Plasmacytoid cells (PLCs) in salivary pleomorphic adenoma (SPA) are regarded as modified neoplastic myoepithelia and define plasmacytoid myoepithelioma (pMYO). However, histochemically, immunohistochemically and ultrastructurally, PLCs fail to demonstrate frank myogenous properties. Epithelial-mesenchymal transition (EMT) may explain the phenotypes in SPA. Our aim was to evaluate 1) PLCs with accepted or purported myoepithelial and EMT-related markers; and 2) pMYOs for PLAG1 aberrations by FISH.
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Πέμπτη 7 Φεβρουαρίου 2019
Plasmacytoid cells in salivary pleomorphic adenoma. An alternative interpretation of their immunohistochemical characteristics highlights function and capability for epithelial-mesenchymal transition
Eosinophil Peroxidase, GATA3 and T-bet as Tissue Biomarkers in Chronic Rhinosinusitis
Eosinophil peroxidase is a potential biomarker for eosinophilic chronic rhinosinusitis. Th2/Th1 polarization, as measured by GATA3 and T-bet, was not associated with eosinophilia or any clinical or histopathologic feature of chronic rhinosinusitis.
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A Volumetric Survey of Aeroallergens in San Antonio, Texas From 2012-2017: Not All Allergens Fit The Mold
An aeroallergen survey of Texas trees, weeds and grasses does not exist. This is the first survey of the unique pollinating patterns in San Antonio, TX developed to tailor testing and immunotherapy.
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Stensen's duct dilation: case series of minimally invasive treatment
Stensen's duct dilation is a rare condition defined by a global or partial idiopathic dilation of the Stensen's duct. Affected patients usually show either aesthetic features, such as a tubular-shaped swelling in the cheek, or with mildly painful inflammatory episodes. Three women between the ages of 61 and 67 years were diagnosed with Stensen's duct dilatation after sialoMRI. They were treated with botulinum toxin A (BTX-A). Our preliminary results suggest that Botulinum Toxin A was efficient as a suspensive treatment.
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Association of geographic tongue and fissured tongue with ABO blood group among adult psoriasis patients – A novel study from a tertiary care hospital in Saudi Arabia
We aimed to determine if there was any association between geographic tongue and fissured tongue with ABO blood group among adult psoriasis patients in Saudi Arabia.
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Pericoronal radiolucency surrounding an impacted mandibular molar
A 19-year-old female with no significant past medical history was referred to an oral surgeon by her otolaryngologist (ENT) for evaluation of a radiolucency in the right mandible. She had been experiencing right-sided jaw discomfort for 4 months and 2 weeks prior to the date of the biopsy. She was evaluated by the ENT for bilateral tenderness of the ears, which was diagnosed as bilateral temporomandibular joint (TMJ) arthritis. A radiolucency of the right mandible was discovered upon radiographic imaging, which prompted referral to her oral surgeon.
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CLINICO-RADIOLOGICAL FOLLOW UP OF CHERUBISM WITH AGGRESSIVE CHARACTERISTICS: A SERIES OF 3 CASES
Cherubism is a rare autosomal dominant disorder characterized by degradation of bone that is replaced by fibrous tissue containing multinucleated giant cells. It clinically manifests as bilateral mandibular and maxillary enlargement. The recent World Health Organization (WHO) classification of 2017 now lists cherubism as one of the giant cell lesions of the jaws, distinct from fibro-osseous disorders.
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Antibiotic prophylaxis: current recommendations in plastic surgery
Abstract
Background
Guidelines for prophylactic antibiotics in surgery have long been established; however, few have focused on recommendations in plastic surgery. Surgical site infection rates remain low, yet the use of prophylactic antibiotics has surged in the past 30 years. This article summarizes current recommendations of prophylactic antibiotic use to produce consensus guidelines in plastic surgery.
Methods
A literature review was conducted in the PubMed, Cochrane, and Ovid databases and studies were included if randomized controlled trials indicated a statistically significant decrease in surgical site infections. Surveys conducted by the American Society of Plastic Surgeons regarding prophylactic antibiotic use from 1975, 1985, 2000, and 2010 were compiled and analyzed.
Results
Of 143 articles found, nine randomized controlled trials showed a reduction in surgical site infections after antibiotic prophylaxis for specific plastic surgery procedures. There are evidence-based recommendations for prophylactic antibiotics in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. The proportion of plastic surgeons using prophylactic antibiotics has steadily increased from 1975 to 2010 with a significant increase from 2000 to 2010.
Conclusions
Systemic antibiotic prophylaxis is recommended for use in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. Recent surveys indicate that the majority of plastic surgeons continue to use prophylactic antibiotics in clean cases of the hand, face, and body despite recommendations. Additional procedure-specific randomized controlled trials are necessary to provide evidence-based recommendations for antibiotic prophylaxis in plastic surgery.
Level of Evidence: Level IV, risk / prognostic study
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Perception of lexical stress and sentence focus by Korean-speaking and Spanish-speaking L2 learners of English
In this study, 32 Spanish learners of English and 38 Korean learners of English completed a lexical stress and a sentence focus oddity test. The results revealed that having lexical stress and phrasal accent in the L1 facilitates the acquisition of L2 prominence, but that differences in how this information is instantiated in the L1 may have a negative effect in its acquisition. (Source: Language Sciences)
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DYEzug
Anglicisms in German media: Exploring catachrestic and non-catachrestic innovations in radio station imaging
Publication date: Available online 7 February 2019Source: LinguaAuthor(s): Sarah Josefine SchaeferAbstractThis paper explores the usage of catachrestic and non-catachrestic anglicism occurrences in radio station imaging materials. These programme elements are taken from a transcribed radio corpus and analysed by means of examining quantitative data and qualitative interviews with 19 journalists. The linguistic analysis of the station imaging content is grounded in the concept of catachrestic and non-catachrestic anglicisms developed by Onysko and Winter-Froemel (2011), which redefines the traditional distinction of luxury and necessary loans in German.Based on a second study by Winter-Froemel et al. (2014), which analyses reasons for the success of some non-catachrestic anglicisms over oth...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gwxt28
Antibiotic prophylaxis: current recommendations in plastic surgery
Abstract
Background
Guidelines for prophylactic antibiotics in surgery have long been established; however, few have focused on recommendations in plastic surgery. Surgical site infection rates remain low, yet the use of prophylactic antibiotics has surged in the past 30 years. This article summarizes current recommendations of prophylactic antibiotic use to produce consensus guidelines in plastic surgery.
Methods
A literature review was conducted in the PubMed, Cochrane, and Ovid databases and studies were included if randomized controlled trials indicated a statistically significant decrease in surgical site infections. Surveys conducted by the American Society of Plastic Surgeons regarding prophylactic antibiotic use from 1975, 1985, 2000, and 2010 were compiled and analyzed.
Results
Of 143 articles found, nine randomized controlled trials showed a reduction in surgical site infections after antibiotic prophylaxis for specific plastic surgery procedures. There are evidence-based recommendations for prophylactic antibiotics in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. The proportion of plastic surgeons using prophylactic antibiotics has steadily increased from 1975 to 2010 with a significant increase from 2000 to 2010.
Conclusions
Systemic antibiotic prophylaxis is recommended for use in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. Recent surveys indicate that the majority of plastic surgeons continue to use prophylactic antibiotics in clean cases of the hand, face, and body despite recommendations. Additional procedure-specific randomized controlled trials are necessary to provide evidence-based recommendations for antibiotic prophylaxis in plastic surgery.
Level of Evidence: Level IV, risk / prognostic study
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BnCPcE
Perception of lexical stress and sentence focus by Korean-speaking and Spanish-speaking L2 learners of English
In this study, 32 Spanish learners of English and 38 Korean learners of English completed a lexical stress and a sentence focus oddity test. The results revealed that having lexical stress and phrasal accent in the L1 facilitates the acquisition of L2 prominence, but that differences in how this information is instantiated in the L1 may have a negative effect in its acquisition. (Source: Language Sciences)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2DYEzug
Anglicisms in German media: Exploring catachrestic and non-catachrestic innovations in radio station imaging
Publication date: Available online 7 February 2019Source: LinguaAuthor(s): Sarah Josefine SchaeferAbstractThis paper explores the usage of catachrestic and non-catachrestic anglicism occurrences in radio station imaging materials. These programme elements are taken from a transcribed radio corpus and analysed by means of examining quantitative data and qualitative interviews with 19 journalists. The linguistic analysis of the station imaging content is grounded in the concept of catachrestic and non-catachrestic anglicisms developed by Onysko and Winter-Froemel (2011), which redefines the traditional distinction of luxury and necessary loans in German.Based on a second study by Winter-Froemel et al. (2014), which analyses reasons for the success of some non-catachrestic anglicisms over oth...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Gwxt28
Antibiotic prophylaxis: current recommendations in plastic surgery
Abstract
Background
Guidelines for prophylactic antibiotics in surgery have long been established; however, few have focused on recommendations in plastic surgery. Surgical site infection rates remain low, yet the use of prophylactic antibiotics has surged in the past 30 years. This article summarizes current recommendations of prophylactic antibiotic use to produce consensus guidelines in plastic surgery.
Methods
A literature review was conducted in the PubMed, Cochrane, and Ovid databases and studies were included if randomized controlled trials indicated a statistically significant decrease in surgical site infections. Surveys conducted by the American Society of Plastic Surgeons regarding prophylactic antibiotic use from 1975, 1985, 2000, and 2010 were compiled and analyzed.
Results
Of 143 articles found, nine randomized controlled trials showed a reduction in surgical site infections after antibiotic prophylaxis for specific plastic surgery procedures. There are evidence-based recommendations for prophylactic antibiotics in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. The proportion of plastic surgeons using prophylactic antibiotics has steadily increased from 1975 to 2010 with a significant increase from 2000 to 2010.
Conclusions
Systemic antibiotic prophylaxis is recommended for use in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. Recent surveys indicate that the majority of plastic surgeons continue to use prophylactic antibiotics in clean cases of the hand, face, and body despite recommendations. Additional procedure-specific randomized controlled trials are necessary to provide evidence-based recommendations for antibiotic prophylaxis in plastic surgery.
Level of Evidence: Level IV, risk / prognostic study
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BnCPcE
Antibiotic prophylaxis: current recommendations in plastic surgery
Abstract
Background
Guidelines for prophylactic antibiotics in surgery have long been established; however, few have focused on recommendations in plastic surgery. Surgical site infection rates remain low, yet the use of prophylactic antibiotics has surged in the past 30 years. This article summarizes current recommendations of prophylactic antibiotic use to produce consensus guidelines in plastic surgery.
Methods
A literature review was conducted in the PubMed, Cochrane, and Ovid databases and studies were included if randomized controlled trials indicated a statistically significant decrease in surgical site infections. Surveys conducted by the American Society of Plastic Surgeons regarding prophylactic antibiotic use from 1975, 1985, 2000, and 2010 were compiled and analyzed.
Results
Of 143 articles found, nine randomized controlled trials showed a reduction in surgical site infections after antibiotic prophylaxis for specific plastic surgery procedures. There are evidence-based recommendations for prophylactic antibiotics in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. The proportion of plastic surgeons using prophylactic antibiotics has steadily increased from 1975 to 2010 with a significant increase from 2000 to 2010.
Conclusions
Systemic antibiotic prophylaxis is recommended for use in breast surgery, abdominoplasty, contaminated hand or face surgery, prosthetic surgery, rhinoplasty, microsurgery, and acute and burn reconstruction cases. Recent surveys indicate that the majority of plastic surgeons continue to use prophylactic antibiotics in clean cases of the hand, face, and body despite recommendations. Additional procedure-specific randomized controlled trials are necessary to provide evidence-based recommendations for antibiotic prophylaxis in plastic surgery.
Level of Evidence: Level IV, risk / prognostic study
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BnCPcE
Request for Information (RFI): Immunologic Assays for Identifying Correlates of Protection (COP) Against Congenital Cytomegalovirus Transmission and/or Disease
Notice NOT-AI-19-035 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GfE8OG
Pulmatrix wins FDA nod for PhII trial of inhaled anti-fungal therapy
Pulmatrix (NSDQ:PULM) said today that the FDA approved a Phase II trial of the company's inhaled formulation of the anti-fungal drug itraconazole for the treatment of allergic bronchopulmonary aspergillosis in people with asthma. The Lexington, Mass.-based company plans to kick off the trial in the first half of 2019, with top-line data expected in the second quarter of 2020. Get the full story at our sister site, Drug Delivery Business News. The post Pulmatrix wins FDA nod for PhII trial of inhaled anti-fungal therapy appeared first on MassDevice. (Source: Mass Device)
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Study of PrEP and vaginal ring for HIV prevention begins in girls and young women
(NIH/National Institute of Allergy and Infectious Diseases) A clinical trial has begun to examine the safety and use of two HIV prevention tools -- oral pre-exposure prophylaxis (PrEP) and a vaginal ring -- in adolescent girls and young women in southern Africa. Funded by the National Institutes of Health, the trial is designed to contribute to the delivery of safe, effective and desirable choices of HIV prevention methods for adolescent girls and young women, who are disproportionately affected by the HIV epidemic. (Source: EurekAlert! - Infectious and Emerging Diseases)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2UGrJXc
Pulmatrix wins FDA nod for PhII trial of inhaled anti-fungal therapy
Pulmatrix (NSDQ:PULM) said today that the FDA approved a Phase II trial of the company's inhaled formulation of the anti-fungal drug itraconazole for the treatment of allergic bronchopulmonary aspergillosis in people with asthma. The Lexington, Mass.-based company plans to kick off the trial in the first half of 2019, with top-line data expected in the second quarter of 2020. Get the full story at our sister site, Drug Delivery Business News. The post Pulmatrix wins FDA nod for PhII trial of inhaled anti-fungal therapy appeared first on MassDevice. (Source: Mass Device)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2tcEUUa
Study of PrEP and vaginal ring for HIV prevention begins in girls and young women
(NIH/National Institute of Allergy and Infectious Diseases) A clinical trial has begun to examine the safety and use of two HIV prevention tools -- oral pre-exposure prophylaxis (PrEP) and a vaginal ring -- in adolescent girls and young women in southern Africa. Funded by the National Institutes of Health, the trial is designed to contribute to the delivery of safe, effective and desirable choices of HIV prevention methods for adolescent girls and young women, who are disproportionately affected by the HIV epidemic. (Source: EurekAlert! - Infectious and Emerging Diseases)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2UGrJXc
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