Cytokine profiles in cerebrospinal fluid of patients with meningitis at a tertiary general hospital in China

ConclusionsThe excessive activation of immune response characterized by elevated levels of CSF Th1-, Th2- and Th17-type cytokines has been observed during CNS infection. Furthermore, we observed negative correlations between CSF IL-6 levels and CSF glucose and CSF/blood glucose ratio in CNS infection. And we suggested that combined CSF IL-6 levels with CSF glucose may serve as a novel biomarker pool for the differential of CNS infection. (Source: Journal of Microbiology, Immunology and Infection)

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