Use of synthetic and biologic DMARDs during pregnancy.

Authors: Balbi GGM, Domingues V, Balbi GGM, De Jesús GR, Levy RA Abstract INTRODUCTION: Since most of the autoimmune diseases (AID) affect mostly women in their fertile years, and fertility is in general preserved, the use of disease modifying anti-rheumatic drugs (DMARDs) during conception, pregnancy and lactation has been a matter of concern in the treatment of women affect by AID. Areas covered: We performed a comprehensive review of the latest and most relevant research papers published in the field and discussed different aspects related to the use of synthetic and biologic disease-modifying antirheumatic drugs (DMARDs) and immunosuppressants in the preconceptional period, during pregnancy and lactation in AID patients, both in males and females. Expert commentary: Active AID...

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