Σάββατο 6 Οκτωβρίου 2018

Expression profiling and functional characterization of galectin-3 of turbot (Scophthalmus maximus L.) in host mucosal immunity

Publication date: Available online 6 October 2018Source: Fish & Shellfish ImmunologyAuthor(s): Mengyu Tian, Ning Yang, Lu Zhang, Qiang Fu, Fenghua Tan, Chao LiAbstractGalectins, a family of evolutionary conserved β-galactoside-binding proteins, have been characterized in wide range of species. Galectin-3 is the only member in the chimera type, which is monomeric lectin with one CRD domain. A growing body of evidence have indicated vital roles of galectin-3 in innate immune responses against infection. Here, one galectin-3 gene was captured in turbot (SmLgals3) contains a 1203 bp open reading frame (ORF). In comparison to other species, SmLgals3 showed the highest similarity and identity to large yellow croaker and medaka, respectively. The genomic structure analysis showed that SmLgals3 h...

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