Δευτέρα 26 Νοεμβρίου 2018

Ergonomic hazards in otolaryngology

Objectives/Hypothesis

To evaluate the presence of postural‐related strain and musculoskeletal discomfort, along with the level of ergonomics training and the availability of ergonomic equipment among otolaryngology surgeons.

Study Design

Intraoperative observations and survey study.

Methods

Using the Rapid Entire Body Assessment score system to identify ergonomic hazards, we conducted intraoperative observations assessing operating room personnel during different otolaryngological subspecialty procedures. Based on these findings, otolaryngology surgeons at a single academic institution in the United States were sent a survey that evaluated ergonomic practice, environmental infrastructure, and prior ergonomic training or education.

Results

A response rate of 69% was obtained from 70 surgeons, with 72.9% of responding surgeons suffering from some level of back pain, with cervical spine pain being the most common. Interestingly, residents were equally affected when compared to more senior surgeons both in subjective survey reports and from observational risk analysis. Furthermore, 43.8% of surgeons reported suffering from the highest level of pain when standing, whereas only 12.5% experienced pain when sitting. Importantly, 10% stated that pain impacted their work. Only 24% of surgeons had any prior ergonomic training or education.

Conclusions

Our data suggest that pain and disability induced by poor ergonomics are widespread among the otolaryngology community and confirm that surgeons rarely receive ergonomic training in the surgical context. Additionally, intraoperative observational findings identified that the majority of observed surgeons display poor posture, particularly a poor cervical angle and use of ergonomic setups, both of which increase ergonomic risk hazard. These data provide guidance for future interventional studies.

Level of Evidence

NA Laryngoscope, 2018



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Isolated Paresis of Laryngeal Adduction: What Are the Laryngoscopic and Stroboscopic Findings?

Objectives/Hypothesis

This study aimed to describe the videolaryngostroboscopic (VLS) findings in a cohort of patients with isolated paresis of laryngeal adduction and identify predictive variables that may be related to voice recovery.

Study Design

Chart review and VLS analysis of dysphonic patients diagnosed with isolated paresis of laryngeal adduction by laryngeal electromyography (LEMG).

Methods

Demographic, clinical, VLS, and LEMG findings were analyzed according to the outcome of dysphonia.

Results

There were 17 patients, 12 males (70.6%), mean age of 46.6 years, with median dysphonia duration of 4 months (range, 1–60 months) included in the study. In all patients, gross movement of both vocal folds were normal. Laryngoscopy showed limited adduction of the ipsilateral ventricular fold, contralateral interarytenoid region deviation, and vocal fold atrophy in 100%, 94.1%, and 76.5% of patients, respectively. VLS findings included: impairment of glottic closure (94.1%), phase asymmetry (94.1%), and reduced mucosal wave on the affected side (76.5%). Predictors of good voice outcome were sudden onset (P = .012), duration of dysphonia on presentation shorter than 5 months (P = .005), and absence of polyphasic potentials on LEMG (P = .041).

Conclusions

Findings on VLS as described suggest isolated paresis of laryngeal adduction and should warrant indication of LEMG for definite diagnosis. Voice improvement may be related to clinical and LEMG findings.

Level of Evidence

4 Laryngoscope, 2018



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Presentation and eustachian tube function test results in children evaluated at a specialty clinic

Objectives/Hypothesis

Interest in eustachian tube (ET) dysfunction (ETD) has increased with the recent Food and Drug Administration approval of a new device for balloon dilation of the ET (BDET) in adults. However, children have been receiving BDET treatment with ET‐specific or sinus balloons around the world and off‐label in the United States for years. It is important, therefore, to understand the manifestations of and methods to verify ETD in children.

Study Design

Retrospective cross‐sectional study.

Methods

This is a retrospective study of clinical presentations and results of ET function (ETF) tests in children referred to the ETD clinic. An otorhinolaryngology exam, nasopharyngeal videoendoscopy of the ET orifices during swallow and maneuvers, and ETF tests, including inflation deflation, forced response test, and pressure chamber tests, were performed as applicable.

Results

Data for 30 children aged 6.2 to 17.3 years (mean = 12.9 ± 2.8 years) were analyzed. Of 60 ears, 19 (31.7%) had an intact tympanic membrane (TM), 16 (26.7%) had a patent and two had a blocked ventilation tube, and 23 (38.3%) had a TM perforation. Endoscopy of the nasopharynx revealed a large amount of secretions in 19/45 (42.2%); ET orifices and mucosal inflammation in 22/45 (48.8%); a large amount of adenoid tissue in the fossa of Rosenmuller was noted in 21/45 (46.7%). ETF tests revealed abnormal active function in 43/54 ears (79.6%) and abnormal passive function in 40/54 ears (74.1%).

Conclusions

ETD in children is often associated with residual or regrowth of adenoids and inflammation. Caution should be taken assigning a uniform phenotype and treatment prior to thorough evaluation and testing.

Level of Evidence

4 Laryngoscope, 2018



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The shifting relationship between weight and pediatric obstructive sleep apnea: A historical review

Objectives

For more than a century, pediatric obstructive sleep apnea (OSA) was associated with failure to thrive. However, that association has faded over the last few decades. A 21st century child with OSA is much more likely to be overweight than underweight. This raises the question: Has pediatric OSA changed over time, or has the rise of childhood obesity in the United States created a new, separate disease? This literature review explores the historical shift in the relationship between weight and OSA, and the associated changes in treatment.

Results

We demonstrate a clear transition in the prevalence of failure to thrive and obesity in the OSA literature in the mid‐2000s. What is less clear is whether these two clinical phenotypes should be considered two distinct diseases, or whether subtle differences in one set of pathophysiologic pathways—adenotonsillar hypertrophy, altered inflammation, and increased energy expenditure—can lead to divergent metabolic outcomes. More research is needed to fully elucidate the pathophysiology of OSA in children with obesity.

Conclusions

We may need new and different treatments for obesity‐associated OSA as adenotonsillectomy—which is effective at reversing failure to thrive in OSA—is not as effective at treating OSA in children with obesity. One option is drug‐induced sleep endoscopy, which could personalize and improve surgical treatment of OSA. There is some evidence that therapies used for OSA in adults (e.g., weight loss and positive airway pressure) are also helpful for overweight/obese children with OSA. Laryngoscope, 2018



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First Case of Allergy to Secondhand Marijuana Reported First Case of Allergy to Secondhand Marijuana Reported

Allergy to marijuana can occur in adults who use it, but researchers are flagging the first report of a young child with a positive allergy test who was exposed only to secondhand smoke.Medscape Medical News (Source: Medscape Allergy Headlines)

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Airborne allergic contact dermatitis caused by wood tars



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Airborne allergic contact dermatitis caused by wood tars



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First Case of Allergy to Secondhand Marijuana Reported First Case of Allergy to Secondhand Marijuana Reported

Allergy to marijuana can occur in adults who use it, but researchers are flagging the first report of a young child with a positive allergy test who was exposed only to secondhand smoke.Medscape Medical News (Source: Medscape Allergy Headlines)

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Deep convolutional neural network-based speech enhancement to improve speech intelligibility and quality for hearing-impaired listeners

AbstractIn this paper, we propose a deep learning-based speech enhancement (DLSE) method to improve speech intelligibility for the hearing-impaired listeners. The algorithm decomposes the noisy speech signal into frames (as features) and feeds them to the deep convolutional neural networks (DCNNs) to produce an estimation of which frequency channels contain more perceptually important information (higher signal-to-noise ratio, SNR). This estimate is used to attenuate noise-dominated and retain speech-dominated cochlear implant (CI) channels for electrical stimulation, as in traditionaln-of-m CI coding strategies. The proposed algorithm was evaluated by measuring the speech-in-noise performance of 12 CI users using two types of background noises such as fan and music sounds. The architectur...

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Wireless binaural hearing aid technology for telephone use and listening in wind noise

. (Source: International Journal of Audiology)

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The relationships among verbal ability, executive function, and theory of mind in young children with cochlear implants

Volume 57, Issue 12, December 2018, Page 875-882 . (Source: International Journal of Audiology)

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International journal of audiology reviewer contact information

. (Source: International Journal of Audiology)

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A preliminary study on time-compressed speech recognition in noise among teenage students who use personal listening devices

. (Source: International Journal of Audiology)

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Marilyn K. Glassberg, MD - Examining the IPF Patient ’s Journey to Diagnosis, Appropriate Therapy, and Overall Individualized Care

Examining the IPF Patient's Journey to Diagnosis, Appropriate Therapy, and Overall Individualized Care (Source: PeerView CME/CE Audio Podcast - Immunology)

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First Case of Allergy to Secondhand Marijuana Reported First Case of Allergy to Secondhand Marijuana Reported

Allergy to marijuana can occur in adults who use it, but researchers are flagging the first report of a young child with a positive allergy test who was exposed only to secondhand smoke.Medscape Medical News (Source: Medscape Allergy Headlines)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P1YxXu

Deep convolutional neural network-based speech enhancement to improve speech intelligibility and quality for hearing-impaired listeners

AbstractIn this paper, we propose a deep learning-based speech enhancement (DLSE) method to improve speech intelligibility for the hearing-impaired listeners. The algorithm decomposes the noisy speech signal into frames (as features) and feeds them to the deep convolutional neural networks (DCNNs) to produce an estimation of which frequency channels contain more perceptually important information (higher signal-to-noise ratio, SNR). This estimate is used to attenuate noise-dominated and retain speech-dominated cochlear implant (CI) channels for electrical stimulation, as in traditionaln-of-m CI coding strategies. The proposed algorithm was evaluated by measuring the speech-in-noise performance of 12 CI users using two types of background noises such as fan and music sounds. The architectur...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zutTkw

Wireless binaural hearing aid technology for telephone use and listening in wind noise

. (Source: International Journal of Audiology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5C77B

The relationships among verbal ability, executive function, and theory of mind in young children with cochlear implants

Volume 57, Issue 12, December 2018, Page 875-882 . (Source: International Journal of Audiology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zqgcTW

International journal of audiology reviewer contact information

. (Source: International Journal of Audiology)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P4CNKG

A preliminary study on time-compressed speech recognition in noise among teenage students who use personal listening devices

. (Source: International Journal of Audiology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ztZ13T

Marilyn K. Glassberg, MD - Examining the IPF Patient ’s Journey to Diagnosis, Appropriate Therapy, and Overall Individualized Care

Examining the IPF Patient's Journey to Diagnosis, Appropriate Therapy, and Overall Individualized Care (Source: PeerView CME/CE Audio Podcast - Immunology)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



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CCR10+ ILC2s with ILC1‐like properties exhibit a protective function in severe allergic asthma

Abstract

Background

We previously showed that patients with severe allergic asthma have high numbers of circulating ILC2s expressing CCR10.

Method

Herein, CCR10+ ILC2s were further analyzed in the blood of healthy individuals or patients with allergic and non−allergic asthma. Characteristics of human CCR10+ and CCR10− ILC2s were assessed by flow cytometry as well as single‐cell multiplex RT‐qPCR. The role of CCR10+ ILC2s in asthma pathophysiology was studied in allergen‐treated mice.

Results

When compared to healthy controls, CCR10+ ILC2s are enriched in the blood of both allergic and non‐allergic severe asthmatic patients, and these cells are recruited to the lungs. Plasma concentrations of the CCR10 ligand CCL27 are significantly increased in severe asthmatics when compared to non‐asthmatic patients. CCR10+ ILC2s secrete little TH2 cytokines, but exhibit ILC1‐like properties, including a capacity to produce IFN‐γ. Also, single cell analysis reveals that the CCR10+ ILC2 subset is enriched in cells expressing Amphiregulin. CCR10+ ILC2s depletion, as well as blocking of IFN‐γ activity, exacerbates airway hyperreactivity in allergen‐challenged mice, providing evidence for a protective role of these cells in allergic inflammation.

Conclusions

Frequencies of circulating CCR10+ ILC2s and CCL27 plasma concentrations represent candidate markers of asthma severity. The characterization of CCR10+ ILC2s in human samples and in mouse asthma models suggests that these cells downregulate allergic inflammation through IFN‐γ production.

This article is protected by copyright. All rights reserved.



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RNA is taking its Toll – Impact of RNA‐specific Toll‐like receptors on health and disease

Abstract

RNA‐sensing Toll‐like receptors (TLRs) are often described as anti‐viral receptors of the innate immune system. However, the past decade has shown that the function and importance of these receptors is far more complex. These receptors were found to be relevant for the detection of various bacterial, archaeal, and eukaryotic microorganisms and facilitate the discrimination between dead and living microbes. The cytokine and interferon response profile that is triggered has the potential to improve the efficacy of next‐generation vaccines and may prevent the development of asthma and allergy. Nevertheless, the ability to recognize foreign RNA comes with a cost as also damaged host cells can release nucleic acids that might induce an inappropriate immune response. Thus, it is not surprising that RNA‐sensing TLRs play a key role in various autoimmune diseases. However, promising new inhibitors and antagonists are on the horizon to improve their treatment.

This article is protected by copyright. All rights reserved.



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All items of the Food Allergy Quality of Life Questionnaires are relevant for peanut‐allergic patients



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CCR10+ ILC2s with ILC1‐like properties exhibit a protective function in severe allergic asthma

Abstract

Background

We previously showed that patients with severe allergic asthma have high numbers of circulating ILC2s expressing CCR10.

Method

Herein, CCR10+ ILC2s were further analyzed in the blood of healthy individuals or patients with allergic and non−allergic asthma. Characteristics of human CCR10+ and CCR10− ILC2s were assessed by flow cytometry as well as single‐cell multiplex RT‐qPCR. The role of CCR10+ ILC2s in asthma pathophysiology was studied in allergen‐treated mice.

Results

When compared to healthy controls, CCR10+ ILC2s are enriched in the blood of both allergic and non‐allergic severe asthmatic patients, and these cells are recruited to the lungs. Plasma concentrations of the CCR10 ligand CCL27 are significantly increased in severe asthmatics when compared to non‐asthmatic patients. CCR10+ ILC2s secrete little TH2 cytokines, but exhibit ILC1‐like properties, including a capacity to produce IFN‐γ. Also, single cell analysis reveals that the CCR10+ ILC2 subset is enriched in cells expressing Amphiregulin. CCR10+ ILC2s depletion, as well as blocking of IFN‐γ activity, exacerbates airway hyperreactivity in allergen‐challenged mice, providing evidence for a protective role of these cells in allergic inflammation.

Conclusions

Frequencies of circulating CCR10+ ILC2s and CCL27 plasma concentrations represent candidate markers of asthma severity. The characterization of CCR10+ ILC2s in human samples and in mouse asthma models suggests that these cells downregulate allergic inflammation through IFN‐γ production.

This article is protected by copyright. All rights reserved.



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RNA is taking its Toll – Impact of RNA‐specific Toll‐like receptors on health and disease

Abstract

RNA‐sensing Toll‐like receptors (TLRs) are often described as anti‐viral receptors of the innate immune system. However, the past decade has shown that the function and importance of these receptors is far more complex. These receptors were found to be relevant for the detection of various bacterial, archaeal, and eukaryotic microorganisms and facilitate the discrimination between dead and living microbes. The cytokine and interferon response profile that is triggered has the potential to improve the efficacy of next‐generation vaccines and may prevent the development of asthma and allergy. Nevertheless, the ability to recognize foreign RNA comes with a cost as also damaged host cells can release nucleic acids that might induce an inappropriate immune response. Thus, it is not surprising that RNA‐sensing TLRs play a key role in various autoimmune diseases. However, promising new inhibitors and antagonists are on the horizon to improve their treatment.

This article is protected by copyright. All rights reserved.



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All items of the Food Allergy Quality of Life Questionnaires are relevant for peanut‐allergic patients



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The Optimal Timing of Secondary Alveolar Bone Grafting: A Literature Review

Secondary alveolar bone grafting (SABG) during mixed dentition is the standard of care for alveolar clefts. However, early SABG at the age of 4-7 years before the eruption of lateral incisors versus late SABG at the age of 8-12 years before the eruption of maxillary permanent canines is still debated.The purpose of this study is to perform a systematic review of the literature to evaluate the outcomes of early SABG in terms of residual bone volume or degree of bone resorption, maxillary canine movement or impaction rate, complications, aesthetic outcomes, and compare outcomes of early versus late SABG.

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Do vertical soft-tissue and actual bony landmarks correlate in Le Fort I orthognathic surgery?

Vertical changes in LeFort I orthognathic surgery are critical to the overall aesthetic result. 3D planning enables vertical measurements from the rendered CT scan, but intraoperative points are ascribed partially from soft tissues landmarks. This study compares intraoperative soft tissue vertical measurements with pre- and postoperative CT-based values, and attempts to validate intraoperative soft tissue landmarks for vertical positioning.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P3ePiY

Medicare in Oral and Maxillofacial Surgery Part 2: Academic Surgeons and Cancer Surgeons are Reimbursed Less

To evaluate predictors of reimbursement of oral and maxillofacial surgery services in the Medicare population.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zpgg63

Remarkable short-term regression of a posterior mediastinum metastasis from primary intraosseous carcinoma treated with nivolumab: a case report

Primary intraosseous carcinoma (PIOC, NOS) is a rare odontogenic malignancy that is thought to arise from the odontogenic epithelium. In addition, some cases arise in odontogenic cysts or other benign precursors. There are no established treatment protocols for PIOC because of its rarity. In particular, no standard therapy has been established for patients with recurrent or metastatic PIOC. Here we report a case in which the use of nivolumab showed a significant treatment response in metastatic PIOC.

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Piezosurgery vs. Conventional Osteotomy in Impacted Lower Third Molar Extraction: Evaluation of Perioperative Anxiety, Pain and Paresthesia

Piezoelectric surgery is a safe and effective osteotomy technique that can decrease the perioperative complications and morbidity in oral-maxillofacial surgery. In this study, we compare piezosurgery and conventional rotary technique in the removal of impacted lower third molars. Our primary end points were perioperative anxiety, pain and postoperative discomfort while avoiding the drilling sound of the conventional instrument.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zuYYof

Delayed Pharyngeal Migration of a Mandibular Fixation Screw 30 Years After Orthognathic Surgery

Orthognathic surgery is a commonly performed operation used for correction of dentofacial abnormalities [1]. The operation involves osteotomies and realignment of the maxilla and/or mandible. Common procedures during orthognathic surgery include a LeFort 1 osteotomy, bilateral sagittal split osteotomies (BSSO), and not infrequently a genioplasty.

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Are facial asymmetry and condylar displacement associated with ramus height and treatment outcomes in unilateral condylar fracture when managed by closed method?

This study measures the mandibular ramal height in patients with unilateral condylar fracture managed by closed method using elastic intermaxillary fixation (IMF). It's co-relation with facial asymmetry and condylar displacement were assessed. This will determine whether the treatment outcome is in favour of closed or open method.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zr6Bfy

Intraoperative ultrasound control of zygomatic arch fractures: Does additional imaging improves reduction quality?

Intraoperative navigation to assess anatomic reduction is the general trend in maxillofacial trauma surgery. Aim of this study was to evaluate closed reduction outcome of isolated zygomatic arch fractures using ultrasound compared to palpation control.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P29xEf

Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts

Introduction: Wide alveolar clefts are challenging to treat and are often associated with a higher chance of failure requiring repeated bone grafts. Even if successful, an excessively large cleft leads to a wide edentulous space, and patients are faced with prolonged orthodontic treatment. We present a series of large alveolar clefts closed with the aid of segmental maxillary osteotomies. Cases of alveolar clefts treated by segmental maxillary osteotomy were reviewed from 2014-2016. Preoperative and postoperative CTs were analyzed to assess alveolar gap and bone fill.

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The role of salivary duct morphology in the etiology of chronic obstructive parotitis: statistical analysis of sialographic features and computational fluid dynamics analysis of salivary flow

The causes of some cases of chronic obstructive parotitis (COP) without obstructive factors are still unclear. We hypothesized that some morphological features of salivary ducts might contribute to development of COP. This study aims to investigate the role of salivary duct morphology in the etiology of COP.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P0ZHm8

In Reply to Letter to the Editor

We thank Dr. Tomsic for her appreciation of our article (1). She reiterates the claim that academic productivity is not held in high regard in many of the oral and maxillofacial surgery training programs. Furthermore, Dr. Tomsic points out that the lack of clear academic guidelines from the Commission on Dental Accreditation (CODA) does not aid the specialty in its pursuit of academic advancement. We agree with her claims and are quite optimistic that times will change with regard to this stagnating phenomenon.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zvpTjP

The Optimal Timing of Secondary Alveolar Bone Grafting: A Literature Review

Secondary alveolar bone grafting (SABG) during mixed dentition is the standard of care for alveolar clefts. However, early SABG at the age of 4-7 years before the eruption of lateral incisors versus late SABG at the age of 8-12 years before the eruption of maxillary permanent canines is still debated.The purpose of this study is to perform a systematic review of the literature to evaluate the outcomes of early SABG in terms of residual bone volume or degree of bone resorption, maxillary canine movement or impaction rate, complications, aesthetic outcomes, and compare outcomes of early versus late SABG.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zr6HDW

Do vertical soft-tissue and actual bony landmarks correlate in Le Fort I orthognathic surgery?

Vertical changes in LeFort I orthognathic surgery are critical to the overall aesthetic result. 3D planning enables vertical measurements from the rendered CT scan, but intraoperative points are ascribed partially from soft tissues landmarks. This study compares intraoperative soft tissue vertical measurements with pre- and postoperative CT-based values, and attempts to validate intraoperative soft tissue landmarks for vertical positioning.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P3ePiY

Medicare in Oral and Maxillofacial Surgery Part 2: Academic Surgeons and Cancer Surgeons are Reimbursed Less

To evaluate predictors of reimbursement of oral and maxillofacial surgery services in the Medicare population.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zpgg63

Remarkable short-term regression of a posterior mediastinum metastasis from primary intraosseous carcinoma treated with nivolumab: a case report

Primary intraosseous carcinoma (PIOC, NOS) is a rare odontogenic malignancy that is thought to arise from the odontogenic epithelium. In addition, some cases arise in odontogenic cysts or other benign precursors. There are no established treatment protocols for PIOC because of its rarity. In particular, no standard therapy has been established for patients with recurrent or metastatic PIOC. Here we report a case in which the use of nivolumab showed a significant treatment response in metastatic PIOC.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P1Rqyg

Piezosurgery vs. Conventional Osteotomy in Impacted Lower Third Molar Extraction: Evaluation of Perioperative Anxiety, Pain and Paresthesia

Piezoelectric surgery is a safe and effective osteotomy technique that can decrease the perioperative complications and morbidity in oral-maxillofacial surgery. In this study, we compare piezosurgery and conventional rotary technique in the removal of impacted lower third molars. Our primary end points were perioperative anxiety, pain and postoperative discomfort while avoiding the drilling sound of the conventional instrument.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zuYYof

Delayed Pharyngeal Migration of a Mandibular Fixation Screw 30 Years After Orthognathic Surgery

Orthognathic surgery is a commonly performed operation used for correction of dentofacial abnormalities [1]. The operation involves osteotomies and realignment of the maxilla and/or mandible. Common procedures during orthognathic surgery include a LeFort 1 osteotomy, bilateral sagittal split osteotomies (BSSO), and not infrequently a genioplasty.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P29B6X

Are facial asymmetry and condylar displacement associated with ramus height and treatment outcomes in unilateral condylar fracture when managed by closed method?

This study measures the mandibular ramal height in patients with unilateral condylar fracture managed by closed method using elastic intermaxillary fixation (IMF). It's co-relation with facial asymmetry and condylar displacement were assessed. This will determine whether the treatment outcome is in favour of closed or open method.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zr6Bfy

Intraoperative ultrasound control of zygomatic arch fractures: Does additional imaging improves reduction quality?

Intraoperative navigation to assess anatomic reduction is the general trend in maxillofacial trauma surgery. Aim of this study was to evaluate closed reduction outcome of isolated zygomatic arch fractures using ultrasound compared to palpation control.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P29xEf

Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts

Introduction: Wide alveolar clefts are challenging to treat and are often associated with a higher chance of failure requiring repeated bone grafts. Even if successful, an excessively large cleft leads to a wide edentulous space, and patients are faced with prolonged orthodontic treatment. We present a series of large alveolar clefts closed with the aid of segmental maxillary osteotomies. Cases of alveolar clefts treated by segmental maxillary osteotomy were reviewed from 2014-2016. Preoperative and postoperative CTs were analyzed to assess alveolar gap and bone fill.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zmp7pl

The role of salivary duct morphology in the etiology of chronic obstructive parotitis: statistical analysis of sialographic features and computational fluid dynamics analysis of salivary flow

The causes of some cases of chronic obstructive parotitis (COP) without obstructive factors are still unclear. We hypothesized that some morphological features of salivary ducts might contribute to development of COP. This study aims to investigate the role of salivary duct morphology in the etiology of COP.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P0ZHm8

In Reply to Letter to the Editor

We thank Dr. Tomsic for her appreciation of our article (1). She reiterates the claim that academic productivity is not held in high regard in many of the oral and maxillofacial surgery training programs. Furthermore, Dr. Tomsic points out that the lack of clear academic guidelines from the Commission on Dental Accreditation (CODA) does not aid the specialty in its pursuit of academic advancement. We agree with her claims and are quite optimistic that times will change with regard to this stagnating phenomenon.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zvpTjP

Medical News Today: What is FPIES and how does it affect babies?

Food protein-induced enterocolitis syndrome (FPIES) is a type of allergy that affects babies and young children. Symptoms occur after eating certain trigger foods and include recurring severe diarrhea and vomiting. Learn more here. (Source: Health News from Medical News Today)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsfaGV

Medical News Today: What is FPIES and how does it affect babies?

Food protein-induced enterocolitis syndrome (FPIES) is a type of allergy that affects babies and young children. Symptoms occur after eating certain trigger foods and include recurring severe diarrhea and vomiting. Learn more here. (Source: Health News from Medical News Today)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsfaGV

The Optimal Timing of Secondary Alveolar Bone Grafting: A Literature Review

Secondary alveolar bone grafting (SABG) during mixed dentition is the standard of care for alveolar clefts. However, early SABG at the age of 4-7 years before the eruption of lateral incisors versus late SABG at the age of 8-12 years before the eruption of maxillary permanent canines is still debated.The purpose of this study is to perform a systematic review of the literature to evaluate the outcomes of early SABG in terms of residual bone volume or degree of bone resorption, maxillary canine movement or impaction rate, complications, aesthetic outcomes, and compare outcomes of early versus late SABG.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zr6HDW

Do vertical soft-tissue and actual bony landmarks correlate in Le Fort I orthognathic surgery?

Vertical changes in LeFort I orthognathic surgery are critical to the overall aesthetic result. 3D planning enables vertical measurements from the rendered CT scan, but intraoperative points are ascribed partially from soft tissues landmarks. This study compares intraoperative soft tissue vertical measurements with pre- and postoperative CT-based values, and attempts to validate intraoperative soft tissue landmarks for vertical positioning.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P3ePiY

Medicare in Oral and Maxillofacial Surgery Part 2: Academic Surgeons and Cancer Surgeons are Reimbursed Less

To evaluate predictors of reimbursement of oral and maxillofacial surgery services in the Medicare population.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zpgg63

Remarkable short-term regression of a posterior mediastinum metastasis from primary intraosseous carcinoma treated with nivolumab: a case report

Primary intraosseous carcinoma (PIOC, NOS) is a rare odontogenic malignancy that is thought to arise from the odontogenic epithelium. In addition, some cases arise in odontogenic cysts or other benign precursors. There are no established treatment protocols for PIOC because of its rarity. In particular, no standard therapy has been established for patients with recurrent or metastatic PIOC. Here we report a case in which the use of nivolumab showed a significant treatment response in metastatic PIOC.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P1Rqyg

Piezosurgery vs. Conventional Osteotomy in Impacted Lower Third Molar Extraction: Evaluation of Perioperative Anxiety, Pain and Paresthesia

Piezoelectric surgery is a safe and effective osteotomy technique that can decrease the perioperative complications and morbidity in oral-maxillofacial surgery. In this study, we compare piezosurgery and conventional rotary technique in the removal of impacted lower third molars. Our primary end points were perioperative anxiety, pain and postoperative discomfort while avoiding the drilling sound of the conventional instrument.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zuYYof

Delayed Pharyngeal Migration of a Mandibular Fixation Screw 30 Years After Orthognathic Surgery

Orthognathic surgery is a commonly performed operation used for correction of dentofacial abnormalities [1]. The operation involves osteotomies and realignment of the maxilla and/or mandible. Common procedures during orthognathic surgery include a LeFort 1 osteotomy, bilateral sagittal split osteotomies (BSSO), and not infrequently a genioplasty.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P29B6X

Are facial asymmetry and condylar displacement associated with ramus height and treatment outcomes in unilateral condylar fracture when managed by closed method?

This study measures the mandibular ramal height in patients with unilateral condylar fracture managed by closed method using elastic intermaxillary fixation (IMF). It's co-relation with facial asymmetry and condylar displacement were assessed. This will determine whether the treatment outcome is in favour of closed or open method.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zr6Bfy

Intraoperative ultrasound control of zygomatic arch fractures: Does additional imaging improves reduction quality?

Intraoperative navigation to assess anatomic reduction is the general trend in maxillofacial trauma surgery. Aim of this study was to evaluate closed reduction outcome of isolated zygomatic arch fractures using ultrasound compared to palpation control.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P29xEf

Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts

Introduction: Wide alveolar clefts are challenging to treat and are often associated with a higher chance of failure requiring repeated bone grafts. Even if successful, an excessively large cleft leads to a wide edentulous space, and patients are faced with prolonged orthodontic treatment. We present a series of large alveolar clefts closed with the aid of segmental maxillary osteotomies. Cases of alveolar clefts treated by segmental maxillary osteotomy were reviewed from 2014-2016. Preoperative and postoperative CTs were analyzed to assess alveolar gap and bone fill.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zmp7pl

The role of salivary duct morphology in the etiology of chronic obstructive parotitis: statistical analysis of sialographic features and computational fluid dynamics analysis of salivary flow

The causes of some cases of chronic obstructive parotitis (COP) without obstructive factors are still unclear. We hypothesized that some morphological features of salivary ducts might contribute to development of COP. This study aims to investigate the role of salivary duct morphology in the etiology of COP.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P0ZHm8

In Reply to Letter to the Editor

We thank Dr. Tomsic for her appreciation of our article (1). She reiterates the claim that academic productivity is not held in high regard in many of the oral and maxillofacial surgery training programs. Furthermore, Dr. Tomsic points out that the lack of clear academic guidelines from the Commission on Dental Accreditation (CODA) does not aid the specialty in its pursuit of academic advancement. We agree with her claims and are quite optimistic that times will change with regard to this stagnating phenomenon.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zvpTjP

Pigmented villonodular synovitis occurring in the temporomandibular joint

Pigmented villonodular synovitis occurring in the region of the temporomandibular joint is a rare disease, requiring a review of the treatment method, follow-up period.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PYqO6I

The Optimal Timing of Secondary Alveolar Bone Grafting: A Literature Review

Secondary alveolar bone grafting (SABG) during mixed dentition is the standard of care for alveolar clefts. However, early SABG at the age of 4-7 years before the eruption of lateral incisors versus late SABG at the age of 8-12 years before the eruption of maxillary permanent canines is still debated.The purpose of this study is to perform a systematic review of the literature to evaluate the outcomes of early SABG in terms of residual bone volume or degree of bone resorption, maxillary canine movement or impaction rate, complications, aesthetic outcomes, and compare outcomes of early versus late SABG.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zr6HDW

Do vertical soft-tissue and actual bony landmarks correlate in Le Fort I orthognathic surgery?

Vertical changes in LeFort I orthognathic surgery are critical to the overall aesthetic result. 3D planning enables vertical measurements from the rendered CT scan, but intraoperative points are ascribed partially from soft tissues landmarks. This study compares intraoperative soft tissue vertical measurements with pre- and postoperative CT-based values, and attempts to validate intraoperative soft tissue landmarks for vertical positioning.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P3ePiY

Medicare in Oral and Maxillofacial Surgery Part 2: Academic Surgeons and Cancer Surgeons are Reimbursed Less

To evaluate predictors of reimbursement of oral and maxillofacial surgery services in the Medicare population.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zpgg63

Remarkable short-term regression of a posterior mediastinum metastasis from primary intraosseous carcinoma treated with nivolumab: a case report

Primary intraosseous carcinoma (PIOC, NOS) is a rare odontogenic malignancy that is thought to arise from the odontogenic epithelium. In addition, some cases arise in odontogenic cysts or other benign precursors. There are no established treatment protocols for PIOC because of its rarity. In particular, no standard therapy has been established for patients with recurrent or metastatic PIOC. Here we report a case in which the use of nivolumab showed a significant treatment response in metastatic PIOC.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P1Rqyg

Piezosurgery vs. Conventional Osteotomy in Impacted Lower Third Molar Extraction: Evaluation of Perioperative Anxiety, Pain and Paresthesia

Piezoelectric surgery is a safe and effective osteotomy technique that can decrease the perioperative complications and morbidity in oral-maxillofacial surgery. In this study, we compare piezosurgery and conventional rotary technique in the removal of impacted lower third molars. Our primary end points were perioperative anxiety, pain and postoperative discomfort while avoiding the drilling sound of the conventional instrument.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zuYYof

Delayed Pharyngeal Migration of a Mandibular Fixation Screw 30 Years After Orthognathic Surgery

Orthognathic surgery is a commonly performed operation used for correction of dentofacial abnormalities [1]. The operation involves osteotomies and realignment of the maxilla and/or mandible. Common procedures during orthognathic surgery include a LeFort 1 osteotomy, bilateral sagittal split osteotomies (BSSO), and not infrequently a genioplasty.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P29B6X

Are facial asymmetry and condylar displacement associated with ramus height and treatment outcomes in unilateral condylar fracture when managed by closed method?

This study measures the mandibular ramal height in patients with unilateral condylar fracture managed by closed method using elastic intermaxillary fixation (IMF). It's co-relation with facial asymmetry and condylar displacement were assessed. This will determine whether the treatment outcome is in favour of closed or open method.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zr6Bfy

Intraoperative ultrasound control of zygomatic arch fractures: Does additional imaging improves reduction quality?

Intraoperative navigation to assess anatomic reduction is the general trend in maxillofacial trauma surgery. Aim of this study was to evaluate closed reduction outcome of isolated zygomatic arch fractures using ultrasound compared to palpation control.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P29xEf

Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts

Introduction: Wide alveolar clefts are challenging to treat and are often associated with a higher chance of failure requiring repeated bone grafts. Even if successful, an excessively large cleft leads to a wide edentulous space, and patients are faced with prolonged orthodontic treatment. We present a series of large alveolar clefts closed with the aid of segmental maxillary osteotomies. Cases of alveolar clefts treated by segmental maxillary osteotomy were reviewed from 2014-2016. Preoperative and postoperative CTs were analyzed to assess alveolar gap and bone fill.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zmp7pl

The role of salivary duct morphology in the etiology of chronic obstructive parotitis: statistical analysis of sialographic features and computational fluid dynamics analysis of salivary flow

The causes of some cases of chronic obstructive parotitis (COP) without obstructive factors are still unclear. We hypothesized that some morphological features of salivary ducts might contribute to development of COP. This study aims to investigate the role of salivary duct morphology in the etiology of COP.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P0ZHm8

In Reply to Letter to the Editor

We thank Dr. Tomsic for her appreciation of our article (1). She reiterates the claim that academic productivity is not held in high regard in many of the oral and maxillofacial surgery training programs. Furthermore, Dr. Tomsic points out that the lack of clear academic guidelines from the Commission on Dental Accreditation (CODA) does not aid the specialty in its pursuit of academic advancement. We agree with her claims and are quite optimistic that times will change with regard to this stagnating phenomenon.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zvpTjP

Pigmented villonodular synovitis occurring in the temporomandibular joint

Pigmented villonodular synovitis occurring in the region of the temporomandibular joint is a rare disease, requiring a review of the treatment method, follow-up period.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PYqO6I

Medical News Today: What is FPIES and how does it affect babies?

Food protein-induced enterocolitis syndrome (FPIES) is a type of allergy that affects babies and young children. Symptoms occur after eating certain trigger foods and include recurring severe diarrhea and vomiting. Learn more here. (Source: Health News from Medical News Today)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsfaGV

Medical News Today: What is FPIES and how does it affect babies?

Food protein-induced enterocolitis syndrome (FPIES) is a type of allergy that affects babies and young children. Symptoms occur after eating certain trigger foods and include recurring severe diarrhea and vomiting. Learn more here. (Source: Health News from Medical News Today)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsfaGV

Beyond Human Perception: Sexual Dimorphism in Hand and Wrist Radiographs Is Discernible by a Deep Learning Model

Abstract

Despite the well-established impact of sex and sex hormones on bone structure and density, there has been limited description of sexual dimorphism in the hand and wrist in the literature. We developed a deep convolutional neural network (CNN) model to predict sex based on hand radiographs of children and adults aged between 5 and 70 years. Of the 1531 radiographs tested, the algorithm predicted sex correctly in 95.9% (κ = 0.92) of the cases. Two human radiologists achieved 58% (κ = 0.15) and 46% (κ = − 0.07) accuracy. The class activation maps (CAM) showed that the model mostly focused on the 2nd and 3rd metacarpal base or thumb sesamoid in women, and distal radioulnar joint, distal radial physis and epiphysis, or 3rd metacarpophalangeal joint in men. The radiologists reviewed 70 cases (35 females and 35 males) labeled with sex along with heat maps generated by CAM, but they could not find any patterns that distinguish the two sexes. A small sample of patients (n = 44) with sexual developmental disorders or transgender identity was selected for a preliminary exploration of application of the model. The model prediction agreed with phenotypic sex in only 77.8% (κ = 0.54) of these cases. To the best of our knowledge, this is the first study that demonstrated a machine learning model to perform a task in which human experts could not fulfill.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DPnO5t

Beyond Human Perception: Sexual Dimorphism in Hand and Wrist Radiographs Is Discernible by a Deep Learning Model

Abstract

Despite the well-established impact of sex and sex hormones on bone structure and density, there has been limited description of sexual dimorphism in the hand and wrist in the literature. We developed a deep convolutional neural network (CNN) model to predict sex based on hand radiographs of children and adults aged between 5 and 70 years. Of the 1531 radiographs tested, the algorithm predicted sex correctly in 95.9% (κ = 0.92) of the cases. Two human radiologists achieved 58% (κ = 0.15) and 46% (κ = − 0.07) accuracy. The class activation maps (CAM) showed that the model mostly focused on the 2nd and 3rd metacarpal base or thumb sesamoid in women, and distal radioulnar joint, distal radial physis and epiphysis, or 3rd metacarpophalangeal joint in men. The radiologists reviewed 70 cases (35 females and 35 males) labeled with sex along with heat maps generated by CAM, but they could not find any patterns that distinguish the two sexes. A small sample of patients (n = 44) with sexual developmental disorders or transgender identity was selected for a preliminary exploration of application of the model. The model prediction agreed with phenotypic sex in only 77.8% (κ = 0.54) of these cases. To the best of our knowledge, this is the first study that demonstrated a machine learning model to perform a task in which human experts could not fulfill.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DPnO5t

Are antithrombotic agents necessary for head and neck microvascular surgery?

The aim of this prospective study was to determine the effect of antithrombotic agents in preventing thrombosis after head and neck reconstructive surgery. A randomized clinical trial of referred patients undergoing free flap surgery between February 2015 and July 2017 was conducted. Four hundred and fifty-four patients were randomly assigned to group A (n=153), administered aspirin and low molecular weight dextran; group B (n=150), administered low molecular weight heparin; and group C (n=151), not administered any antithrombotic agent.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DMbjas

Towards an asset-based approach to promoting and sustaining well-being for people with aphasia and their families: an international exploratory study

. (Source: Aphasiology)

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Collaborative design of accessible information with people with aphasia

. (Source: Aphasiology)

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The coding of sex in Spanish nouns

Publication date: Available online 24 November 2018Source: LinguaAuthor(s): Carlos-Eduardo PiñerosAbstractTraditional views on how sex is coded in Spanish nouns are revolutionized in this article. To the initial discovery that sex coding yields not only singlets and doublets but also triplets, it is added that Spanish employs three sex coding modes whose productivity correlates with structural cost. The suppletive and the derivational modes require investing in sex-specific morphemes, which makes them costly, whereas the inflectional mode achieves maximal economy by exploiting the exponent of another grammatical category: declension. The transfer of productive sex coding to the grammar is another major innovation. Lexical Specification is appropriate to formalize the suppletive and the de...

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Vicenin-2 ameliorates oxidative damage and photoaging via modulation of MAPKs and MMPs signaling in UVB radiation exposed human skin cells

In this study, UVB-irradiation (100 mJ/cm2) significantly elevated the intracellular ROS levels, lipid peroxidation, DNA damage, depletion of antioxidants resulted in apoptotic HDF cells. Interestingly, HDF cells were administrated with vicenin-2, 1 h before UVB-irradiation prevents ROS generation, TBARS, apoptotic changes and DNA damage in HDF. MAPKs and MMP signaling are implicated in oxidative stress and photoaging; these signaling events are considered as photoaging and differentiation. We found that Vicenin-2 prevents over expression of MAPKs (p-ERK1, p-JNK & p-p38), AP-1 and MMPs (MMP-2, 9 & 12) in during the exposure of UVB in HDF cells. These findings conclude that vicenin-2 could be a potential bioactive ingredient to absorb UV photons and protects the dermal cells from the UV...

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The second-order effect of orthography-to-phonology mapping consistency on Chinese spoken word recognition

Publication date: August 2019Source: Journal of Neurolinguistics, Volume 51Author(s): Pei-Chun Chao, Wei-Fan Chen, Chia-Ying LeeAbstractThe influences of the orthography-to-phonology (O-to-P) mapping consistency as the first-order effect on visual word recognition are well documented. Few studies have investigated the second-order O-to-P consistency effect on spoken word recognition. To address this issue, Experiment 1 asked participants to perform a writing-to-dictation task for 230 Chinese monosyllabic words and found that the response accuracy increased with the homophone density, and the homophone density, O-to-P consistency, and character frequency also affected the generation probability and reaction time of written responses. Experiment 2 involved manipulating the homophone density ...

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Editorial Board

Publication date: December 2018Source: Lingua, Volume 216Author(s): (Source: Lingua)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AohkXG

Development of grammatical voice marking in Korean: On the causative, middle and passive uses of suffix -i

Publication date: Available online 23 November 2018Source: LinguaAuthor(s): Foong Ha Yap, Mikyung AhnAbstractVoice-markers enable speakers to profile a situation/event in ways that reflect their perspective of 'who' or 'what' is being foregrounded as the discourse unfolds. Our diachronic study focuses on how a versatile voice marker evolves new functions as it competes for its semantic niche with other voice markers. Using data from Old Korean texts written in Kukyel and data from Middle and Modern Korean1 texts written in Hankul from the Sejong historical corpus, we show how Korean suffix -i extends from causative to middle and passive uses through reflexive causatives while competing with voice markers -eci and -key ha-. Our analysis reveals: (i) a relaxation of telicity and spec...

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Biosynthesis and characterization of copper oxide nanoparticles from indigenous fungi and its effect of photothermolysis on human lung carcinoma

In this report, copper oxide nanoparticles (TA-CuO NPs) were synthesized using cell-free extract of Trichoderma asperellum and assessed their photothermal induced anticancerous activity. The fungal mediated TA-CuO NPs was confirmed by the surface plasmon resonance at 285–295 nm. The amide (CO) and aromatic (CC) groups in secondary metabolites of the extract was found to be an encapsulating or reducing agents for TA-CuO NPs, as indicated by IR spectra. Crystalline nature by cubic face-centered structure of the TA-CuO NPs was confirmed by XRD and their size ranges from 10 to 190 nm and an average of 110 nm by particle size analyzer (PSA). The Ultra HRSEM study revealed spherical shaped TA-CuO NPs. The FETEM results were also in strong agreement with PSA and UHR SEM. The survey-scan s...

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Concrete and abstract word processing in deep dyslexia

Publication date: Available online 23 November 2018Source: Journal of NeurolinguisticsAuthor(s): Simritpal Kaur Malhi, Tara Lynn McAuley, Brette Lansue, Lori BuchananAbstractThe purpose of this case study was to test the failure of inhibition theory of deep dyslexia (FIT; Buchanan, McEwen, Westbury, & Libben, 2003) with concrete and abstract words. FIT proposes that in deep dyslexia, errors to abstract words are the result of an impairment in phonological output lexicon selection rather than a semantic deficit for abstract words. FIT also proposes a dissociation between explicit phonological lexicon production (can be compromised) and implicit access of representations (is intact). With such assumptions it follows that in phonologically implicit tasks where controls demonstrate either conc...

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The creation of a new vowel category by adult learners after adaptive phonetic training

Publication date: January 2019Source: Journal of Phonetics, Volume 72Author(s): Izabelle Grenon, Mikio Kubota, Chris SheppardAbstractNative Japanese speakers often perceive English vowels based on their duration, whereas native speakers use spectral cues (formant frequencies). The current study examined whether 23 Japanese adult learners of English could create a new vowel category along the spectral dimension after phonetic training with the English vowels /i/-/ɪ/ as in beat and bit. As in previous training studies, the Japanese trainees improved their ability to categorize the vowels in tokens included in the training, and were able to generalize to novel tokens and talkers. A cue-weighting task confirmed that the Japanese trainees categorized the vowels based on temporal cues before tr...

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Anticancer, antimicrobial and photocatalytic activities of green synthesized magnesium oxide nanoparticles (MgONPs) using aqueous extract of Sargassum wightii

Publication date: Available online 23 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Arivalagan Pugazhendhi, Raju Prabhu, Kavitha Muruganantham, Rajasree Shanmuganathan, Suganthy NatarajanAbstractA rapid and ecofriendly fabrication of metal oxide nanoparticles using biogenic sources is the current trend being used to replace the toxic chemical method. The present study was carried out to synthesize magnesium oxide nanoparticles (MgONPs) using the marine brown algae Sargassum wighitii as the reducing and capping agent. The as-prepared MgONPs were characterized by spectroscopic and microscopic analyses. UV–visible spectrum of the MgONPs showed a sharp absorption peak at 322 nm. X- ray diffraction analysis illustrated that the MgONPs were crystalline ...

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Biosynthesized of reduced graphene oxide nanosheets and its loading with paclitaxel for their anti cancer effect for treatment of lung cancer

Publication date: Available online 22 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Shaobing Lin, Junshan Ruan, Shaoming WangAbstractMultifunctional nanocarriers are in immediate need to develop anticancer activity for the treatment of cancers. In the present research, the graphene oxide was reduced via an efficient method which reduced to RGO by using Euphorbia milii leaves extract. Thus obtained RGO nanocomposites were subsequently characterized by means UV–Vis absorption technique. AFM imaging was further performed in order to analyze the surface morphology of GO nanosheet as well as to estimate the average thickness of the GO nanosheets before and after the addition of Euphorbia milii leaves extract. Furthermore, the anticancer effect of RGO-loa...

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Synthesis of cerium oxide nanoparticles loaded on chitosan for enhanced auto-catalytic regenerative ability and biocompatibility for the spinal cord injury repair

Publication date: Available online 22 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Xiutong Fang, Hongxing SongAbstractBiomedical applications like spinal cord injury repair; anticancer requires functional platforms and specific properties like antioxidant, autocatalytic and biocompatibility. This work demonstrated the synthesis of CeO2 nanoparticles which is shown to have promising applications in various fields exclusively biomedical field like scavenging of reactive oxygen species which is mainly responsible for carcinogenic effects. CeO2 nanoparticles were synthesized using the biocompatible ionic liquid followed by their loading with biopolymeric chitosan which was obtained by the deacetylation processing of chitin arrived from the shells of crab...

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‘Invisible minorities’ and ‘hidden diversity’ in Saint-Petersburg's linguistic landscape

Publication date: Available online 23 November 2018Source: Language & CommunicationAuthor(s): Vlada Baranova, Kapitolina FedorovaAbstractThe article deals with representation of labour migrants' languages in St. Petersburg's linguistic landscape. The data analyzed in the article were gathered through fieldwork (in 2016–2017) in different districts of the city. The communication between the majority and ethnic minorities is conducted only in Russian, both in official and in informal exchanges, such as between commercial agencies and non-Russian speakers. Even in places with no official regulation, non-Russian languages' use is significantly rare and occurs predominantly in the frame of in-group communication. Only two languages, Chinese and Uzbek, occasionally can be used in adverti...

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Editorial Board

Publication date: January 2019Source: Language Sciences, Volume 71Author(s): (Source: Language Sciences)

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Look at Mommy: An Exploratory Study of Attention-Related Communication in Mothers of Toddlers at Risk for Autism

. (Source: Language Learning and Development)

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How Children Identify Events from Visual Experience

. (Source: Language Learning and Development)

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Are antithrombotic agents necessary for head and neck microvascular surgery?

The aim of this prospective study was to determine the effect of antithrombotic agents in preventing thrombosis after head and neck reconstructive surgery. A randomized clinical trial of referred patients undergoing free flap surgery between February 2015 and July 2017 was conducted. Four hundred and fifty-four patients were randomly assigned to group A (n=153), administered aspirin and low molecular weight dextran; group B (n=150), administered low molecular weight heparin; and group C (n=151), not administered any antithrombotic agent.

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Towards an asset-based approach to promoting and sustaining well-being for people with aphasia and their families: an international exploratory study

. (Source: Aphasiology)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TLnGt3

Collaborative design of accessible information with people with aphasia

. (Source: Aphasiology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ApBkJs