Has TNM 8 had an effect on P16 staining & HPV-PCR Correlation in Head and Neck cancer staging, an 8 month review in Europe's largest pathology department

Introduction/Aims: Staging of Head and Neck Cancers (HNC), have moved on greatly since their first inclusion as "Buccal", "Pharynx" and "Larynx". The staging systems have evolved to incorporate Tumour Biology, Cancer Behaviour and the emergence of new stains of disease. The 8th Edition was introduced on the 1st of January 2018, with many centres including Glasgow phasing its introduction alongside TNM from October 2017. One of three new schema introduced includes HPV p16-mediated oropharyngeal carcinoma (OPC). (Source: The British Journal of Oral and Maxillofacial Surgery)

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