Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite induced murine asthma model.

CONCLUSIONS AND CLINICAL RELEVANCE: This study suggests that kininogen could contribute to HDM induced rise in Penh independently of allergic lung inflammation. Further research is warranted to confirm these data using invasive measurements of airway responsiveness. PMID: 30358441 [PubMed - as supplied by publisher] (Source: Am J Physiol Lung Ce...)

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