Contrast-enhanced ultrasound in delayed splenic vascular injury and active extravasation diagnosis

Abstract

Introduction

We describe the use of contrast-enhanced ultrasound (CEUS) in the diagnosis of delayed splenic vascular injury (DSVI) and active extravasation (DAE) during spleen injury follow-up. CEUS might be used instead of contrast-enhanced computed tomography (CECT) during spleen injury follow-up in order to reduce radiation exposure.

Objective

Assess diagnostic comparability between CEUS and CECT in the evaluation of DSVI and DAE during spleen injury follow-up.

Subjects and methods

A total of 139 trauma patients (101 males, 38 females; mean age 48.6 years) with CECT diagnosed spleen injury were prospectively evaluated. They performed CEUS and CECT follow-up. All CEUS studies were performed using the same ultrasound scan, convex probe, mechanical index and ultrasound contrast agent dose. Twelve patients performed digital subtraction angiography (DSA) during follow-up, and the diagnostic performance comparability between CEUS and DSA was evaluated.

Results

CEUS showed 17 delayed spleen injury complications, and in 122 patients no complication was suspected. CECT diagnosed 16 delayed spleen injury complications in these 17 patients and showed a small DSVI in another patient. A total of 122 follow-up CT scans were negative. CEUS and CECT diagnostic comparability was 98.6%. Compared to DSA, CEUS showed a sensitivity of 100% and a positive predictive value of 91.7%.

Conclusions

CEUS can be used during spleen injury follow-up instead of CECT. Positive CEUS examinations could perform CECT and, when necessary, DSA in order to confirm and treat spleen injury complications.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zujLZ3

Change in endolymphatic hydrops 2 years after endolymphatic sac surgery evaluated by MRI

This study was performed to determine whether endolymphatic sac surgery improves vestibular and cochlear endolymphatic hydrops 2 years after sac surgery and to elucidate the relationship between the degree of improvement of endolymphatic hydrops and the changes in vertigo symptoms, the hearing level, and the summating potential/action potential ratio ( −SP/AP ratio) by electrocochleography (ECochG) in patients with Ménière's disease (MD). (Source: Auris, Nasus, Larynx)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5OBfK

Fluorescence imaging of invasive head and neck carcinoma cells with integrin αvβ6-targeting RGD-peptides: an approach to a fluorescence-assisted intraoperative cytological assessment of bony resection margins

We assessed the use of peptides containing arginylglycylaspartic acid (RGD) that target integrin αvβ6 as a potential approach for a fluorescence-assisted intraoperative cytological assessment of bony resection margins (F-AICAB) in patients who had bone-infiltrating squamous cell carcinoma (SCC) of the head and neck. This was assessed to demarcate invasive carcinoma cells that stained for αvβ 6. Specimens from bony resection margins (n=362) were defined as either malignant or benign according to the results of cytological and histological examinations. (Source: The British Journal of Oral and Maxillofacial Surgery)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Q10FUI

Fluorescence imaging of invasive head and neck carcinoma cells with integrin αvβ6-targeting RGD-peptides: an approach to a fluorescence-assisted intraoperative cytological assessment of bony resection margins

We assessed the use of peptides containing arginylglycylaspartic acid (RGD) that target integrin αvβ6 as a potential approach for a fluorescence-assisted intraoperative cytological assessment of bony resection margins (F-AICAB) in patients who had bone-infiltrating squamous cell carcinoma (SCC) of the head and neck. This was assessed to demarcate invasive carcinoma cells that stained for αvβ 6. Specimens from bony resection margins (n=362) were defined as either malignant or benign according to the results of cytological and histological examinations. (Source: The British Journal of Oral and Maxillofacial Surgery)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Q10FUI

Laundry detergents and detergent residue after rinse directly disrupt tight junction barrier integrity in human bronchial epithelial cells

Laundry detergents and rinse residue at high dilutions show a directly disruptive effect on tight junction barrier integrity of bronchial epithelial cells, suggesting a mechanism for increased penetration of pathogens, allergens and irritants through mucosa. (Source: Journal of Allergy and Clinical Immunology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DLs3yC

The Microbiome in Atopic Dermatitis

As an interface with the environment, the skin is a complex ecosystem, colonized by many microorganisms that coexist in an established balance. The cutaneous microbiome inhibits colonization with pathogens such as S. aureus and is a crucial component for function of the epidermal barrier. Moreover, crosstalk between commensals and the immune system is now recognized, as microorganisms can modulate innate, as well as adaptive, immune responses. Host-commensal interactions also have an impact on the developing immune system in infants and subsequently the occurrence of diseases such as asthma and atopic dermatitis. (Source: Journal of Allergy and Clinical Immunology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QlbbFU

Laundry detergents and detergent residue after rinse directly disrupt tight junction barrier integrity in human bronchial epithelial cells

Laundry detergents and rinse residue at high dilutions show a directly disruptive effect on tight junction barrier integrity of bronchial epithelial cells, suggesting a mechanism for increased penetration of pathogens, allergens and irritants through mucosa. (Source: Journal of Allergy and Clinical Immunology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DLs3yC

The Microbiome in Atopic Dermatitis

As an interface with the environment, the skin is a complex ecosystem, colonized by many microorganisms that coexist in an established balance. The cutaneous microbiome inhibits colonization with pathogens such as S. aureus and is a crucial component for function of the epidermal barrier. Moreover, crosstalk between commensals and the immune system is now recognized, as microorganisms can modulate innate, as well as adaptive, immune responses. Host-commensal interactions also have an impact on the developing immune system in infants and subsequently the occurrence of diseases such as asthma and atopic dermatitis. (Source: Journal of Allergy and Clinical Immunology)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QlbbFU

Novel compound heterozygous mutations in SLC26A4 gene in a Chinese family with enlarged vestibular aqueduct.

This study demonstrates that the novel frameshift mutation c.574delC (p.Leu192Ter) in compound heterozygosity with c.919-2A>G in the SLC26A4 gene is the main cause of deafness in a family. Our study will expand the spectrum of known SLC26A4 mutations in the Chinese population, providing more information on genetic counseling, and diagnosis in hearing loss with EVA. PMID: 30473558 [PubMed - in process] (Source: BioScience Trends)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TSbKWn

A novel compound heterozygous mutation in the GJB2 gene is associated with non-syndromic hearing loss in a Chinese family.

Authors: Jiang H, Niu Y, Qu L, Huang X, Zhu X, Tang G Abstract Autosomal recessive (AR) non-syndromic hearing loss (NSHL) is the most common form of hereditary deafness. Mutations in the gap junction protein beta 2 (GJB2) gene encoding connexin 26 (Cx26) account for about 50% of cases of ARNSHL. In the current study, a combination of exome sequencing and Sanger sequencing in a Chinese Dong family with ARNSHL allowed identification of a novel compound heterozygous mutation c.240G>C(p. Q80H)/C.109G>A(p.V37I) in exon 2 of the GJB2 gene, which co-segregated with the disease phenotype in this family and was not evident in 100 healthy controls. Bioinformatic analysis revealed that the two mutations in the GJB2 gene were probably pathogenic. Results indicated that the compound heter...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AwV8un

Associated tympanic bullar and cochlear hypertrophy define adaptations to true deserts in African gerbils and laminate-toothed rats (Muridae: Gerbillinae and Murinae).

This study concludes that in both arid and semi-arid adapted laminate-toothed rats and gerbils there is bulla and associated cochlea hypertrophy, particularly in true desert species. Gerbils also show tightly coiled cochlea but the significance of this is debatable and may have nothing to do with adaptations to any specific acoustics in the desert environment. PMID: 30474264 [PubMed - as supplied by publisher] (Source: Journal of Anatomy)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPi40O

Novel compound heterozygous mutations in SLC26A4 gene in a Chinese family with enlarged vestibular aqueduct.

This study demonstrates that the novel frameshift mutation c.574delC (p.Leu192Ter) in compound heterozygosity with c.919-2A>G in the SLC26A4 gene is the main cause of deafness in a family. Our study will expand the spectrum of known SLC26A4 mutations in the Chinese population, providing more information on genetic counseling, and diagnosis in hearing loss with EVA. PMID: 30473558 [PubMed - in process] (Source: BioScience Trends)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TSbKWn

A novel compound heterozygous mutation in the GJB2 gene is associated with non-syndromic hearing loss in a Chinese family.

Authors: Jiang H, Niu Y, Qu L, Huang X, Zhu X, Tang G Abstract Autosomal recessive (AR) non-syndromic hearing loss (NSHL) is the most common form of hereditary deafness. Mutations in the gap junction protein beta 2 (GJB2) gene encoding connexin 26 (Cx26) account for about 50% of cases of ARNSHL. In the current study, a combination of exome sequencing and Sanger sequencing in a Chinese Dong family with ARNSHL allowed identification of a novel compound heterozygous mutation c.240G>C(p. Q80H)/C.109G>A(p.V37I) in exon 2 of the GJB2 gene, which co-segregated with the disease phenotype in this family and was not evident in 100 healthy controls. Bioinformatic analysis revealed that the two mutations in the GJB2 gene were probably pathogenic. Results indicated that the compound heter...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AwV8un

Associated tympanic bullar and cochlear hypertrophy define adaptations to true deserts in African gerbils and laminate-toothed rats (Muridae: Gerbillinae and Murinae).

This study concludes that in both arid and semi-arid adapted laminate-toothed rats and gerbils there is bulla and associated cochlea hypertrophy, particularly in true desert species. Gerbils also show tightly coiled cochlea but the significance of this is debatable and may have nothing to do with adaptations to any specific acoustics in the desert environment. PMID: 30474264 [PubMed - as supplied by publisher] (Source: Journal of Anatomy)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPi40O

Zapping the Olfactory Bulb Produces Phantom Smells

Researchers envision a cochlear implant–like device for the nose to give people with impaired olfaction a sense of smell. (Source: The Scientist)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Q0F66C

Zapping the Olfactory Bulb Produces Phantom Smells

Researchers envision a cochlear implant–like device for the nose to give people with impaired olfaction a sense of smell. (Source: The Scientist)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Q0F66C

DNN-based performance measures for predicting error rates in automatic speech recognition and optimizing hearing aid parameters

In this study, we look at different performance measures to estimate the word error rates of simulated behind-the-ear hearing aid signals and detect the azimuth angle of the target source in 180-degree spatial scenes. These measures derive from phoneme posterior probabilities produced by a deep neural network acoustic model. However, the more complex the model is, the more computationally expensive it becomes to obtain these measures; therefore, we assess how the model size affects prediction performance. Our findings suggest smaller nets are suitable to predict error rates of more complex models reliably enough to be implemented in hearing aid hardware. (Source: Speech Communication)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PZjmbz

Tonotopy in calcium homeostasis and vulnerability of cochlear hair cells.

Authors: Fettiplace R, Nam JH Abstract Ototoxicity, noise overstimulation, or aging, can all produce hearing loss with similar properties, in which outer hair cells (OHCs), principally those at the high-frequency base of the cochlea, are preferentially affected. We suggest that the differential vulnerability may partly arise from differences in Ca2+ balance among cochlear locations. Homeostasis is determined by three factors: Ca2+ influx mainly via mechanotransducer (MET) channels; buffering by calcium-binding proteins and organelles like mitochondria; and extrusion by the plasma membrane CaATPase pump. We review quantification of these parameters and use our experimentally-determined values to model changes in cytoplasmic and mitochondrial Ca2+ during Ca2+ influx through the MET c...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BCannH

DNN-based performance measures for predicting error rates in automatic speech recognition and optimizing hearing aid parameters

In this study, we look at different performance measures to estimate the word error rates of simulated behind-the-ear hearing aid signals and detect the azimuth angle of the target source in 180-degree spatial scenes. These measures derive from phoneme posterior probabilities produced by a deep neural network acoustic model. However, the more complex the model is, the more computationally expensive it becomes to obtain these measures; therefore, we assess how the model size affects prediction performance. Our findings suggest smaller nets are suitable to predict error rates of more complex models reliably enough to be implemented in hearing aid hardware. (Source: Speech Communication)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PZjmbz

Tonotopy in calcium homeostasis and vulnerability of cochlear hair cells.

Authors: Fettiplace R, Nam JH Abstract Ototoxicity, noise overstimulation, or aging, can all produce hearing loss with similar properties, in which outer hair cells (OHCs), principally those at the high-frequency base of the cochlea, are preferentially affected. We suggest that the differential vulnerability may partly arise from differences in Ca2+ balance among cochlear locations. Homeostasis is determined by three factors: Ca2+ influx mainly via mechanotransducer (MET) channels; buffering by calcium-binding proteins and organelles like mitochondria; and extrusion by the plasma membrane CaATPase pump. We review quantification of these parameters and use our experimentally-determined values to model changes in cytoplasmic and mitochondrial Ca2+ during Ca2+ influx through the MET c...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BCannH

Zapping the Olfactory Bulb Produces Phantom Smells

Researchers envision a cochlear implant–like device for the nose to give people with impaired olfaction a sense of smell. (Source: The Scientist)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Q0F66C

Zapping the Olfactory Bulb Produces Phantom Smells

Researchers envision a cochlear implant–like device for the nose to give people with impaired olfaction a sense of smell. (Source: The Scientist)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Q0F66C

An age-based analysis of nonmedical prescription opioid use among people who use illegal drugs in Vancouver, Canada

Nonmedical prescription opioid use (NMPOU) is a serious public health problem in North America. At a population-level, previous research has identified differences in the prevalence and correlates of NMPOU amo...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ArGeWt

Residual bone fragments in tibiofibular joint and postoperative local recurrence: an analysis of 21 cases of proximal fibular giant cell tumour

Currently, there are no known reports on the aetiology of local giant cell tumour (GCT) recurrence in the proximal fibula following en bloc resection. We analysed 21 cases of proximal fibular GCT, focusing on ...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FLUbnV

An age-based analysis of nonmedical prescription opioid use among people who use illegal drugs in Vancouver, Canada

Nonmedical prescription opioid use (NMPOU) is a serious public health problem in North America. At a population-level, previous research has identified differences in the prevalence and correlates of NMPOU amo...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ArGeWt

Residual bone fragments in tibiofibular joint and postoperative local recurrence: an analysis of 21 cases of proximal fibular giant cell tumour

Currently, there are no known reports on the aetiology of local giant cell tumour (GCT) recurrence in the proximal fibula following en bloc resection. We analysed 21 cases of proximal fibular GCT, focusing on ...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FLUbnV

Editorial Board

Publication date: December 2018Source: Speech Communication, Volume 105Author(s): (Source: Speech Communication)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RjrAb5

DNN-based performance measures for predicting error rates in automatic speech recognition and optimizing hearing aid parameters

In this study, we look at different performance measures to estimate the word error rates of simulated behind-the-ear hearing aid signals and detect the azimuth angle of the target source in 180-degree spatial scenes. These measures derive from phoneme posterior probabilities produced by a deep neural network acoustic model. However, the more complex the model is, the more computationally expensive it becomes to obtain these measures; therefore, we assess how the model size affects prediction performance. Our findings suggest smaller nets are suitable to predict error rates of more complex models reliably enough to be implemented in hearing aid hardware. (Source: Speech Communication)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PZjmbz

An Iterative Mask Estimation Approach to Deep Learning Based Multi-Channel Speech Recognition

Publication date: Available online 26 November 2018Source: Speech CommunicationAuthor(s): Yan-Hui Tu, Jun Du, Lei Sun, Feng Ma, Hai-Kun Wang, Jing-Dong Chen, Chin-Hui LeeAbstractWe propose a novel iterative mask estimation (IME) framework to improve the state-of-the-art complex Gaussian mixture model (CGMM)-based beamforming approach in an iterative manner by leveraging upon the complementary information obtained from different deep models. Although CGMM has been recently demonstrated to be quite effective for multi-channel, automation speech recognition (ASR) in operational scenarios, the corresponding mask estimation, however, is not always accurate in adverse environments due to the lack of prior or context information. To address this problem, in this study, a neural-network-based idea...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RhNGKR

Introduction

Publication date: Available online 26 November 2018Source: LinguaAuthor(s): Shi Feng (Source: Lingua)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PZjeJ7

Adults with Communication Disabilities Experience Poorer Health and Healthcare Outcomes Compared to Persons Without Communication Disabilities

ConclusionsPersons with CD are medically complex and experience greater challenges accessing healthcare than persons without CD. Healthcare providers need support and tools to provide equitable care that addresses the medical needs of persons with CD. (Source: Journal of General Internal Medicine)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RigqmU

Editorial Board

Publication date: December 2018Source: Speech Communication, Volume 105Author(s): (Source: Speech Communication)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RjrAb5

An Iterative Mask Estimation Approach to Deep Learning Based Multi-Channel Speech Recognition

Publication date: Available online 26 November 2018Source: Speech CommunicationAuthor(s): Yan-Hui Tu, Jun Du, Lei Sun, Feng Ma, Hai-Kun Wang, Jing-Dong Chen, Chin-Hui LeeAbstractWe propose a novel iterative mask estimation (IME) framework to improve the state-of-the-art complex Gaussian mixture model (CGMM)-based beamforming approach in an iterative manner by leveraging upon the complementary information obtained from different deep models. Although CGMM has been recently demonstrated to be quite effective for multi-channel, automation speech recognition (ASR) in operational scenarios, the corresponding mask estimation, however, is not always accurate in adverse environments due to the lack of prior or context information. To address this problem, in this study, a neural-network-based idea...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RhNGKR

Introduction

Publication date: Available online 26 November 2018Source: LinguaAuthor(s): Shi Feng (Source: Lingua)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PZjeJ7

Adults with Communication Disabilities Experience Poorer Health and Healthcare Outcomes Compared to Persons Without Communication Disabilities

ConclusionsPersons with CD are medically complex and experience greater challenges accessing healthcare than persons without CD. Healthcare providers need support and tools to provide equitable care that addresses the medical needs of persons with CD. (Source: Journal of General Internal Medicine)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RigqmU

Recovernow: A Multicentre Of Tablet-Based Speech Therapy For Post-Stroke Aphasia

Condition:   Stroke Sequelae Interventions:   Other: Speech therapy apps;   Other: Non-speech therapy apps Sponsor:   Ottawa Hospital Research Institute Not yet recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DP1Bo4

Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome

Conditions:   Sleep Apnea, Obstructive;   Hypertension Secondary Interventions:   Other: Speech therapy;   Other: Control Sponsor:   Universidade Federal do Rio de Janeiro Active, not recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ql7906

Recovernow: A Multicentre Of Tablet-Based Speech Therapy For Post-Stroke Aphasia

Condition:   Stroke Sequelae Interventions:   Other: Speech therapy apps;   Other: Non-speech therapy apps Sponsor:   Ottawa Hospital Research Institute Not yet recruiting (Source: ClinicalTrials.gov)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DP1Bo4

Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome

Conditions:   Sleep Apnea, Obstructive;   Hypertension Secondary Interventions:   Other: Speech therapy;   Other: Control Sponsor:   Universidade Federal do Rio de Janeiro Active, not recruiting (Source: ClinicalTrials.gov)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ql7906

Music supports the auditory skills of hearing-impaired children

(University of Helsinki) Researchers at University of Helsinki, Finland, and University College London have found evidence that children with hearing impairment and cochlear implants can benefit from hobbies involving music and especially singing. (Source: EurekAlert! - Social and Behavioral Science)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r84NmZ

Music supports the auditory skills of hearing-impaired children

(University of Helsinki) Researchers at University of Helsinki, Finland, and University College London have found evidence that children with hearing impairment and cochlear implants can benefit from hobbies involving music and especially singing. (Source: EurekAlert! - Social and Behavioral Science)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r84NmZ

Omalizumab discontinuation in children with severe allergic asthma: an observational real life study

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AsUpuh

Omalizumab discontinuation in children with severe allergic asthma: an observational real life study

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AsUpuh

Music supports the auditory skills of hearing-impaired children

(University of Helsinki) Researchers at University of Helsinki, Finland, and University College London have found evidence that children with hearing impairment and cochlear implants can benefit from hobbies involving music and especially singing. (Source: EurekAlert! - Social and Behavioral Science)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r84NmZ

Fat Grafting in Composite Breast Augmentation with Round Implants: A New Concept for Breast Reshaping

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AuXXMR

Photobiomodulation Improved the First Stages of Wound Healing Process After Abdominoplasty: An Experimental, Double-Blinded, Non-randomized Clinical Trial

Abstract

Background

Photobiomodulation is widely studied for its potential benefits in the wound healing process. Numerous scientific studies have highlighted its effect on various phases of wound repair, but clinical validations are few. This comparative trial aims to evaluate the influence of photobiomodulation on the post-abdominoplasty healing process.

Methods

Seventeen Caucasian women (aged 18–55) who underwent an abdominoplasty were enrolled in this double-blinded, controlled clinical trial. The postoperative scars were divided into two areas; the right side of the scars was treated with ten sessions of photobiomodulation (consisting in three types of wavelengths). The other part of the scars was used as control and did not receive any additional treatment. Clinical assessments of both parts of the scars were scheduled at 1, 6 and 12 months postoperative.

Results

Within six months following surgery, significantly improved quality of the scars on the treated side compared with the untreated side was reported by patients and experienced professionals according to Vancouver Scar Scale, Patient and Observer Scar Assessment Scale (p < 0.05) and standardized photographs (p < 0.05). At 1 year of follow-up, patients observed no differences between the treated and untreated sides of the scars. This suggests that photobiomodulation appears to play an early role in the wound healing process, accelerating the first stages of cicatrization.

Conclusion

This study statistically validates the positive impact of photobiomodulation treatment on the first stages of the postoperative healing process. Carried out on Caucasians participants only, this study should, however, be performed on a more heterogeneous population to definitively confirm these effects on an international population.

Clinical trial registry

Registro Brasileiro de ensaios clínicos: http://www.ensaiosclinicos.gov.br, Trial RBR-49PK78.

Level of Evidence II

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPajIp

Secondary Breast Augmentation: Is there a Trend for Bigger Implants?

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TWniYW

Levator Pull-Out Suture Technique for Immediate Postoperative Correction of Eyelid Asymmetry After Ptosis Surgery in Asians

Abstract

Background

Postoperative eyelid asymmetry is the most common complaint of patients after undergoing blepharoplasty and ptosis correction surgery. Calibrating eyelid asymmetry during ptosis correction surgery is still difficult for surgeons despite the development of innovative procedures. Our levator pull-out suture technique for correcting postoperative eyelid asymmetry after ptosis surgery is introduced.

Methods

A total of 330 patients who underwent ptosis correction surgery with upper blepharoplasty from 2016 to 2017 were enrolled in our study. All surgeries were performed using the levator pull-out suture technique, and the postoperative eyelid asymmetry was corrected in the outpatient clinic at 2–3 days after the operation. Patient satisfaction was evaluated preoperatively and at 1 week and 2 months postoperatively using a questionnaire. Visual acuity, marginal reflex distance 1 (MRD1), and vertical palpebral fissure length asymmetry were measured preoperatively and compared to values taken postoperatively.

Results

Patient satisfaction regarding asymmetry increased from 2.7/5 (preoperatively) to 4.1/5 points (postoperatively). MRD1 and vertical palpebral fissure length increased from 1.1/1.2 and 6.8/6.8 mm (preoperatively), respectively, to 2.8/2.9 and 8.5/8.6 mm (postoperatively), respectively. The asymmetry of MRD1 and vertical palpebral fissure length before and after surgery were corrected from 0.45/1.81 to 0.01/0.19 mm (p < 0.01).

Conclusion

Our innovative surgical method of using the levator pull-out suture technique is relatively simple and allows for finer suture adjustments postoperatively to effectively correct eyelid asymmetry, with satisfactory results.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ay2Y74

Music supports the auditory skills of hearing-impaired children

(University of Helsinki) Researchers at University of Helsinki, Finland, and University College London have found evidence that children with hearing impairment and cochlear implants can benefit from hobbies involving music and especially singing. (Source: EurekAlert! - Social and Behavioral Science)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r84NmZ

Fat Grafting in Composite Breast Augmentation with Round Implants: A New Concept for Breast Reshaping

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AuXXMR

Photobiomodulation Improved the First Stages of Wound Healing Process After Abdominoplasty: An Experimental, Double-Blinded, Non-randomized Clinical Trial

Abstract

Background

Photobiomodulation is widely studied for its potential benefits in the wound healing process. Numerous scientific studies have highlighted its effect on various phases of wound repair, but clinical validations are few. This comparative trial aims to evaluate the influence of photobiomodulation on the post-abdominoplasty healing process.

Methods

Seventeen Caucasian women (aged 18–55) who underwent an abdominoplasty were enrolled in this double-blinded, controlled clinical trial. The postoperative scars were divided into two areas; the right side of the scars was treated with ten sessions of photobiomodulation (consisting in three types of wavelengths). The other part of the scars was used as control and did not receive any additional treatment. Clinical assessments of both parts of the scars were scheduled at 1, 6 and 12 months postoperative.

Results

Within six months following surgery, significantly improved quality of the scars on the treated side compared with the untreated side was reported by patients and experienced professionals according to Vancouver Scar Scale, Patient and Observer Scar Assessment Scale (p < 0.05) and standardized photographs (p < 0.05). At 1 year of follow-up, patients observed no differences between the treated and untreated sides of the scars. This suggests that photobiomodulation appears to play an early role in the wound healing process, accelerating the first stages of cicatrization.

Conclusion

This study statistically validates the positive impact of photobiomodulation treatment on the first stages of the postoperative healing process. Carried out on Caucasians participants only, this study should, however, be performed on a more heterogeneous population to definitively confirm these effects on an international population.

Clinical trial registry

Registro Brasileiro de ensaios clínicos: http://www.ensaiosclinicos.gov.br, Trial RBR-49PK78.

Level of Evidence II

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPajIp

Secondary Breast Augmentation: Is there a Trend for Bigger Implants?

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TWniYW

Levator Pull-Out Suture Technique for Immediate Postoperative Correction of Eyelid Asymmetry After Ptosis Surgery in Asians

Abstract

Background

Postoperative eyelid asymmetry is the most common complaint of patients after undergoing blepharoplasty and ptosis correction surgery. Calibrating eyelid asymmetry during ptosis correction surgery is still difficult for surgeons despite the development of innovative procedures. Our levator pull-out suture technique for correcting postoperative eyelid asymmetry after ptosis surgery is introduced.

Methods

A total of 330 patients who underwent ptosis correction surgery with upper blepharoplasty from 2016 to 2017 were enrolled in our study. All surgeries were performed using the levator pull-out suture technique, and the postoperative eyelid asymmetry was corrected in the outpatient clinic at 2–3 days after the operation. Patient satisfaction was evaluated preoperatively and at 1 week and 2 months postoperatively using a questionnaire. Visual acuity, marginal reflex distance 1 (MRD1), and vertical palpebral fissure length asymmetry were measured preoperatively and compared to values taken postoperatively.

Results

Patient satisfaction regarding asymmetry increased from 2.7/5 (preoperatively) to 4.1/5 points (postoperatively). MRD1 and vertical palpebral fissure length increased from 1.1/1.2 and 6.8/6.8 mm (preoperatively), respectively, to 2.8/2.9 and 8.5/8.6 mm (postoperatively), respectively. The asymmetry of MRD1 and vertical palpebral fissure length before and after surgery were corrected from 0.45/1.81 to 0.01/0.19 mm (p < 0.01).

Conclusion

Our innovative surgical method of using the levator pull-out suture technique is relatively simple and allows for finer suture adjustments postoperatively to effectively correct eyelid asymmetry, with satisfactory results.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ay2Y74

Fat Grafting in Composite Breast Augmentation with Round Implants: A New Concept for Breast Reshaping

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2AuXXMR

Secondary Breast Augmentation: Is there a Trend for Bigger Implants?

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TWniYW

Levator Pull-Out Suture Technique for Immediate Postoperative Correction of Eyelid Asymmetry After Ptosis Surgery in Asians

Abstract

Background

Postoperative eyelid asymmetry is the most common complaint of patients after undergoing blepharoplasty and ptosis correction surgery. Calibrating eyelid asymmetry during ptosis correction surgery is still difficult for surgeons despite the development of innovative procedures. Our levator pull-out suture technique for correcting postoperative eyelid asymmetry after ptosis surgery is introduced.

Methods

A total of 330 patients who underwent ptosis correction surgery with upper blepharoplasty from 2016 to 2017 were enrolled in our study. All surgeries were performed using the levator pull-out suture technique, and the postoperative eyelid asymmetry was corrected in the outpatient clinic at 2–3 days after the operation. Patient satisfaction was evaluated preoperatively and at 1 week and 2 months postoperatively using a questionnaire. Visual acuity, marginal reflex distance 1 (MRD1), and vertical palpebral fissure length asymmetry were measured preoperatively and compared to values taken postoperatively.

Results

Patient satisfaction regarding asymmetry increased from 2.7/5 (preoperatively) to 4.1/5 points (postoperatively). MRD1 and vertical palpebral fissure length increased from 1.1/1.2 and 6.8/6.8 mm (preoperatively), respectively, to 2.8/2.9 and 8.5/8.6 mm (postoperatively), respectively. The asymmetry of MRD1 and vertical palpebral fissure length before and after surgery were corrected from 0.45/1.81 to 0.01/0.19 mm (p < 0.01).

Conclusion

Our innovative surgical method of using the levator pull-out suture technique is relatively simple and allows for finer suture adjustments postoperatively to effectively correct eyelid asymmetry, with satisfactory results.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ay2Y74

The perioperative patient on buprenorphine: a systematic review of perioperative management strategies and patient outcomes

Abstract

Background

An increasing number of patients with opioid use disorder (OUD) are treated with opioid agonist-antagonists such as buprenorphine/naloxone. Perioperative management of patients on buprenorphine/naloxone is inconsistent and remains a controversial topic with mismanagement posing a significant risk to the long-term health of these patients.

Methods

We performed a systematic literature search involving Medline, Medline In-Process, Embase, Cochrane Central, Cochrane Database of Systematic Reviews, PsycINFO, Web of Science (Clarivate), Scopus (Elsevier), CINAHL (EbscoHosst), and PubMed (NLM).

Results

Eighteen studies were included in the final sample, including one controlled study and four observational studies . Neither the controlled study nor the observational studies assessed addiction treatment retention, harm reduction, or long-term mortality rates as primary or secondary outcomes. Of the observational studies, authors showed equivalent peri- and postoperative pain control among buprenorphine continued patients. All but one authors described adequate analgesia among the case reports in which buprenorphine ≤ 16 mg sublingually (SL) daily was continued during the perioperative period. Long-term harm reduction was not reported with only three case reports including any long-term abstinence or relapse rates.

Conclusions

The current understanding of the risks and benefits of continuing or stopping buprenorphine perioperatively is limited by a lack of high-quality evidence. Observational studies and case reports indicate no evidence against continuing buprenorphine perioperatively, especially when the dose is < 16 mg SL daily. In patients with significant potential for relapse, such as those with a recent history of OUD, the discontinuation of buprenorphine should have a strong rationale supported by patient and surgical preferences. Future studies require standardized reporting of median doses, details on the route of delivery, dosing schedules and any dosing changes, and rates of addiction relapse, including long-term morbidity and mortality where possible.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r814pv

Évaluation de l’impact du projet Lifebox au Burkina Faso sur la pratique de l’oxymétrie pulsée et la check-list de l’organisation mondiale de la santé pour la sécurité du patient au bloc opératoire

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FH9GgP

The need to collect, aggregate, and analyze global anesthesia and surgery data

Abstract

In the Sustainable Development Goals era, there is a new awareness of the need for an integrated approach to healthcare interventions and a strong commitment to Universal Health Coverage. To achieve the goal of strengthening entire health systems, surgery, as a crosscutting treatment modality, is indispensable. For any health system strengthening exercise, baseline data and longitudinal monitoring of progress are necessary. With improved data capabilities, there are unparalleled possibilities to map out and understand systems, integrating data from many sources and sectors. Nevertheless, there is also a need to prioritize among indicators to avoid information overload and data collection fatigue. There is a similar need to define indicators and collection methodology to create standardized and comparable data. Finally, there is a need to establish data pathways to ensure clear responsibilities amongst national and international institutions and integrate surgical metrics into existing mechanisms for sustainable data collection. This is a call to collect, aggregate, and analyze global anesthesia and surgery data, with an account of existing data sources and a proposed way forward.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r812hn

Photobiomodulation Improved the First Stages of Wound Healing Process After Abdominoplasty: An Experimental, Double-Blinded, Non-randomized Clinical Trial

Abstract

Background

Photobiomodulation is widely studied for its potential benefits in the wound healing process. Numerous scientific studies have highlighted its effect on various phases of wound repair, but clinical validations are few. This comparative trial aims to evaluate the influence of photobiomodulation on the post-abdominoplasty healing process.

Methods

Seventeen Caucasian women (aged 18–55) who underwent an abdominoplasty were enrolled in this double-blinded, controlled clinical trial. The postoperative scars were divided into two areas; the right side of the scars was treated with ten sessions of photobiomodulation (consisting in three types of wavelengths). The other part of the scars was used as control and did not receive any additional treatment. Clinical assessments of both parts of the scars were scheduled at 1, 6 and 12 months postoperative.

Results

Within six months following surgery, significantly improved quality of the scars on the treated side compared with the untreated side was reported by patients and experienced professionals according to Vancouver Scar Scale, Patient and Observer Scar Assessment Scale (p < 0.05) and standardized photographs (p < 0.05). At 1 year of follow-up, patients observed no differences between the treated and untreated sides of the scars. This suggests that photobiomodulation appears to play an early role in the wound healing process, accelerating the first stages of cicatrization.

Conclusion

This study statistically validates the positive impact of photobiomodulation treatment on the first stages of the postoperative healing process. Carried out on Caucasians participants only, this study should, however, be performed on a more heterogeneous population to definitively confirm these effects on an international population.

Clinical trial registry

Registro Brasileiro de ensaios clínicos: http://www.ensaiosclinicos.gov.br, Trial RBR-49PK78.

Level of Evidence II

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPajIp

Secondary Breast Augmentation: Is there a Trend for Bigger Implants?

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TWniYW

Levator Pull-Out Suture Technique for Immediate Postoperative Correction of Eyelid Asymmetry After Ptosis Surgery in Asians

Abstract

Background

Postoperative eyelid asymmetry is the most common complaint of patients after undergoing blepharoplasty and ptosis correction surgery. Calibrating eyelid asymmetry during ptosis correction surgery is still difficult for surgeons despite the development of innovative procedures. Our levator pull-out suture technique for correcting postoperative eyelid asymmetry after ptosis surgery is introduced.

Methods

A total of 330 patients who underwent ptosis correction surgery with upper blepharoplasty from 2016 to 2017 were enrolled in our study. All surgeries were performed using the levator pull-out suture technique, and the postoperative eyelid asymmetry was corrected in the outpatient clinic at 2–3 days after the operation. Patient satisfaction was evaluated preoperatively and at 1 week and 2 months postoperatively using a questionnaire. Visual acuity, marginal reflex distance 1 (MRD1), and vertical palpebral fissure length asymmetry were measured preoperatively and compared to values taken postoperatively.

Results

Patient satisfaction regarding asymmetry increased from 2.7/5 (preoperatively) to 4.1/5 points (postoperatively). MRD1 and vertical palpebral fissure length increased from 1.1/1.2 and 6.8/6.8 mm (preoperatively), respectively, to 2.8/2.9 and 8.5/8.6 mm (postoperatively), respectively. The asymmetry of MRD1 and vertical palpebral fissure length before and after surgery were corrected from 0.45/1.81 to 0.01/0.19 mm (p < 0.01).

Conclusion

Our innovative surgical method of using the levator pull-out suture technique is relatively simple and allows for finer suture adjustments postoperatively to effectively correct eyelid asymmetry, with satisfactory results.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ay2Y74

The perioperative patient on buprenorphine: a systematic review of perioperative management strategies and patient outcomes

Abstract

Background

An increasing number of patients with opioid use disorder (OUD) are treated with opioid agonist-antagonists such as buprenorphine/naloxone. Perioperative management of patients on buprenorphine/naloxone is inconsistent and remains a controversial topic with mismanagement posing a significant risk to the long-term health of these patients.

Methods

We performed a systematic literature search involving Medline, Medline In-Process, Embase, Cochrane Central, Cochrane Database of Systematic Reviews, PsycINFO, Web of Science (Clarivate), Scopus (Elsevier), CINAHL (EbscoHosst), and PubMed (NLM).

Results

Eighteen studies were included in the final sample, including one controlled study and four observational studies . Neither the controlled study nor the observational studies assessed addiction treatment retention, harm reduction, or long-term mortality rates as primary or secondary outcomes. Of the observational studies, authors showed equivalent peri- and postoperative pain control among buprenorphine continued patients. All but one authors described adequate analgesia among the case reports in which buprenorphine ≤ 16 mg sublingually (SL) daily was continued during the perioperative period. Long-term harm reduction was not reported with only three case reports including any long-term abstinence or relapse rates.

Conclusions

The current understanding of the risks and benefits of continuing or stopping buprenorphine perioperatively is limited by a lack of high-quality evidence. Observational studies and case reports indicate no evidence against continuing buprenorphine perioperatively, especially when the dose is < 16 mg SL daily. In patients with significant potential for relapse, such as those with a recent history of OUD, the discontinuation of buprenorphine should have a strong rationale supported by patient and surgical preferences. Future studies require standardized reporting of median doses, details on the route of delivery, dosing schedules and any dosing changes, and rates of addiction relapse, including long-term morbidity and mortality where possible.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r814pv

Évaluation de l’impact du projet Lifebox au Burkina Faso sur la pratique de l’oxymétrie pulsée et la check-list de l’organisation mondiale de la santé pour la sécurité du patient au bloc opératoire

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FH9GgP

The need to collect, aggregate, and analyze global anesthesia and surgery data

Abstract

In the Sustainable Development Goals era, there is a new awareness of the need for an integrated approach to healthcare interventions and a strong commitment to Universal Health Coverage. To achieve the goal of strengthening entire health systems, surgery, as a crosscutting treatment modality, is indispensable. For any health system strengthening exercise, baseline data and longitudinal monitoring of progress are necessary. With improved data capabilities, there are unparalleled possibilities to map out and understand systems, integrating data from many sources and sectors. Nevertheless, there is also a need to prioritize among indicators to avoid information overload and data collection fatigue. There is a similar need to define indicators and collection methodology to create standardized and comparable data. Finally, there is a need to establish data pathways to ensure clear responsibilities amongst national and international institutions and integrate surgical metrics into existing mechanisms for sustainable data collection. This is a call to collect, aggregate, and analyze global anesthesia and surgery data, with an account of existing data sources and a proposed way forward.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r812hn

Change in endolymphatic hydrops 2 years after endolymphatic sac surgery evaluated by MRI

This study was performed to determine whether endolymphatic sac surgery improves vestibular and cochlear endolymphatic hydrops 2 years after sac surgery and to elucidate the relationship between the degree of improvement of endolymphatic hydrops and the changes in vertigo symptoms, the hearing level, and the summating potential/action potential ratio (−SP/AP ratio) by electrocochleography (ECochG) in patients with Ménière's disease (MD).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FKgiLs

Change in endolymphatic hydrops 2 years after endolymphatic sac surgery evaluated by MRI

This study was performed to determine whether endolymphatic sac surgery improves vestibular and cochlear endolymphatic hydrops 2 years after sac surgery and to elucidate the relationship between the degree of improvement of endolymphatic hydrops and the changes in vertigo symptoms, the hearing level, and the summating potential/action potential ratio (−SP/AP ratio) by electrocochleography (ECochG) in patients with Ménière's disease (MD).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FKgiLs

Philtrum reconstruction in unilateral cleft lip repair

The philtrum is an important aesthetic structure in the midface. A number of philtrum reconstruction techniques have been advocated for secondary cleft lip revision procedures. Conventional surgical management involves end-to-end orbicularis oris muscle approximation during primary cleft lip repair, often resulting in a flat lip appearance that requires secondary revision surgery at a later stage. A novel modification of the approximation of the orbicularis oris muscle is described that may be implemented with any cleft lip technique in order to create an accentuated philtrum column for a natural looking philtrum.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2KAt3Hv

Philtrum reconstruction in unilateral cleft lip repair

The philtrum is an important aesthetic structure in the midface. A number of philtrum reconstruction techniques have been advocated for secondary cleft lip revision procedures. Conventional surgical management involves end-to-end orbicularis oris muscle approximation during primary cleft lip repair, often resulting in a flat lip appearance that requires secondary revision surgery at a later stage. A novel modification of the approximation of the orbicularis oris muscle is described that may be implemented with any cleft lip technique in order to create an accentuated philtrum column for a natural looking philtrum.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2KAt3Hv

Laundry detergents and detergent residue after rinse directly disrupt tight junction barrier integrity in human bronchial epithelial cells

Laundry detergents and rinse residue at high dilutions show a directly disruptive effect on tight junction barrier integrity of bronchial epithelial cells, suggesting a mechanism for increased penetration of pathogens, allergens and irritants through mucosa.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r9zUhX

Laundry detergents and detergent residue after rinse directly disrupt tight junction barrier integrity in human bronchial epithelial cells

Laundry detergents and rinse residue at high dilutions show a directly disruptive effect on tight junction barrier integrity of bronchial epithelial cells, suggesting a mechanism for increased penetration of pathogens, allergens and irritants through mucosa.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r9zUhX

Surgery of the major salivary glands and its impact on salivary flow —A review

ConclusionsHead and neck surgeons should inform their patients more accurately about reduced salivary flow and possible xerostomia after salivary gland surgery, and focus more on conservative strategies and minimally invasive techniques.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FLxTCL

Automated Quantification of Vocal Fold Motion in a Recurrent Laryngeal Nerve Injury Mouse Model

ConclusionsOur motion ‐analysis software provides novel objective, quantitative, and repeatable metrics to detect and describe subtle VF dysfunction in mice that corresponds with underlying RLN degeneration and recovery. Adaptation of our tracking software for use with human patients is underway.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ra1bRi

Antileukotrienes improve naso ‐ocular symptoms and biomarkers in patients with NARES and asthma

ConclusionNARES patients may benefit from treatment with montelukast. In particular, the presence of concomitant asthma may be predictive of a greater efficacy.Level of Evidence2.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FLdRIN

Smartphone telemedical emergency department consults for screening of nonacute dizziness

ConclusionsOur initial proof ‐of‐concept study shows that remote screening of BPPV is possible with high specificity. Because the DHT is easily taught, having a remote otolaryngologist interpret the resulting eye movements may increase usage of the test and may lead to cost savings.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2rax5NP

Surgery of the major salivary glands and its impact on salivary flow —A review

ConclusionsHead and neck surgeons should inform their patients more accurately about reduced salivary flow and possible xerostomia after salivary gland surgery, and focus more on conservative strategies and minimally invasive techniques.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FLxTCL

Automated Quantification of Vocal Fold Motion in a Recurrent Laryngeal Nerve Injury Mouse Model

ConclusionsOur motion ‐analysis software provides novel objective, quantitative, and repeatable metrics to detect and describe subtle VF dysfunction in mice that corresponds with underlying RLN degeneration and recovery. Adaptation of our tracking software for use with human patients is underway.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2ra1bRi

Antileukotrienes improve naso ‐ocular symptoms and biomarkers in patients with NARES and asthma

ConclusionNARES patients may benefit from treatment with montelukast. In particular, the presence of concomitant asthma may be predictive of a greater efficacy.Level of Evidence2.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FLdRIN

Smartphone telemedical emergency department consults for screening of nonacute dizziness

ConclusionsOur initial proof ‐of‐concept study shows that remote screening of BPPV is possible with high specificity. Because the DHT is easily taught, having a remote otolaryngologist interpret the resulting eye movements may increase usage of the test and may lead to cost savings.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2rax5NP

Teva ’s Generic EpiPen Will Cost Just As Much As Mylan’s Authorized Generic

Teva Pharmaceutical Industries announced Tuesday that its much-anticipated generic EpiPen is now available "in limited quantity" in the U.S. — at the same $300 list price as manufacturer Mylan's authorized generic version. Teva was in August granted Food and Drug Administration (FDA) approval for the first generic version of the EpiPen and lower-dose EpiPen Jr. The approval was heralded as a win for patient choice, as the generic would offer allergy sufferers an alternative to Mylan's version of the anaphylaxis-reversing auto-injector, which had over time risen in price to cost $608 for a two-pack. FDA Commissioner Dr. Scott Gottlieb said in a statement at the time that, "This approval means patients living with severe allergies who require constant acce...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfZSJ

Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria

In real-world patients with chronic idiopathic urticaria (CIU), omalizumab meets or exceeds the safety and efficacy results seen in clinical trials, researchers say.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r98gSw

Cancer under pressure: Visualizing the activity of the immune system on tumor development

(Institut Pasteur) As tumors develop, they evolve genetically. How does the immune system act when faced with tumor cells? How does it exert pressure on the genetic diversity of cancer cells? Scientists from the Institut Pasteur and Inserm used in vivo video techniques and cell-specific staining to visualize the action of immune cells in response to the proliferation of cancer cells. The findings have been published in the journal Science Immunology on Nov. 23, 2018. (Source: EurekAlert! - Cancer)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfuYR

Another EpiPen Is Now on the Market

Teva Pharmaceuticals has finally launched its generic version of Mylanâs EpiPen.  The Petah, Tikvah, Israel-based companyâs emergency allergy shot will be priced at $300 â the same as Mylanâs generic. Teva received approval for its version of EpiPen in August. The generic will be available in limited supply and the company will launch a lower-dose - the EpiPen Jr. sometime next year, the company said. âWeâre pleased to provide access to Epinephrine Injection (Auto-Injector) for patients who may experience life-threatening allergic emergencies and weâre fully dedicated toward ensuring additional supply in 2019,â Brendan Oâ...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Av2EWZ

Teva ’s Generic EpiPen Will Cost Just As Much As Mylan’s Authorized Generic

Teva Pharmaceutical Industries announced Tuesday that its much-anticipated generic EpiPen is now available "in limited quantity" in the U.S. — at the same $300 list price as manufacturer Mylan's authorized generic version. Teva was in August granted Food and Drug Administration (FDA) approval for the first generic version of the EpiPen and lower-dose EpiPen Jr. The approval was heralded as a win for patient choice, as the generic would offer allergy sufferers an alternative to Mylan's version of the anaphylaxis-reversing auto-injector, which had over time risen in price to cost $608 for a two-pack. FDA Commissioner Dr. Scott Gottlieb said in a statement at the time that, "This approval means patients living with severe allergies who require constant acce...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfZSJ

Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria

In real-world patients with chronic idiopathic urticaria (CIU), omalizumab meets or exceeds the safety and efficacy results seen in clinical trials, researchers say.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r98gSw

Trial of investigational Ebola treatments begins in Democratic Republic of the Congo

(NIH/National Institute of Allergy and Infectious Diseases) An international team has begun patient enrollment in a clinical trial testing investigational Ebola therapies in the Democratic Republic of the Congo. The randomized, controlled trial is enrolling patients of any age with confirmed Ebola virus disease (DRC). The trial is led and funded by the National Institute for Biomedical Research, part of the DRC Ministry of Health, and the National Institute of Allergy and Infectious Diseases (NIAID). (Source: EurekAlert! - Infectious and Emerging Diseases)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Av2vTr

Cancer under pressure: Visualizing the activity of the immune system on tumor development

(Institut Pasteur) As tumors develop, they evolve genetically. How does the immune system act when faced with tumor cells? How does it exert pressure on the genetic diversity of cancer cells? Scientists from the Institut Pasteur and Inserm used in vivo video techniques and cell-specific staining to visualize the action of immune cells in response to the proliferation of cancer cells. The findings have been published in the journal Science Immunology on Nov. 23, 2018. (Source: EurekAlert! - Cancer)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfuYR

Fluorescence imaging of invasive head and neck carcinoma cells with integrin αvβ6-targeting RGD-peptides: an approach to a fluorescence-assisted intraoperative cytological assessment of bony resection margins

We assessed the use of peptides containing arginylglycylaspartic acid (RGD) that target integrin αvβ6 as a potential approach for a fluorescence-assisted intraoperative cytological assessment of bony resection margins (F-AICAB) in patients who had bone-infiltrating squamous cell carcinoma (SCC) of the head and neck. This was assessed to demarcate invasive carcinoma cells that stained for αvβ6. Specimens from bony resection margins (n=362) were defined as either malignant or benign according to the results of cytological and histological examinations.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5Yw50

Another EpiPen Is Now on the Market

Teva Pharmaceuticals has finally launched its generic version of Mylanâs EpiPen.  The Petah, Tikvah, Israel-based companyâs emergency allergy shot will be priced at $300 â the same as Mylanâs generic. Teva received approval for its version of EpiPen in August. The generic will be available in limited supply and the company will launch a lower-dose - the EpiPen Jr. sometime next year, the company said. âWeâre pleased to provide access to Epinephrine Injection (Auto-Injector) for patients who may experience life-threatening allergic emergencies and weâre fully dedicated toward ensuring additional supply in 2019,â Brendan Oâ...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Av2EWZ

Teva ’s Generic EpiPen Will Cost Just As Much As Mylan’s Authorized Generic

Teva Pharmaceutical Industries announced Tuesday that its much-anticipated generic EpiPen is now available "in limited quantity" in the U.S. — at the same $300 list price as manufacturer Mylan's authorized generic version. Teva was in August granted Food and Drug Administration (FDA) approval for the first generic version of the EpiPen and lower-dose EpiPen Jr. The approval was heralded as a win for patient choice, as the generic would offer allergy sufferers an alternative to Mylan's version of the anaphylaxis-reversing auto-injector, which had over time risen in price to cost $608 for a two-pack. FDA Commissioner Dr. Scott Gottlieb said in a statement at the time that, "This approval means patients living with severe allergies who require constant acce...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfZSJ

Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria

In real-world patients with chronic idiopathic urticaria (CIU), omalizumab meets or exceeds the safety and efficacy results seen in clinical trials, researchers say.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r98gSw

Trial of investigational Ebola treatments begins in Democratic Republic of the Congo

(NIH/National Institute of Allergy and Infectious Diseases) An international team has begun patient enrollment in a clinical trial testing investigational Ebola therapies in the Democratic Republic of the Congo. The randomized, controlled trial is enrolling patients of any age with confirmed Ebola virus disease (DRC). The trial is led and funded by the National Institute for Biomedical Research, part of the DRC Ministry of Health, and the National Institute of Allergy and Infectious Diseases (NIAID). (Source: EurekAlert! - Infectious and Emerging Diseases)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Av2vTr

Cancer under pressure: Visualizing the activity of the immune system on tumor development

(Institut Pasteur) As tumors develop, they evolve genetically. How does the immune system act when faced with tumor cells? How does it exert pressure on the genetic diversity of cancer cells? Scientists from the Institut Pasteur and Inserm used in vivo video techniques and cell-specific staining to visualize the action of immune cells in response to the proliferation of cancer cells. The findings have been published in the journal Science Immunology on Nov. 23, 2018. (Source: EurekAlert! - Cancer)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfuYR

Another EpiPen Is Now on the Market

Teva Pharmaceuticals has finally launched its generic version of Mylanâs EpiPen.  The Petah, Tikvah, Israel-based companyâs emergency allergy shot will be priced at $300 â the same as Mylanâs generic. Teva received approval for its version of EpiPen in August. The generic will be available in limited supply and the company will launch a lower-dose - the EpiPen Jr. sometime next year, the company said. âWeâre pleased to provide access to Epinephrine Injection (Auto-Injector) for patients who may experience life-threatening allergic emergencies and weâre fully dedicated toward ensuring additional supply in 2019,â Brendan Oâ...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Av2EWZ

Teva ’s Generic EpiPen Will Cost Just As Much As Mylan’s Authorized Generic

Teva Pharmaceutical Industries announced Tuesday that its much-anticipated generic EpiPen is now available "in limited quantity" in the U.S. — at the same $300 list price as manufacturer Mylan's authorized generic version. Teva was in August granted Food and Drug Administration (FDA) approval for the first generic version of the EpiPen and lower-dose EpiPen Jr. The approval was heralded as a win for patient choice, as the generic would offer allergy sufferers an alternative to Mylan's version of the anaphylaxis-reversing auto-injector, which had over time risen in price to cost $608 for a two-pack. FDA Commissioner Dr. Scott Gottlieb said in a statement at the time that, "This approval means patients living with severe allergies who require constant acce...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfZSJ

Triple Therapy for COPD Cuts Exacerbations, May Up Pneumonia Risk Triple Therapy for COPD Cuts Exacerbations, May Up Pneumonia Risk

Triple therapy reduces chronic obstructive pulmonary disease (COPD) exacerbations and improves lung function and quality of life more than dual therapy or monotherapy in patients with advanced COPD, according to a new review and meta-analysis.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FK38hN

Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria

In real-world patients with chronic idiopathic urticaria (CIU), omalizumab meets or exceeds the safety and efficacy results seen in clinical trials, researchers say.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r98gSw

Trial of investigational Ebola treatments begins in Democratic Republic of the Congo

(NIH/National Institute of Allergy and Infectious Diseases) An international team has begun patient enrollment in a clinical trial testing investigational Ebola therapies in the Democratic Republic of the Congo. The randomized, controlled trial is enrolling patients of any age with confirmed Ebola virus disease (DRC). The trial is led and funded by the National Institute for Biomedical Research, part of the DRC Ministry of Health, and the National Institute of Allergy and Infectious Diseases (NIAID). (Source: EurekAlert! - Infectious and Emerging Diseases)

MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Av2vTr

Cancer under pressure: Visualizing the activity of the immune system on tumor development

(Institut Pasteur) As tumors develop, they evolve genetically. How does the immune system act when faced with tumor cells? How does it exert pressure on the genetic diversity of cancer cells? Scientists from the Institut Pasteur and Inserm used in vivo video techniques and cell-specific staining to visualize the action of immune cells in response to the proliferation of cancer cells. The findings have been published in the journal Science Immunology on Nov. 23, 2018. (Source: EurekAlert! - Cancer)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TPfuYR

Fluorescence imaging of invasive head and neck carcinoma cells with integrin αvβ6-targeting RGD-peptides: an approach to a fluorescence-assisted intraoperative cytological assessment of bony resection margins

We assessed the use of peptides containing arginylglycylaspartic acid (RGD) that target integrin αvβ6 as a potential approach for a fluorescence-assisted intraoperative cytological assessment of bony resection margins (F-AICAB) in patients who had bone-infiltrating squamous cell carcinoma (SCC) of the head and neck. This was assessed to demarcate invasive carcinoma cells that stained for αvβ6. Specimens from bony resection margins (n=362) were defined as either malignant or benign according to the results of cytological and histological examinations.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5Yw50

Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsBErg

How Should Thyroid-Related Quality of Life Be Assessed? Recalled Patient-Reported Outcomes Compared to Here-and-Now Measures

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5nlO8

An Age-Specific Serum Thyrotropin Reference Range for the Diagnosis of Thyroid Diseases in Older Adults: A Cross-Sectional Survey in China

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zwPh8K

Comparison of Iodine Concentrations in Kitchen Salt and Urine with the Thyroid Volume of Schoolchildren from Ribeirão Preto, São Paulo, Brazil: Warning of Worsening After 10 Years of Study

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P59mYM

A friend in need: evaluating the impact of Lifebox in Burkina Faso

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QjK3Hj

A Systematic Review and Meta-Analysis of Subsequent Malignant Neoplasm Risk After Radioactive Iodine Treatment of Thyroid Cancer

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5Ljcq

Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsBErg

How Should Thyroid-Related Quality of Life Be Assessed? Recalled Patient-Reported Outcomes Compared to Here-and-Now Measures

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5nlO8

An Age-Specific Serum Thyrotropin Reference Range for the Diagnosis of Thyroid Diseases in Older Adults: A Cross-Sectional Survey in China

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zwPh8K

A friend in need: evaluating the impact of Lifebox in Burkina Faso

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QjK3Hj

Meta-Analysis Should be Done in a Normative Manner

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SeaxXW

High- and Extra-High-Profile Round Implants in Breast Augmentation: Guidelines to Prevent Rippling and Implant Edge Visibility

Abstract

Background

Rippling and implant edge visibility after breast augmentation depends on several factors. Among the most relevant are breast soft tissue thickness, particularly the retroareolar mammary parenchyma, and implant profile. They were correlates to prevent these occurrences.

Methods

Thirty patients underwent breast augmentation through subfascial dissection involving the pectoralis, serratus, external oblique, and rectus abdominis fascias. The thickness of the retroareolar mammary parenchyma distributed patients into two groups. Group I: patients with thickness equal to or greater than 4.0 cm received high-profile 85% fill round implants. Group II: patients with thickness up to 3.9 cm received extra-high-profile 100% fill round implants. MRI was performed preoperatively and 5 years after augmentation to evaluate breast tissue changes and implant contouring.

Results

Seventeen patients with high-profile implants and thirteen patients with extra-high-profile implants had noticeable improvement of the breasts without the occurrence of rippling or implant edge visibility. A natural appearance of the breast, increased mammary cone, balanced upper and lower pole contouring was maintained at 5 years postoperatively. MRI performed 5 years after breast augmentation validated patient clinical outcomes not evidencing implant deformities, or soft tissue thinning, parenchymal atrophy or chest wall deformities.

Conclusions

The adequate correlation between retroareolar mammary parenchyma thickness with high-profile 85% fill and extra-high-profile 100% fill textured round implants was of utmost importance in preventing rippling and implant edge visibility. The wide fascial support, width of the implant smaller than the breast diameter, and soft cohesive gel-filled implants were co-adjuvant factors in preventing rippling and implant edge visibility.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DZIubG

Evaluation of Glandular Liposculpture as a Single Treatment for Grades I and II Gynecomastia

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SgABBQ

Meta-Analysis Should be Done in a Normative Manner

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SeaxXW

High- and Extra-High-Profile Round Implants in Breast Augmentation: Guidelines to Prevent Rippling and Implant Edge Visibility

Abstract

Background

Rippling and implant edge visibility after breast augmentation depends on several factors. Among the most relevant are breast soft tissue thickness, particularly the retroareolar mammary parenchyma, and implant profile. They were correlates to prevent these occurrences.

Methods

Thirty patients underwent breast augmentation through subfascial dissection involving the pectoralis, serratus, external oblique, and rectus abdominis fascias. The thickness of the retroareolar mammary parenchyma distributed patients into two groups. Group I: patients with thickness equal to or greater than 4.0 cm received high-profile 85% fill round implants. Group II: patients with thickness up to 3.9 cm received extra-high-profile 100% fill round implants. MRI was performed preoperatively and 5 years after augmentation to evaluate breast tissue changes and implant contouring.

Results

Seventeen patients with high-profile implants and thirteen patients with extra-high-profile implants had noticeable improvement of the breasts without the occurrence of rippling or implant edge visibility. A natural appearance of the breast, increased mammary cone, balanced upper and lower pole contouring was maintained at 5 years postoperatively. MRI performed 5 years after breast augmentation validated patient clinical outcomes not evidencing implant deformities, or soft tissue thinning, parenchymal atrophy or chest wall deformities.

Conclusions

The adequate correlation between retroareolar mammary parenchyma thickness with high-profile 85% fill and extra-high-profile 100% fill textured round implants was of utmost importance in preventing rippling and implant edge visibility. The wide fascial support, width of the implant smaller than the breast diameter, and soft cohesive gel-filled implants were co-adjuvant factors in preventing rippling and implant edge visibility.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DZIubG

Evaluation of Glandular Liposculpture as a Single Treatment for Grades I and II Gynecomastia

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SgABBQ

Triple Therapy for COPD Cuts Exacerbations, May Up Pneumonia Risk Triple Therapy for COPD Cuts Exacerbations, May Up Pneumonia Risk

Triple therapy reduces chronic obstructive pulmonary disease (COPD) exacerbations and improves lung function and quality of life more than dual therapy or monotherapy in patients with advanced COPD, according to a new review and meta-analysis.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FK38hN

Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria

In real-world patients with chronic idiopathic urticaria (CIU), omalizumab meets or exceeds the safety and efficacy results seen in clinical trials, researchers say.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r98gSw

EpiPens Withstand 24 Hours of Freezing EpiPens Withstand 24 Hours of Freezing

Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0Cwas

Thoracic Lymph Node Map App Review

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FJhPRX

A Platform Integrating Acquisition, Reconstruction, Visualization, and Manipulator Control Modules for MRI-Guided Interventions

Abstract

This work presents a platform that integrates a customized MRI data acquisition scheme with reconstruction and three-dimensional (3D) visualization modules along with a module for controlling an MRI-compatible robotic device to facilitate the performance of robot-assisted, MRI-guided interventional procedures. Using dynamically-acquired MRI data, the computational framework of the platform generates and updates a 3D model representing the area of the procedure (AoP). To image structures of interest in the AoP that do not reside inside the same or parallel slices, the MRI acquisition scheme was modified to collect a multi-slice set of intraoblique to each other slices; which are termed composing slices. Moreover, this approach interleaves the collection of the composing slices so the same k-space segments of all slices are collected during similar time instances. This time matching of the k-space segments results in spatial matching of the imaged objects in the individual composing slices. The composing slices were used to generate and update the 3D model of the AoP. The MRI acquisition scheme was evaluated with computer simulations and experimental studies. Computer simulations demonstrated that k-space segmentation and time-matched interleaved acquisition of these segments provide spatial matching of the structures imaged with composing slices. Experimental studies used the platform to image the maneuvering of an MRI-compatible manipulator that carried tubing filled with MRI contrast agent. In vivo experimental studies to image the abdomen and contrast enhanced heart on free-breathing subjects without cardiac triggering demonstrated spatial matching of imaged anatomies in the composing planes. The described interventional MRI framework could assist in performing real-time MRI-guided interventions.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2rapUVT

Triple Therapy for COPD Cuts Exacerbations, May Up Pneumonia Risk Triple Therapy for COPD Cuts Exacerbations, May Up Pneumonia Risk

Triple therapy reduces chronic obstructive pulmonary disease (COPD) exacerbations and improves lung function and quality of life more than dual therapy or monotherapy in patients with advanced COPD, according to a new review and meta-analysis.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FK38hN

Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria Omalizumab Seems Safe, Effective for Real-World Chronic Idiopathic Urticaria

In real-world patients with chronic idiopathic urticaria (CIU), omalizumab meets or exceeds the safety and efficacy results seen in clinical trials, researchers say.Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2r98gSw

EpiPens Withstand 24 Hours of Freezing EpiPens Withstand 24 Hours of Freezing

Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0Cwas

Thoracic Lymph Node Map App Review

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FJhPRX

A Platform Integrating Acquisition, Reconstruction, Visualization, and Manipulator Control Modules for MRI-Guided Interventions

Abstract

This work presents a platform that integrates a customized MRI data acquisition scheme with reconstruction and three-dimensional (3D) visualization modules along with a module for controlling an MRI-compatible robotic device to facilitate the performance of robot-assisted, MRI-guided interventional procedures. Using dynamically-acquired MRI data, the computational framework of the platform generates and updates a 3D model representing the area of the procedure (AoP). To image structures of interest in the AoP that do not reside inside the same or parallel slices, the MRI acquisition scheme was modified to collect a multi-slice set of intraoblique to each other slices; which are termed composing slices. Moreover, this approach interleaves the collection of the composing slices so the same k-space segments of all slices are collected during similar time instances. This time matching of the k-space segments results in spatial matching of the imaged objects in the individual composing slices. The composing slices were used to generate and update the 3D model of the AoP. The MRI acquisition scheme was evaluated with computer simulations and experimental studies. Computer simulations demonstrated that k-space segmentation and time-matched interleaved acquisition of these segments provide spatial matching of the structures imaged with composing slices. Experimental studies used the platform to image the maneuvering of an MRI-compatible manipulator that carried tubing filled with MRI contrast agent. In vivo experimental studies to image the abdomen and contrast enhanced heart on free-breathing subjects without cardiac triggering demonstrated spatial matching of imaged anatomies in the composing planes. The described interventional MRI framework could assist in performing real-time MRI-guided interventions.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2rapUVT

EpiPens Withstand 24 Hours of Freezing EpiPens Withstand 24 Hours of Freezing

Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0Cwas

Meta-Analysis Should be Done in a Normative Manner

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SeaxXW

High- and Extra-High-Profile Round Implants in Breast Augmentation: Guidelines to Prevent Rippling and Implant Edge Visibility

Abstract

Background

Rippling and implant edge visibility after breast augmentation depends on several factors. Among the most relevant are breast soft tissue thickness, particularly the retroareolar mammary parenchyma, and implant profile. They were correlates to prevent these occurrences.

Methods

Thirty patients underwent breast augmentation through subfascial dissection involving the pectoralis, serratus, external oblique, and rectus abdominis fascias. The thickness of the retroareolar mammary parenchyma distributed patients into two groups. Group I: patients with thickness equal to or greater than 4.0 cm received high-profile 85% fill round implants. Group II: patients with thickness up to 3.9 cm received extra-high-profile 100% fill round implants. MRI was performed preoperatively and 5 years after augmentation to evaluate breast tissue changes and implant contouring.

Results

Seventeen patients with high-profile implants and thirteen patients with extra-high-profile implants had noticeable improvement of the breasts without the occurrence of rippling or implant edge visibility. A natural appearance of the breast, increased mammary cone, balanced upper and lower pole contouring was maintained at 5 years postoperatively. MRI performed 5 years after breast augmentation validated patient clinical outcomes not evidencing implant deformities, or soft tissue thinning, parenchymal atrophy or chest wall deformities.

Conclusions

The adequate correlation between retroareolar mammary parenchyma thickness with high-profile 85% fill and extra-high-profile 100% fill textured round implants was of utmost importance in preventing rippling and implant edge visibility. The wide fascial support, width of the implant smaller than the breast diameter, and soft cohesive gel-filled implants were co-adjuvant factors in preventing rippling and implant edge visibility.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DZIubG

Evaluation of Glandular Liposculpture as a Single Treatment for Grades I and II Gynecomastia

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SgABBQ

Teva prices EpiPen generic at $300, same price as Mylan generic

Teva Pharmaceutical Industries Ltd said on Tuesday it launched its generic version of Mylan NV's EpiPen at the wholesale price of $300 - the same price as Mylan's generic version of the emergency allergy shot. (Source: Reuters: Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0CuiQ

ACA Coverage Substantial, but Did Not Impact Labor Markets

Coverage gains did not negatively impact employment levels, hours worked, earnings (Source: The Doctors Lounge - Psychiatry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SiA42j

Holidays a Challenge for Those With Allergies

Title: Holidays a Challenge for Those With AllergiesCategory: Health NewsCreated: 11/24/2018 12:00:00 AMLast Editorial Review: 11/26/2018 12:00:00 AM (Source: MedicineNet Allergies General)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SizXDV

Teva prices EpiPen generic at $300, same price as Mylan generic

Teva Pharmaceutical Industries Ltd said on Tuesday it launched its generic version of Mylan NV's EpiPen at the wholesale price of $300 - the same price as Mylan's generic version of the emergency allergy shot. (Source: Reuters: Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0CuiQ

ACA Coverage Substantial, but Did Not Impact Labor Markets

Coverage gains did not negatively impact employment levels, hours worked, earnings (Source: The Doctors Lounge - Psychiatry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SiA42j

EpiPens Withstand 24 Hours of Freezing EpiPens Withstand 24 Hours of Freezing

Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0Cwas

Holidays a Challenge for Those With Allergies

Title: Holidays a Challenge for Those With AllergiesCategory: Health NewsCreated: 11/24/2018 12:00:00 AMLast Editorial Review: 11/26/2018 12:00:00 AM (Source: MedicineNet Allergies General)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SizXDV

Meta-Analysis Should be Done in a Normative Manner

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SeaxXW

High- and Extra-High-Profile Round Implants in Breast Augmentation: Guidelines to Prevent Rippling and Implant Edge Visibility

Abstract

Background

Rippling and implant edge visibility after breast augmentation depends on several factors. Among the most relevant are breast soft tissue thickness, particularly the retroareolar mammary parenchyma, and implant profile. They were correlates to prevent these occurrences.

Methods

Thirty patients underwent breast augmentation through subfascial dissection involving the pectoralis, serratus, external oblique, and rectus abdominis fascias. The thickness of the retroareolar mammary parenchyma distributed patients into two groups. Group I: patients with thickness equal to or greater than 4.0 cm received high-profile 85% fill round implants. Group II: patients with thickness up to 3.9 cm received extra-high-profile 100% fill round implants. MRI was performed preoperatively and 5 years after augmentation to evaluate breast tissue changes and implant contouring.

Results

Seventeen patients with high-profile implants and thirteen patients with extra-high-profile implants had noticeable improvement of the breasts without the occurrence of rippling or implant edge visibility. A natural appearance of the breast, increased mammary cone, balanced upper and lower pole contouring was maintained at 5 years postoperatively. MRI performed 5 years after breast augmentation validated patient clinical outcomes not evidencing implant deformities, or soft tissue thinning, parenchymal atrophy or chest wall deformities.

Conclusions

The adequate correlation between retroareolar mammary parenchyma thickness with high-profile 85% fill and extra-high-profile 100% fill textured round implants was of utmost importance in preventing rippling and implant edge visibility. The wide fascial support, width of the implant smaller than the breast diameter, and soft cohesive gel-filled implants were co-adjuvant factors in preventing rippling and implant edge visibility.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DZIubG

Evaluation of Glandular Liposculpture as a Single Treatment for Grades I and II Gynecomastia

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SgABBQ

ACA Coverage Substantial, but Did Not Impact Labor Markets

Coverage gains did not negatively impact employment levels, hours worked, earnings (Source: The Doctors Lounge - Psychiatry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SiA42j

EpiPens Withstand 24 Hours of Freezing EpiPens Withstand 24 Hours of Freezing

Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0Cwas

Holidays a Challenge for Those With Allergies

Title: Holidays a Challenge for Those With AllergiesCategory: Health NewsCreated: 11/24/2018 12:00:00 AMLast Editorial Review: 11/26/2018 12:00:00 AM (Source: MedicineNet Allergies General)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SizXDV

Teva prices EpiPen generic at $300, same price as Mylan generic

Teva Pharmaceutical Industries Ltd said on Tuesday it launched its generic version of Mylan NV's EpiPen at the wholesale price of $300 - the same price as Mylan's generic version of the emergency allergy shot. (Source: Reuters: Health)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0CuiQ

ACA Coverage Substantial, but Did Not Impact Labor Markets

Coverage gains did not negatively impact employment levels, hours worked, earnings (Source: The Doctors Lounge - Psychiatry)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SiA42j

EpiPens Withstand 24 Hours of Freezing EpiPens Withstand 24 Hours of Freezing

Reuters Health Information (Source: Medscape Allergy Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E0Cwas

Holidays a Challenge for Those With Allergies

Title: Holidays a Challenge for Those With AllergiesCategory: Health NewsCreated: 11/24/2018 12:00:00 AMLast Editorial Review: 11/26/2018 12:00:00 AM (Source: MedicineNet Allergies General)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2SizXDV

Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsBErg

A Systematic Review and Meta-Analysis of Subsequent Malignant Neoplasm Risk After Radioactive Iodine Treatment of Thyroid Cancer

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zp3iFy

Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P6EzuA

How Should Thyroid-Related Quality of Life Be Assessed? Recalled Patient-Reported Outcomes Compared to Here-and-Now Measures

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zp3bd6

An Age-Specific Serum Thyrotropin Reference Range for the Diagnosis of Thyroid Diseases in Older Adults: A Cross-Sectional Survey in China

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P2AJmo

Comparison of Iodine Concentrations in Kitchen Salt and Urine with the Thyroid Volume of Schoolchildren from Ribeirão Preto, São Paulo, Brazil: Warning of Worsening After 10 Years of Study

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zwPhFM

A Systematic Review and Meta-Analysis of Subsequent Malignant Neoplasm Risk After Radioactive Iodine Treatment of Thyroid Cancer

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5Ljcq

How Should Thyroid-Related Quality of Life Be Assessed? Recalled Patient-Reported Outcomes Compared to Here-and-Now Measures

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5nlO8

An Age-Specific Serum Thyrotropin Reference Range for the Diagnosis of Thyroid Diseases in Older Adults: A Cross-Sectional Survey in China

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zwPh8K

Comparison of Iodine Concentrations in Kitchen Salt and Urine with the Thyroid Volume of Schoolchildren from Ribeirão Preto, São Paulo, Brazil: Warning of Worsening After 10 Years of Study

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P59mYM

A Systematic Review and Meta-Analysis of Subsequent Malignant Neoplasm Risk After Radioactive Iodine Treatment of Thyroid Cancer

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zp3iFy

Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P6EzuA

How Should Thyroid-Related Quality of Life Be Assessed? Recalled Patient-Reported Outcomes Compared to Here-and-Now Measures

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zp3bd6

An Age-Specific Serum Thyrotropin Reference Range for the Diagnosis of Thyroid Diseases in Older Adults: A Cross-Sectional Survey in China

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P2AJmo

Comparison of Iodine Concentrations in Kitchen Salt and Urine with the Thyroid Volume of Schoolchildren from Ribeirão Preto, São Paulo, Brazil: Warning of Worsening After 10 Years of Study

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zwPhFM

A Systematic Review and Meta-Analysis of Subsequent Malignant Neoplasm Risk After Radioactive Iodine Treatment of Thyroid Cancer

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5Ljcq

Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zsBErg

How Should Thyroid-Related Quality of Life Be Assessed? Recalled Patient-Reported Outcomes Compared to Here-and-Now Measures

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P5nlO8

An Age-Specific Serum Thyrotropin Reference Range for the Diagnosis of Thyroid Diseases in Older Adults: A Cross-Sectional Survey in China

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zwPh8K

Comparison of Iodine Concentrations in Kitchen Salt and Urine with the Thyroid Volume of Schoolchildren from Ribeirão Preto, São Paulo, Brazil: Warning of Worsening After 10 Years of Study

Thyroid, Ahead of Print.


from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2P59mYM

Smartphone telemedical emergency department consults for screening of nonacute dizziness

Objectives/Hypothesis

Each year, the United States spends over $4 billion on emergency department visits for evaluation of dizziness. Benign paroxysmal positional vertigo (BPPV) is a common cause of dizziness that can easily be diagnosed by observing characteristic eye movements during the Dix‐Hallpike test (DHT). The DHT is easily performed; however, interpretation requires more advanced training. This may be part of the reason it is not commonly performed in emergency departments, and instead, patients undergo costly imaging tests. We evaluated whether smartphone‐based video recordings of DHT could be assessed telemedically for screening of nonacute dizziness.

Study Design

Feasibility study.

Methods

Dizzy patients underwent objective vestibular testing, but also had videos of their eye movements recorded via a smartphone during the DHT. The videos were remotely reviewed by two neuro‐otologists for BPPV screening and were compared to objective and in‐person exam findings.

Results

Overall, 30 dizzy patients were evaluated with seven cases of BPPV. The sensitivity for diagnosing BPPV via a smartphone‐recording of eye movements of the DHT was 92.86%, with a specificity of 100% and a negative predictive value of 97.87%.

Conclusions

Our initial proof‐of‐concept study shows that remote screening of BPPV is possible with high specificity. Because the DHT is easily taught, having a remote otolaryngologist interpret the resulting eye movements may increase usage of the test and may lead to cost savings.

Level of Evidence

4 Laryngoscope, 2018

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QmLCEl