Effect of red light and near infrared laser on the generation of reactive oxygen species in primary dermal fibroblasts

Publication date: Available online 6 September 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Sajan George, Michael R. Hamblin, Heidi AbrahamseAbstractIrradiation with red light or near-infrared (NIR) lasers can bio-modulate cellular processes or revitalize injured tissues and therefore, widely been used for therapeutic interventions. Mechanistically, this cellular or biological process, referred as Photobiomodulation (PBM), is achieved by the generation of oxide free radicals in cells and tissues. This explorative study using red light (636 nm) and Near Infra-Red (NIR, 825 nm) laser at various irradiation exposures reckons the level of oxidative stress induced by these free radicals in human primary fibroblasts. Freshly isolated dermal fibroblasts were irr...

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