Σάββατο 3 Νοεμβρίου 2018

Fungal vaccines, mechanism of actions and immunology: A comprehensive review

Publication date: January 2019Source: Biomedicine & Pharmacotherapy, Volume 109Author(s): Sanam Nami, Rasoul Mohammadi, Mahshid Vakili, Kimia Khezripour, Hamed Mirzaei, Hamid MorovatiAbstractFungal infections include a wide range of opportunistic and invasive diseases. Two of four major fatal diseases in patients with human immunodeficiency virus (HIV) infection are related to the fungal infections, cryptococcosis, and pneumocystosis. Disseminated candidiasis and different clinical forms of aspergillosis annually impose expensive medical costs to governments and hospitalized patients and ultimately lead to high mortality rates. Therefore, urgent implementations are necessary to prevent the expansion of these diseases. Designing an effective vaccine is one of the most important approaches i...

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