House Dust Mite Tablets Now Officially Accepted as Treatment in GINA: What Is the Evidence and What ’s Next?

AbstractPurpose of ReviewThis review analyzes the growing evidence regarding the standardized quality house dust mite (SQ-HDM) sublingual immunotherapy (SLIT) tablets as a valuable therapeutic option in asthma, as recently included in the treatment algorithm of the Global Initiative for Asthma (GINA) as an add-on treatment for adult patients with allergic asthma not well controlled with inhaled corticosteroids (ICS).Recent FindingsEvidence from well-designed randomized placebo-controlled clinical trials shows that the SQ-HDM SLIT tablet is effective vs. placebo in reducing both asthma symptoms and the need for ICS, as well as the risk of experiencing a moderate/severe asthma exacerbation following ICS reduction, besides having a very good safety profile and tolerability. However, some unme...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RiPwe4