We have with great interest read the comment from Liccardi et al1 on our article recently published in the Journal.2 We share the opinion that the male dog allergen Can f 5 is an intriguing molecule that deserves further investigation. Sensitization to Can f 5 has in several studies been shown to play a role in respiratory allergy and it is known that monosensitization to Can f 5 occurs in a considerable proportion of dog dander–sensitized individuals. In the current study of dog dander–sensitized children we found that monosensitization to Can f 5 was associated with a negative nasal provocation test (NPT) result with dog dander extract (odds ratio, 5.78; 95% CI, 1.01-33.0).
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Παρασκευή 8 Φεβρουαρίου 2019
Reply
Can f 5 as a suitable marker of dog allergy: Assess male dog exposure before banning it
We read with interest the excellent article by Käck et al1 focusing on the role of different dog allergens in inducing nasal symptoms as assessed by nasal provocation tests (NPTs). It is well known that a significant percentage of individuals sensitized to dog allergens by skin prick tests do not develop overt respiratory symptoms (asthma and/or rhinitis) after direct dog exposure. For this reason, NPTs can be regarded as the "criterion standard" to clarify whether a sensitization to dog allergens can be regarded clinically relevant.
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In-Vitro Setup to Test Hydroxy-Propyl-Methyl-Cellulose as Allergen Barrier over a Span of 360 Minutes
Powder hydroxy-propyl-methyl-cellulose (pHPMC), insufflated in the nose, swells and makes a gel barrier against offending allergens. Most clinical studies demonstrating efficacy of pHPMC have been done in patients sensitized to grass and birch pollens.We set up an in vitro study to document the reduction by pHPMC of the diffusion in agar of 3 other common allergens.
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Reply
We have with great interest read the comment from Liccardi et al1 on our article recently published in the Journal.2 We share the opinion that the male dog allergen Can f 5 is an intriguing molecule that deserves further investigation. Sensitization to Can f 5 has in several studies been shown to play a role in respiratory allergy and it is known that monosensitization to Can f 5 occurs in a considerable proportion of dog dander–sensitized individuals. In the current study of dog dander–sensitized children we found that monosensitization to Can f 5 was associated with a negative nasal provocation test (NPT) result with dog dander extract (odds ratio, 5.78; 95% CI, 1.01-33.0).
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TKMHo1
Can f 5 as a suitable marker of dog allergy: Assess male dog exposure before banning it
We read with interest the excellent article by Käck et al1 focusing on the role of different dog allergens in inducing nasal symptoms as assessed by nasal provocation tests (NPTs). It is well known that a significant percentage of individuals sensitized to dog allergens by skin prick tests do not develop overt respiratory symptoms (asthma and/or rhinitis) after direct dog exposure. For this reason, NPTs can be regarded as the "criterion standard" to clarify whether a sensitization to dog allergens can be regarded clinically relevant.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BvfXrz
In-Vitro Setup to Test Hydroxy-Propyl-Methyl-Cellulose as Allergen Barrier over a Span of 360 Minutes
Powder hydroxy-propyl-methyl-cellulose (pHPMC), insufflated in the nose, swells and makes a gel barrier against offending allergens. Most clinical studies demonstrating efficacy of pHPMC have been done in patients sensitized to grass and birch pollens.We set up an in vitro study to document the reduction by pHPMC of the diffusion in agar of 3 other common allergens.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TEi0AL
Why salivary diagnostics for dental practices?
Source: www.dentistryiq.com Author: Barbara Kreuger, MA, RDH I recently had the opportunity to visit OralDNA Labs and learn more about the […]
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Chronic Rhinosinusitis May Up Risk for Anxiety, Depression Chronic Rhinosinusitis May Up Risk for Anxiety, Depression
Chronic rhinosinusitis is associated with increased risk for anxiety and depression. An expert says possible causal links are unclear, but he supports mental health screening for these patients.Medscape Medical News (Source: Medscape Allergy Headlines)
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Why salivary diagnostics for dental practices?
Source: www.dentistryiq.com Author: Barbara Kreuger, MA, RDH I recently had the opportunity to visit OralDNA Labs and learn more about the […]
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Chronic Rhinosinusitis May Up Risk for Anxiety, Depression Chronic Rhinosinusitis May Up Risk for Anxiety, Depression
Chronic rhinosinusitis is associated with increased risk for anxiety and depression. An expert says possible causal links are unclear, but he supports mental health screening for these patients.Medscape Medical News (Source: Medscape Allergy Headlines)
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‘They needed something more after treatment’
Source: www.nursingtimes.net Author: Claire Reed Lesley Taylor wanted to examine the lack of support for patients at the end of treatment, […]
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‘They needed something more after treatment’
Source: www.nursingtimes.net Author: Claire Reed Lesley Taylor wanted to examine the lack of support for patients at the end of treatment, […]
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Early Introduction of Egg and Development of Egg Allergy
Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
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Early Introduction of Egg and Development of Egg Allergy
Int Arch Allergy Immunol (Source: International Archives of Allergy and Immunology)
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Towards Health Equity: Deaf Adults & #8217; Engagement in Social e-Health Activities and e-Communication with Health Care Providers
(Source: Journal of Health Communication)
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Towards Health Equity: Deaf Adults & #8217; Engagement in Social e-Health Activities and e-Communication with Health Care Providers
(Source: Journal of Health Communication)
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Comparative analysis of the intervertebral disc signal and annulus changes between immediate and 1-year postoperative MRI after transforaminal endoscopic lumbar discectomy and annuloplasty
Abstract
Purpose
Postoperative magnetic resonance imaging (MRI) after microdiscectomy for lumbar disc herniation frequently shows spinal canal compression by the remaining annulus, which gradually decreases over time. Transforaminal endoscopic lumbar discectomy (TELD) can remove the herniation with minimal trauma to surrounding soft tissue. We aim to identify this remodeling of annulus fibrosus and the change of disc signal after TELD.
Methods
We reviewed patients who underwent TELD. Clinical data obtained were Oswestry disability index (ODI) and visual analog scale (VAS) for back and leg pain. Residual mass signal and disc protrusion size were measured in postoperative MRI.
Results
Thirty-one patients were reviewed. The mean age was 38.3 ± 14.4 years (range 18 to 76 years). ODI was 18.2% at the first follow-up and 12.7% at the last follow-up (p = 0.009). VAS for back and leg pain were 2.0 and 1.0 without significant change during follow-up. Disc protrusion size was reduced by 67.7% at the 1-year follow-up (p < 0.001). The residual mass signals at postoperative day 1 were high in 12 cases, intermediate in 18 cases, and low in1 case. The signal intensity was correlated with the percentage of disc protrusion reduction (p = 0.048). The percentage of disc protrusion reduction correlated with the last follow-up ODI (p = 0.018).
Conclusion
One year after TELD, annulus remodeling was observed with an average of 67.7% of size reduction. The high signal intensity of residual mass at day 1 correlated with disc protrusion reduction at follow-up MRI. The percentage of disc protrusion reduction associated with the ODI at the final follow-up.
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Comparative analysis of the intervertebral disc signal and annulus changes between immediate and 1-year postoperative MRI after transforaminal endoscopic lumbar discectomy and annuloplasty
Abstract
Purpose
Postoperative magnetic resonance imaging (MRI) after microdiscectomy for lumbar disc herniation frequently shows spinal canal compression by the remaining annulus, which gradually decreases over time. Transforaminal endoscopic lumbar discectomy (TELD) can remove the herniation with minimal trauma to surrounding soft tissue. We aim to identify this remodeling of annulus fibrosus and the change of disc signal after TELD.
Methods
We reviewed patients who underwent TELD. Clinical data obtained were Oswestry disability index (ODI) and visual analog scale (VAS) for back and leg pain. Residual mass signal and disc protrusion size were measured in postoperative MRI.
Results
Thirty-one patients were reviewed. The mean age was 38.3 ± 14.4 years (range 18 to 76 years). ODI was 18.2% at the first follow-up and 12.7% at the last follow-up (p = 0.009). VAS for back and leg pain were 2.0 and 1.0 without significant change during follow-up. Disc protrusion size was reduced by 67.7% at the 1-year follow-up (p < 0.001). The residual mass signals at postoperative day 1 were high in 12 cases, intermediate in 18 cases, and low in1 case. The signal intensity was correlated with the percentage of disc protrusion reduction (p = 0.048). The percentage of disc protrusion reduction correlated with the last follow-up ODI (p = 0.018).
Conclusion
One year after TELD, annulus remodeling was observed with an average of 67.7% of size reduction. The high signal intensity of residual mass at day 1 correlated with disc protrusion reduction at follow-up MRI. The percentage of disc protrusion reduction associated with the ODI at the final follow-up.
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Acoustic Discriminability of the Complex Phonation System in !X óõ
In this study, I investigate whether the psychoacoustic model of voice by Kreiman et al. (2014) succeeds at distinguishing six phonation types of !X óõ. Linear discriminant analysis is performed using parameters from the model averaged over the entire vowel as well as for the first and final halves of the vowel. The results indicate very high classification accuracy for all phonation types. Measures averaged over the vowel's entire duration are closely correlated with the discriminant functions, suggesting that they are sufficient for distinguishing even dynamic phonation types. Measures from all classes of parameters are correlated with the linear discriminant functions; in particular, the "strident" vowels, which are harsh in qua lity, are characterized by their noise, changes in...
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Preference organization in English as a Medium of Instruction classrooms in a Turkish higher education setting
This study explores preference organization in an under-researched context, an English as a Medium of Instruction (EMI) setting, and it specifically focuses on how a teacher displays dispreference for preceding learner turns. The data consist of 30 h of video recordings from two EMI classes, which were recorded for an academic term at a university in Turkey. Using Conversation Analysis, we demonstrate that the teacher employs a variety of interactional resources such as changing body position, gaze movements, hedging, and delaying devices to show dispreference for preceding student answers. Based on our empirical analysis, the ways the teacher prioritizes content and task over form/language are illustrated. The analyses also reveal that negotiation of meaning at content level and prod...
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