Τετάρτη 19 Δεκεμβρίου 2018

Pre-Clinical Compartmental Pharmacokinetic Modeling of 2-[1-hexyloxyethyl]-2-Devinyl Pyropheophorbide-a (HPPH) a Photosensitizer in Rat Plasma by Validated HPLC Method

Photochem. Photobiol. Sci., 2018, Accepted Manuscript
DOI: 10.1039/C8PP00339D, Paper
Kowthavarapu v Krishna, Ranendra Narayan Saha, Anu Puri, Mathias Viard, Bruce A Shapiro, Sunil Kumar Dubey
A second-generation chlorin-based photosensitizer, 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) has shown tremendous therapeutic potential in clinical trials in treatment of esophageal cancer. Here, we have developed and validated a bioanalytical method for...
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