Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study

Conditions:   Sleep Apnea;   Allergic Rhinitis;   Allergic Asthma;   Pollution; Exposure;   Pollution Related Respiratory Disorder Intervention:   Other: Pollution exposure Sponsors:   University Hospital, Grenoble;   Assistance Publique - Hôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Bs5goP

A randomized controlled trial testing a hyaluronic acid spacer injection for skin toxicity reduction of brachytherapy accelerated partial breast irradiation (APBI): a study protocol

In this study, the effect of a subcutaneous spacer injection on the skin dose, late skin toxicity, and cosmetic outcome is tested in patients treated with PBSI in the setting of breast-conserving therapy. Our results will be relevant for most forms of breast brachytherapy as well as robotic radiosurgery, as skin spacers could protect the skin with these other techniques.Trial registrationNetherlands Trial Register,NTR6549. Registered on 27 June 2017. (Source: Trials)

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Determine Immunoglobulin G4 (IgG4) Standards for Cow's Milk and Egg in Different Populations of Allergic and Non-allergic Children

Condition:   Food Allergy in Children Intervention:   Biological: Blood collection Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QAf3DI

Development of Metabolic Syndrome in Children and Adolescents With Leukemia and Lymphomas

Condition:   Metabolic Syndrome Intervention:   Sponsor:   Federal Research Institute of Pediatric Hematology, Oncology and Immunology Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BB0y8z

Cetirizine Chewable Bioequivalence and Food Effect Study

Condition:   Allergy Interventions:   Drug: Cetirizine 10mg;   Drug: Cetirizine 10 mg Sponsor:   Johnson& Johnson Consumer Inc., McNeil Consumer Healthcare Division Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QHA53y

DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

Conditions:   Adherence, Medication;   Risk Behavior;   Pre-Exposure Prophylaxis;   HIV Prevention Interventions:   Drug: Emtricitabine / Tenofovir Disoproxil Oral Tablet;   Other: DOT Diary mobile app Sponsors:   Public Health Foundation Enterprises, Inc.;   National Institute of Mental Health (NIMH);   San Francisco Department of Public Health;   Emory University;   AiCure;   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BuxKOD

Effect of the Nasal Gel " Nascum ®-Plus " on Allergic Symptoms

Condition:   Rhinitis, Allergic, Seasonal Interventions:   Drug: Nascum Plus;   Other: ACC Sponsors:   Fraunhofer-Institute of Toxicology and Experimental Medicine;   M et P Pharma AG Enrolling by invitation (Source: ClinicalTrials.gov)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QBh0ji

Pilot Study of Short Term Aspirin on the Biologic and Immunologic Changes of the Fallopian Tube

Conditions:   Fallopian Tube Cancer;   Fallopian Tube Infection Intervention:   Drug: Aspirin 81 mg Sponsor:   University of Oklahoma Not yet recruiting (Source: ClinicalTrials.gov)

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Innovation Pharmaceuticals Completes End-of-Phase 2 Meeting with FDA; Brilacidin Oral Rinse to Advance Into Phase 3 Clinical Trials for Prevention of Severe Oral Mucositis - Nasdaq

Innovation Pharmaceuticals Completes End-of-Phase 2 Meeting with FDA; Brilacidin Oral Rinse to Advance Into Phase 3 Clinical Trials for Prevention of Severe Oral Mucositis  Nasdaq

BEVERLY, Mass., Dec. 17, 2018-- Innovation Pharmaceuticals, a clinical stage pharmaceutical company, announced today that the Company and the U.S..

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2EzMn7q

Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study

Conditions:   Sleep Apnea;   Allergic Rhinitis;   Allergic Asthma;   Pollution; Exposure;   Pollution Related Respiratory Disorder Intervention:   Other: Pollution exposure Sponsors:   University Hospital, Grenoble;   Assistance Publique - Hôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Bs5goP

A randomized controlled trial testing a hyaluronic acid spacer injection for skin toxicity reduction of brachytherapy accelerated partial breast irradiation (APBI): a study protocol

In this study, the effect of a subcutaneous spacer injection on the skin dose, late skin toxicity, and cosmetic outcome is tested in patients treated with PBSI in the setting of breast-conserving therapy. Our results will be relevant for most forms of breast brachytherapy as well as robotic radiosurgery, as skin spacers could protect the skin with these other techniques.Trial registrationNetherlands Trial Register,NTR6549. Registered on 27 June 2017. (Source: Trials)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Buvo2C

Determine Immunoglobulin G4 (IgG4) Standards for Cow's Milk and Egg in Different Populations of Allergic and Non-allergic Children

Condition:   Food Allergy in Children Intervention:   Biological: Blood collection Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QAf3DI

Development of Metabolic Syndrome in Children and Adolescents With Leukemia and Lymphomas

Condition:   Metabolic Syndrome Intervention:   Sponsor:   Federal Research Institute of Pediatric Hematology, Oncology and Immunology Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BB0y8z

Cetirizine Chewable Bioequivalence and Food Effect Study

Condition:   Allergy Interventions:   Drug: Cetirizine 10mg;   Drug: Cetirizine 10 mg Sponsor:   Johnson& Johnson Consumer Inc., McNeil Consumer Healthcare Division Recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QHA53y

DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

Conditions:   Adherence, Medication;   Risk Behavior;   Pre-Exposure Prophylaxis;   HIV Prevention Interventions:   Drug: Emtricitabine / Tenofovir Disoproxil Oral Tablet;   Other: DOT Diary mobile app Sponsors:   Public Health Foundation Enterprises, Inc.;   National Institute of Mental Health (NIMH);   San Francisco Department of Public Health;   Emory University;   AiCure;   National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BuxKOD

Effect of the Nasal Gel " Nascum ®-Plus " on Allergic Symptoms

Condition:   Rhinitis, Allergic, Seasonal Interventions:   Drug: Nascum Plus;   Other: ACC Sponsors:   Fraunhofer-Institute of Toxicology and Experimental Medicine;   M et P Pharma AG Enrolling by invitation (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QBh0ji

Pilot Study of Short Term Aspirin on the Biologic and Immunologic Changes of the Fallopian Tube

Conditions:   Fallopian Tube Cancer;   Fallopian Tube Infection Intervention:   Drug: Aspirin 81 mg Sponsor:   University of Oklahoma Not yet recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BpwTPs

Non-interventional Research Clinical Research Program for Establishment of Milk Protein Allergy Oral Immune Tolerance

Condition:   Milk Protein Allergy Intervention:   Sponsor:   Peking University Third Hospital Active, not recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QGaxDF

Rakuten Aspyrian Enrolling Phase 3 Trial of ASP-1929 for Head and Neck Cancer - PRNewswire

Rakuten Aspyrian Enrolling Phase 3 Trial of ASP-1929 for Head and Neck Cancer  PRNewswire

SAN DIEGO, Dec. 17, 2018 /PRNewswire/ -- Rakuten Aspyrian, a biotechnology company developing precision-targeted cancer therapies based on its ...

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GMFTO: Pet of the Week! - Fetchyournews.com

GMFTO: Pet of the Week!  Fetchyournews.com

Join us every Friday from Circuit World for Pet of the Week! The Humane Society of Blue Ridge has a lot of wonderful pets available for adoption.

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GMFTO: Pet of the Week! - Fetchyournews.com

GMFTO: Pet of the Week!  Fetchyournews.com

Join us every Friday from Circuit World for Pet of the Week! The Humane Society of Blue Ridge has a lot of wonderful pets available for adoption.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A2Dlfw

The importance of recognizing an association between obstructive sleep apnea and post-traumatic stress disorder (Arthur Friedlander, et al), November 2018, V76, #11

To the Editor: - The recent article in Perspectives section of the journal on recognizing an association between obstructive sleep apnea and post-traumatic stress disorder by Friedlander et al (1) was a new and interesting view on the link between two, not traditionally associated, conditions. Authors indicated the still unknown nature of this association among a selected group of patients, especially military veterans. According to presented literature, possible connections between OSA and PTSD can be attributed to either typical for OSA fragmented sleep pattern with arousals coinciding with decreased airway muscle tone that is also common for disturbing dreams and unstable upper airways of PTSD, dysfunctional REM sleep mechanism and nightmare episodes demonstrated in both disorders, and other causes.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QyPtPv

Investigation of An Opioid Prescribing Protocol After Third Molar Extraction Procedures

The United States is experiencing an epidemic of opioid overdoses and deaths. The relationship between prescription opioids and opioid abuse is well- documented. Oral and maxillofacial surgeons and other dentists are proportionately among the most prevalent prescribers of opioids. Practitioners are looking for evidence-based ways to decrease excess opioid prescriptions while adequately managing postoperative pain. We recently analyzed the impact of a mandated non-opioid prescribing protocol at our institution.

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The importance of recognizing an association between obstructive sleep apnea and post-traumatic stress disorder (Arthur Friedlander, et al), November 2018, V76, #11

To the Editor: - The recent article in Perspectives section of the journal on recognizing an association between obstructive sleep apnea and post-traumatic stress disorder by Friedlander et al (1) was a new and interesting view on the link between two, not traditionally associated, conditions. Authors indicated the still unknown nature of this association among a selected group of patients, especially military veterans. According to presented literature, possible connections between OSA and PTSD can be attributed to either typical for OSA fragmented sleep pattern with arousals coinciding with decreased airway muscle tone that is also common for disturbing dreams and unstable upper airways of PTSD, dysfunctional REM sleep mechanism and nightmare episodes demonstrated in both disorders, and other causes.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QyPtPv

Investigation of An Opioid Prescribing Protocol After Third Molar Extraction Procedures

The United States is experiencing an epidemic of opioid overdoses and deaths. The relationship between prescription opioids and opioid abuse is well- documented. Oral and maxillofacial surgeons and other dentists are proportionately among the most prevalent prescribers of opioids. Practitioners are looking for evidence-based ways to decrease excess opioid prescriptions while adequately managing postoperative pain. We recently analyzed the impact of a mandated non-opioid prescribing protocol at our institution.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QD7oVh

Is maxillomandibular advancement associated with comorbidity reduction in patients with obstructive sleep apnea?

In patients with documented obstructive sleep apnea (OSA) who experience reduction in AHI and self-reported symptoms after maxillomandibular advancement with genial tubercle advancement (MMA/GTA), is there also a change in the medical comorbidity profile a minimum of two years postoperatively? We are assessing for changes in: the quantity of medical diagnoses; the quantity of prescription medications; and the average weight and BMI.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Bpu5lt

Response to Letter to the Editor - RE: Overutilization of Computed Tomography for Odontogenic Infections

I am writing in response to the Letter to the Editor by Dr. Saggese, regarding our paper titled "Overutilization of Computed Tomography for Odontogenic Infections". First, responding to your concern about our claim of no other published papers investigating computed tomography (CT) overuse for odontogenic infections, this was an accurate claim at the time of the article's initial submission.

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Steven Wayne McCracken | Obituaries - Richland Source

Steven Wayne McCracken | Obituaries  Richland Source

Steven Wayne McCracken, 66, of Galion, Ohio, passed away Friday morning, Dec. 14, 2018, surrounded by his family.

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Liz hits her target - Liverpool City Champion

Liz hits her target  Liverpool City Champion

It would be remiss not to use an archery term to describe Elizabeth Hole's magical 2018 – especially when it sums it up so perfectly.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A2B0kK

Response to Letter to the Editor - RE: Overutilization of Computed Tomography for Odontogenic Infections

I am writing in response to the Letter to the Editor by Dr. Saggese, regarding our paper titled "Overutilization of Computed Tomography for Odontogenic Infections". First, responding to your concern about our claim of no other published papers investigating computed tomography (CT) overuse for odontogenic infections, this was an accurate claim at the time of the article's initial submission.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BvI210

Former Norwich resident awarded additional $44 million in tobacco lawsuit - theday.com

Former Norwich resident awarded additional $44 million in tobacco lawsuit  theday.com

U.S. District Judge Stefan R. Underhill has added $44 million in damages and interest to the nearly $8 million a jury awarded to former Norwich resident Barbara ...

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Steven Wayne McCracken | Obituaries - Richland Source

Steven Wayne McCracken | Obituaries  Richland Source

Steven Wayne McCracken, 66, of Galion, Ohio, passed away Friday morning, Dec. 14, 2018, surrounded by his family.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SVSmGW

Liz hits her target - Liverpool City Champion

Liz hits her target  Liverpool City Champion

It would be remiss not to use an archery term to describe Elizabeth Hole's magical 2018 – especially when it sums it up so perfectly.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A2B0kK

Is maxillomandibular advancement associated with comorbidity reduction in patients with obstructive sleep apnea?

In patients with documented obstructive sleep apnea (OSA) who experience reduction in AHI and self-reported symptoms after maxillomandibular advancement with genial tubercle advancement (MMA/GTA), is there also a change in the medical comorbidity profile a minimum of two years postoperatively? We are assessing for changes in: the quantity of medical diagnoses; the quantity of prescription medications; and the average weight and BMI.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Bpu5lt

Response to Letter to the Editor - RE: Overutilization of Computed Tomography for Odontogenic Infections

I am writing in response to the Letter to the Editor by Dr. Saggese, regarding our paper titled "Overutilization of Computed Tomography for Odontogenic Infections". First, responding to your concern about our claim of no other published papers investigating computed tomography (CT) overuse for odontogenic infections, this was an accurate claim at the time of the article's initial submission.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BvI210

The importance of recognizing an association between obstructive sleep apnea and post-traumatic stress disorder (Arthur Friedlander, et al), November 2018, V76, #11

To the Editor: - The recent article in Perspectives section of the journal on recognizing an association between obstructive sleep apnea and post-traumatic stress disorder by Friedlander et al (1) was a new and interesting view on the link between two, not traditionally associated, conditions. Authors indicated the still unknown nature of this association among a selected group of patients, especially military veterans. According to presented literature, possible connections between OSA and PTSD can be attributed to either typical for OSA fragmented sleep pattern with arousals coinciding with decreased airway muscle tone that is also common for disturbing dreams and unstable upper airways of PTSD, dysfunctional REM sleep mechanism and nightmare episodes demonstrated in both disorders, and other causes.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QyPtPv

Lupus tied to increased cancer risk - medwireNews

Lupus tied to increased cancer risk  medwireNews

Meta-analysis: Lupus associated with an increased risk for 16 types of cancer.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SS3h4j

Innovation Pharmaceuticals Completes End-of-Phase 2 Meeting with FDA; Brilacidin Oral Rinse to Advance Into Phase 3 Clinical Trials for Prevention of Severe Oral Mucositis - Associated Press

Innovation Pharmaceuticals Completes End-of-Phase 2 Meeting with FDA; Brilacidin Oral Rinse to Advance Into Phase 3 Clinical Trials for Prevention of Severe Oral Mucositis  Associated Press

BEVERLY, Mass., Dec. 17, 2018 (GLOBE NEWSWIRE) -- Innovation Pharmaceuticals (OTCQB:IPIX) ("the Company"), a clinical stage pharmaceutical company, ...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2CiDdtv

Study: Immunotherapy Better than Chemotherapy for Subtype of Head and Neck Cancer - UC San Diego Health

Study: Immunotherapy Better than Chemotherapy for Subtype of Head and Neck Cancer  UC San Diego Health

A randomized clinical trial involving 97 medical centers in 20 countries, including Moores Cancer Center at UC San Diego Health, found that treating patients ...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0XyF1

Lupus tied to increased cancer risk - medwireNews

Lupus tied to increased cancer risk  medwireNews

Meta-analysis: Lupus associated with an increased risk for 16 types of cancer.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SS3h4j

Innovation Pharmaceuticals Completes End-of-Phase 2 Meeting with FDA; Brilacidin Oral Rinse to Advance Into Phase 3 Clinical Trials for Prevention of Severe Oral Mucositis - Associated Press

Innovation Pharmaceuticals Completes End-of-Phase 2 Meeting with FDA; Brilacidin Oral Rinse to Advance Into Phase 3 Clinical Trials for Prevention of Severe Oral Mucositis  Associated Press

BEVERLY, Mass., Dec. 17, 2018 (GLOBE NEWSWIRE) -- Innovation Pharmaceuticals (OTCQB:IPIX) ("the Company"), a clinical stage pharmaceutical company, ...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2CiDdtv

Study: Immunotherapy Better than Chemotherapy for Subtype of Head and Neck Cancer - UC San Diego Health

Study: Immunotherapy Better than Chemotherapy for Subtype of Head and Neck Cancer  UC San Diego Health

A randomized clinical trial involving 97 medical centers in 20 countries, including Moores Cancer Center at UC San Diego Health, found that treating patients ...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0XyF1

“Aesthetic abdominoplasty has a positive impact on quality of life prospectively”

In the previous retrospective study we detected an increased quality of life after aesthetic abdominoplasty. In this survey we analyzed quality of life, self-esteem, emotional stability and mental health before and after aesthetic abdominoplasty prospectively.

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“Aesthetic abdominoplasty has a positive impact on quality of life prospectively”

In the previous retrospective study we detected an increased quality of life after aesthetic abdominoplasty. In this survey we analyzed quality of life, self-esteem, emotional stability and mental health before and after aesthetic abdominoplasty prospectively.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Qz2Y1H

Re: Overdiagnosis and industry influence: how cow ’s milk protein allergy is extending the reach of infant formula manufacturers

(Source: BMJ Comments)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

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Re: Overdiagnosis and industry influence: how cow ’s milk protein allergy is extending the reach of infant formula manufacturers

(Source: BMJ Comments)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ChNu9o

SMVD Narayana Hospital organises Masterclass on Head & Neck Oncology - Daily Excelsior

SMVD Narayana Hospital organises Masterclass on Head & Neck Oncology  Daily Excelsior

Excelsior Correspondent KATRA, Dec 17: The Institute of Oncology at Shri Mata Vaishno Devi Narayana Superspeciality Hospital successfully organised its.

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SMVD Narayana Hospital organises Masterclass on Head & Neck Oncology - Daily Excelsior

SMVD Narayana Hospital organises Masterclass on Head & Neck Oncology  Daily Excelsior

Excelsior Correspondent KATRA, Dec 17: The Institute of Oncology at Shri Mata Vaishno Devi Narayana Superspeciality Hospital successfully organised its.

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Acknowledgements to Reviewers

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

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A Mixture of Five Bacterial Strains Attenuates Skin Inflammation in Mice

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2UO6GTu

Natural Phenolics as Inhibitors of the Human Neutrophil Elastase (HNE) Release: An Overview of Natural Anti-inflammatory Discoveries during Recent Years

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S79lpB

Synthesis, In-vivo and In-vitro Anti-inflammatory Evaluation of some Novel Coumarin Derivatives

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6kRKV

Antiallergy Drugs as Potent Inhibitors of Lipase with Structure-activity Relationships and Molecular Docking

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PMyZOE

Synthesis and Biological Evaluation of Novel 2-(4-acetyl-3-methyl-5-(arylamino) thiophen-2-yl)-3-arylquinazolin-4(3H)-one Derivatives as Potential Anti-inflammatory and Antioxidant Agents

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6qMj0

Meet Our Editorial Board Member

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

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Graphical Abstracts

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

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Acknowledgements to Reviewers

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S796eb

A Mixture of Five Bacterial Strains Attenuates Skin Inflammation in Mice

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2UO6GTu

Natural Phenolics as Inhibitors of the Human Neutrophil Elastase (HNE) Release: An Overview of Natural Anti-inflammatory Discoveries during Recent Years

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S79lpB

Synthesis, In-vivo and In-vitro Anti-inflammatory Evaluation of some Novel Coumarin Derivatives

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6kRKV

Antiallergy Drugs as Potent Inhibitors of Lipase with Structure-activity Relationships and Molecular Docking

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PMyZOE

Synthesis and Biological Evaluation of Novel 2-(4-acetyl-3-methyl-5-(arylamino) thiophen-2-yl)-3-arylquinazolin-4(3H)-one Derivatives as Potential Anti-inflammatory and Antioxidant Agents

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6qMj0

Meet Our Editorial Board Member

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2URWw49

Graphical Abstracts

(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6qN6y

Psychometric characteristics of the FertiQoL questionnaire in a German sample of infertile individuals and couples.

FertiQoL is a questionnaire internationally developed to measure fertility-specific quality of life. It has been validated with infertile populations in many countries and used in several studies focusing on t...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2LkZNVk

Cross-cultural adaptation and psychometric evaluation of the early childhood oral health impact scale (ECOHIS) in chilean population

The Early Childhood Oral Health Impact Scale (ECOHIS) measures the impact of dental diseases on Oral Health-Related Quality of Life both in children and their families. The aim of this study was to develop a C...

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Towards Understanding the Molecular Basis of Nitric Oxide-Regulated Group Behaviors in Pathogenic Bacteria

Pathogenic bacteria have many strategies for causing disease in humans. One such strategy is the ability to live both as single-celled motile organisms or as part of a community of bacteria called a biofilm. Biofilms are frequently adhered to biotic or abiotic surfaces and are extremely antibiotic resistant. Upon biofilm dispersal, bacteria become more antibiotic susceptible but are also able to readily infect another host. Various studies have shown that low, nontoxic levels of nitric oxide (NO) may induce biofilm dispersal in many bacterial species. While the molecular details of this phenotype remain largely unknown, in several species, NO has been implicated in biofilm-to-planktonic cell transitions via ligation to 1 of 2 characterized NO sensors, NosP or H-NOX. Based on the data avail...

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Controversies in Drug Allergy: Drug Allergy Pathways

We describe the key patient and institutional factors that must be considered in risk stratification, the central feature of pathway design. We detail shared obstacles to widespread beta-lactam allergy pathway implementation and identify potential solutions to address these challenges. (Source: The Journal of Allergy and Clinical Immunology: In Practice)

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Autoimmune pancreatitis in children: The impact of immune system in a challenging disease

Publication date: Available online 17 December 2018Source: Autoimmunity ReviewsAuthor(s): Danilo Pagliari, Rossella Cianci, Donato Rigante (Source: Autoimmunity Reviews)

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Transient receptor potential ankyrin 1 (trpa1) mediates il-1 β-induced apoptosis in rat chondrocytes via calcium overload and mitochondrial dysfunction

Chondrocyte apoptosis is a central feature in the progression of osteoarthritis (OA), and would be triggered by sustained elevation of intracellular calcium ion (Ca2+), also known as a cellular second messenger. ... (Source: Journal of Inflammation)

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The association between longer relative leukocyte telomere length and risk of glioma is independent of the potentially confounding factors allergy, BMI, and smoking

ConclusionsIn this Swedish glioma case –control cohort, we identified that long rLTL increases the risk of glioma, an association not confounded by allergy, BMI, or smoking. This highlights the complex interplay of the immune system, rLTL and cancer risk. (Source: Cancer Causes and Control)

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Controversies in drug allergy: In vitro testing

Despite their low frequency, drug hypersensitivity reactions (DHRs) can be serious and result in lifelong sequelae. The diagnosis is critical to avert future reactions and should identify the culprit drug or drugs and safe alternatives. However, making the diagnosis can be complex and challenging. Reliable in  vitro tests can offer the potential to improve a diagnosis of DHR and influence medical decision making. Importantly, in vitro testing is frequently not performed as a test in isolation but rather as a component of a diagnostic algorithm along with additional tests. (Source: Journal of Allergy and Clinical Immunology)

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Controversies in drug allergy: Testing for delayed reactions

Controversies exist with regard to in  vivo approaches to delayed immunologically mediated adverse drug reactions, such as exanthem (maculopapular eruption), drug reaction with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome/toxic epidermal necrolysis, and fixed drug eruptions. I n particular, widespread differences exist between regions and practice on the availability and use of intradermal and patch testing, the standard drug concentrations used, the use of additional drugs in intradermal and patch testing to help determine cross-reactivity, the timing of testing in relat ion to the occurrence of the adverse drug reaction, the use of testing in specific phenotypes, and the use of oral challenge in conjunction with delayed intrade...

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

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Anti-SIRT1 autoantibody is elevated in ankylosing spondylitis: a potential disease biomarker

Little is known about the presence of specific autoantibodies in ankylosing spondylitis (AS), an immune-mediated inflammatory disease. The object of this study was to explore potential autoantibody profiles in... (Source: BMC Immunology)

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Prevalence and associated factors of treatment failure among HIV/AIDS patients on HAART attending University of Gondar Referral Hospital Northwest Ethiopia

The initiation of highly active antiretroviral therapy (HAART) plays a significant role in the clinical management of HIV infected people by preventing morbidity and mortality. This benefit becomes, the most t... (Source: BMC Immunology)

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India- Radiotherapy Market Ready to Booming Healthcare Sector with 7% CAGR during 2017 - 2023| Market Research Future® - MENAFN.COM

India- Radiotherapy Market Ready to Booming Healthcare Sector with 7% CAGR during 2017 - 2023| Market Research Future®  MENAFN.COM

(MENAFN - GetNews) Market Research Future has recently share information about global Radiotherapy Market And about the predictions and related market.

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Response Genetics (RGDXQ) and Vermillion (VRML) Financial Contrast - Baseball Daily News

Response Genetics (RGDXQ) and Vermillion (VRML) Financial Contrast  Baseball Daily News

Response Genetics (OTCMKTS:RGDXQ) and Vermillion (NASDAQ:VRML) are both small-cap medical companies, but which is the better investment? We will ...

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Psychometric characteristics of the FertiQoL questionnaire in a German sample of infertile individuals and couples.

FertiQoL is a questionnaire internationally developed to measure fertility-specific quality of life. It has been validated with infertile populations in many countries and used in several studies focusing on t...

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Cross-cultural adaptation and psychometric evaluation of the early childhood oral health impact scale (ECOHIS) in chilean population

The Early Childhood Oral Health Impact Scale (ECOHIS) measures the impact of dental diseases on Oral Health-Related Quality of Life both in children and their families. The aim of this study was to develop a C...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2rH26JB

Towards Understanding the Molecular Basis of Nitric Oxide-Regulated Group Behaviors in Pathogenic Bacteria

Pathogenic bacteria have many strategies for causing disease in humans. One such strategy is the ability to live both as single-celled motile organisms or as part of a community of bacteria called a biofilm. Biofilms are frequently adhered to biotic or abiotic surfaces and are extremely antibiotic resistant. Upon biofilm dispersal, bacteria become more antibiotic susceptible but are also able to readily infect another host. Various studies have shown that low, nontoxic levels of nitric oxide (NO) may induce biofilm dispersal in many bacterial species. While the molecular details of this phenotype remain largely unknown, in several species, NO has been implicated in biofilm-to-planktonic cell transitions via ligation to 1 of 2 characterized NO sensors, NosP or H-NOX. Based on the data avail...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ChIZf0

Controversies in Drug Allergy: Drug Allergy Pathways

We describe the key patient and institutional factors that must be considered in risk stratification, the central feature of pathway design. We detail shared obstacles to widespread beta-lactam allergy pathway implementation and identify potential solutions to address these challenges. (Source: The Journal of Allergy and Clinical Immunology: In Practice)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SSvHuT

Autoimmune pancreatitis in children: The impact of immune system in a challenging disease

Publication date: Available online 17 December 2018Source: Autoimmunity ReviewsAuthor(s): Danilo Pagliari, Rossella Cianci, Donato Rigante (Source: Autoimmunity Reviews)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Cj6rJ2

Transient receptor potential ankyrin 1 (trpa1) mediates il-1 β-induced apoptosis in rat chondrocytes via calcium overload and mitochondrial dysfunction

Chondrocyte apoptosis is a central feature in the progression of osteoarthritis (OA), and would be triggered by sustained elevation of intracellular calcium ion (Ca2+), also known as a cellular second messenger. ... (Source: Journal of Inflammation)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SOuYuK

The association between longer relative leukocyte telomere length and risk of glioma is independent of the potentially confounding factors allergy, BMI, and smoking

ConclusionsIn this Swedish glioma case –control cohort, we identified that long rLTL increases the risk of glioma, an association not confounded by allergy, BMI, or smoking. This highlights the complex interplay of the immune system, rLTL and cancer risk. (Source: Cancer Causes and Control)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ChITnE

Controversies in drug allergy: In vitro testing

Despite their low frequency, drug hypersensitivity reactions (DHRs) can be serious and result in lifelong sequelae. The diagnosis is critical to avert future reactions and should identify the culprit drug or drugs and safe alternatives. However, making the diagnosis can be complex and challenging. Reliable in  vitro tests can offer the potential to improve a diagnosis of DHR and influence medical decision making. Importantly, in vitro testing is frequently not performed as a test in isolation but rather as a component of a diagnostic algorithm along with additional tests. (Source: Journal of Allergy and Clinical Immunology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SVCh3X

Controversies in drug allergy: Testing for delayed reactions

Controversies exist with regard to in  vivo approaches to delayed immunologically mediated adverse drug reactions, such as exanthem (maculopapular eruption), drug reaction with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome/toxic epidermal necrolysis, and fixed drug eruptions. I n particular, widespread differences exist between regions and practice on the availability and use of intradermal and patch testing, the standard drug concentrations used, the use of additional drugs in intradermal and patch testing to help determine cross-reactivity, the timing of testing in relat ion to the occurrence of the adverse drug reaction, the use of testing in specific phenotypes, and the use of oral challenge in conjunction with delayed intrade...

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2CisRtD

Anti-SIRT1 autoantibody is elevated in ankylosing spondylitis: a potential disease biomarker

Little is known about the presence of specific autoantibodies in ankylosing spondylitis (AS), an immune-mediated inflammatory disease. The object of this study was to explore potential autoantibody profiles in... (Source: BMC Immunology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SZAOtB

Prevalence and associated factors of treatment failure among HIV/AIDS patients on HAART attending University of Gondar Referral Hospital Northwest Ethiopia

The initiation of highly active antiretroviral therapy (HAART) plays a significant role in the clinical management of HIV infected people by preventing morbidity and mortality. This benefit becomes, the most t... (Source: BMC Immunology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2CivP1v

India- Radiotherapy Market Ready to Booming Healthcare Sector with 7% CAGR during 2017 - 2023| Market Research Future® - MENAFN.COM

India- Radiotherapy Market Ready to Booming Healthcare Sector with 7% CAGR during 2017 - 2023| Market Research Future®  MENAFN.COM

(MENAFN - GetNews) Market Research Future has recently share information about global Radiotherapy Market And about the predictions and related market.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2EsMjWo

Response Genetics (RGDXQ) and Vermillion (VRML) Financial Contrast - Baseball Daily News

Response Genetics (RGDXQ) and Vermillion (VRML) Financial Contrast  Baseball Daily News

Response Genetics (OTCMKTS:RGDXQ) and Vermillion (NASDAQ:VRML) are both small-cap medical companies, but which is the better investment? We will ...

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CCR Center for Excellence in Immunology Seminar Series

Date: Monday, 02 25, 2019; Speaker: Yardena Samuels, Ph.D, Professor, Department of Molecular Cell Biology, Weizmann Institute of Science; Building: Building 10 (Clinical Center); 3W-3750 (Source: NIH Calendar of Events)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

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Two cases of Tullio phenomenon in which oval and round window reinforcement surgery was effective

To report the effect of oval and round window reinforcement surgery performed in two patients with the Tullio phenomenon. Case 1: A male with bilateral superior canal dehiscence syndrome. Downbeat nystagmus with leftward horizontal eye movement was recorded in an electronystagmogram using a pure-tone sound of 110dB at 2000 or 4000Hz in the right ear. Case 2: A female who had undergone stapes surgery. Computed tomography revealed an ossicular prosthesis in the vestibule. An audiogram indicated mild to moderate hearing impairment in the right ear.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2EoCHff

CCR Center for Excellence in Immunology Seminar Series

Date: Monday, 02 25, 2019; Speaker: Yardena Samuels, Ph.D, Professor, Department of Molecular Cell Biology, Weizmann Institute of Science; Building: Building 10 (Clinical Center); 3W-3750 (Source: NIH Calendar of Events)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2GxWV8K

Two cases of Tullio phenomenon in which oval and round window reinforcement surgery was effective

To report the effect of oval and round window reinforcement surgery performed in two patients with the Tullio phenomenon. Case 1: A male with bilateral superior canal dehiscence syndrome. Downbeat nystagmus with leftward horizontal eye movement was recorded in an electronystagmogram using a pure-tone sound of 110dB at 2000 or 4000Hz in the right ear. Case 2: A female who had undergone stapes surgery. Computed tomography revealed an ossicular prosthesis in the vestibule. An audiogram indicated mild to moderate hearing impairment in the right ear.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2EoCHff

Mast Cell Granules: Modulating adaptive immune response remotely

(Source: Journal of Allergy and Clinical Immunology)

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Mast Cell Granules: Modulating adaptive immune response remotely

(Source: Journal of Allergy and Clinical Immunology)

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Immunotherapeutic Approaches to the Management of Head and Neck Cancer - Cancer Network

Immunotherapeutic Approaches to the Management of Head and Neck Cancer  Cancer Network

Experts discuss the PD-1 checkpoint inhibitors nivolumab and pembrolizumab in the management of head and neck cancer, and how to choose between them.

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Head and Neck Cancer Drugs/Therapeutics Market Set to Encounter Paramount Growth with Myriad Advances - SmarksOn

Head and Neck Cancer Drugs/Therapeutics Market Set to Encounter Paramount Growth with Myriad Advances  SmarksOn

Market Intelligence Data launched a report, and the title is "Global Head and Neck Cancer Drugs/Therapeutics Market 2018 Insights and Trends". The reputed ...

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Whole Foods Packaging Tests Positive for Cancer-Linked Chemicals - The Strategic Sourceror

Whole Foods Packaging Tests Positive for Cancer-Linked Chemicals  The Strategic Sourceror

Last week, a collection of watchdog groups including Toxic-Free Future and Mind the Store published the results of a study on the packaging offered by five ...

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Deutsche Bank Analysts Give Merck KGaA (FRA:MRK) a €93.00 Price Target - Fairfield Current

Deutsche Bank Analysts Give Merck KGaA (FRA:MRK) a €93.00 Price Target  Fairfield Current

Deutsche Bank set a €93.00 ($108.14) target price on Merck KGaA (FRA:MRK) in a report published on Monday, December 10th. The firm currently has a ...

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