Biogenic Au@ZnO core –shell nanocomposites kill Staphylococcus aureus without provoking nuclear damage and cytotoxicity in mouse fibroblasts cells under hyperglycemic condition with enhanced wound healing proficiency

AbstractThe aim of the present study is focused on the synthesis of Au@ZnO core –shell nanocomposites, where zinc oxide is overlaid on biogenic gold nanoparticles obtained fromHibiscus Sabdariffa plant extract. Optical property of nanocomposites is investigated using UV –visible spectroscopy and crystal structure has been determined using X-ray crystallography (XRD) technique. The presence of functional groups on the surface of Au@ZnO core–shell nanocomposites has been observed by Fourier transforms infrared (FTIR) spectroscopy. Electron microscopy studies reve aled the morphology of the above core–shell nanocomposites. The synthesized nanocomposite material has shown antimicrobial and anti-biofilm activity againstStaphylococcus aureus and Methicillin ResistantStaphylococcus haemol...

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