Condition: Peanut Allergy Intervention: Sponsor: University Hospital, Montpellier Recruiting (Source: ClinicalTrials.gov)
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Conditions: Chlamydial Infection; Gonococcal Infection; Trichomoniasis Intervention: Device: Click Device Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2XkMz0u
(Source: The Doctors Lounge - Oncology)
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Infants exposed to a diverse environment and animals have bacteria in their gut microbiomes that protect against atopy and asthma, new research shows, offering clues to future treatments.Medscape Medical News (Source: Medscape Medical News Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Xp7Juh
National Allergy Center's two locations in California are treating people's food allergies by gradually exposing them to things they can't eat. The unapproved method is promising but dangerous. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Sopl5P
(MedPage Today) -- Reduced need for surgery, systemic steroids (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IDfTMi
(MedPage Today) -- No safety concerns in phase I studies (Source: MedPage Today Allergy)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
B&G Foods announced today it is voluntarily recalling 1,280 cases of a single date code of 40 oz. Victoria Marinara Sauce, with a "best by" date of 03/06/2022, after learning that the product may contain cashew allergens that are not declared on the product's ingredient statement. People who have an allergy or severe sensitivity to cashew run the risk of serious or life-threatening allergic reaction if they consume this product. There is no health risk associated with this product for individuals without an allergy to tree nuts. (Source: Food and Drug Administration)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IEmh65
Condition: Peanut Allergy Intervention: Sponsor: University Hospital, Montpellier Recruiting (Source: ClinicalTrials.gov)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Conditions: Chlamydial Infection; Gonococcal Infection; Trichomoniasis Intervention: Device: Click Device Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2XkMz0u
(Source: The Doctors Lounge - Oncology)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Infants exposed to a diverse environment and animals have bacteria in their gut microbiomes that protect against atopy and asthma, new research shows, offering clues to future treatments.Medscape Medical News (Source: Medscape Medical News Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Xp7Juh
National Allergy Center's two locations in California are treating people's food allergies by gradually exposing them to things they can't eat. The unapproved method is promising but dangerous. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Sopl5P
(MedPage Today) -- Reduced need for surgery, systemic steroids (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IDfTMi
(MedPage Today) -- No safety concerns in phase I studies (Source: MedPage Today Allergy)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
B&G Foods announced today it is voluntarily recalling 1,280 cases of a single date code of 40 oz. Victoria Marinara Sauce, with a "best by" date of 03/06/2022, after learning that the product may contain cashew allergens that are not declared on the product's ingredient statement. People who have an allergy or severe sensitivity to cashew run the risk of serious or life-threatening allergic reaction if they consume this product. There is no health risk associated with this product for individuals without an allergy to tree nuts. (Source: Food and Drug Administration)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IEmh65
Conditions: Deafness; Sensoneural Single Sided; Conductive Hearing Loss; Mixed Hearing Loss Intervention: Device: Investigational device - Sound Processor Sponsor: Cochlear Bone Anchored Solutions Recruiting (Source: ClinicalTrials.gov)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2GZ7XTk
Condition: Eustachian Tube Dysfunction Interventions: Device: EarPopper; Device: Tympanometry; Device: Tubomanometry Sponsors: University of Pittsburgh; National Institute on Deafness and Other Communication Disorders (NIDCD) Not yet recruiting (Source: ClinicalTrials.gov)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2tCYNE0
Conditions: Deafness; Sensoneural Single Sided; Conductive Hearing Loss; Mixed Hearing Loss Intervention: Device: Investigational device - Sound Processor Sponsor: Cochlear Bone Anchored Solutions Recruiting (Source: ClinicalTrials.gov)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2GZ7XTk
Condition: Eustachian Tube Dysfunction Interventions: Device: EarPopper; Device: Tympanometry; Device: Tubomanometry Sponsors: University of Pittsburgh; National Institute on Deafness and Other Communication Disorders (NIDCD) Not yet recruiting (Source: ClinicalTrials.gov)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2tCYNE0
(Source: The Doctors Lounge - Oncology)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Updated Date: Feb 25, 2019 EST (Source: DailyMed Drug Label Updates)
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Updated Date: Feb 20, 2019 EST (Source: DailyMed Drug Label Updates)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2XoI2Kv
(Source: The Doctors Lounge - Oncology)
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Updated Date: Feb 25, 2019 EST (Source: DailyMed Drug Label Updates)
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We demonstrate that blocking the mevalonate pathway and protein prenylation in human monocytes leads to enhanced activity of an NLRP3-dependent, but not Pyrin-dependent, inflammasome, suggesting a prominent role for NLRP3 in the pathogenesis of mevalonate kinase deficiency. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U4rV2M
An increasing number of cases of alpha-gal allergy (AGA) have been reported in the U.S. and in several parts of the world over the past decade. In the U.S., cases of AGA are most often reported in the southeastern region, overlapping with the distribution of the Lone Star tick. However, epidemiological and time trend studies on AGA are lacking. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U4rLbG
Episodic angioedema with eosinophilia, or Gleich syndrome, is a rare disorder characterized by periodic episodes of angioedema and leukocytosis with marked eosinophilia. Symptoms resolve spontaneously or are treated with corticosteroids as first-line therapy. Treatment of patients unresponsive to or dependent on corticosteroids is poorly defined. Several rheumatologic diseases, including rheumatoid arthritis (RA), can also present with elevated eosinophilia in blood or tissue. Here we present a case of steroid-dependent Gleich syndrome complicated by concurrent rheumatoid arthritis. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BU81jJ
The effects of Omalizumab on food allergy thresholds are poorly studied out of the context of Oral Immunotherapy. This real life study aims to assess the effect of Omalizumab on food tolerance in children treated for severe asthma. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BQfXmc
CD300a is an inhibitory receptor expressed on mast cells (MCs) and eosinophils (Eos), cardinal effector cells of allergic inflammation (AI). Its expression and role in the resolution of AI, however, are still not characterized. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U8oZlH
A 2016 AAAAI position statement recommended routine evaluation of beta-lactam allergies due to the burden of pervasive mislabeled allergies. This quality improvement study implemented strategies to expedite evaluation at Rady Children 's Hospital. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BRFuLY
Glucocorticoids (GC) remain the most commonly used therapy for eosinophil-associated disorders (EAD). Prolonged treatment is associated with significant side effects and resistance that commonly lead to drug discontinuation. Whereas rapid disappearance of blood eosinophils following a single dose of GC is characteristic, the mechanisms by which this occurs is unknown. To explore this, we developed a novel radiolabeling technique to track eosinophils following GC administration in vivo in a rhesus macaque model. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U8AKbC
Allergen-specific immunotherapy (AIT) is the only curative option of allergic diseases. However, a few proportions of allergic patients take AIT because of undesirable perspectives. In this multicenter cross-sectional study, we aimed to explore the patients ' and doctors' perspectives of AIT through personal survey. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BVdCGu
We reviewed authors ' gender in The Journal of Allergy and Clinical Immunology (JACI) and Annals of Allergy, Asthma and Immunology (Annals) from 1997-2007 to determine frequency and patterns of publication by gender. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BWLUcx
This study describes the current prevalence, severity, and determinants of sesame allergy among the U.S. population. It was hypothesized that current prevalence rates of sesame allergy are comparable to rates of other food allergies for which labeling is legally mandated. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U4fIuF
Disruption of epidermal tight junctions (TJs), is thought to promote immunological responses to epicutaneous antigens. The Atopic Dermatitis Research Network performed a cross-sectional study to visualize TJs and Langerhans cells (LCs) in the skin of atopic dermatitis (AD) and nonatopic (NA) controls. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BQHFiQ
The measurement of drug-induced interferon-gamma releasing cells is another option to identify the culprit drug in severe cutaneous adverse reactions (SCARs) since drug provocation is contraindicated. However, its sensitivity is rather limited since other cytokines also play a role in pathogenesis of drug hypersensitivity. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U7kkAj
Women have increased prevalence of severe asthma and increased CD4+ Th17 cells compared to men with severe asthma. Previously, we showed that 17 β-estradiol and progesterone (P4) increased IL-17A production in Th17 cells by decreasing Let-7f microRNA expression and increasing IL-23 receptor (IL-23R) expression. However, it was unclear how estrogen receptor (ER) signaling regulated this pathway. We hypothesize that ER signaling promotes IL-1 7A production in Th17 cells by negatively regulating let7f expression to increase IL-23R signaling. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U6Z0ed
For individuals with peanut allergy, avoiding illness can at times be difficult due to undetermined amounts of allergens in foods. A portable consumer device for testing peanut levels in foods could aid. Described are independent validation studies to evaluate the performance of such a newly developed portable peanut sensor for foods. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BPifC0
We demonstrate that blocking the mevalonate pathway and protein prenylation in human monocytes leads to enhanced activity of an NLRP3-dependent, but not Pyrin-dependent, inflammasome, suggesting a prominent role for NLRP3 in the pathogenesis of mevalonate kinase deficiency. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U4rV2M
The report by Glesner et al1 studied the relative potency of 12 nonstandardized German cockroach extracts and 8 allergenic molecules (Bla g 1, 2, 4, 5, 6, 9, and 11 and Per a 7) by using direct human IgE antibody binding with ImmunoCAP assays and in-house competitive IgE antibody inhibition assays. Importantly, the invest igators included 3 new allergens (Bla g 6, 9, and 11) and used a robust study design involving individual sera, various extracts, and a comprehensive list of allergens. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BTOakL
An increasing number of cases of alpha-gal allergy (AGA) have been reported in the U.S. and in several parts of the world over the past decade. In the U.S., cases of AGA are most often reported in the southeastern region, overlapping with the distribution of the Lone Star tick. However, epidemiological and time trend studies on AGA are lacking. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U4rLbG
Episodic angioedema with eosinophilia, or Gleich syndrome, is a rare disorder characterized by periodic episodes of angioedema and leukocytosis with marked eosinophilia. Symptoms resolve spontaneously or are treated with corticosteroids as first-line therapy. Treatment of patients unresponsive to or dependent on corticosteroids is poorly defined. Several rheumatologic diseases, including rheumatoid arthritis (RA), can also present with elevated eosinophilia in blood or tissue. Here we present a case of steroid-dependent Gleich syndrome complicated by concurrent rheumatoid arthritis. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BU81jJ
The effects of Omalizumab on food allergy thresholds are poorly studied out of the context of Oral Immunotherapy. This real life study aims to assess the effect of Omalizumab on food tolerance in children treated for severe asthma. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BQfXmc
A 2016 AAAAI position statement recommended routine evaluation of beta-lactam allergies due to the burden of pervasive mislabeled allergies. This quality improvement study implemented strategies to expedite evaluation at Rady Children 's Hospital. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BRFuLY
Glucocorticoids (GC) remain the most commonly used therapy for eosinophil-associated disorders (EAD). Prolonged treatment is associated with significant side effects and resistance that commonly lead to drug discontinuation. Whereas rapid disappearance of blood eosinophils following a single dose of GC is characteristic, the mechanisms by which this occurs is unknown. To explore this, we developed a novel radiolabeling technique to track eosinophils following GC administration in vivo in a rhesus macaque model. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U8AKbC
Allergen-specific immunotherapy (AIT) is the only curative option of allergic diseases. However, a few proportions of allergic patients take AIT because of undesirable perspectives. In this multicenter cross-sectional study, we aimed to explore the patients ' and doctors' perspectives of AIT through personal survey. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BVdCGu
The obese asthmatic is thought to disproportionally experience greater severity, morbidity, increased exacerbations, and reduced inhaled corticosteroid responsiveness. We have previously reported that care provided by a community-based healthcare delivery system, the Breathmobile, results in improved asthma control, and reduced morbidity. We hypothesized that this system of care could provide similar outcomes for the morbidly obese compared to the normal weight asthmatic child. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U4ruWc
We reviewed authors ' gender in The Journal of Allergy and Clinical Immunology (JACI) and Annals of Allergy, Asthma and Immunology (Annals) from 1997-2007 to determine frequency and patterns of publication by gender. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BWLUcx
This study describes the current prevalence, severity, and determinants of sesame allergy among the U.S. population. It was hypothesized that current prevalence rates of sesame allergy are comparable to rates of other food allergies for which labeling is legally mandated. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U4fIuF
Disruption of epidermal tight junctions (TJs), is thought to promote immunological responses to epicutaneous antigens. The Atopic Dermatitis Research Network performed a cross-sectional study to visualize TJs and Langerhans cells (LCs) in the skin of atopic dermatitis (AD) and nonatopic (NA) controls. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BQHFiQ
The measurement of drug-induced interferon-gamma releasing cells is another option to identify the culprit drug in severe cutaneous adverse reactions (SCARs) since drug provocation is contraindicated. However, its sensitivity is rather limited since other cytokines also play a role in pathogenesis of drug hypersensitivity. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U7kkAj
Prior retrospective studies suggest differences in food allergen sensitization and comorbid atopic disease between African American and Caucasian children. As part of FORWARD, we aimed to characterize the food allergy (FA) phenotypic differences between AA and Caucasian children. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BQYkCG
Women have increased prevalence of severe asthma and increased CD4+ Th17 cells compared to men with severe asthma. Previously, we showed that 17 β-estradiol and progesterone (P4) increased IL-17A production in Th17 cells by decreasing Let-7f microRNA expression and increasing IL-23 receptor (IL-23R) expression. However, it was unclear how estrogen receptor (ER) signaling regulated this pathway. We hypothesize that ER signaling promotes IL-1 7A production in Th17 cells by negatively regulating let7f expression to increase IL-23R signaling. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U6Z0ed
The oral food challenge (OFC) is the gold-standard to diagnose food allergy (FA). OFCs are frequently performed to prove tolerance or demonstrate resolution of FA. Limited data exists regarding continued consumption of a food and how often reactions occur after OFCs. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BQYhH0
Bitter taste receptors (T2Rs) are GPCRs expressed in many tissues beyond the tongue. T2Rs in airway ciliated cells participate in innate immunity by detecting bacterial lactones and quinolones to activate antimicrobial nitric oxide (NO) production that also increases mucociliary clearance. T2R polymorphisms correlate with cellular responses in vitro and clinical chronic rhinosinusitis outcomes in vivo. Because macrophages are important players in innate immunity, we investigated if primary human macrophages also express T2Rs and what signaling pathway(s) they activate. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2U7FGOb
For individuals with peanut allergy, avoiding illness can at times be difficult due to undetermined amounts of allergens in foods. A portable consumer device for testing peanut levels in foods could aid. Described are independent validation studies to evaluate the performance of such a newly developed portable peanut sensor for foods. (Source: Journal of Allergy and Clinical Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BPifC0
(MedPage Today) -- Reduced need for surgery, systemic steroids (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IDfTMi
(MedPage Today) -- No safety concerns in phase I studies (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TgZO2V
(MedPage Today) -- Patients with late-onset asthma, low lung function most responsive (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SiUSWI
From Clinical Thyroidology® for the Public: It is unclear if there is a link between hypothyroidism during pregnancy and the risk of asthma in children. The goal of this study is to examine whether hypothyroidism during pregnancy affected the risk of developing childhood asthma. Read More…
We welcome your feedback and suggestions. Let us know what you want to see in this publication.
Feedback & SuggestionsThe post Clinical Thyroidology<sup>®</sup> for the Public – Highlighted Article appeared first on American Thyroid Association.
From Clinical Thyroidology® for the Public: It is unclear if there is a link between hypothyroidism during pregnancy and the risk of asthma in children. The goal of this study is to examine whether hypothyroidism during pregnancy affected the risk of developing childhood asthma. Read More…
We welcome your feedback and suggestions. Let us know what you want to see in this publication.
Feedback & SuggestionsThe post Clinical Thyroidology<sup>®</sup> for the Public – Highlighted Article appeared first on American Thyroid Association.
From Clinical Thyroidology® for the Public: It is unclear if there is a link between hypothyroidism during pregnancy and the risk of asthma in children. The goal of this study is to examine whether hypothyroidism during pregnancy affected the risk of developing childhood asthma. Read More…
We welcome your feedback and suggestions. Let us know what you want to see in this publication.
Feedback & SuggestionsThe post Clinical Thyroidology<sup>®</sup> for the Public – Highlighted Article appeared first on American Thyroid Association.
From Clinical Thyroidology® for the Public: It is unclear if there is a link between hypothyroidism during pregnancy and the risk of asthma in children. The goal of this study is to examine whether hypothyroidism during pregnancy affected the risk of developing childhood asthma. Read More…
We welcome your feedback and suggestions. Let us know what you want to see in this publication.
Feedback & SuggestionsThe post Clinical Thyroidology<sup>®</sup> for the Public – Highlighted Article appeared first on American Thyroid Association.
Infants exposed to a diverse environment and animals have bacteria in their gut microbiomes that protect against atopy and asthma, new research shows, offering clues to future treatments.Medscape Medical News (Source: Medscape Medical News Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
National Allergy Center's two locations in California are treating people's food allergies by gradually exposing them to things they can't eat. The unapproved method is promising but dangerous. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Sopl5P
(MedPage Today) -- Reduced need for surgery, systemic steroids (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IDfTMi
B&G Foods announced today it is voluntarily recalling 1,280 cases of a single date code of 40 oz. Victoria Marinara Sauce, with a "best by" date of 03/06/2022, after learning that the product may contain cashew allergens that are not declared on the product's ingredient statement. People who have an allergy or severe sensitivity to cashew run the risk of serious or life-threatening allergic reaction if they consume this product. There is no health risk associated with this product for individuals without an allergy to tree nuts. (Source: Food and Drug Administration)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
(MedPage Today) -- No safety concerns in phase I studies (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TgZO2V
Infants exposed to a diverse environment and animals have bacteria in their gut microbiomes that protect against atopy and asthma, new research shows, offering clues to future treatments.Medscape Medical News (Source: Medscape Medical News Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
National Allergy Center's two locations in California are treating people's food allergies by gradually exposing them to things they can't eat. The unapproved method is promising but dangerous. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Sopl5P
(MedPage Today) -- Reduced need for surgery, systemic steroids (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IDfTMi
(MedPage Today) -- No safety concerns in phase I studies (Source: MedPage Today Allergy)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TgZO2V
B&G Foods announced today it is voluntarily recalling 1,280 cases of a single date code of 40 oz. Victoria Marinara Sauce, with a "best by" date of 03/06/2022, after learning that the product may contain cashew allergens that are not declared on the product's ingredient statement. People who have an allergy or severe sensitivity to cashew run the risk of serious or life-threatening allergic reaction if they consume this product. There is no health risk associated with this product for individuals without an allergy to tree nuts. (Source: Food and Drug Administration)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Laryngo-Rhino-Otol
DOI: 10.1055/a-0850-0154
Schilddrüsenkarzinome aus Residuen des Ductus thyreoglossus sind eine Seltenheit und werden meist als Zufallsbefund postoperativ festgestellt. Es gibt keine klaren Richtlinien für das korrekte therapeutische Vorgehen nach erfolgter Resektion, insbesondere bezüglich der Notwendigkeit einer totalen Thyroidektomie und Radioiodtherapie. Vor dem Hintergrund der aktuellen Literatur wird eine Fallserie von fünf Patienten mit Schilddrüsenkarzinomen in einer medianen Halszyste präsentiert. Es erfolgte eine retrospektive Analyse aller Patienten mit einem Schilddrüsenkarzinom in einer medianen Halszyste im Zeitraum zwischen 2002 und 2017.Von 578 Patienten, die aufgrund einer medianen Halszyste operiert wurden, konnte bei fünf dieser Patienten (3 Frauen, 2 Männer), im Alter von 16–73 Jahren (Altersmittelwert 51; Median 56 Jahre) ein Schilddrüsenkarzinom gesichert werden. Klinisch stellten sich alle Patienten mit einer schmerzlosen Schwellung im Bereich des Zungenbeins vor. Die Diagnose wurde in allen Fällen postoperativ gestellt, in einem Fall wurde in der präoperativen Bildgebung bereits ein Malignom vermutet. Histologisch zeigte sich in allen Fällen ein papilläres Schilddrüsenkarzinom. Vier Patienten erhielten im Intervall eine totale Thyroidektomie und Radioiodtherapie, zwei davon zusätzlich eine Neck dissection des medialen und lateralen Kompartiments, der fünfte Patient hat sich einer weiteren Diagnostik und Therapie entzogen. Es wurden in allen vier Fällen keine Karzinome der Schilddrüse oder Lymphknotenmetastasen nachgewiesen.Aufgrund der Seltenheit von Schilddrüsenkarzinomen in medianen Halszysten existiert derzeit kein standardisiertes therapeutisches Vorgehen. Es sollte eine Risikostratifizierung vorgenommen werden, um Patienten, die von einer zusätzlichen Thyroidektomie profitieren könnten, zu identifizieren. Die Prognose ist sehr gut.
[...]
© Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
Laryngo-Rhino-Otol
DOI: 10.1055/a-0839-5206
Hintergrund Die Therapie der chronischen Sinusitis frontalis stellt sich aufgrund des anatomisch engen Abflusses in die Nasenhaupthöhle häufig als problematisch dar. Neben konservativen Methoden wurden bisher auch viele chirurgische Therapieverfahren, sowohl mit als auch ohne Einsatz von Platzhaltern, jedoch ohne längerfristigen Therapieerfolg erprobt. Ziel dieser Arbeit war die klinische Testung der allgemeinen Praktikabilität und der kurz- sowie langfristige Therapieerfolg des neuartigen bioresorbierbaren Propel mini Stents. Material und Methoden In einer prospektiven Studie an 21 Patienten mit chronischer Rhinosinusitis mit Polyposis nasi wurde die chirurgische Therapie und das Einbringen des Stents dargestellt und die Degradation von insgesamt 31 Stents sowie der Erfolg dieser Therapieform über einen Zeitraum von 6 Monaten endoskopisch kontrolliert und analysiert. Ergebnisse Hinsichtlich chirurgischer Praktikabilität erwies sich der Stent mit Einführungstool als unkompliziertes und leicht bedienbares System. Alle Patienten haben die Stents gut toleriert. Die durchschnittliche, nachweisbare Materialabsorption überdauerte 28 Tage. Das Patientenkollektiv zeigte in 94 % der Fälle nach 3 Monaten und in 87 % der Fälle nach 6 Monaten einen vollständig sondierbares Neo-Ostium des Sinus frontalis. Schlussfolgerung Die Ergebnisse der prospektiven Studie zeigen insgesamt eine gute Akzeptanz bei den Patienten ohne Komplikationen sowie eine vollständige Stentdegradation. Auch die Follow-Up-Untersuchungen ergaben zufriedenstellende Ergebnisse über 6 Monate. Insbesondere unter dem Aspekt der endoskopischen Operation erwies sich das Stent-System als sehr praktikabel.
[...]
© Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
Laryngo-Rhino-Otol
DOI: 10.1055/a-0850-0154
Schilddrüsenkarzinome aus Residuen des Ductus thyreoglossus sind eine Seltenheit und werden meist als Zufallsbefund postoperativ festgestellt. Es gibt keine klaren Richtlinien für das korrekte therapeutische Vorgehen nach erfolgter Resektion, insbesondere bezüglich der Notwendigkeit einer totalen Thyroidektomie und Radioiodtherapie. Vor dem Hintergrund der aktuellen Literatur wird eine Fallserie von fünf Patienten mit Schilddrüsenkarzinomen in einer medianen Halszyste präsentiert. Es erfolgte eine retrospektive Analyse aller Patienten mit einem Schilddrüsenkarzinom in einer medianen Halszyste im Zeitraum zwischen 2002 und 2017.Von 578 Patienten, die aufgrund einer medianen Halszyste operiert wurden, konnte bei fünf dieser Patienten (3 Frauen, 2 Männer), im Alter von 16–73 Jahren (Altersmittelwert 51; Median 56 Jahre) ein Schilddrüsenkarzinom gesichert werden. Klinisch stellten sich alle Patienten mit einer schmerzlosen Schwellung im Bereich des Zungenbeins vor. Die Diagnose wurde in allen Fällen postoperativ gestellt, in einem Fall wurde in der präoperativen Bildgebung bereits ein Malignom vermutet. Histologisch zeigte sich in allen Fällen ein papilläres Schilddrüsenkarzinom. Vier Patienten erhielten im Intervall eine totale Thyroidektomie und Radioiodtherapie, zwei davon zusätzlich eine Neck dissection des medialen und lateralen Kompartiments, der fünfte Patient hat sich einer weiteren Diagnostik und Therapie entzogen. Es wurden in allen vier Fällen keine Karzinome der Schilddrüse oder Lymphknotenmetastasen nachgewiesen.Aufgrund der Seltenheit von Schilddrüsenkarzinomen in medianen Halszysten existiert derzeit kein standardisiertes therapeutisches Vorgehen. Es sollte eine Risikostratifizierung vorgenommen werden, um Patienten, die von einer zusätzlichen Thyroidektomie profitieren könnten, zu identifizieren. Die Prognose ist sehr gut.
[...]
© Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
Laryngo-Rhino-Otol
DOI: 10.1055/a-0839-5206
Hintergrund Die Therapie der chronischen Sinusitis frontalis stellt sich aufgrund des anatomisch engen Abflusses in die Nasenhaupthöhle häufig als problematisch dar. Neben konservativen Methoden wurden bisher auch viele chirurgische Therapieverfahren, sowohl mit als auch ohne Einsatz von Platzhaltern, jedoch ohne längerfristigen Therapieerfolg erprobt. Ziel dieser Arbeit war die klinische Testung der allgemeinen Praktikabilität und der kurz- sowie langfristige Therapieerfolg des neuartigen bioresorbierbaren Propel mini Stents. Material und Methoden In einer prospektiven Studie an 21 Patienten mit chronischer Rhinosinusitis mit Polyposis nasi wurde die chirurgische Therapie und das Einbringen des Stents dargestellt und die Degradation von insgesamt 31 Stents sowie der Erfolg dieser Therapieform über einen Zeitraum von 6 Monaten endoskopisch kontrolliert und analysiert. Ergebnisse Hinsichtlich chirurgischer Praktikabilität erwies sich der Stent mit Einführungstool als unkompliziertes und leicht bedienbares System. Alle Patienten haben die Stents gut toleriert. Die durchschnittliche, nachweisbare Materialabsorption überdauerte 28 Tage. Das Patientenkollektiv zeigte in 94 % der Fälle nach 3 Monaten und in 87 % der Fälle nach 6 Monaten einen vollständig sondierbares Neo-Ostium des Sinus frontalis. Schlussfolgerung Die Ergebnisse der prospektiven Studie zeigen insgesamt eine gute Akzeptanz bei den Patienten ohne Komplikationen sowie eine vollständige Stentdegradation. Auch die Follow-Up-Untersuchungen ergaben zufriedenstellende Ergebnisse über 6 Monate. Insbesondere unter dem Aspekt der endoskopischen Operation erwies sich das Stent-System als sehr praktikabel.
[...]
© Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
Sharing radiologic image annotations among multiple institutions is important in many clinical scenarios; however, interoperability is prevented because different vendors' PACS store annotations in non-standardized formats that lack semantic interoperability. Our goal was to develop software to automate the conversion of image annotations in a commercial PACS to the Annotation and Image Markup (AIM) standardized format and demonstrate the utility of this conversion for automated matching of lesion measurements across time points for cancer lesion tracking. We created a software module in Java to parse the DICOM presentation state (DICOM-PS) objects (that contain the image annotations) for imaging studies exported from a commercial PACS (GE Centricity v3.x). Our software identifies line annotations encoded within the DICOM-PS objects and exports the annotations in the AIM format. A separate Python script processes the AIM annotation files to match line measurements (on lesions) across time points by tracking the 3D coordinates of annotated lesions. To validate the interoperability of our approach, we exported annotations from Centricity PACS into ePAD (http://epad.stanford.edu) (Rubin et al., Transl Oncol 7(1):23–35, 2014), a freely available AIM-compliant workstation, and the lesion measurement annotations were correctly linked by ePAD across sequential imaging studies. As quantitative imaging becomes more prevalent in radiology, interoperability of image annotations gains increasing importance. Our work demonstrates that image annotations in a vendor system lacking standard semantics can be automatically converted to a standardized metadata format such as AIM, enabling interoperability and potentially facilitating large-scale analysis of image annotations and the generation of high-quality labels for deep learning initiatives. This effort could be extended for use with other vendors' PACS.
Sharing radiologic image annotations among multiple institutions is important in many clinical scenarios; however, interoperability is prevented because different vendors' PACS store annotations in non-standardized formats that lack semantic interoperability. Our goal was to develop software to automate the conversion of image annotations in a commercial PACS to the Annotation and Image Markup (AIM) standardized format and demonstrate the utility of this conversion for automated matching of lesion measurements across time points for cancer lesion tracking. We created a software module in Java to parse the DICOM presentation state (DICOM-PS) objects (that contain the image annotations) for imaging studies exported from a commercial PACS (GE Centricity v3.x). Our software identifies line annotations encoded within the DICOM-PS objects and exports the annotations in the AIM format. A separate Python script processes the AIM annotation files to match line measurements (on lesions) across time points by tracking the 3D coordinates of annotated lesions. To validate the interoperability of our approach, we exported annotations from Centricity PACS into ePAD (http://epad.stanford.edu) (Rubin et al., Transl Oncol 7(1):23–35, 2014), a freely available AIM-compliant workstation, and the lesion measurement annotations were correctly linked by ePAD across sequential imaging studies. As quantitative imaging becomes more prevalent in radiology, interoperability of image annotations gains increasing importance. Our work demonstrates that image annotations in a vendor system lacking standard semantics can be automatically converted to a standardized metadata format such as AIM, enabling interoperability and potentially facilitating large-scale analysis of image annotations and the generation of high-quality labels for deep learning initiatives. This effort could be extended for use with other vendors' PACS.
There is a paucity of plasma‐based biomarkers that predict outcome in patients with head and neck squamous cell carcinoma (HNSCC) treated with chemoradiation therapy (CRT). Here, we evaluate the prognostic potential of plasma Melanoma‐Antigen Recognized by T‐cells 1 (MLANA) in this setting.
MLANA expression in HNSCC lines were evaluated by reverse transcription polymerase chain reaction, whereas plasma levels were quantified using ELISA in 48 patients with locally advanced HNSCC undergoing a phase 2 trial with CRT.
MLANA is expressed at variable levels in a panel of HNSCC lines. In plasma, levels were elevated in patients with tumor relapse compared to those without (P < .004); 73.9% of the patients expressing high plasma MLANA levels progressed with recurrent disease (P = .020). Multivariate analysis showed that plasma MLANA levels and tumor resectability were independent prognostic factors for progression free survival.
Plasma MLANA expression appears to be an effective noninvasive biomarker for outcomes in patients treated with CRT, and could potentially guide therapeutic decisions in this context.
There is a paucity of plasma‐based biomarkers that predict outcome in patients with head and neck squamous cell carcinoma (HNSCC) treated with chemoradiation therapy (CRT). Here, we evaluate the prognostic potential of plasma Melanoma‐Antigen Recognized by T‐cells 1 (MLANA) in this setting.
MLANA expression in HNSCC lines were evaluated by reverse transcription polymerase chain reaction, whereas plasma levels were quantified using ELISA in 48 patients with locally advanced HNSCC undergoing a phase 2 trial with CRT.
MLANA is expressed at variable levels in a panel of HNSCC lines. In plasma, levels were elevated in patients with tumor relapse compared to those without (P < .004); 73.9% of the patients expressing high plasma MLANA levels progressed with recurrent disease (P = .020). Multivariate analysis showed that plasma MLANA levels and tumor resectability were independent prognostic factors for progression free survival.
Plasma MLANA expression appears to be an effective noninvasive biomarker for outcomes in patients treated with CRT, and could potentially guide therapeutic decisions in this context.
The influence of different timing for soft tissue augmentation during implant therapy is still debated. Therefore, the present study aimed to evaluate clinically whether immediate versus delayed soft tissue augmentation procedures had an impact on the stability of peri-implant mucosal thickness.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOIwp
Pain, anxiety, and nervousness related to dental procedures can cause acute changes in the autonomic nervous system. Music is widely accepted as a relaxation method during dental treatment; however, its effects during dental treatment are unclear. We explored the effects of music listening during extraction of the impacted mandibular third molar on the autonomic nervous system and the psychological state, and hypothesized that music listening would suppress sympathetic nervous activity and reduce anxiety.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IEfUQb
The purpose of this study was to answer the following question: among female patients who have skeletal Class III malocclusion, does poor sleep quality increase the prevalence of degenerative joint changes in temporomandibular joints (DJC-TMJ)?
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOCF3
This study focused on quality of life for patients in northeast China who underwent oral cancer resection directly before flap reconstruction. Additionally, this study compared differences between the radial forearm free flap (RFFF), ulnar forearm free flap (UFFF), and anterolateral thigh flap (ALTF) for defect reconstruction.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICvXOD
Since no study has evaluated the post-operative pain caused by dental implants shape up to now, the aim of this study was to compare the amount of postoperative pain between tapered and cylindrical implants inserted in the posterior region of the maxilla.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOyoN
Ameloblastomas typically occur in adults but is considered a rarity in the paediatric patient population. We report on the treatment outcome of a paediatric patient who presented with a unicystic ameloblastoma in the mandible
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICnTNO
A growing concern in the community of oral and maxillofacial surgeons (OMSs) is the progressive hearing loss that has become more evident in older surgeons. Very few studies have focused on the effects on a surgeon's hearing based on their environment. The purpose of this study was to investigate whether or not the noise produced by suction, compared to federal guidelines, could have a damaging effect on the hearing of OMSs.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOrcR
Idiopathic condylar resorption (ICR) is an aggressive form of osteoarthritis that is frequently observed in adolescent females. We hypothesize that an estrogen-mediated pathway may contribute to ICR development.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IL3s1k
This study focused on quality of life for patients in northeast China who underwent oral cancer resection directly before flap reconstruction. Additionally, this study compared differences between the radial forearm free flap (RFFF), ulnar forearm free flap (UFFF), and anterolateral thigh flap (ALTF) for defect reconstruction.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICvXOD
The influence of different timing for soft tissue augmentation during implant therapy is still debated. Therefore, the present study aimed to evaluate clinically whether immediate versus delayed soft tissue augmentation procedures had an impact on the stability of peri-implant mucosal thickness.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOIwp
Pain, anxiety, and nervousness related to dental procedures can cause acute changes in the autonomic nervous system. Music is widely accepted as a relaxation method during dental treatment; however, its effects during dental treatment are unclear. We explored the effects of music listening during extraction of the impacted mandibular third molar on the autonomic nervous system and the psychological state, and hypothesized that music listening would suppress sympathetic nervous activity and reduce anxiety.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IEfUQb
The purpose of this study was to answer the following question: among female patients who have skeletal Class III malocclusion, does poor sleep quality increase the prevalence of degenerative joint changes in temporomandibular joints (DJC-TMJ)?
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOCF3
Since no study has evaluated the post-operative pain caused by dental implants shape up to now, the aim of this study was to compare the amount of postoperative pain between tapered and cylindrical implants inserted in the posterior region of the maxilla.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOyoN
Ameloblastomas typically occur in adults but is considered a rarity in the paediatric patient population. We report on the treatment outcome of a paediatric patient who presented with a unicystic ameloblastoma in the mandible
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICnTNO
A growing concern in the community of oral and maxillofacial surgeons (OMSs) is the progressive hearing loss that has become more evident in older surgeons. Very few studies have focused on the effects on a surgeon's hearing based on their environment. The purpose of this study was to investigate whether or not the noise produced by suction, compared to federal guidelines, could have a damaging effect on the hearing of OMSs.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOrcR
Idiopathic condylar resorption (ICR) is an aggressive form of osteoarthritis that is frequently observed in adolescent females. We hypothesize that an estrogen-mediated pathway may contribute to ICR development.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IL3s1k
The influence of different timing for soft tissue augmentation during implant therapy is still debated. Therefore, the present study aimed to evaluate clinically whether immediate versus delayed soft tissue augmentation procedures had an impact on the stability of peri-implant mucosal thickness.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOIwp
Pain, anxiety, and nervousness related to dental procedures can cause acute changes in the autonomic nervous system. Music is widely accepted as a relaxation method during dental treatment; however, its effects during dental treatment are unclear. We explored the effects of music listening during extraction of the impacted mandibular third molar on the autonomic nervous system and the psychological state, and hypothesized that music listening would suppress sympathetic nervous activity and reduce anxiety.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IEfUQb
The purpose of this study was to answer the following question: among female patients who have skeletal Class III malocclusion, does poor sleep quality increase the prevalence of degenerative joint changes in temporomandibular joints (DJC-TMJ)?
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOCF3
This study focused on quality of life for patients in northeast China who underwent oral cancer resection directly before flap reconstruction. Additionally, this study compared differences between the radial forearm free flap (RFFF), ulnar forearm free flap (UFFF), and anterolateral thigh flap (ALTF) for defect reconstruction.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICvXOD
Since no study has evaluated the post-operative pain caused by dental implants shape up to now, the aim of this study was to compare the amount of postoperative pain between tapered and cylindrical implants inserted in the posterior region of the maxilla.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOyoN
Ameloblastomas typically occur in adults but is considered a rarity in the paediatric patient population. We report on the treatment outcome of a paediatric patient who presented with a unicystic ameloblastoma in the mandible
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICnTNO
A growing concern in the community of oral and maxillofacial surgeons (OMSs) is the progressive hearing loss that has become more evident in older surgeons. Very few studies have focused on the effects on a surgeon's hearing based on their environment. The purpose of this study was to investigate whether or not the noise produced by suction, compared to federal guidelines, could have a damaging effect on the hearing of OMSs.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOrcR
Idiopathic condylar resorption (ICR) is an aggressive form of osteoarthritis that is frequently observed in adolescent females. We hypothesize that an estrogen-mediated pathway may contribute to ICR development.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IL3s1k
The influence of different timing for soft tissue augmentation during implant therapy is still debated. Therefore, the present study aimed to evaluate clinically whether immediate versus delayed soft tissue augmentation procedures had an impact on the stability of peri-implant mucosal thickness.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOIwp
Pain, anxiety, and nervousness related to dental procedures can cause acute changes in the autonomic nervous system. Music is widely accepted as a relaxation method during dental treatment; however, its effects during dental treatment are unclear. We explored the effects of music listening during extraction of the impacted mandibular third molar on the autonomic nervous system and the psychological state, and hypothesized that music listening would suppress sympathetic nervous activity and reduce anxiety.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IEfUQb
The purpose of this study was to answer the following question: among female patients who have skeletal Class III malocclusion, does poor sleep quality increase the prevalence of degenerative joint changes in temporomandibular joints (DJC-TMJ)?
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOCF3
This study focused on quality of life for patients in northeast China who underwent oral cancer resection directly before flap reconstruction. Additionally, this study compared differences between the radial forearm free flap (RFFF), ulnar forearm free flap (UFFF), and anterolateral thigh flap (ALTF) for defect reconstruction.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICvXOD
Since no study has evaluated the post-operative pain caused by dental implants shape up to now, the aim of this study was to compare the amount of postoperative pain between tapered and cylindrical implants inserted in the posterior region of the maxilla.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOyoN
Ameloblastomas typically occur in adults but is considered a rarity in the paediatric patient population. We report on the treatment outcome of a paediatric patient who presented with a unicystic ameloblastoma in the mandible
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ICnTNO
A growing concern in the community of oral and maxillofacial surgeons (OMSs) is the progressive hearing loss that has become more evident in older surgeons. Very few studies have focused on the effects on a surgeon's hearing based on their environment. The purpose of this study was to investigate whether or not the noise produced by suction, compared to federal guidelines, could have a damaging effect on the hearing of OMSs.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TbOrcR
Idiopathic condylar resorption (ICR) is an aggressive form of osteoarthritis that is frequently observed in adolescent females. We hypothesize that an estrogen-mediated pathway may contribute to ICR development.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IL3s1k
Breast conservation therapy (BCT) can cause breast distortion and asymmetry. Repair of this asymmetry by means of breast reduction or mastopexy procedures can be challenging and harbor considerably high rates of complications.
In this retrospective study, we describe our experience in repairing post-BCT breast asymmetry by performing breast reduction or mastopexy. The surgical protocol we followed consisted of stringent patient selection, thorough surgical planning, basic surgical refinements, and patient education for enhancing the likelihood of achieving a good outcome with minimal surgical complications.
Our search of the departmental database identified 25 patients with breast asymmetry who had undergone breast reduction or mastopexy between 2009 and 2017. Corrective surgery was performed 4 years on average after the completion of radiotherapy, and those patients included eleven who had undergone breast reduction and fourteen who had undergone mastopexy on the radiated side. Two patients (8%) had major complications that required further surgery (major fat necrosis, wound infection, and breast deformation), and five patients (20%) had minor complications (infection, minor fat necrosis, wound dehiscence, and nipple congestion). All complications developed on the radiated breast. There was no correlation between the occurrence of complications and patients' demographics, tumor type, tumor location, and breast tissue resection (p > 0.05).
Only two of our 25 patients had major complications following breast reduction and mastopexy for the repair of asymmetry post-BCT. Following our four-step protocol was instrumental in leading to the successful performance of these procedures.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Psychological factors play a major role in the tendency toward cosmetic surgery. Variety seeking, making changes in one's face and reducing apparent dissatisfaction, improving body image and increasing sexual self-esteem can be considered as some psychological aspects of cosmetic surgery. The present study was conducted with the aim of evaluating the changes in the indices of body image concern, sexual self-esteem and sexual body image in patients undergoing rhinoplasty.
This study was a single-group pretest–posttest quasi-experimental design. The research data were collected from March 2015 to January 2016. For this purpose, of the patients seeking nose surgery who referred to beauty centers in Mashhad, 40 subjects were selected through purposive method sampling and completed a Body Image Concern Inventory, Sexual Self-Esteem Index for Women and Body Exposure during Sexual Activities Questionnaire before and after rhinoplasty. These data were collected after obtaining informed consent, conducting a structured clinical interview and completing the demographic checklist.
Data analysis demonstrated that there is a significant improvement in the index of female body image concern after rhinoplasty (p < 0.05). In the indices of sexual self-esteem and sexual body image, the analyses showed no significant difference between the pretest and posttest scores (p > 0.05).
Cosmetic surgery leads to the reduced body image concern of women but has no effect on sexual self-esteem and sexual body image. It seems that the psychological function of patients does not change significantly by rhinoplasty dimensions.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Breast conservation therapy (BCT) can cause breast distortion and asymmetry. Repair of this asymmetry by means of breast reduction or mastopexy procedures can be challenging and harbor considerably high rates of complications.
In this retrospective study, we describe our experience in repairing post-BCT breast asymmetry by performing breast reduction or mastopexy. The surgical protocol we followed consisted of stringent patient selection, thorough surgical planning, basic surgical refinements, and patient education for enhancing the likelihood of achieving a good outcome with minimal surgical complications.
Our search of the departmental database identified 25 patients with breast asymmetry who had undergone breast reduction or mastopexy between 2009 and 2017. Corrective surgery was performed 4 years on average after the completion of radiotherapy, and those patients included eleven who had undergone breast reduction and fourteen who had undergone mastopexy on the radiated side. Two patients (8%) had major complications that required further surgery (major fat necrosis, wound infection, and breast deformation), and five patients (20%) had minor complications (infection, minor fat necrosis, wound dehiscence, and nipple congestion). All complications developed on the radiated breast. There was no correlation between the occurrence of complications and patients' demographics, tumor type, tumor location, and breast tissue resection (p > 0.05).
Only two of our 25 patients had major complications following breast reduction and mastopexy for the repair of asymmetry post-BCT. Following our four-step protocol was instrumental in leading to the successful performance of these procedures.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Psychological factors play a major role in the tendency toward cosmetic surgery. Variety seeking, making changes in one's face and reducing apparent dissatisfaction, improving body image and increasing sexual self-esteem can be considered as some psychological aspects of cosmetic surgery. The present study was conducted with the aim of evaluating the changes in the indices of body image concern, sexual self-esteem and sexual body image in patients undergoing rhinoplasty.
This study was a single-group pretest–posttest quasi-experimental design. The research data were collected from March 2015 to January 2016. For this purpose, of the patients seeking nose surgery who referred to beauty centers in Mashhad, 40 subjects were selected through purposive method sampling and completed a Body Image Concern Inventory, Sexual Self-Esteem Index for Women and Body Exposure during Sexual Activities Questionnaire before and after rhinoplasty. These data were collected after obtaining informed consent, conducting a structured clinical interview and completing the demographic checklist.
Data analysis demonstrated that there is a significant improvement in the index of female body image concern after rhinoplasty (p < 0.05). In the indices of sexual self-esteem and sexual body image, the analyses showed no significant difference between the pretest and posttest scores (p > 0.05).
Cosmetic surgery leads to the reduced body image concern of women but has no effect on sexual self-esteem and sexual body image. It seems that the psychological function of patients does not change significantly by rhinoplasty dimensions.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Breast conservation therapy (BCT) can cause breast distortion and asymmetry. Repair of this asymmetry by means of breast reduction or mastopexy procedures can be challenging and harbor considerably high rates of complications.
In this retrospective study, we describe our experience in repairing post-BCT breast asymmetry by performing breast reduction or mastopexy. The surgical protocol we followed consisted of stringent patient selection, thorough surgical planning, basic surgical refinements, and patient education for enhancing the likelihood of achieving a good outcome with minimal surgical complications.
Our search of the departmental database identified 25 patients with breast asymmetry who had undergone breast reduction or mastopexy between 2009 and 2017. Corrective surgery was performed 4 years on average after the completion of radiotherapy, and those patients included eleven who had undergone breast reduction and fourteen who had undergone mastopexy on the radiated side. Two patients (8%) had major complications that required further surgery (major fat necrosis, wound infection, and breast deformation), and five patients (20%) had minor complications (infection, minor fat necrosis, wound dehiscence, and nipple congestion). All complications developed on the radiated breast. There was no correlation between the occurrence of complications and patients' demographics, tumor type, tumor location, and breast tissue resection (p > 0.05).
Only two of our 25 patients had major complications following breast reduction and mastopexy for the repair of asymmetry post-BCT. Following our four-step protocol was instrumental in leading to the successful performance of these procedures.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Psychological factors play a major role in the tendency toward cosmetic surgery. Variety seeking, making changes in one's face and reducing apparent dissatisfaction, improving body image and increasing sexual self-esteem can be considered as some psychological aspects of cosmetic surgery. The present study was conducted with the aim of evaluating the changes in the indices of body image concern, sexual self-esteem and sexual body image in patients undergoing rhinoplasty.
This study was a single-group pretest–posttest quasi-experimental design. The research data were collected from March 2015 to January 2016. For this purpose, of the patients seeking nose surgery who referred to beauty centers in Mashhad, 40 subjects were selected through purposive method sampling and completed a Body Image Concern Inventory, Sexual Self-Esteem Index for Women and Body Exposure during Sexual Activities Questionnaire before and after rhinoplasty. These data were collected after obtaining informed consent, conducting a structured clinical interview and completing the demographic checklist.
Data analysis demonstrated that there is a significant improvement in the index of female body image concern after rhinoplasty (p < 0.05). In the indices of sexual self-esteem and sexual body image, the analyses showed no significant difference between the pretest and posttest scores (p > 0.05).
Cosmetic surgery leads to the reduced body image concern of women but has no effect on sexual self-esteem and sexual body image. It seems that the psychological function of patients does not change significantly by rhinoplasty dimensions.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
A catalytic DNA that slashes rhinovirus genomic RNA effectively wipes out 98% of strains, German researchers show in preliminary study that is garnering attention.Medscape Medical News (Source: Medscape Medical News Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Researchers in San Francisco surveyed 2,586 breastfeeding mothers and tracked the health of their babies. Those who introduced 'trigger' foods from seven months had a lower risk of allergies. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ThgKqf
-- Dry, cold air can trigger asthma attacks, the Asthma and Allergy Foundation of America says. Breathing in the winter air can cause airways to restrict, making it difficult to breathe. The foundation offers suggestions to reduce asthma attacks... (Source: Drugs.com - Daily MedNews)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IALw9e
(McMaster University) Two McMaster University physicians have five facts about penicillin allergy published today in the Canadian Medical Association Journal (CMAJ). Derek Chu is a fellow in clinical immunology and allergy and David McCullagh is a fellow in infectious disease in the Department of Medicine. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tfg7gH
(National Research University Higher School of Economics) Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS), and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases. The researchers published their results in Nature Immunology.https://ift.tt/2Ixkkbp (Source: EurekAlert! - Medicine and Health)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
(Aarhus University) A previously unknown messenger which alarms nearby cells when the immune system recognises a bacterial or viral infection has been uncovered. Immunologists from Aarhus University, Denmark, are behind the discovery, which will help fighting infections and autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tk5JUU
A catalytic DNA that slashes rhinovirus genomic RNA effectively wipes out 98% of strains, German researchers show in preliminary study that is garnering attention.Medscape Medical News (Source: Medscape Medical News Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Researchers in San Francisco surveyed 2,586 breastfeeding mothers and tracked the health of their babies. Those who introduced 'trigger' foods from seven months had a lower risk of allergies. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ThgKqf
-- Dry, cold air can trigger asthma attacks, the Asthma and Allergy Foundation of America says. Breathing in the winter air can cause airways to restrict, making it difficult to breathe. The foundation offers suggestions to reduce asthma attacks... (Source: Drugs.com - Daily MedNews)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IALw9e
(McMaster University) Two McMaster University physicians have five facts about penicillin allergy published today in the Canadian Medical Association Journal (CMAJ). Derek Chu is a fellow in clinical immunology and allergy and David McCullagh is a fellow in infectious disease in the Department of Medicine. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tfg7gH
(National Research University Higher School of Economics) Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS), and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases. The researchers published their results in Nature Immunology.https://ift.tt/2Ixkkbp (Source: EurekAlert! - Medicine and Health)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
(Aarhus University) A previously unknown messenger which alarms nearby cells when the immune system recognises a bacterial or viral infection has been uncovered. Immunologists from Aarhus University, Denmark, are behind the discovery, which will help fighting infections and autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tk5JUU
Breast conservation therapy (BCT) can cause breast distortion and asymmetry. Repair of this asymmetry by means of breast reduction or mastopexy procedures can be challenging and harbor considerably high rates of complications.
In this retrospective study, we describe our experience in repairing post-BCT breast asymmetry by performing breast reduction or mastopexy. The surgical protocol we followed consisted of stringent patient selection, thorough surgical planning, basic surgical refinements, and patient education for enhancing the likelihood of achieving a good outcome with minimal surgical complications.
Our search of the departmental database identified 25 patients with breast asymmetry who had undergone breast reduction or mastopexy between 2009 and 2017. Corrective surgery was performed 4 years on average after the completion of radiotherapy, and those patients included eleven who had undergone breast reduction and fourteen who had undergone mastopexy on the radiated side. Two patients (8%) had major complications that required further surgery (major fat necrosis, wound infection, and breast deformation), and five patients (20%) had minor complications (infection, minor fat necrosis, wound dehiscence, and nipple congestion). All complications developed on the radiated breast. There was no correlation between the occurrence of complications and patients' demographics, tumor type, tumor location, and breast tissue resection (p > 0.05).
Only two of our 25 patients had major complications following breast reduction and mastopexy for the repair of asymmetry post-BCT. Following our four-step protocol was instrumental in leading to the successful performance of these procedures.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Psychological factors play a major role in the tendency toward cosmetic surgery. Variety seeking, making changes in one's face and reducing apparent dissatisfaction, improving body image and increasing sexual self-esteem can be considered as some psychological aspects of cosmetic surgery. The present study was conducted with the aim of evaluating the changes in the indices of body image concern, sexual self-esteem and sexual body image in patients undergoing rhinoplasty.
This study was a single-group pretest–posttest quasi-experimental design. The research data were collected from March 2015 to January 2016. For this purpose, of the patients seeking nose surgery who referred to beauty centers in Mashhad, 40 subjects were selected through purposive method sampling and completed a Body Image Concern Inventory, Sexual Self-Esteem Index for Women and Body Exposure during Sexual Activities Questionnaire before and after rhinoplasty. These data were collected after obtaining informed consent, conducting a structured clinical interview and completing the demographic checklist.
Data analysis demonstrated that there is a significant improvement in the index of female body image concern after rhinoplasty (p < 0.05). In the indices of sexual self-esteem and sexual body image, the analyses showed no significant difference between the pretest and posttest scores (p > 0.05).
Cosmetic surgery leads to the reduced body image concern of women but has no effect on sexual self-esteem and sexual body image. It seems that the psychological function of patients does not change significantly by rhinoplasty dimensions.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
A catalytic DNA that slashes rhinovirus genomic RNA effectively wipes out 98% of strains, German researchers show in preliminary study that is garnering attention.Medscape Medical News (Source: Medscape Medical News Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Researchers in San Francisco surveyed 2,586 breastfeeding mothers and tracked the health of their babies. Those who introduced 'trigger' foods from seven months had a lower risk of allergies. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ThgKqf
-- Dry, cold air can trigger asthma attacks, the Asthma and Allergy Foundation of America says. Breathing in the winter air can cause airways to restrict, making it difficult to breathe. The foundation offers suggestions to reduce asthma attacks... (Source: Drugs.com - Daily MedNews)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IALw9e
(McMaster University) Two McMaster University physicians have five facts about penicillin allergy published today in the Canadian Medical Association Journal (CMAJ). Derek Chu is a fellow in clinical immunology and allergy and David McCullagh is a fellow in infectious disease in the Department of Medicine. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tfg7gH
(National Research University Higher School of Economics) Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS), and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases. The researchers published their results in Nature Immunology.https://ift.tt/2Ixkkbp (Source: EurekAlert! - Medicine and Health)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
(Aarhus University) A previously unknown messenger which alarms nearby cells when the immune system recognises a bacterial or viral infection has been uncovered. Immunologists from Aarhus University, Denmark, are behind the discovery, which will help fighting infections and autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tk5JUU
A catalytic DNA that slashes rhinovirus genomic RNA effectively wipes out 98% of strains, German researchers show in preliminary study that is garnering attention.Medscape Medical News (Source: Medscape Medical News Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Researchers in San Francisco surveyed 2,586 breastfeeding mothers and tracked the health of their babies. Those who introduced 'trigger' foods from seven months had a lower risk of allergies. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ThgKqf
-- Dry, cold air can trigger asthma attacks, the Asthma and Allergy Foundation of America says. Breathing in the winter air can cause airways to restrict, making it difficult to breathe. The foundation offers suggestions to reduce asthma attacks... (Source: Drugs.com - Daily MedNews)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2IALw9e
(McMaster University) Two McMaster University physicians have five facts about penicillin allergy published today in the Canadian Medical Association Journal (CMAJ). Derek Chu is a fellow in clinical immunology and allergy and David McCullagh is a fellow in infectious disease in the Department of Medicine. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tfg7gH
(National Research University Higher School of Economics) Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS), and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases. The researchers published their results in Nature Immunology.https://ift.tt/2Ixkkbp (Source: EurekAlert! - Medicine and Health)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
(Aarhus University) A previously unknown messenger which alarms nearby cells when the immune system recognises a bacterial or viral infection has been uncovered. Immunologists from Aarhus University, Denmark, are behind the discovery, which will help fighting infections and autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tk5JUU
Fragrance contact allergy is common, but few studies on quality of life (QoL) in affected patients exist. Recently, the disease‐specific Fragrance Quality of Life Index (FQLI) was developed.
To characterize QoL in European dermatitis patients with fragrance contact allergy at time of diagnosis.
Cross‐sectional study, inviting 2011 Danish, British, Spanish and German adult consecutive dermatitis patients to complete a questionnaire on self‐reported disease severity, the Dermatology Quality of Life Index (DLQI), and the FQLI immediately prior to being patch tested.
1758 patients responded and 259 (14.7%, country range 11.7‐18.5%) were fragrance positive. Among these, total (SD) DLQI score was 6.2 (5.6) and total (SD) FQLI score was 60 (25), with both estimates being comparable to fragrance negative patients. Adjusting total FQLI score for age, sex and self‐rated disease severity revealed a higher (i.e. worse) score in fragrance positive patients (3.6‐point increase, 95% CI: 0.30 to 6.8 points, P=0.03). Specifically, contact allergy to oxidized linalool was associated with greater impairment in QoL.
QoL in patients with fragrance contact allergy is impaired at a level comparable to other patch tested dermatitis patients, at time of diagnosis across several European countries.
This article is protected by copyright. All rights reserved.
Fragrance contact allergy is common, but few studies on quality of life (QoL) in affected patients exist. Recently, the disease‐specific Fragrance Quality of Life Index (FQLI) was developed.
To characterize QoL in European dermatitis patients with fragrance contact allergy at time of diagnosis.
Cross‐sectional study, inviting 2011 Danish, British, Spanish and German adult consecutive dermatitis patients to complete a questionnaire on self‐reported disease severity, the Dermatology Quality of Life Index (DLQI), and the FQLI immediately prior to being patch tested.
1758 patients responded and 259 (14.7%, country range 11.7‐18.5%) were fragrance positive. Among these, total (SD) DLQI score was 6.2 (5.6) and total (SD) FQLI score was 60 (25), with both estimates being comparable to fragrance negative patients. Adjusting total FQLI score for age, sex and self‐rated disease severity revealed a higher (i.e. worse) score in fragrance positive patients (3.6‐point increase, 95% CI: 0.30 to 6.8 points, P=0.03). Specifically, contact allergy to oxidized linalool was associated with greater impairment in QoL.
QoL in patients with fragrance contact allergy is impaired at a level comparable to other patch tested dermatitis patients, at time of diagnosis across several European countries.
This article is protected by copyright. All rights reserved.
