ConclusionDissemination of some major STs and horizontal transfer of plasmids carrying two major structure types of Tn1546-like elements may have together contributed to the increase of VRE-fm infection. (Source: Journal of Microbiology, Immunology and Infection)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Microbiology and Immunology,Volume 0, Issue ja, -Not available-. (Source: Microbiology and Immunology)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
ConclusionDissemination of some major STs and horizontal transfer of plasmids carrying two major structure types of Tn1546-like elements may have together contributed to the increase of VRE-fm infection. (Source: Journal of Microbiology, Immunology and Infection)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Microbiology and Immunology,Volume 0, Issue ja, -Not available-. (Source: Microbiology and Immunology)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Publication date: Available online 7 September 2018
Source: Annals of Allergy, Asthma & Immunology
Author(s): Michael S. Blaiss, Gary C. Steven, Bruce Bender, Don A. Bukstein, Eli O. Meltzer, Tonya Winders
Publication date: Available online 7 September 2018
Source: Annals of Allergy, Asthma & Immunology
Author(s): David E. Tapke, Rebecca Scherzer, Mitchell H. Grayson
Publication date: Available online 7 September 2018
Source: Annals of Allergy, Asthma & Immunology
Author(s): Michael S. Blaiss, Gary C. Steven, Bruce Bender, Don A. Bukstein, Eli O. Meltzer, Tonya Winders
Publication date: Available online 7 September 2018
Source: Annals of Allergy, Asthma & Immunology
Author(s): David E. Tapke, Rebecca Scherzer, Mitchell H. Grayson
Publication date: Available online 7 September 2018
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases
Author(s): P. Gallet, D.T. Nguyen, A. Russel, R. Jankowski, C. Vigouroux, C. Rumeau
The aim of the present study was to investigate the role of wood dust exposure in intestinal (ITAC) and non-intestinal type (non-ITAC) nasal adenocarcinoma, so as to improve understanding of the oncogenic mechanisms in the light of the recent literature and of evo-devo concepts.
All consecutive patients operated in our institution for nasal adenocarcinoma diagnosed on anatomopathology between May 2004 and February 2014 were included. Surgical specimens were examined twice by independent pathologists, blind to wood dust exposure status. Clinical and demographic data, including wood dust exposure, were collected for the two groups (ITAC and non-IATC).
90 patients (84 ITAC, 6 non-ITAC) were included. No non-ITAC patients had history of wood dust exposure, versus 83/84 cases (99%) in ITAC (mean exposure duration: 30 ± 16 years; range 2–65 years). Only 12 ITAC patients (18%) were still exposed at diagnosis. ITAC may develop long after the end of wood dust exposure (up to 60 years). Eight patients (12%) had exposure durations of less than 5 years. Latency between onset of exposure and onset of disease did not decrease with exposure duration.
Exposure to wood dust, even for short periods of time, incurs a risk of developing ITAC, usually after a long latency period. Any exposure requires lifetime follow-up, to ensure prompt treatment. Factors leading to the development of nasal ITAC and non-ITAC are probably different. The analogy with Barret's esophagus and esophageal adenocarcinoma may shed light on the oncogenesis of nasal ITAC.
Publication date: Available online 7 September 2018
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases
Author(s): P. Gallet, D.T. Nguyen, A. Russel, R. Jankowski, C. Vigouroux, C. Rumeau
The aim of the present study was to investigate the role of wood dust exposure in intestinal (ITAC) and non-intestinal type (non-ITAC) nasal adenocarcinoma, so as to improve understanding of the oncogenic mechanisms in the light of the recent literature and of evo-devo concepts.
All consecutive patients operated in our institution for nasal adenocarcinoma diagnosed on anatomopathology between May 2004 and February 2014 were included. Surgical specimens were examined twice by independent pathologists, blind to wood dust exposure status. Clinical and demographic data, including wood dust exposure, were collected for the two groups (ITAC and non-IATC).
90 patients (84 ITAC, 6 non-ITAC) were included. No non-ITAC patients had history of wood dust exposure, versus 83/84 cases (99%) in ITAC (mean exposure duration: 30 ± 16 years; range 2–65 years). Only 12 ITAC patients (18%) were still exposed at diagnosis. ITAC may develop long after the end of wood dust exposure (up to 60 years). Eight patients (12%) had exposure durations of less than 5 years. Latency between onset of exposure and onset of disease did not decrease with exposure duration.
Exposure to wood dust, even for short periods of time, incurs a risk of developing ITAC, usually after a long latency period. Any exposure requires lifetime follow-up, to ensure prompt treatment. Factors leading to the development of nasal ITAC and non-ITAC are probably different. The analogy with Barret's esophagus and esophageal adenocarcinoma may shed light on the oncogenesis of nasal ITAC.
Publication date: Available online 7 September 2018Source: Fish & Shellfish ImmunologyAuthor(s): Hang Su, Jianguo SuAbstractIn the past decades, global freshwater fish production has been rapidly growing, while cyprinid takes the largest portion. Along with the rapid rise of novel forms of intensive aquaculture, increased global aquatic animal movement and various anthropogenic stress to aquatic ecosystems during the past century, freshwater fish farming industry encounter the emergence and breakout of many diseases, especially viral diseases. Because of the ability to safely and effectively prevent aquaculture diseases, vaccines have become the mainstream technology for prevention and control of aquatic diseases in the world. In this review, authors summarized six major cyprinid viral dis...
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
The objective of this study was to examine the effect of the strains NZ86 (NRRL B-50136) and O14VRQ (NRRL B-67221) of B. subtilis on various parameters of the innate immunity in Nile tilapia (Oreochromis niloticus) in a 51-day feeding trial. Supplementation of tilapia with either strain resulted in significant increases (p < 0.05) in plasma lysozyme concentration of varying degrees throughout the trial. Meanwhile, alternative complement activity was significantly elevated (p < 0.05) only after feeding of the NZ86 strain after 14 and 51 days. Conversely, supplementation with O14VRQ resulted in a significant increase (p < 0.05) in the percent of neutrophils in the peripheral blood of tilapia by day 28. At the end of the trial, there was a trend towards increased phago...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2MURYKa
Publication date: Available online 23 August 2018Source: Fish & Shellfish ImmunologyAuthor(s): Cuiyun Zou, Xiaohong Tan, Huaqun Ye, Zhenzhu Sun, Shu Chen, Qingying Liu, Minglei Xu, Chaoxia Ye, Anli WangAbstractThe present study is aiming at evaluating the hepatoprotective of Radix Bupleuri extracts (RBE) on the d-galactosamine/lipopolysaccharide (D-GalN/LPS) induced liver injury of hybrid grouper in vitro and in vivo. In vitro, RBE (0, 200, 400 and 800 μg/ml) was added to the hybrid grouper primary hepatocytes before (pretreatment) the incubation of the hepatocytes with D-GalN (20 mM) plus LPS (1 μg/ml) in the culture medium. RBE at concentrations of 200, 400 and 800 μg/ml significantly improved cell viability and inhibited the elevation of TNF-α, IL-1β and IL-6 and significan...
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Publication date: Available online 31 August 2018Source: Fish & Shellfish ImmunologyAuthor(s): Wanying Jiao, Qi Han, Yanmin Xu, Huijie Jiang, Houjuan Xing, Xiaohua TengAbstractAs one of the mucosal lymphatic tissues, the gill is an important immune organ in fish. Water environmental pollutants enter fish body through the gill. Therefore, the gill is the initial site where pollutants produce toxic effects in water. Chlorpyrifos (CPF), broad-spectrum organophosphate insecticide, is widely used for agricultural pests and causes river pollution. In the present study, we investigated histopathological effect, oxidative stress indexes (SOD, GSH, T-AOC, and MDA), and apoptosis-related genes (P53, PUMA, Bax, Bcl-2, Apaf-1, Caspase-9, and Caspase-3) in the gills of common carp exposed to CPF. The r...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2oQQbao
Publication date: Available online 6 September 2018Source: Fish & Shellfish ImmunologyAuthor(s): Yeqing Lu, Hongkuan Zhang, Dewei Cheng, Hongxing Liu, Shengkang Li, Hongyu Ma, Huaiping ZhengAbstractC-type lectins have a variety of immunological functions in invertebrates. In order to investigate whether C-type lectin gene and carotenoids do have immune influences on noble scallop Chlamys nobilis under pathogen stress, acute challenges lasting 48 h to Vibrio parahaemolyticus, lipopolysaccharide (LPS), polyinosinic polycytidylic acid (Poly I: C), and PBS were conducted in noble scallop with different carotenoids content. A multi-CRD C-type lectin gene called Cnlec-1 was cloned and its transcripts under different challenges were determined. Full length cDNA of Cnlec-1 is 2267 bp with an ope...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2NYs9W2
Publication date: Available online 31 August 2018Source: Fish & Shellfish ImmunologyAuthor(s): Arokiadhas Iswarya, Baskaralingam Vaseeharan, Mahalingam Anjugam, Narayanan Gobi, Mani Divya, Caterina FaggioAbstractIn the present study, immunoenhancing effect of β-1, 3 glucan binding protein based selenium nanowire (Phβ-GBP-SeNWs) in common carp, Cyprinus carpio was assessed. Biological based selenium nanoform was synthesized, using crustacean immune molecule β-GBP purified from the haemolymph of Paratelphusa hydrodromus. The morphological property of Phβ-GBP-SeNWs was analyzed through TEM which reveals, the synthesized nanowire exhibits approximately 30–50 nm width with smooth surface. For this current study, fish were fed with experimental diet includes Phβ-GBP, sodium selenite, se...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2N1aJM7
Publication date: Available online 6 September 2018Source: Fish & Shellfish ImmunologyAuthor(s): Ryunkyoung Oh, Min Jeong Lee, Young-Ok Kim, Bo-Hye Nam, Hee Jeong Kong, Ju-Won Kim, Joong-yeon Park, Jung-Kil Seo, Dong-Gyun KimAbstractAn antimicrobial peptide with 55 amino acid residues was purified by C18 reversed-phase high-performance liquid chromatography (HPLC) from foot extract of the hard-shelled mussel, Mytilus coruscus. This peptide showed strong antimicrobial activity against Gram-positive and Gram-negative bacteria, as well as fungi.The purified peptide was determined to have a molecular mass of 6202 Da by matrix-assisted laser desorption/ionization time-of-flight mass spectrophotometry (MALDI-TOF/MS). The identified 20-amino acid sequence of the purified peak by Edman degradati...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2MbtpDE
Publication date: Available online 6 September 2018Source: Fish & Shellfish ImmunologyAuthor(s): Lingjie Luo, Juan Lu, Qin Wang, Shangwu Chen, Anlong Xu, Shaochun YuanAbstractAutophagy is a homeostatic process which degrades cytoplasmic constituents to maintain the balance of organs when they were challenged with nutrient stress. It also participates in cancer, neurodegenerative disorders, aging and innate immune defense. In order to reveal how autophagy participates in innate immune response when invertebrates evolved into vertebrates. Firstly, we performed a systematic analysis of Atg genes and found that they are highly conserved among lancelet, lamprey and zebrafish. Then, we observed autophagosomes upon starvation by TEM in lancelet, lamprey and zebrafish and found that the morphology...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2oSbdW4
In conclusion, we developed an efficient inactivated vaccine against V. harveyi in turbot, which not only induced humoral immunity, but also enhanced initial innate immune response for long-term protection. (Source: Fish and Shellfish Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2MbsV0i
This study was designed to gain a better understanding of the molecular mechanisms of apoptosis regulation in oyster hemocytes following exposure to P. marinus. Regulation of apoptosis-related genes in C. virginica, and apoptosis-regulatory genes in P. marinus, were investigated via qPCR to assess the possible pathways involved during these interactions. In vitro experiments were also carried out to evaluate the effect of chemical inhibitors of P. marinus antioxidant processes on hemocyte apoptosis. Results indicate the involvement of the mitochondrial pathway (Bcl-2, anamorsin) of apoptosis in C. virginica exposed to P. marinus. In parallel, the antioxidants peroxiredoxin and superoxide dismutase were regulated in P. marinus exposed to C. virginica hemocytes suggesting that apoptosis regu...
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
