Surface treatment with non-thermal humid argon plasma as a treatment for allergic contact dermatitis in a mouse model

Publication date: December 2018Source: Clinical Plasma Medicine, Volume 12Author(s): Qing Xiong, Xia Wang, Rui Yin, Lin Xiong, Qiang Chen, Meng-Xue Zheng, Le Xu, Qing-Hua Huang, Michael R HamblinAbstractCold plasma generated at atmospheric pressure has attracted intense interest in biomedical applications, particularly as an antimicrobial treatment. Here we report the therapeutic effect of humidified cold argon plasma on allergic contact dermatitis (ACD) in a mouse model. Treatment was carried out with different gas compositions: argon gas containing small amounts of either N2, O2, or H2O. The best effect was obtained using humid plasma (H2O addition), where the ACD symptoms decreased after one or two 1-min plasma treatments. Even for severe ACD with ulcers and crust formation, the humid p...

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