variants to nasopharyngeal carcinoma risk and progression in a Tunisian population

Abstract

Purpose

We conduct this study to evaluate the clinical and functional impact of Nitric Oxide Synthase 3 (NOS3) T-786C and G894T genetic variants on nasopharyngeal carcinoma (NPC) risk and progression in a Tunisian population.

Methods

259 NPC patients and 169 healthy controls were enrolled into our case–control study. Blood samples were genotyped by the RFLP-PCR analysis. The levels of Nitric oxide (NO) were measured by a colorimetric assay kit in the plasma of NPC patients, healthy controls and according to NOS3 genotypes. The correlation between the NOS3 variants and the clinicopathological parameters was examined.

Results

We found no linkage disequilibrium between NOS3 T-786C and G894T variants. These results showed that NOS3 variants were genetically independent. In contrast to NOS3 T-786C, a significant association was found between NOS3 G894T polymorphism and NPC risk. The 894T allele decreased significantly in NPC patients and appeared as protective factor (OR = 0.65, CI 95%= 0.48–0.88, p = 0.006). NPC patients had significantly higher levels of plasma NO as compared to healthy controls (p = 0.0011). The T-786C mutation reduced the levels of plasma NO and decreased risk of lymph node metastasis in NPC patients (OR = 0.64, 95% CI = 0.43–0.96; p = 0.03). In contrast, NOS3 G894T polymorphism had no effects neither on NO plasma levels nor clinical parameters.

Conclusions

This is the first study to associate NPC with significantly higher levels of plasma NO. NOS3-derived NO could play key roles in NPC pathogenesis. NOS3 variants differently contribute to NPC risk and progression in a Tunisian population. NOS3 G894T was associated with NPC risk. NOS3 T-786C decreased the levels of plasma NO and reduced the development of regional lymph node metastasis.

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Occupational acute generalized exanthematous pustulosis induced by disperse dyes in textile

Acute generalized exanthematous pustulosis (AGEP) is a severe eruption characterized by numerous non‐follicular sterile pustules on an erythematous background. AGEP is mostly caused by systemic drugs mainly antibiotics. Others causes of AGEP, such as contact with mercury, spider bites and viral infection had been described.¹

This article is protected by copyright. All rights reserved.

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Occupational acute generalized exanthematous pustulosis induced by disperse dyes in textile

Acute generalized exanthematous pustulosis (AGEP) is a severe eruption characterized by numerous non‐follicular sterile pustules on an erythematous background. AGEP is mostly caused by systemic drugs mainly antibiotics. Others causes of AGEP, such as contact with mercury, spider bites and viral infection had been described.¹

This article is protected by copyright. All rights reserved.

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High dietary fat intake induces a microbiota signature that promotes food allergy

Post-dieting microbiome alterations due to over indulgence of dietary fat increase susceptibility to experimental food allergy independent of obesity and metabolic derangements. (Source: Journal of Allergy and Clinical Immunology)

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Interleukin-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

IL-4 receptor engagement in human neutrophils impairs their formation of extracellular traps and their in vitro and in vivo chemotaxis. (Source: Journal of Allergy and Clinical Immunology)

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Drug Hypersensitivity Reactions in Children: Are there factors associated with severity?

This study analyzes and describes potential factors associated with severity of DHR in children. (Source: Journal of Allergy and Clinical Immunology)

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Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity

Nasal epithelial transcriptome is altered by the season. Birch pollen allergen immunotherapy recovers microbial community diversity and alters expression of allergy related genes. (Source: Journal of Allergy and Clinical Immunology)

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High dietary fat intake induces a microbiota signature that promotes food allergy

Post-dieting microbiome alterations due to over indulgence of dietary fat increase susceptibility to experimental food allergy independent of obesity and metabolic derangements. (Source: Journal of Allergy and Clinical Immunology)

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Interleukin-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

IL-4 receptor engagement in human neutrophils impairs their formation of extracellular traps and their in vitro and in vivo chemotaxis. (Source: Journal of Allergy and Clinical Immunology)

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Drug Hypersensitivity Reactions in Children: Are there factors associated with severity?

This study analyzes and describes potential factors associated with severity of DHR in children. (Source: Journal of Allergy and Clinical Immunology)

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Quick DNA test that could save newborns from deafness

Hospitals in Manchester and Liverpool will carry out the NHS trial of the DNA test, which identifies babies at risk of losing their hearing if given the common antibiotic gentamicin. (Source: the Mail online | Health)

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Deaf moth evolves sound-production as a warning to outwit its predator

(University of Bristol) A genus of deaf moth has evolved to develop an extraordinary sound-producing structure in its wings to evade its primary predator the bat. The finding, made by researchers from the University of Bristol and Natural History Museum, is described in Scientific Reports today. (Source: EurekAlert! - Biology)

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How Do You Get Rid of Ringing in the Ears (Tinnitus)?

Title: How Do You Get Rid of Ringing in the Ears (Tinnitus)?Category: Diseases and ConditionsCreated: 2/4/2019 12:00:00 AMLast Editorial Review: 2/4/2019 12:00:00 AM (Source: MedicineNet Hearing General)

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Quick DNA test that could save newborns from deafness

Hospitals in Manchester and Liverpool will carry out the NHS trial of the DNA test, which identifies babies at risk of losing their hearing if given the common antibiotic gentamicin. (Source: the Mail online | Health)

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Deaf moth evolves sound-production as a warning to outwit its predator

(University of Bristol) A genus of deaf moth has evolved to develop an extraordinary sound-producing structure in its wings to evade its primary predator the bat. The finding, made by researchers from the University of Bristol and Natural History Museum, is described in Scientific Reports today. (Source: EurekAlert! - Biology)

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How Do You Get Rid of Ringing in the Ears (Tinnitus)?

Title: How Do You Get Rid of Ringing in the Ears (Tinnitus)?Category: Diseases and ConditionsCreated: 2/4/2019 12:00:00 AMLast Editorial Review: 2/4/2019 12:00:00 AM (Source: MedicineNet Hearing General)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WVn5GZ

Quick DNA test that could save newborns from deafness

Hospitals in Manchester and Liverpool will carry out the NHS trial of the DNA test, which identifies babies at risk of losing their hearing if given the common antibiotic gentamicin. (Source: the Mail online | Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WZJB17

Deaf moth evolves sound-production as a warning to outwit its predator

(University of Bristol) A genus of deaf moth has evolved to develop an extraordinary sound-producing structure in its wings to evade its primary predator the bat. The finding, made by researchers from the University of Bristol and Natural History Museum, is described in Scientific Reports today. (Source: EurekAlert! - Biology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2RXpcq3

How Do You Get Rid of Ringing in the Ears (Tinnitus)?

Title: How Do You Get Rid of Ringing in the Ears (Tinnitus)?Category: Diseases and ConditionsCreated: 2/4/2019 12:00:00 AMLast Editorial Review: 2/4/2019 12:00:00 AM (Source: MedicineNet Hearing General)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WVn5GZ

Quick DNA test that could save newborns from deafness

Hospitals in Manchester and Liverpool will carry out the NHS trial of the DNA test, which identifies babies at risk of losing their hearing if given the common antibiotic gentamicin. (Source: the Mail online | Health)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WZJB17

Deaf moth evolves sound-production as a warning to outwit its predator

(University of Bristol) A genus of deaf moth has evolved to develop an extraordinary sound-producing structure in its wings to evade its primary predator the bat. The finding, made by researchers from the University of Bristol and Natural History Museum, is described in Scientific Reports today. (Source: EurekAlert! - Biology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2RXpcq3

How Do You Get Rid of Ringing in the Ears (Tinnitus)?

Title: How Do You Get Rid of Ringing in the Ears (Tinnitus)?Category: Diseases and ConditionsCreated: 2/4/2019 12:00:00 AMLast Editorial Review: 2/4/2019 12:00:00 AM (Source: MedicineNet Hearing General)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WVn5GZ

Aaaai 2019 aaaai 2019

Read clinically focused news coverage of key developments from AAAAI 2019Medscape Allergy & Immunology (Source: Medscape Today Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3reUC

Apple to launch Health Records eHR mobile app in U.S. Veterans Affairs deal

Apple (NSDQ:AAPL) said yesterday that it is preparing to launch its new Health Records mobile electronic health records feature for U.S. Veterans as part of a partnership with the U.S. Veteran's Health Administration. With the launch, veterans will be able to view their aggregated health records directly through the iHealth application on their iPhone devices, the tech giant said. Health record data will include allergies, conditions, immunizations, lab results, medications, procedures and vitals and will be displayed alongside other data, including fitness and active monitoring data from connected devices, the company said. The files will be encrypted and protected through the use of the device's passcode, Touch ID or Face ID biometric security verification, Apple said. "We hav...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SGOD3u

Aaaai 2019 aaaai 2019

Read clinically focused news coverage of key developments from AAAAI 2019Medscape Allergy & Immunology (Source: Medscape Today Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3reUC

Apple to launch Health Records eHR mobile app in U.S. Veterans Affairs deal

Apple (NSDQ:AAPL) said yesterday that it is preparing to launch its new Health Records mobile electronic health records feature for U.S. Veterans as part of a partnership with the U.S. Veteran's Health Administration. With the launch, veterans will be able to view their aggregated health records directly through the iHealth application on their iPhone devices, the tech giant said. Health record data will include allergies, conditions, immunizations, lab results, medications, procedures and vitals and will be displayed alongside other data, including fitness and active monitoring data from connected devices, the company said. The files will be encrypted and protected through the use of the device's passcode, Touch ID or Face ID biometric security verification, Apple said. "We hav...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SGOD3u

Systematic review of the role of corticosteroids in cervicofacial infections

The role of corticosteroids in the management of cervicofacial infections continues to cause controversy. Systemic anti-inflammatory and immunomodulatory effects that reduce swelling and improve symptoms in the head and neck may make these agents an effective addition to the antibiotics used and to surgical management, although this same effect may dull the physiological response to infection, and allow infections to progress. We have systematically reviewed the evidence for the use of corticosteroids in common cervicofacial infections following the PRISMA guidelines.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N0ApoE

Study in Cat-Allergic Patients With Asthma to Evaluate the Efficacy of a Single Dose of REGN1908-1909 to Reduce Bronchoconstriction Upon Cat Allergen Challenge

Conditions:   Cat Allergy;   Mild Asthma Interventions:   Drug: REGN1908-1909;   Drug: Placebo Sponsor:   Regeneron Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SvMRmw

Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV

Condition:   HIV-1-infection Interventions:   Drug: Saline;   Drug: Lefitolimod;   Drug: 3BNC117 and 10-1074 Sponsors:   University of Aarhus;   Aalborg Universitetshospital;   Odense University Hospital;   Rigshospitalet, Denmark;   Hvidovre University Hospital;   The Peter Doherty Institute for Infection and Immunity;   University of Utah Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DvtpMi

Prospective Study to Identify Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in Patients With Elevated Total Serum IgE Levels and Atopic Dermatitis

Conditions:   Milk Allergy;   Peanut Allergy Interventions:   Other: Peanut flour and Oat flour (placebo for peanut flour);   Other: Dry Milk Powder and Corn Starch (placebo for Milk powder);   Other: Baked milk and Rice milk (placebo for Baked milk) Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Institutes of Health Clinical Center (CC) Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SqBBYq

The Influence of ANS-6637 on Midazolam Pharmacokinetics in Healthy Volunteers

Condition:   Opioid Addiction Interventions:   Drug: MDZ;   Drug: ANS-6637 Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Dw0QOQ

Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet

Conditions:   Intervention;   Food Allergy;   Food Preferences;   Food Intolerance;   Diet Habit;   Diet Modification Intervention:   Behavioral: Multicomponent intervention Sponsors:   University Rovira i Virgili;   Diputació de Tarragona Not yet recruiting (Source: ClinicalTrials.gov)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2StbPmA

Retrospective Chart Review of Candida Fungemia

Condition:   Candida Intervention:   Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Active, not recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Dw0Pug

Safety Study of Hepatitis E Vaccine (HEV239) in Healthy US Adult Population

Conditions:   Hepatitis E;   Immunisation Interventions:   Biological: HEV 239;   Other: Placebo Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Srz7sV

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Conditions:   Pulmonary Invasive Mold Infections;   Pulmonary Invasive Aspergillosis Intervention:   Diagnostic Test: Non-Invasive Testing for PIMI Sponsors:   Duke University;   Children's Hospital of Philadelphia;   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2StJFaN

Study in Cat-Allergic Patients With Asthma to Evaluate the Efficacy of a Single Dose of REGN1908-1909 to Reduce Bronchoconstriction Upon Cat Allergen Challenge

Conditions:   Cat Allergy;   Mild Asthma Interventions:   Drug: REGN1908-1909;   Drug: Placebo Sponsor:   Regeneron Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SvMRmw

Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV

Condition:   HIV-1-infection Interventions:   Drug: Saline;   Drug: Lefitolimod;   Drug: 3BNC117 and 10-1074 Sponsors:   University of Aarhus;   Aalborg Universitetshospital;   Odense University Hospital;   Rigshospitalet, Denmark;   Hvidovre University Hospital;   The Peter Doherty Institute for Infection and Immunity;   University of Utah Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DvtpMi

The Influence of ANS-6637 on Midazolam Pharmacokinetics in Healthy Volunteers

Condition:   Opioid Addiction Interventions:   Drug: MDZ;   Drug: ANS-6637 Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Dw0QOQ

Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet

Conditions:   Intervention;   Food Allergy;   Food Preferences;   Food Intolerance;   Diet Habit;   Diet Modification Intervention:   Behavioral: Multicomponent intervention Sponsors:   University Rovira i Virgili;   Diputació de Tarragona Not yet recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2StbPmA

Retrospective Chart Review of Candida Fungemia

Condition:   Candida Intervention:   Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Active, not recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Dw0Pug

Safety Study of Hepatitis E Vaccine (HEV239) in Healthy US Adult Population

Conditions:   Hepatitis E;   Immunisation Interventions:   Biological: HEV 239;   Other: Placebo Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Srz7sV

Allergy UK Research and Development Nurse Project

Condition:   Allergy Intervention:   Other: Nurse Led Allergy Clinic Sponsors:   University of Edinburgh;   Allergy UK Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Dyspa9

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Conditions:   Pulmonary Invasive Mold Infections;   Pulmonary Invasive Aspergillosis Intervention:   Diagnostic Test: Non-Invasive Testing for PIMI Sponsors:   Duke University;   Children's Hospital of Philadelphia;   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2StJFaN

Minimally-invasive treatment option for early stage oral cancer reduces recovery time, improves survival

Source: www.newswise.com Author: Henry Ford Health System Henry Ford Cancer Institute is a leader in providing a minimally invasive procedure called […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2RUSbus

Aaaai 2019 aaaai 2019

Read clinically focused news coverage of key developments from AAAAI 2019Medscape Allergy & Immunology (Source: Medscape Today Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3reUC

Apple to launch Health Records eHR mobile app in U.S. Veterans Affairs deal

Apple (NSDQ:AAPL) said yesterday that it is preparing to launch its new Health Records mobile electronic health records feature for U.S. Veterans as part of a partnership with the U.S. Veteran's Health Administration. With the launch, veterans will be able to view their aggregated health records directly through the iHealth application on their iPhone devices, the tech giant said. Health record data will include allergies, conditions, immunizations, lab results, medications, procedures and vitals and will be displayed alongside other data, including fitness and active monitoring data from connected devices, the company said. The files will be encrypted and protected through the use of the device's passcode, Touch ID or Face ID biometric security verification, Apple said. "We hav...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SGOD3u

Minimally-invasive treatment option for early stage oral cancer reduces recovery time, improves survival

Source: www.newswise.com Author: Henry Ford Health System Henry Ford Cancer Institute is a leader in providing a minimally invasive procedure called […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2RUSbus

Aaaai 2019 aaaai 2019

Read clinically focused news coverage of key developments from AAAAI 2019Medscape Allergy & Immunology (Source: Medscape Today Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3reUC

Apple to launch Health Records eHR mobile app in U.S. Veterans Affairs deal

Apple (NSDQ:AAPL) said yesterday that it is preparing to launch its new Health Records mobile electronic health records feature for U.S. Veterans as part of a partnership with the U.S. Veteran's Health Administration. With the launch, veterans will be able to view their aggregated health records directly through the iHealth application on their iPhone devices, the tech giant said. Health record data will include allergies, conditions, immunizations, lab results, medications, procedures and vitals and will be displayed alongside other data, including fitness and active monitoring data from connected devices, the company said. The files will be encrypted and protected through the use of the device's passcode, Touch ID or Face ID biometric security verification, Apple said. "We hav...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SGOD3u

Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity

Nasal epithelial transcriptome is altered by the season. Birch pollen allergen immunotherapy recovers microbial community diversity and alters expression of allergy related genes.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SyvpO7

Interleukin-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

IL-4 receptor engagement in human neutrophils impairs their formation of extracellular traps and their in vitro and in vivo chemotaxis.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DypTAJ

High dietary fat intake induces a microbiota signature that promotes food allergy

Post-dieting microbiome alterations due to over indulgence of dietary fat increase susceptibility to experimental food allergy independent of obesity and metabolic derangements.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SyvjGf

Novel strategy for the prevention of recurrent hypersensitivity reactions to radiocontrast media based on skin testing

Hypersensitivity reaction to iodinated contrast media (ICM) is a persistent clinical issue with the increased use of computed tomography. With the evidences indicating underlying allergic mechanisms, there have been studies regarding the skin tests using ICM. This study aimed to evaluate intradermal skin test (IDT) as a tool for preventing recurrent hypersensitivity reactions to ICM in the previous reactors.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3u7Vl

Severe Obstructive Sleep Apnea with Imaged Carotid Plaque Significantly Associated with Systemic Inflammation

Persons with obstructive sleep apnea (OSA) are at heightened risk of myocardial infarction (MI) and stroke caused by adiposity and intermittent hypoxia which provoke proinflammatory cytokines to induce systemic/vascular inflammation resulting in endothelial dysfunction and development of atherosclerotic plaque. We aim to compare the levels of systemic inflammation between groups of patients having severe OSA with and without carotid artery calcified plaque (CACP+/CACP–) on their panoramic image (PI) as indexed by the neutrophil-lymphocyte ratio (NLR).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N1suYb

Nasal framework osteotomy: An innovative approach to manage an extremely long nose with meningoencephalocele

Nasal encephalocele is an uncommon congenital deformity in which the intracranial soft tissue components herniate through the skull base into the nasal cavity. Nasal encephaloceles may form large extracranial masses that necessitate early neurosurgical intervention. They can also cause deformation of the nasal bridge, causing elongation of the nose or severe orbital deformities. [1,2,3] The conventional approach to these cases includes obtaining wide and complicated intracranial access. [1,2,3,4] More recently, conservative techniques including transfacial incisions or intranasal endoscopic approaches have shown comparable outcomes.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SRXUG9

Evaluation of the effect of bio-resorbable plates and screws in the treatment of condylar fractures, assisted by digital preoperative planning

Although bio-resorbable materials have begun to be applied in the clinic, they are primarily used in children with fractures; thus, there are few reports of their application for treatment of condylar fractures. This study aimed to evaluate the effect of the application of bio-resorbable plates and screws for patients with condylar fractures, assisted by digital preoperative planning.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N1fn9u

Improved Outcomes of Orbital Reconstruction with Intraoperative Imaging and Rapid Prototyping

Rapid prototyping and intra-operative CT is increasingly employed in orbital reconstruction where placement of implants is indicated and accurate anatomic restoration is mandatory. The purpose of this study was to review the outcomes of orbital reconstructions at a single institution, and the influence of intraoperative CT and rapid prototyping on the rate of return to theatre.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SP4zk8

Capnography Detection Using Nasal Cannula is Superior to Modified Nasal Hood in an Open Airway System: a Randomized Controlled Trial

The nasal cannula and modified nasal hood are both methods used by oral and maxillofacial surgeons to detect expired carbon dioxide during procedural sedation in an open airway system. The purpose of this study is to compare the accuracy of the detection of expired carbon dioxide between the nasal cannula and modified nasal hood.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N1rxiF

The characteristics and cost of LeFort fractures: a review of 519 cases from a nationwide sample

The aims were to report the characteristics of LeFort fractures and to quantify the associated hospital costs.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SKxaaf

Surgery-first and Orthodontic-first approaches produce similar patterns of condylar displacement and remodeling in patients with skeletal class III malocclusion

s: Condylar displacement and remodeling are critically involved in occlusal and skeletal stability after orthognathic surgery. The aim of the present study was to characterize condylar displacement and surface remodeling after bimaxillary orthognathic surgery in adult patients with skeletal Class III malocclusion treated by surgery-first approach (SFA) or orthodontic-first approach (OFA).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3qJdc

What is the Effect of Treating Mandibular Fractures on Weight and Prealbumin?

Fracture healing relies on the body to coordinate an inflammatory and anabolic reaction to re-establish osseous union. While many factors affect this process, or even disrupt it, the role of the body's nutritional reserves is not well understood. The purpose of the present study was to describe the weight changes and to identify trends in laboratory values commonly used in nutritional assessment during mandibular fracture treatment.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEgMIz

Musculoskeletal Disorders in OMS: A Resident’s Perspective

Musculoskeletal disorders (MSDs) are a common issue among health care providers, and especially among dentists and surgeons. Dentists are most likely to be afflicted with MSDs, followed by surgeons.1 Current literature addressing MSDs in oral and maxillofacial surgeons (OMSs) is limited, but what data there is creates cause for concern. According to Ratzon et al, OMSs were almost twice as likely as general dentists to suffer from musculoskeletal pain. Further, OMSs had the highest human workload score, likely attributed to reduced movement (despite that dental assistance is more common in our specialty) and longer periods without breaks.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N30T9f

A comparison of immediate and delayed dental implant placement in head and neck surgery patients

Implant supported dental prostheses offer numerous benefits for patients following ablative procedures of the head and neck region including restoration of function, improved self-esteem and body satisfaction as well as overall quality of life. Increased experience is emerging with immediate placement of implants at the time of ablative surgery, contrasting the traditional delayed approach. We sought to identify variables impacting survival of osseointegrated dental implants in such patients, and to assess the impact of timing of implant insertion (immediate vs delayed) on the time until final prosthesis insertion.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEgEZB

Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity

Nasal epithelial transcriptome is altered by the season. Birch pollen allergen immunotherapy recovers microbial community diversity and alters expression of allergy related genes.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SyvpO7

Interleukin-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation

IL-4 receptor engagement in human neutrophils impairs their formation of extracellular traps and their in vitro and in vivo chemotaxis.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DypTAJ

High dietary fat intake induces a microbiota signature that promotes food allergy

Post-dieting microbiome alterations due to over indulgence of dietary fat increase susceptibility to experimental food allergy independent of obesity and metabolic derangements.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SyvjGf

Novel strategy for the prevention of recurrent hypersensitivity reactions to radiocontrast media based on skin testing

Hypersensitivity reaction to iodinated contrast media (ICM) is a persistent clinical issue with the increased use of computed tomography. With the evidences indicating underlying allergic mechanisms, there have been studies regarding the skin tests using ICM. This study aimed to evaluate intradermal skin test (IDT) as a tool for preventing recurrent hypersensitivity reactions to ICM in the previous reactors.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3u7Vl

Severe Obstructive Sleep Apnea with Imaged Carotid Plaque Significantly Associated with Systemic Inflammation

Persons with obstructive sleep apnea (OSA) are at heightened risk of myocardial infarction (MI) and stroke caused by adiposity and intermittent hypoxia which provoke proinflammatory cytokines to induce systemic/vascular inflammation resulting in endothelial dysfunction and development of atherosclerotic plaque. We aim to compare the levels of systemic inflammation between groups of patients having severe OSA with and without carotid artery calcified plaque (CACP+/CACP–) on their panoramic image (PI) as indexed by the neutrophil-lymphocyte ratio (NLR).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N1suYb

Nasal framework osteotomy: An innovative approach to manage an extremely long nose with meningoencephalocele

Nasal encephalocele is an uncommon congenital deformity in which the intracranial soft tissue components herniate through the skull base into the nasal cavity. Nasal encephaloceles may form large extracranial masses that necessitate early neurosurgical intervention. They can also cause deformation of the nasal bridge, causing elongation of the nose or severe orbital deformities. [1,2,3] The conventional approach to these cases includes obtaining wide and complicated intracranial access. [1,2,3,4] More recently, conservative techniques including transfacial incisions or intranasal endoscopic approaches have shown comparable outcomes.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SRXUG9

Evaluation of the effect of bio-resorbable plates and screws in the treatment of condylar fractures, assisted by digital preoperative planning

Although bio-resorbable materials have begun to be applied in the clinic, they are primarily used in children with fractures; thus, there are few reports of their application for treatment of condylar fractures. This study aimed to evaluate the effect of the application of bio-resorbable plates and screws for patients with condylar fractures, assisted by digital preoperative planning.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N1fn9u

Improved Outcomes of Orbital Reconstruction with Intraoperative Imaging and Rapid Prototyping

Rapid prototyping and intra-operative CT is increasingly employed in orbital reconstruction where placement of implants is indicated and accurate anatomic restoration is mandatory. The purpose of this study was to review the outcomes of orbital reconstructions at a single institution, and the influence of intraoperative CT and rapid prototyping on the rate of return to theatre.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SP4zk8

Capnography Detection Using Nasal Cannula is Superior to Modified Nasal Hood in an Open Airway System: a Randomized Controlled Trial

The nasal cannula and modified nasal hood are both methods used by oral and maxillofacial surgeons to detect expired carbon dioxide during procedural sedation in an open airway system. The purpose of this study is to compare the accuracy of the detection of expired carbon dioxide between the nasal cannula and modified nasal hood.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N1rxiF

The characteristics and cost of LeFort fractures: a review of 519 cases from a nationwide sample

The aims were to report the characteristics of LeFort fractures and to quantify the associated hospital costs.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SKxaaf

Surgery-first and Orthodontic-first approaches produce similar patterns of condylar displacement and remodeling in patients with skeletal class III malocclusion

s: Condylar displacement and remodeling are critically involved in occlusal and skeletal stability after orthognathic surgery. The aim of the present study was to characterize condylar displacement and surface remodeling after bimaxillary orthognathic surgery in adult patients with skeletal Class III malocclusion treated by surgery-first approach (SFA) or orthodontic-first approach (OFA).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3qJdc

What is the Effect of Treating Mandibular Fractures on Weight and Prealbumin?

Fracture healing relies on the body to coordinate an inflammatory and anabolic reaction to re-establish osseous union. While many factors affect this process, or even disrupt it, the role of the body's nutritional reserves is not well understood. The purpose of the present study was to describe the weight changes and to identify trends in laboratory values commonly used in nutritional assessment during mandibular fracture treatment.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEgMIz

Musculoskeletal Disorders in OMS: A Resident’s Perspective

Musculoskeletal disorders (MSDs) are a common issue among health care providers, and especially among dentists and surgeons. Dentists are most likely to be afflicted with MSDs, followed by surgeons.1 Current literature addressing MSDs in oral and maxillofacial surgeons (OMSs) is limited, but what data there is creates cause for concern. According to Ratzon et al, OMSs were almost twice as likely as general dentists to suffer from musculoskeletal pain. Further, OMSs had the highest human workload score, likely attributed to reduced movement (despite that dental assistance is more common in our specialty) and longer periods without breaks.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N30T9f

A comparison of immediate and delayed dental implant placement in head and neck surgery patients

Implant supported dental prostheses offer numerous benefits for patients following ablative procedures of the head and neck region including restoration of function, improved self-esteem and body satisfaction as well as overall quality of life. Increased experience is emerging with immediate placement of implants at the time of ablative surgery, contrasting the traditional delayed approach. We sought to identify variables impacting survival of osseointegrated dental implants in such patients, and to assess the impact of timing of implant insertion (immediate vs delayed) on the time until final prosthesis insertion.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SEgEZB

The role of customer service manual on workplace emotional burden in nationwide cross sectional study

We aim to discuss the overall effect of customer service manual (CSM) on service industry workers using Korean Working Condition Survey.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N1c2Y0

Effects of work-related factors on self-reported smoking among female workers in call centers: a cross-sectional study

This study conducted to investigate work-related factors in relation to smoking among women working in call centers in Gwangju, South Korea.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SMNmb0

The role of customer service manual on workplace emotional burden in nationwide cross sectional study

We aim to discuss the overall effect of customer service manual (CSM) on service industry workers using Korean Working Condition Survey.

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Effects of work-related factors on self-reported smoking among female workers in call centers: a cross-sectional study

This study conducted to investigate work-related factors in relation to smoking among women working in call centers in Gwangju, South Korea.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SMNmb0

Minimally-invasive treatment option for early stage oral cancer reduces recovery time, improves survival

Source: www.newswise.com Author: Henry Ford Health System Henry Ford Cancer Institute is a leader in providing a minimally invasive procedure called […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2RUSbus

Minimally-invasive treatment option for early stage oral cancer reduces recovery time, improves survival

Source: www.newswise.com Author: Henry Ford Health System Henry Ford Cancer Institute is a leader in providing a minimally invasive procedure called […]

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2RUSbus

Trending: Need a Breath of Fresh Air? Hotels to the Rescue

More hotels are adding air purifiers and filters to their guest rooms, either because the outside air is prone to smoke or pollution, or because guests demand them for health reasons. (Source: NYT Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

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Trending: Need a Breath of Fresh Air? Hotels to the Rescue

More hotels are adding air purifiers and filters to their guest rooms, either because the outside air is prone to smoke or pollution, or because guests demand them for health reasons. (Source: NYT Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

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Non Familial Cherubism: A Case Report

AbstractCherubism might occur in solitary cases or in several members of the family, often in many generations. Treatment depends on the clinical course of the disease. The reported case is an example of solitary sporadic occurrence within a family, which is a less documented condition in the literature. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)

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Development of an Experimental System “Computer-Aided Diagnosis in Neurotology (CADINO)” for Vertigo

AbstractComputer-based medical diagnosis expert systems, when used by clinicians, familiar with the limitations of the system, were found both accurate and educationally helpful. Vertigo is one of the most common complaints of the patients and the specialists who manage these patients are not easily available. Diagnostic expert system can help clinicians including general practitioners in providing reasonable diagnostic suggestions while dealing with patients with vertigo/dizziness when the specialist doctors are not available. To provide an understanding about the method of making an expert system "Computer-Aided Diagnosis in Neurotology (CADINO)" for dizzy patients and highlight its potential uses. CADINO, developed during this original research project, is an expert computer program...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TRRuUJ

Non Familial Cherubism: A Case Report

AbstractCherubism might occur in solitary cases or in several members of the family, often in many generations. Treatment depends on the clinical course of the disease. The reported case is an example of solitary sporadic occurrence within a family, which is a less documented condition in the literature. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BxuxPf

Development of an Experimental System “Computer-Aided Diagnosis in Neurotology (CADINO)” for Vertigo

AbstractComputer-based medical diagnosis expert systems, when used by clinicians, familiar with the limitations of the system, were found both accurate and educationally helpful. Vertigo is one of the most common complaints of the patients and the specialists who manage these patients are not easily available. Diagnostic expert system can help clinicians including general practitioners in providing reasonable diagnostic suggestions while dealing with patients with vertigo/dizziness when the specialist doctors are not available. To provide an understanding about the method of making an expert system "Computer-Aided Diagnosis in Neurotology (CADINO)" for dizzy patients and highlight its potential uses. CADINO, developed during this original research project, is an expert computer program...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TRRuUJ

A Flexible Suspension Technique of Blepharoplasty: Clinical Application and Comparison with Traditional Technique

Abstract

Background

Double-eyelid blepharoplasty is one of the most popular aesthetic surgeries in China. But the traditional method produces a hidebound double eyelid due to its rigid suturing between the skin and the tarsus. The authors of this article concluded a novel technique of "flexible suspension technique" compared with traditional blepharoplasty which is considered as a "rigid fixation technique."

Methods

This is a retrospective study of two groups of 100 Chinese Han females, on whom double-eyelid blepharoplasty was performed, 50 cases by "flexible suspension technique" and the other 50 by "rigid fixation technique." The basic procedure of "flexible suspension technique" is suturing the orbicularis oculi muscle to the septal extension. Thus, the surgical connection between skin and tarsus is flexible. The surgical results were evaluated and compared using the Global Aesthetic Improvement Scale and Visual Analogue Scale/Score.

Results

The "very much improved" rate in the "flexible suspension technique" group was higher than that in the "rigid fixation technique" group (p < 0.05). Postoperative appearances of the "flexible suspension technique" group were also better than the "rigid fixation technique" group with less edema (p < 0.05) and slighter incision scars (p < 0.05). However, the incidences of asymmetry and fold loss were higher in the "flexible suspension technique" group (p < 0.05).

Conclusion

The flexible suspension technique blepharoplasty can obtain a more natural appearance and has less adverse effects and shorter recovery time.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BtSQh2

A Flexible Suspension Technique of Blepharoplasty: Clinical Application and Comparison with Traditional Technique

Abstract

Background

Double-eyelid blepharoplasty is one of the most popular aesthetic surgeries in China. But the traditional method produces a hidebound double eyelid due to its rigid suturing between the skin and the tarsus. The authors of this article concluded a novel technique of "flexible suspension technique" compared with traditional blepharoplasty which is considered as a "rigid fixation technique."

Methods

This is a retrospective study of two groups of 100 Chinese Han females, on whom double-eyelid blepharoplasty was performed, 50 cases by "flexible suspension technique" and the other 50 by "rigid fixation technique." The basic procedure of "flexible suspension technique" is suturing the orbicularis oculi muscle to the septal extension. Thus, the surgical connection between skin and tarsus is flexible. The surgical results were evaluated and compared using the Global Aesthetic Improvement Scale and Visual Analogue Scale/Score.

Results

The "very much improved" rate in the "flexible suspension technique" group was higher than that in the "rigid fixation technique" group (p < 0.05). Postoperative appearances of the "flexible suspension technique" group were also better than the "rigid fixation technique" group with less edema (p < 0.05) and slighter incision scars (p < 0.05). However, the incidences of asymmetry and fold loss were higher in the "flexible suspension technique" group (p < 0.05).

Conclusion

The flexible suspension technique blepharoplasty can obtain a more natural appearance and has less adverse effects and shorter recovery time.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BtSQh2

From intensive care unit to operating room: what about the transition of care of liver transplanted patients?

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3MhGz

Practical Perioperative Transoesophageal Echocardiography, 3rd Edition

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SOLgYc

Mechanical Ventilation: Physiology and Practice, Second Edition

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3hfP1

Trending: Need a Breath of Fresh Air? Hotels to the Rescue

More hotels are adding air purifiers and filters to their guest rooms, either because the outside air is prone to smoke or pollution, or because guests demand them for health reasons. (Source: NYT Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2S1EWZa

From intensive care unit to operating room: what about the transition of care of liver transplanted patients?

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3MhGz

Practical Perioperative Transoesophageal Echocardiography, 3rd Edition

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SOLgYc

Mechanical Ventilation: Physiology and Practice, Second Edition

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2N3hfP1

Trending: Need a Breath of Fresh Air? Hotels to the Rescue

More hotels are adding air purifiers and filters to their guest rooms, either because the outside air is prone to smoke or pollution, or because guests demand them for health reasons. (Source: NYT Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

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Immunology Interest Group Seminar Series - " Trained Immunity: A Memory for Innate Host Defense ” - Mihai Net (Nijmegen Medical Center, The Netherlands)

Date: Wednesday, 02 13, 2019; Speaker: Mihai Netea; Building: Building 10 (Clinical Center); Lipsett Auditorium (Source: NIH Calendar of Events)

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Immunology Interest Group Seminar Series - " Trained Immunity: A Memory for Innate Host Defense ” - Mihai Net (Nijmegen Medical Center, The Netherlands)

Date: Wednesday, 02 13, 2019; Speaker: Mihai Netea; Building: Building 10 (Clinical Center); Lipsett Auditorium (Source: NIH Calendar of Events)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

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The Efficacy of Different Volumes on Ultrasound-Guided Type-I Pectoral Nerve Block for Postoperative Analgesia After Subpectoral Breast Augmentation: A Prospective, Randomized, Controlled Study

Abstract

Background

PECS type-1 block, a US-guided superficial interfacial block, provides effective analgesia after breast surgery. Aesthetic breast augmentation is one of the most common surgical procedures in plastic surgery. Subpectoral prostheses cause severe pain. The aim of this study was to investigate the effect of different volumes of the solution on the efficacy of PECS type-I block for postoperative analgesia after breast augmentation surgery.

Methods

Ninety ASA status I–II female patients aged between 18 and 65 years who scheduled breast augmentation surgery under general anesthesia were included in this study. The patients were randomly divided into three groups of 30 patients each (Group 20 = 20 ml of anaesthetic solution, Group 30 = 30 ml anaesthetic solution, and Group K = Control group). Postoperative assessment was performed using the VAS score. The VAS scores were recorded postoperatively at 1, 2, 4, 8, 16 and 24 h.

Results

Fentanyl consumption was statistically significantly lower in Group 20 and Group 30 compared to the Control group (p < 0.05). There was no statistically significant difference in fentanyl consumption between Group 20 and Group 30. The right and left VAS scores were statistically significantly lower in Groups 20 and 30 than in the Control group (p < 0.05). There was no statistical difference in terms of VAS scores between Group 20 and Group 30. The use of rescue analgesia was statistically lower in Groups 20 and 30.

Conclusions

PECS type-1 block using 20 ml of 0.25% bupivacaine can provide effective analgesia after breast augmentation surgery.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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A Flexible Suspension Technique of Blepharoplasty: Clinical Application and Comparison with Traditional Technique

Abstract

Background

Double-eyelid blepharoplasty is one of the most popular aesthetic surgeries in China. But the traditional method produces a hidebound double eyelid due to its rigid suturing between the skin and the tarsus. The authors of this article concluded a novel technique of "flexible suspension technique" compared with traditional blepharoplasty which is considered as a "rigid fixation technique."

Methods

This is a retrospective study of two groups of 100 Chinese Han females, on whom double-eyelid blepharoplasty was performed, 50 cases by "flexible suspension technique" and the other 50 by "rigid fixation technique." The basic procedure of "flexible suspension technique" is suturing the orbicularis oculi muscle to the septal extension. Thus, the surgical connection between skin and tarsus is flexible. The surgical results were evaluated and compared using the Global Aesthetic Improvement Scale and Visual Analogue Scale/Score.

Results

The "very much improved" rate in the "flexible suspension technique" group was higher than that in the "rigid fixation technique" group (p < 0.05). Postoperative appearances of the "flexible suspension technique" group were also better than the "rigid fixation technique" group with less edema (p < 0.05) and slighter incision scars (p < 0.05). However, the incidences of asymmetry and fold loss were higher in the "flexible suspension technique" group (p < 0.05).

Conclusion

The flexible suspension technique blepharoplasty can obtain a more natural appearance and has less adverse effects and shorter recovery time.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BtSQh2

The Efficacy of Different Volumes on Ultrasound-Guided Type-I Pectoral Nerve Block for Postoperative Analgesia After Subpectoral Breast Augmentation: A Prospective, Randomized, Controlled Study

Abstract

Background

PECS type-1 block, a US-guided superficial interfacial block, provides effective analgesia after breast surgery. Aesthetic breast augmentation is one of the most common surgical procedures in plastic surgery. Subpectoral prostheses cause severe pain. The aim of this study was to investigate the effect of different volumes of the solution on the efficacy of PECS type-I block for postoperative analgesia after breast augmentation surgery.

Methods

Ninety ASA status I–II female patients aged between 18 and 65 years who scheduled breast augmentation surgery under general anesthesia were included in this study. The patients were randomly divided into three groups of 30 patients each (Group 20 = 20 ml of anaesthetic solution, Group 30 = 30 ml anaesthetic solution, and Group K = Control group). Postoperative assessment was performed using the VAS score. The VAS scores were recorded postoperatively at 1, 2, 4, 8, 16 and 24 h.

Results

Fentanyl consumption was statistically significantly lower in Group 20 and Group 30 compared to the Control group (p < 0.05). There was no statistically significant difference in fentanyl consumption between Group 20 and Group 30. The right and left VAS scores were statistically significantly lower in Groups 20 and 30 than in the Control group (p < 0.05). There was no statistical difference in terms of VAS scores between Group 20 and Group 30. The use of rescue analgesia was statistically lower in Groups 20 and 30.

Conclusions

PECS type-1 block using 20 ml of 0.25% bupivacaine can provide effective analgesia after breast augmentation surgery.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2WVFx20

A Flexible Suspension Technique of Blepharoplasty: Clinical Application and Comparison with Traditional Technique

Abstract

Background

Double-eyelid blepharoplasty is one of the most popular aesthetic surgeries in China. But the traditional method produces a hidebound double eyelid due to its rigid suturing between the skin and the tarsus. The authors of this article concluded a novel technique of "flexible suspension technique" compared with traditional blepharoplasty which is considered as a "rigid fixation technique."

Methods

This is a retrospective study of two groups of 100 Chinese Han females, on whom double-eyelid blepharoplasty was performed, 50 cases by "flexible suspension technique" and the other 50 by "rigid fixation technique." The basic procedure of "flexible suspension technique" is suturing the orbicularis oculi muscle to the septal extension. Thus, the surgical connection between skin and tarsus is flexible. The surgical results were evaluated and compared using the Global Aesthetic Improvement Scale and Visual Analogue Scale/Score.

Results

The "very much improved" rate in the "flexible suspension technique" group was higher than that in the "rigid fixation technique" group (p < 0.05). Postoperative appearances of the "flexible suspension technique" group were also better than the "rigid fixation technique" group with less edema (p < 0.05) and slighter incision scars (p < 0.05). However, the incidences of asymmetry and fold loss were higher in the "flexible suspension technique" group (p < 0.05).

Conclusion

The flexible suspension technique blepharoplasty can obtain a more natural appearance and has less adverse effects and shorter recovery time.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BtSQh2

Implementing Shared, Standardized Imaging Protocols to Improve Cross-Enterprise Workflow and Quality

Abstract

Value-based imaging requires appropriate utilization and the delivery of consistently high-quality imaging at an acceptable cost. Challenges include developing standardized imaging protocols, ensuring consistent application by technologists, and monitoring quality. These challenges increase as enterprises grow in geographical extent and complexity through mergers or partnerships. Our imaging enterprise includes a university hospital and clinic system, a large county hospital and healthcare system, and a pediatric hospital and health system. Studies across the three systems are interpreted by one large academic radiology group with expertise in various subspecialties. Our goals were as follows: (1) Standardize imaging protocols; (2) adapt the imaging protocols to specific modalities and available equipment; and (3) disseminate this knowledge across all of the sites of care. Our approach involved three components: (1) facilitation of imaging protocol definition across subspecialty radiologist teams; (2) creation of a database which links the clinical imaging protocols to the scanner/machine specific acquisition protocols; and (3) delivery of a protocol library and updates to all users regardless of location. We successfully instituted a process for the development, implementation, and delivery of standardized imaging protocols in a complex, multi-institutional healthcare system. Key elements for success include (1) a Project Champion who is able to articulate the importance of protocol standardization in improving the quality of patient care, (2) strong, effective modality-specific operational committees, (3) a Project Lead to manage the process efficiently, and (4) an electronic publishing of the protocol database to facilitate ease of access and use.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DBGxPR

Breast Cancer Classification from Histopathological Images with Inception Recurrent Residual Convolutional Neural Network

Abstract

The Deep Convolutional Neural Network (DCNN) is one of the most powerful and successful deep learning approaches. DCNNs have already provided superior performance in different modalities of medical imaging including breast cancer classification, segmentation, and detection. Breast cancer is one of the most common and dangerous cancers impacting women worldwide. In this paper, we have proposed a method for breast cancer classification with the Inception Recurrent Residual Convolutional Neural Network (IRRCNN) model. The IRRCNN is a powerful DCNN model that combines the strength of the Inception Network (Inception-v4), the Residual Network (ResNet), and the Recurrent Convolutional Neural Network (RCNN). The IRRCNN shows superior performance against equivalent Inception Networks, Residual Networks, and RCNNs for object recognition tasks. In this paper, the IRRCNN approach is applied for breast cancer classification on two publicly available datasets including BreakHis and Breast Cancer (BC) classification challenge 2015. The experimental results are compared against the existing machine learning and deep learning–based approaches with respect to image-based, patch-based, image-level, and patient-level classification. The IRRCNN model provides superior classification performance in terms of sensitivity, area under the curve (AUC), the ROC curve, and global accuracy compared to existing approaches for both datasets.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2St0L8T

Lung Nodule Manager App Review

Abstract

Intermediate lung nodules are frequently discovered in CT imaging as either incidental or part of cancer screening. The Lung Nodule Manager allows for a quick retrieval of guidelines by physicians and health care professionals to determine the proper management and follow-up for patients.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DBGiEr

Anthropometer3D: Automatic Multi-Slice Segmentation Software for the Measurement of Anthropometric Parameters from CT of PET/CT

Abstract

Anthropometric parameters like muscle body mass (MBM), fat body mass (FBM), lean body mass (LBM), visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT) are used in oncology. Our aim was to develop and evaluate the software Anthropometer3D measuring these anthropometric parameters on the CT of PET/CT. This software performs a multi-atlas segmentation of CT of PET/CT with extrapolation coefficients for the body parts beyond the usual acquisition range (from the ischia to the eyes). The multi-atlas database is composed of 30 truncated CTs manually segmented to isolate three types of voxels (muscle, fat, and visceral fat). To evaluate Anthropomer3D, a leave-one-out cross-validation was performed to measure MBM, FBM, LBM, VAT, and SAT. The reference standard was based on the manual segmentation of the corresponding whole-body CT. A manual segmentation of one CT slice at level L3 was also used. Correlations were analyzed using Dice coefficient, intra-class coefficient correlation (ICC), and Bland–Altman plot. The population was heterogeneous (sex ratio 1:1; mean age 57 years old [min 23; max 74]; mean BMI 27 kg/m² [min 18; max 40]). Dice coefficients between reference standard and Anthropometer3D were excellent (mean+/-SD): muscle 0.95 ± 0.02, fat 1.00 ± 0.01, and visceral fat 0.97 ± 0.02. The ICC was almost perfect (minimal value of 95% CI of 0.97). All Bland–Altman plot values (mean difference, 95% CI and slopes) were better for Anthropometer3D compared to L3 level segmentation. Anthropometer3D allows multiple anthropometric measurements based on an automatic multi-slice segmentation. It is more precise than estimates using L3 level segmentation.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2St0DGr

Glaucoma Detection from Retinal Images Using Statistical and Textural Wavelet Features

Abstract

Glaucoma is a silent progressive eye disease that is among the leading causes of irreversible blindness. Early detection and proper treatment of glaucoma can limit severe vision impairments associated with advanced stages of the disease. Periodic automatic screening can help in the early detection of glaucoma while reducing the workload on expert ophthalmologists. In this work, a wavelet-based glaucoma detection algorithm is proposed for real-time screening systems. A combination of wavelet-based statistical and textural features computed from the detected optic disc region is used to determine whether a retinal image is healthy or glaucomatous. Two public datasets having different resolutions were considered in the performance analysis of the proposed algorithm. An accuracy of 96.7% and area under receiver operating curve (AUC) of 94.7% were achieved for the high-resolution dataset. Analysis of the wavelet-based statistical and textural features using three different methods showed their relevance for glaucoma detection. Furthermore, the proposed algorithm is shown to be suitable for real-time applications as it requires less than 3 s for processing the high-resolution retinal images.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DBG2Ft

Implementing Shared, Standardized Imaging Protocols to Improve Cross-Enterprise Workflow and Quality

Abstract

Value-based imaging requires appropriate utilization and the delivery of consistently high-quality imaging at an acceptable cost. Challenges include developing standardized imaging protocols, ensuring consistent application by technologists, and monitoring quality. These challenges increase as enterprises grow in geographical extent and complexity through mergers or partnerships. Our imaging enterprise includes a university hospital and clinic system, a large county hospital and healthcare system, and a pediatric hospital and health system. Studies across the three systems are interpreted by one large academic radiology group with expertise in various subspecialties. Our goals were as follows: (1) Standardize imaging protocols; (2) adapt the imaging protocols to specific modalities and available equipment; and (3) disseminate this knowledge across all of the sites of care. Our approach involved three components: (1) facilitation of imaging protocol definition across subspecialty radiologist teams; (2) creation of a database which links the clinical imaging protocols to the scanner/machine specific acquisition protocols; and (3) delivery of a protocol library and updates to all users regardless of location. We successfully instituted a process for the development, implementation, and delivery of standardized imaging protocols in a complex, multi-institutional healthcare system. Key elements for success include (1) a Project Champion who is able to articulate the importance of protocol standardization in improving the quality of patient care, (2) strong, effective modality-specific operational committees, (3) a Project Lead to manage the process efficiently, and (4) an electronic publishing of the protocol database to facilitate ease of access and use.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DBGxPR

Breast Cancer Classification from Histopathological Images with Inception Recurrent Residual Convolutional Neural Network

Abstract

The Deep Convolutional Neural Network (DCNN) is one of the most powerful and successful deep learning approaches. DCNNs have already provided superior performance in different modalities of medical imaging including breast cancer classification, segmentation, and detection. Breast cancer is one of the most common and dangerous cancers impacting women worldwide. In this paper, we have proposed a method for breast cancer classification with the Inception Recurrent Residual Convolutional Neural Network (IRRCNN) model. The IRRCNN is a powerful DCNN model that combines the strength of the Inception Network (Inception-v4), the Residual Network (ResNet), and the Recurrent Convolutional Neural Network (RCNN). The IRRCNN shows superior performance against equivalent Inception Networks, Residual Networks, and RCNNs for object recognition tasks. In this paper, the IRRCNN approach is applied for breast cancer classification on two publicly available datasets including BreakHis and Breast Cancer (BC) classification challenge 2015. The experimental results are compared against the existing machine learning and deep learning–based approaches with respect to image-based, patch-based, image-level, and patient-level classification. The IRRCNN model provides superior classification performance in terms of sensitivity, area under the curve (AUC), the ROC curve, and global accuracy compared to existing approaches for both datasets.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2St0L8T

Lung Nodule Manager App Review

Abstract

Intermediate lung nodules are frequently discovered in CT imaging as either incidental or part of cancer screening. The Lung Nodule Manager allows for a quick retrieval of guidelines by physicians and health care professionals to determine the proper management and follow-up for patients.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DBGiEr

Anthropometer3D: Automatic Multi-Slice Segmentation Software for the Measurement of Anthropometric Parameters from CT of PET/CT

Abstract

Anthropometric parameters like muscle body mass (MBM), fat body mass (FBM), lean body mass (LBM), visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT) are used in oncology. Our aim was to develop and evaluate the software Anthropometer3D measuring these anthropometric parameters on the CT of PET/CT. This software performs a multi-atlas segmentation of CT of PET/CT with extrapolation coefficients for the body parts beyond the usual acquisition range (from the ischia to the eyes). The multi-atlas database is composed of 30 truncated CTs manually segmented to isolate three types of voxels (muscle, fat, and visceral fat). To evaluate Anthropomer3D, a leave-one-out cross-validation was performed to measure MBM, FBM, LBM, VAT, and SAT. The reference standard was based on the manual segmentation of the corresponding whole-body CT. A manual segmentation of one CT slice at level L3 was also used. Correlations were analyzed using Dice coefficient, intra-class coefficient correlation (ICC), and Bland–Altman plot. The population was heterogeneous (sex ratio 1:1; mean age 57 years old [min 23; max 74]; mean BMI 27 kg/m² [min 18; max 40]). Dice coefficients between reference standard and Anthropometer3D were excellent (mean+/-SD): muscle 0.95 ± 0.02, fat 1.00 ± 0.01, and visceral fat 0.97 ± 0.02. The ICC was almost perfect (minimal value of 95% CI of 0.97). All Bland–Altman plot values (mean difference, 95% CI and slopes) were better for Anthropometer3D compared to L3 level segmentation. Anthropometer3D allows multiple anthropometric measurements based on an automatic multi-slice segmentation. It is more precise than estimates using L3 level segmentation.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2St0DGr

Glaucoma Detection from Retinal Images Using Statistical and Textural Wavelet Features

Abstract

Glaucoma is a silent progressive eye disease that is among the leading causes of irreversible blindness. Early detection and proper treatment of glaucoma can limit severe vision impairments associated with advanced stages of the disease. Periodic automatic screening can help in the early detection of glaucoma while reducing the workload on expert ophthalmologists. In this work, a wavelet-based glaucoma detection algorithm is proposed for real-time screening systems. A combination of wavelet-based statistical and textural features computed from the detected optic disc region is used to determine whether a retinal image is healthy or glaucomatous. Two public datasets having different resolutions were considered in the performance analysis of the proposed algorithm. An accuracy of 96.7% and area under receiver operating curve (AUC) of 94.7% were achieved for the high-resolution dataset. Analysis of the wavelet-based statistical and textural features using three different methods showed their relevance for glaucoma detection. Furthermore, the proposed algorithm is shown to be suitable for real-time applications as it requires less than 3 s for processing the high-resolution retinal images.

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The Efficacy of Different Volumes on Ultrasound-Guided Type-I Pectoral Nerve Block for Postoperative Analgesia After Subpectoral Breast Augmentation: A Prospective, Randomized, Controlled Study

Abstract

Background

PECS type-1 block, a US-guided superficial interfacial block, provides effective analgesia after breast surgery. Aesthetic breast augmentation is one of the most common surgical procedures in plastic surgery. Subpectoral prostheses cause severe pain. The aim of this study was to investigate the effect of different volumes of the solution on the efficacy of PECS type-I block for postoperative analgesia after breast augmentation surgery.

Methods

Ninety ASA status I–II female patients aged between 18 and 65 years who scheduled breast augmentation surgery under general anesthesia were included in this study. The patients were randomly divided into three groups of 30 patients each (Group 20 = 20 ml of anaesthetic solution, Group 30 = 30 ml anaesthetic solution, and Group K = Control group). Postoperative assessment was performed using the VAS score. The VAS scores were recorded postoperatively at 1, 2, 4, 8, 16 and 24 h.

Results

Fentanyl consumption was statistically significantly lower in Group 20 and Group 30 compared to the Control group (p < 0.05). There was no statistically significant difference in fentanyl consumption between Group 20 and Group 30. The right and left VAS scores were statistically significantly lower in Groups 20 and 30 than in the Control group (p < 0.05). There was no statistical difference in terms of VAS scores between Group 20 and Group 30. The use of rescue analgesia was statistically lower in Groups 20 and 30.

Conclusions

PECS type-1 block using 20 ml of 0.25% bupivacaine can provide effective analgesia after breast augmentation surgery.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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Manual volume delivery via Frova Intubating Introducer: a bench research study

Abstract

Purpose

Oxygen delivery through a Frova Intubating Introducer may be life-saving, and gas flow characteristics through this device have been described. Nevertheless, the feasibility of using a self-inflating resuscitation bag to deliver air or oxygen through this device has not been assessed. We compared volumes of air delivered and peak pressures generated with normal and maximal bimanual compression of a self-inflating resuscitation bag connected to a 70 cm Frova Intubating Introducer.

Methods

In this bench research study, the proximal end of the 14-F Frova Intubating Introducer was connected to the self-inflating resuscitation bag, and the distal end was connected to a flow analyzer fitted with an adult test lung. Thirty-five anesthesia health care providers (staff/trainees) squeezed the self-inflating resuscitation bag with three normal and three maximal bimanual compressions. Endpoints of interest included the delivered volume of air and generated peak pressure.

Results

Normal bimanual compression resulted in a smaller mean (standard deviation) volume of air and peak pressure compared with maximal bimanual compression [554 (131) vs 955 mL (121); mean difference − 400.4; 95% confidence interval [CI], − 441.8 to − 359.0; P < 0.001; and 22.0 (3.4) vs 41.8 cmH₂O (13.3); mean difference − 19.7; 95% CI, − 23.5 to − 15.9; P < 0.001, respectively].

Conclusion

Clinically useful, life-sustaining volumes of air can be delivered using normal and maximal bimanual compression of a self-inflating resuscitation bag connected to a 70 cm Frova Intubating Introducer.

Trial registration

www.clinicaltrials.gov (NCT02786355); registered 27 January, 2016.

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