Objectives: Emotional communication is a cornerstone of social cognition and informs human interaction. Previous studies have shown deficits in facial and vocal emotion recognition in older adults, particularly for negative emotions. However, few studies have examined combined effects of aging and hearing loss on vocal emotion recognition by adults. The objective of this study was to compare vocal emotion recognition in adults with hearing loss relative to age-matched peers with normal hearing. We hypothesized that age would play a role in emotion recognition and that listeners with hearing loss would show deficits across the age range. Design: Thirty-two adults (22 to 74 years of age) with mild to severe, symmetrical sensorineural hearing loss, amplified with bilateral hearing aids and 30 adults (21 to 75 years of age) with normal hearing, participated in the study. Stimuli consisted of sentences spoken by 2 talkers, 1 male, 1 female, in 5 emotions (angry, happy, neutral, sad, and scared) in an adult-directed manner. The task involved a single-interval, five-alternative forced-choice paradigm, in which the participants listened to individual sentences and indicated which of the five emotions was targeted in each sentence. Reaction time was recorded as an indirect measure of cognitive load. Results: Results showed significant effects of age. Older listeners had reduced accuracy, increased reaction times, and reduced d' values. Normal hearing listeners showed an Age by Talker interaction where older listeners had more difficulty identifying male vocal emotion. Listeners with hearing loss showed reduced accuracy, increased reaction times, and lower d' values compared with age-matched normal-hearing listeners. Within the group with hearing loss, age and talker effects were significant, and low-frequency pure-tone averages showed a marginally significant effect. Contrary to other studies, once hearing thresholds were taken into account, no effects of listener sex were observed, nor were there effects of individual emotions on accuracy. However, reaction times and d' values showed significant differences between individual emotions. Conclusions: The results of this study confirm existing findings in the literature showing that older adults show significant deficits in voice emotion recognition compared with their normally hearing peers, and that among listeners with normal hearing, age-related changes in hearing do not predict this age-related deficit. The present results also add to the literature by showing that hearing impairment contributes additionally to deficits in vocal emotion recognition, separate from deficits related to age. These effects of age and hearing loss appear to be quite robust, being evident in reduced accuracy scores and d' measures, as well as in reaction time measures. ACKNOWLEDGMENTS: This research was funded by National Institutes of Health (NIH) Grant R01 DC014233, the Clinical Management Core of NIH Grant P20 GM10923 and the Human Research Subject Core of P30 DC004662. Portions of this study were presented at the Midwinter Meeting of the Association for Research in Otolaryngology held in San Diego, CA on February 9–14, 2018. The authors have no conflicts of interest to disclose. Address for correspondence: Monita Chatterjee, Auditory Prostheses and Perception Lab, Boys Town National Research Hospital, 425 N 30th St, Omaha, NE 68131, USA. E-mail: monita.chatterjee@boystown.org Received April 18, 2018; accepted November 20, 2018. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.
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Παρασκευή 4 Ιανουαρίου 2019
Effects of Age and Hearing Loss on the Recognition of Emotions in Speech
Objectives: Emotional communication is a cornerstone of social cognition and informs human interaction. Previous studies have shown deficits in facial and vocal emotion recognition in older adults, particularly for negative emotions. However, few studies have examined combined effects of aging and hearing loss on vocal emotion recognition by adults. The objective of this study was to compare vocal emotion recognition in adults with hearing loss relative to age-matched peers with normal hearing. We hypothesized that age would play a role in emotion recognition and that listeners with hearing loss would show deficits across the age range. Design: Thirty-two adults (22 to 74 years of age) with mild to severe, symmetrical sensorineural hearing loss, amplified with bilateral hearing aids and 30 adults (21 to 75 years of age) with normal hearing, participated in the study. Stimuli consisted of sentences spoken by 2 talkers, 1 male, 1 female, in 5 emotions (angry, happy, neutral, sad, and scared) in an adult-directed manner. The task involved a single-interval, five-alternative forced-choice paradigm, in which the participants listened to individual sentences and indicated which of the five emotions was targeted in each sentence. Reaction time was recorded as an indirect measure of cognitive load. Results: Results showed significant effects of age. Older listeners had reduced accuracy, increased reaction times, and reduced d' values. Normal hearing listeners showed an Age by Talker interaction where older listeners had more difficulty identifying male vocal emotion. Listeners with hearing loss showed reduced accuracy, increased reaction times, and lower d' values compared with age-matched normal-hearing listeners. Within the group with hearing loss, age and talker effects were significant, and low-frequency pure-tone averages showed a marginally significant effect. Contrary to other studies, once hearing thresholds were taken into account, no effects of listener sex were observed, nor were there effects of individual emotions on accuracy. However, reaction times and d' values showed significant differences between individual emotions. Conclusions: The results of this study confirm existing findings in the literature showing that older adults show significant deficits in voice emotion recognition compared with their normally hearing peers, and that among listeners with normal hearing, age-related changes in hearing do not predict this age-related deficit. The present results also add to the literature by showing that hearing impairment contributes additionally to deficits in vocal emotion recognition, separate from deficits related to age. These effects of age and hearing loss appear to be quite robust, being evident in reduced accuracy scores and d' measures, as well as in reaction time measures. ACKNOWLEDGMENTS: This research was funded by National Institutes of Health (NIH) Grant R01 DC014233, the Clinical Management Core of NIH Grant P20 GM10923 and the Human Research Subject Core of P30 DC004662. Portions of this study were presented at the Midwinter Meeting of the Association for Research in Otolaryngology held in San Diego, CA on February 9–14, 2018. The authors have no conflicts of interest to disclose. Address for correspondence: Monita Chatterjee, Auditory Prostheses and Perception Lab, Boys Town National Research Hospital, 425 N 30th St, Omaha, NE 68131, USA. E-mail: monita.chatterjee@boystown.org Received April 18, 2018; accepted November 20, 2018. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.
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Regulation of somatostatin receptor 2 by proinflammatory, microbial and obesity-related signals in periodontal cells and tissues
Periodontitis is a chronic disease characterized by a progressive and irreversible destruction of the tooth-supporting tissues, including gingiva and periodontal ligament (PDL). Microorganisms, such as Fusobacter...
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Regulation of somatostatin receptor 2 by proinflammatory, microbial and obesity-related signals in periodontal cells and tissues
Periodontitis is a chronic disease characterized by a progressive and irreversible destruction of the tooth-supporting tissues, including gingiva and periodontal ligament (PDL). Microorganisms, such as Fusobacter...
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Longitudinal tau and metabolic PET imaging in relation to novel CSF tau measures in Alzheimer’s disease
Abstract
Purpose
Studies comparing CSF and PET tau biomarkers have included only commercial CSF assays examining specific phosphorylation sites (e.g. threonine 181, P-tau181p) and mid-domain tau (i.e. total tau, T-tau). Moreover, these studies did not examine CSF tau levels in relation to cerebral glucose metabolism. We thus aimed to examine CSF tau measures, using both commercial and novel assays, in relation to [18F]THK5317 (tau) and [18F]FDG PET (glucose metabolism).
Methods
Fourteen Alzheimer's disease (AD) patients (seven prodromal, seven dementia) underwent [18F]THK5317 and [18F]FDG PET studies, with follow-up performed in ten subjects (six prodromal, four dementia) after 17 months. In addition to commercial assays, novel measures capturing N-terminus+mid-domain (tau N-Mid) and C-terminally truncated (tau-368) fragments were included.
Results
While the levels of all forms of CSF tau were found to be inversely associated with baseline [18F]FDG uptake, associations with baseline [18F]THK5317 uptake varied in relation to the degree of isocortical hypometabolism ([18F]FDG SUVR). Changes in the levels of the novel CSF markers tracked longitudinal changes in tracer uptake better than changes in P-tau181p and T-tau levels, and improved concordance with dichotomized regional [18F]THK5317 measures.
Conclusion
Our findings suggest that neurodegeneration may modulate the relationship between CSF and PET tau biomarkers, and that, by comparison to P-tau181p and T-tau, tau-368 and tau N-Mid may better capture tau pathology and synaptic impairment.
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Longitudinal tau and metabolic PET imaging in relation to novel CSF tau measures in Alzheimer’s disease
Abstract
Purpose
Studies comparing CSF and PET tau biomarkers have included only commercial CSF assays examining specific phosphorylation sites (e.g. threonine 181, P-tau181p) and mid-domain tau (i.e. total tau, T-tau). Moreover, these studies did not examine CSF tau levels in relation to cerebral glucose metabolism. We thus aimed to examine CSF tau measures, using both commercial and novel assays, in relation to [18F]THK5317 (tau) and [18F]FDG PET (glucose metabolism).
Methods
Fourteen Alzheimer's disease (AD) patients (seven prodromal, seven dementia) underwent [18F]THK5317 and [18F]FDG PET studies, with follow-up performed in ten subjects (six prodromal, four dementia) after 17 months. In addition to commercial assays, novel measures capturing N-terminus+mid-domain (tau N-Mid) and C-terminally truncated (tau-368) fragments were included.
Results
While the levels of all forms of CSF tau were found to be inversely associated with baseline [18F]FDG uptake, associations with baseline [18F]THK5317 uptake varied in relation to the degree of isocortical hypometabolism ([18F]FDG SUVR). Changes in the levels of the novel CSF markers tracked longitudinal changes in tracer uptake better than changes in P-tau181p and T-tau levels, and improved concordance with dichotomized regional [18F]THK5317 measures.
Conclusion
Our findings suggest that neurodegeneration may modulate the relationship between CSF and PET tau biomarkers, and that, by comparison to P-tau181p and T-tau, tau-368 and tau N-Mid may better capture tau pathology and synaptic impairment.
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1 in 10 American adults have food allergies, but nearly twice as many think they do
Many adults mistake other food-related conditions for allergies. (Source: ABC News: Health)
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1 in 10 American adults have food allergies, but nearly twice as many think they do
Many adults mistake other food-related conditions for allergies. (Source: ABC News: Health)
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1 in 10 American adults have food allergies, but nearly twice as many think they do
Many adults mistake other food-related conditions for allergies. (Source: ABC News: Health)
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1 in 10 American adults have food allergies, but nearly twice as many think they do
Many adults mistake other food-related conditions for allergies. (Source: ABC News: Health)
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Factivity and subject extraction in Jordanian Arabic
Publication date: Available online 3 January 2019Source: LinguaAuthor(s): Marwan JarrahAbstractThis paper investigates subject extraction from embedded clauses in Jordanian Arabic (JA). Firstly, it shows that JA maintains the division between factive vs. non-factive verbs with respect to (subject) extraction. We argue that non-factive clausal complements are not islands for extraction, and, hence, their subject can undergo movement to the left periphery of the main clause. We use Starke's (2001) proposal of Relativized Minimality to account for the ensuing restriction that bans the object and/or locative adjuncts of the factive clausal complement to appear pre-verbally (while the subject is extracted). We propose that this restriction is due to the richly-featured content of the subject wh...
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Vocal Fatigue —Do Young Speech-Language Pathologists Practice What They Preach?
Speech-Language Pathologists can be categorized as Level II professional voice users who play the roles of voice therapist or vocal coach to treat voice problems. SLPs may be at the risk of experiencing vocal fatigue due to vocal loading and other contributing factors. The present study was undertaken to find the percentage of SLPs reporting vocal fatigue, the probable factors resulting in vocal fatigue, the measures that are taken to avoid/reduce the occurrence of vocal fatigue, its effect on their professional and personal life and the measures taken to tackle it. (Source: Journal of Voice)
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Factivity and subject extraction in Jordanian Arabic
Publication date: Available online 3 January 2019Source: LinguaAuthor(s): Marwan JarrahAbstractThis paper investigates subject extraction from embedded clauses in Jordanian Arabic (JA). Firstly, it shows that JA maintains the division between factive vs. non-factive verbs with respect to (subject) extraction. We argue that non-factive clausal complements are not islands for extraction, and, hence, their subject can undergo movement to the left periphery of the main clause. We use Starke's (2001) proposal of Relativized Minimality to account for the ensuing restriction that bans the object and/or locative adjuncts of the factive clausal complement to appear pre-verbally (while the subject is extracted). We propose that this restriction is due to the richly-featured content of the subject wh...
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Vocal Fatigue —Do Young Speech-Language Pathologists Practice What They Preach?
Speech-Language Pathologists can be categorized as Level II professional voice users who play the roles of voice therapist or vocal coach to treat voice problems. SLPs may be at the risk of experiencing vocal fatigue due to vocal loading and other contributing factors. The present study was undertaken to find the percentage of SLPs reporting vocal fatigue, the probable factors resulting in vocal fatigue, the measures that are taken to avoid/reduce the occurrence of vocal fatigue, its effect on their professional and personal life and the measures taken to tackle it. (Source: Journal of Voice)
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Hearing Loss Linked to Dementia, Other Health Issues
The New York Times recently reported on several studies indicating a relationship between untreated hearing loss and other heath issues. The article also questions why most health insurance companies—including Medicare—do not typically cover hearing aids when studies show that health care costs are much higher when hearing loss goes uncorrected. Related health care risks found in these and other studies include dementia, depression, injuries resulting from balance issues, and cardiovascular diseases. The two studies showed increased risk for medical comorbidities and higher health care cost data for people with untreated hearing loss. One study demonstrated a 50-percent increased risk in dementia for those with hearing loss and a 40-percent increased risk of depression. The seco...
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Hundreds more children and adults eligible for cochlear implants on the NHS
Hundreds more people with severe to profound deafness are expected to be eligible for cochlear implants each year, due to updated NICE guidance. (Source: NHS Networks)
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Hundreds more children and adults eligible for cochlear implants on the NHS
Hundreds more people with severe to profound deafness are expected to be eligible for cochlear implants each year, due to updated NICE guidance. (Source: NHS Networks)
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Hundreds more children and adults eligible for cochlear implants on the NHS
Hundreds more people with severe to profound deafness are expected to be eligible for cochlear implants each year, due to updated NICE guidance. (Source: NHS Networks)
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Hundreds more children and adults eligible for cochlear implants on the NHS
Hundreds more people with severe to profound deafness are expected to be eligible for cochlear implants each year, due to updated NICE guidance. (Source: NHS Networks)
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Hearing Loss Linked to Dementia, Other Health Issues
The New York Times recently reported on several studies indicating a relationship between untreated hearing loss and other heath issues. The article also questions why most health insurance companies—including Medicare—do not typically cover hearing aids when studies show that health care costs are much higher when hearing loss goes uncorrected. Related health care risks found in these and other studies include dementia, depression, injuries resulting from balance issues, and cardiovascular diseases. The two studies showed increased risk for medical comorbidities and higher health care cost data for people with untreated hearing loss. One study demonstrated a 50-percent increased risk in dementia for those with hearing loss and a 40-percent increased risk of depression. The seco...
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Hearing Loss Linked to Dementia, Other Health Issues
The New York Times recently reported on several studies indicating a relationship between untreated hearing loss and other heath issues. The article also questions why most health insurance companies—including Medicare—do not typically cover hearing aids when studies show that health care costs are much higher when hearing loss goes uncorrected. Related health care risks found in these and other studies include dementia, depression, injuries resulting from balance issues, and cardiovascular diseases. The two studies showed increased risk for medical comorbidities and higher health care cost data for people with untreated hearing loss. One study demonstrated a 50-percent increased risk in dementia for those with hearing loss and a 40-percent increased risk of depression. The seco...
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Nearly Half Of Food Allergies Are Developed In Adulthood
BOSTON (CBS) — Christine Collins carries her EpiPen wherever she goes. After eating seafood her entire life, the 42-year-old developed a life-threatening food allergy to shellfish in her 20s. "It felt like my throat was closing up like, started with wheezing and just got tighter and tighter," she said. "By the time we were in front of the ER, I couldn't breathe so that's how fast it happened." An EpiPen and a medical alert bracelet (WBZ-TV) New research shows an estimated 26 million adults have a food allergy in the U.S. — that is one in 10 adults. Nearly half developed at least one of their allergies in adulthood like Christine. Dr. Wayne Shreffler, the director of the Food Allergy Center at Massachusetts General Hospital, said, "It c...
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Do You Think You Have A Food Allergy? New Study Says There Is A 50% Chance You Don't
A new study has revealed some surprising new information about food allergies in the U.S. (Source: Forbes.com Healthcare News)
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How common are food allergies?
(JAMA Network) Survey data suggest at least one in 10 US adults are food allergic and nearly one in five believe they have a food allergy. Food allergies are expensive and potentially life-threatening conditions. In this nationally representative survey study of more than 40,000 US adults, nearly half of food-allergic adults developed allergies during adulthood, many reported being allergic to multiple foods, and 38 percent reported at least one food allergy-related emergency department visit in their lifetime. (Source: EurekAlert! - Medicine and Health)
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Do You Think You Have A Food Allergy? New Study Says There Is A 50% Chance You Don't
A new study has revealed some surprising new information about food allergies in the U.S. (Source: Forbes.com Healthcare News)
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How common are food allergies?
(JAMA Network) Survey data suggest at least one in 10 US adults are food allergic and nearly one in five believe they have a food allergy. Food allergies are expensive and potentially life-threatening conditions. In this nationally representative survey study of more than 40,000 US adults, nearly half of food-allergic adults developed allergies during adulthood, many reported being allergic to multiple foods, and 38 percent reported at least one food allergy-related emergency department visit in their lifetime. (Source: EurekAlert! - Medicine and Health)
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Bristol-Myers Squibb to Acquire Celgene to Create a Premier Innovative Biopharma Company
Highly Complementary Portfolios with Leading Franchises in Oncology, Immunology and Inflammation and Cardiovascular Disease Significantly Expands Phase III Assets with Six Expected Near-Term Product Launches, Representing Greater Than $15 Billion in Rev... Biopharmaceuticals, Mergers & Acquisitions Bristol-Myers Squibb, Celgene (Source: HSMN NewsFeed)
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Electroacoustic Stimulation
Electric acoustic stimulation (EAS), also known as hybrid stimulation, is indicated for individuals with intact low-frequency hearing and profound high-frequency hearing loss. Although low frequencies contribute to speech perception, these individuals are usually only able to detect vowels, but few or no consonants, and thus have difficulty with word understanding and hearing in noise. EAS uses the cochlear implant electrode array to stimulate the high frequencies within the basal turn of the cochlea coupled with a hearing aid to convey the low frequencies at the apical turn in the same ear. (Source: Otolaryngologic clinics of North America)
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Osseointegrated Auditory Devices
Osseointegrated auditory devices (OADs) are hearing devices that use an external receiver/processor that stimulates bone conduction of sound via a titanium prosthesis that is drilled into the bone of the cranium. Since their introduction in 1977, OADs have undergone substantial evolution, including changes in manufacturing of the implant, improvements in the external sound processor, and simplification of implantation techniques. Expansion of criteria for patient candidacy for implantation has occurred corresponding with changes in the implants and processors. (Source: Otolaryngologic clinics of North America)
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Extended-Wear Hearing Technology
A new category of hearing technology has emerged that comprises devices inserted deep into the ear canal. Although not implanted, they represent an extension of what is expected of a traditional hearing aid. There are advantages to these devices, but they are not suited for all individuals with hearing loss. This category consists of 2 devices currently available in the United States: Lyric (Phonak AG, Stafa, Switzerland) and Earlens (Earlens, Menlo Park, CA, USA). (Source: Otolaryngologic clinics of North America)
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Limitations of Conventional Hearing Aids
This article examines and evaluates methods, from an audiologist 's perspective, of reducing common complaints with conventional hearing aids and issues such as the occlusion effect, acoustic feedback, discomfort, and insufficient gain. Although often successful, reducing one problem may have the tradeoff of causing another issue. This article is meant to provi de information to the reader regarding modern conventional hearing aids, the means to alleviate common problems in the clinic, and when middle ear implants and osseointegrated implants can be beneficial. (Source: Otolaryngologic clinics of North America)
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Osseointegrated Auditory Devices
Bonebridge is an active bone conduction device that consists of a bone conduction-floating mass transducer (BC-FMT) and magnet internally and an audio processor externally. Surgery for implantation can be performed under local anesthesia but requires surgical planning for adequate bone depth for the BC-FMT well. Bonebridge does not require osseointegration to function, so the device can be activated early. One disadvantage of Bonebridge is the sizable artifact on MRI created by the internal magnet. Studies of Bonebridge implantation demonstrate few complications, and hearing outcomes are audiologically equivalent to other bone conduction devices. (Source: Otolaryngologic clinics of North America)
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The Vibrant Soundbridge
This article reviews the author 's experience and the international uses of this versatile device. (Source: Otolaryngologic clinics of North America)
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Do You Think You Have A Food Allergy? New Study Says There Is A 50% Chance You Don't
A new study has revealed some surprising new information about food allergies in the U.S. (Source: Forbes.com Healthcare News)
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Bristol-Myers Squibb to Acquire Celgene to Create a Premier Innovative Biopharma Company
Highly Complementary Portfolios with Leading Franchises in Oncology, Immunology and Inflammation and Cardiovascular Disease Significantly Expands Phase III Assets with Six Expected Near-Term Product Launches, Representing Greater Than $15 Billion in Rev... Biopharmaceuticals, Mergers & Acquisitions Bristol-Myers Squibb, Celgene (Source: HSMN NewsFeed)
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Parent Experiences with Paediatric Allergy Pathways in the West Midlands: A Qualitative study
Abstract
Background
The prevalence, severity and complexity of allergic diseases has been increasing steadily in the UK over the last few decades. Primary care physicians are often not adequately trained in allergy management whilst specialist services for allergy are scarce and heterogeneous. Services, therefore, have been unable to meet the rising demand. This is particularly true for paediatric allergy services in the UK.
Objective
To understand parent experiences with paediatric allergy pathways in the West Midlands (WM) region of the UK.
Methods
Parents of children aged between 0‐16 years from the WM region were recruited opportunistically until thematic saturation was achieved. 18 semi‐structured interviews were carried out and transcribed verbatim. Data were analysed on NVivo software using the framework method. Themes were identified from the transcripts as well as from existing literature.
Results
Parents highlighted numerous issues related to allergy services in the region including difficulties with being taken seriously by their physicians, problems with accessing healthcare and issues with information and the need for additional supportive care for allergies.
Conclusions and Clinical relevance
Primary care for children with allergies in the West Midlands is disparate. Parents experience difficulties in accessing primary and secondary care services and also obtaining timely and appropriate information regarding their child's allergies. Most parents were happy to be reviewed by either specialist nurses or by consultants in the hospital. Improving accessibility and availability of reliable information as well as provision of additional services (such as psychologists and dietetics) were highlighted by parents as being important to allergy services in the region. These findings can help inform future planning and commissioning of allergy services.
This article is protected by copyright. All rights reserved.
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Electroacoustic Stimulation
Electric acoustic stimulation (EAS), also known as hybrid stimulation, is indicated for individuals with intact low-frequency hearing and profound high-frequency hearing loss. Although low frequencies contribute to speech perception, these individuals are usually only able to detect vowels, but few or no consonants, and thus have difficulty with word understanding and hearing in noise. EAS uses the cochlear implant electrode array to stimulate the high frequencies within the basal turn of the cochlea coupled with a hearing aid to convey the low frequencies at the apical turn in the same ear. (Source: Otolaryngologic clinics of North America)
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Osseointegrated Auditory Devices
Osseointegrated auditory devices (OADs) are hearing devices that use an external receiver/processor that stimulates bone conduction of sound via a titanium prosthesis that is drilled into the bone of the cranium. Since their introduction in 1977, OADs have undergone substantial evolution, including changes in manufacturing of the implant, improvements in the external sound processor, and simplification of implantation techniques. Expansion of criteria for patient candidacy for implantation has occurred corresponding with changes in the implants and processors. (Source: Otolaryngologic clinics of North America)
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Physiology of Osseointegration
"Bone conduction implant devices rely on osseointegration of titanium implants with the underlying skull, characterized by endosseous healing and de-novo bone formation both surrounding and onto the implant surface. The key steps in osseointegration are the initial tissue response to implantation, peri-implant osteogenesis, and peri-implant bone remodeling. There is increasing evidence that osseointegration is primarily an immune-mediated process with the key players being the complement cascade and macrophages, which form part of the host innate immunity. Implant design and composition, pat ient systemic factors, surgical technique, and loading characteristics can all affect the success of osseointegration." (Source: Otolaryngologic clinics of North America)
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Extended-Wear Hearing Technology
A new category of hearing technology has emerged that comprises devices inserted deep into the ear canal. Although not implanted, they represent an extension of what is expected of a traditional hearing aid. There are advantages to these devices, but they are not suited for all individuals with hearing loss. This category consists of 2 devices currently available in the United States: Lyric (Phonak AG, Stafa, Switzerland) and Earlens (Earlens, Menlo Park, CA, USA). (Source: Otolaryngologic clinics of North America)
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Limitations of Conventional Hearing Aids
This article examines and evaluates methods, from an audiologist 's perspective, of reducing common complaints with conventional hearing aids and issues such as the occlusion effect, acoustic feedback, discomfort, and insufficient gain. Although often successful, reducing one problem may have the tradeoff of causing another issue. This article is meant to provi de information to the reader regarding modern conventional hearing aids, the means to alleviate common problems in the clinic, and when middle ear implants and osseointegrated implants can be beneficial. (Source: Otolaryngologic clinics of North America)
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Osseointegrated Auditory Devices
Bonebridge is an active bone conduction device that consists of a bone conduction-floating mass transducer (BC-FMT) and magnet internally and an audio processor externally. Surgery for implantation can be performed under local anesthesia but requires surgical planning for adequate bone depth for the BC-FMT well. Bonebridge does not require osseointegration to function, so the device can be activated early. One disadvantage of Bonebridge is the sizable artifact on MRI created by the internal magnet. Studies of Bonebridge implantation demonstrate few complications, and hearing outcomes are audiologically equivalent to other bone conduction devices. (Source: Otolaryngologic clinics of North America)
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Nearly Half Of Food Allergies Are Developed In Adulthood
BOSTON (CBS) — Christine Collins carries her EpiPen wherever she goes. After eating seafood her entire life, the 42-year-old developed a life-threatening food allergy to shellfish in her 20s. "It felt like my throat was closing up like, started with wheezing and just got tighter and tighter," she said. "By the time we were in front of the ER, I couldn't breathe so that's how fast it happened." An EpiPen and a medical alert bracelet (WBZ-TV) New research shows an estimated 26 million adults have a food allergy in the U.S. — that is one in 10 adults. Nearly half developed at least one of their allergies in adulthood like Christine. Dr. Wayne Shreffler, the director of the Food Allergy Center at Massachusetts General Hospital, said, "It c...
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Do You Think You Have A Food Allergy? New Study Says There Is A 50% Chance You Don't
A new study has revealed some surprising new information about food allergies in the U.S. (Source: Forbes.com Healthcare News)
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How common are food allergies?
(JAMA Network) Survey data suggest at least one in 10 US adults are food allergic and nearly one in five believe they have a food allergy. Food allergies are expensive and potentially life-threatening conditions. In this nationally representative survey study of more than 40,000 US adults, nearly half of food-allergic adults developed allergies during adulthood, many reported being allergic to multiple foods, and 38 percent reported at least one food allergy-related emergency department visit in their lifetime. (Source: EurekAlert! - Medicine and Health)
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Bristol-Myers Squibb to Acquire Celgene to Create a Premier Innovative Biopharma Company
Highly Complementary Portfolios with Leading Franchises in Oncology, Immunology and Inflammation and Cardiovascular Disease Significantly Expands Phase III Assets with Six Expected Near-Term Product Launches, Representing Greater Than $15 Billion in Rev... Biopharmaceuticals, Mergers & Acquisitions Bristol-Myers Squibb, Celgene (Source: HSMN NewsFeed)
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Parent Experiences with Paediatric Allergy Pathways in the West Midlands: A Qualitative study
Abstract
Background
The prevalence, severity and complexity of allergic diseases has been increasing steadily in the UK over the last few decades. Primary care physicians are often not adequately trained in allergy management whilst specialist services for allergy are scarce and heterogeneous. Services, therefore, have been unable to meet the rising demand. This is particularly true for paediatric allergy services in the UK.
Objective
To understand parent experiences with paediatric allergy pathways in the West Midlands (WM) region of the UK.
Methods
Parents of children aged between 0‐16 years from the WM region were recruited opportunistically until thematic saturation was achieved. 18 semi‐structured interviews were carried out and transcribed verbatim. Data were analysed on NVivo software using the framework method. Themes were identified from the transcripts as well as from existing literature.
Results
Parents highlighted numerous issues related to allergy services in the region including difficulties with being taken seriously by their physicians, problems with accessing healthcare and issues with information and the need for additional supportive care for allergies.
Conclusions and Clinical relevance
Primary care for children with allergies in the West Midlands is disparate. Parents experience difficulties in accessing primary and secondary care services and also obtaining timely and appropriate information regarding their child's allergies. Most parents were happy to be reviewed by either specialist nurses or by consultants in the hospital. Improving accessibility and availability of reliable information as well as provision of additional services (such as psychologists and dietetics) were highlighted by parents as being important to allergy services in the region. These findings can help inform future planning and commissioning of allergy services.
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Table of contents
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Table of contents
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2FdNV6N
EBV-positive mucocutaneous ulcer mimicking a peri-implantitis in a patient with systemic lupus erythematosus
The Epstein–Barr virus (EBV)-positive mucocutaneous ulcer (EBVMCU) is a lymphoproliferative disorder, characterized clinically by cutaneous and/or mucosal ulcers in patients receiving immunosuppressive drugs, most commonly methotrexate and azathioprine, or in elderly, probably because of age-related immunosenescence. It was firstly described in 2010 by Dojcinov et al.1 and listed as a distinctive clinicopathological entity in the recent 2017 World Health Organization (WHO) classification of lymphoid neoplasms.
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Quality of Life and Behavioural Assessment in Post-adenotonsillectomy Cases of Paediatric Age Group
This study demonstrates significant score changes across all questionnaire domains, comparing pre and post operative data indicating an improvement in their quality of life and behaviour. Hence, we advocate that adenotonsillectomy may be considered as an effective treatment in properly selected patients with OSAS. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2CQzUKs
EBV-positive mucocutaneous ulcer mimicking a peri-implantitis in a patient with systemic lupus erythematosus
The Epstein–Barr virus (EBV)-positive mucocutaneous ulcer (EBVMCU) is a lymphoproliferative disorder, characterized clinically by cutaneous and/or mucosal ulcers in patients receiving immunosuppressive drugs, most commonly methotrexate and azathioprine, or in elderly, probably because of age-related immunosenescence. It was firstly described in 2010 by Dojcinov et al.1 and listed as a distinctive clinicopathological entity in the recent 2017 World Health Organization (WHO) classification of lymphoid neoplasms.
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Pre-clinical compartmental pharmacokinetic modeling of 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) as a photosensitizer in rat plasma by validated HPLC method
Photochem. Photobiol. Sci., 2019, Advance Article
DOI: 10.1039/C8PP00339D, Paper
DOI: 10.1039/C8PP00339D, Paper
Kowthavarapu Venkata Krishna, Ranendra Narayana Saha, Anu Puri, Mathias Viard, Bruce A. Shapiro, Sunil Kumar Dubey
A second-generation photosensitizer, 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) has shown therapeutic potential in the treatment of esophageal cancer.
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The content of this RSS Feed (c) The Royal Society of Chemistry
A second-generation photosensitizer, 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) has shown therapeutic potential in the treatment of esophageal cancer.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
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Such similatives: a cross-linguistic reconnaissance
Publication date: Available online 3 January 2019Source: Language SciencesAuthor(s): Johan van der Auwera, Kalyanamalini SahooAbstractThis paper is a preliminary exploration of the semantic and formal properties of the English word such and some of its counterparts in other languages. The proposal is that such words are 'demonstrative similatives' (or, equivalently, 'similative demonstratives'), i.e., their meanings lie at the intersection of the semantic dimensions of similarity and demonstration. We show that this kind of classification is straightforward for languages like Latin and Sanskrit, in which the counterparts to such occur in both similative and demonstrative paradigms. In these so-called 'correlative' paradigms the demonstrative similatives occur in systems with bo...
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Evidential strategies in receiver-directed talk: The case of English inferential adverbs
This study demonstrates that clearly and obviously are used to express inference, conjecture, assumption and self-evidence. The four notions can be organised on a cline, each showing a different degree of (inter)subjectivity, which is why this study argues that (inter)subjectification is responsible not only for their development from adverbs of manner into evidential adverbs (which is generally agreed on), but also for the different types of evidential meaning they express. It also argues that self-evidence is a post-evidential meaning of the two adverbs. This paper demonstrates that inferences, conjectures and assumptions function as strategies for eliciting a response from the addressee. Inferences and assumptions serve as prompts; conjectures have a challenging function. Inferences are...
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A service perspective on 'Evidence based pathways to intervention for children with Language Disorders'.
Authors: Parsons S PMID: 30600601 [PubMed - in process] (Source: International Journal of Language and Communication Disorders)
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Photosynthetically-active radiation, UV-A and UV-B, causes both common and specific damage and photoprotective responses in the model liverwort Marchantia polymorpha subsp. ruderalis
Photochem. Photobiol. Sci., 2019, Advance Article
DOI: 10.1039/C8PP00421H, Paper
DOI: 10.1039/C8PP00421H, Paper
Gonzalo Soriano, María-Ángeles Del-Castillo-Alonso, Laura Monforte, Rafael Tomás-Las-Heras, Javier Martínez-Abaigar, Encarnación Núñez-Olivera
Damage caused by high PAR and UV-B was balanced by protection mechanisms induced by the same radiations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Damage caused by high PAR and UV-B was balanced by protection mechanisms induced by the same radiations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://rsc.li/2F7KvTJ
Such similatives: a cross-linguistic reconnaissance
Publication date: Available online 3 January 2019Source: Language SciencesAuthor(s): Johan van der Auwera, Kalyanamalini SahooAbstractThis paper is a preliminary exploration of the semantic and formal properties of the English word such and some of its counterparts in other languages. The proposal is that such words are 'demonstrative similatives' (or, equivalently, 'similative demonstratives'), i.e., their meanings lie at the intersection of the semantic dimensions of similarity and demonstration. We show that this kind of classification is straightforward for languages like Latin and Sanskrit, in which the counterparts to such occur in both similative and demonstrative paradigms. In these so-called 'correlative' paradigms the demonstrative similatives occur in systems with bo...
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Faqtaf
Evidential strategies in receiver-directed talk: The case of English inferential adverbs
This study demonstrates that clearly and obviously are used to express inference, conjecture, assumption and self-evidence. The four notions can be organised on a cline, each showing a different degree of (inter)subjectivity, which is why this study argues that (inter)subjectification is responsible not only for their development from adverbs of manner into evidential adverbs (which is generally agreed on), but also for the different types of evidential meaning they express. It also argues that self-evidence is a post-evidential meaning of the two adverbs. This paper demonstrates that inferences, conjectures and assumptions function as strategies for eliciting a response from the addressee. Inferences and assumptions serve as prompts; conjectures have a challenging function. Inferences are...
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A service perspective on 'Evidence based pathways to intervention for children with Language Disorders'.
Authors: Parsons S PMID: 30600601 [PubMed - in process] (Source: International Journal of Language and Communication Disorders)
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High rate of food allergies seen in U.S. adults
(Reuters Health) - More than 10 percent of American adults are allergic to at least one food, a new study suggests. (Source: Reuters: Health)
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Half Adults Who Claim Food Allergy Don't Have One
Experts said the findings highlight two important facts: Food allergies are common among U.S. adults, and many mistakenly believe they have one. (Source: WebMD Health)
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1 in 10 Adults Have Food Allergies, But Twice as Many Think They Do
FRIDAY, Jan. 4, 2019 -- More than 10 percent of U.S. adults have a food allergy -- and nearly double that believe they do, a new study estimates. Researchers found that 19 percent of those surveyed thought they had a food allergy. But when the... (Source: Drugs.com - Daily MedNews)
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Comparison of micro-CT and histomorphometry in the measurement of bone-implant contact ratios
The purpose of this study was to measure the three dimensional bone-to-implant contact (BIC) ratios calculated with an associated software algorithm on 3D micro-computed tomography (μCT) scans and compare them to measurements made on the basis of two-dimensional histomorphometry.
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An Aspirin a Day May Help Ease Acute Exacerbations of COPD (CME/CE)
(MedPage Today) -- Treatment also reduced dyspnea and improved quality of life (Source: MedPage Today Allergy)
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Daily Aspirin May Reduce COPD Exacerbations
(MedPage Today) -- Treatment also appeared to improve shortness of breath (Source: MedPage Today Allergy)
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High rate of food allergies seen in U.S. adults
(Reuters Health) - More than 10 percent of American adults are allergic to at least one food, a new study suggests. (Source: Reuters: Health)
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Half Adults Who Claim Food Allergy Don't Have One
Experts said the findings highlight two important facts: Food allergies are common among U.S. adults, and many mistakenly believe they have one. (Source: WebMD Health)
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1 in 10 Adults Have Food Allergies, But Twice as Many Think They Do
FRIDAY, Jan. 4, 2019 -- More than 10 percent of U.S. adults have a food allergy -- and nearly double that believe they do, a new study estimates. Researchers found that 19 percent of those surveyed thought they had a food allergy. But when the... (Source: Drugs.com - Daily MedNews)
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Comparison of micro-CT and histomorphometry in the measurement of bone-implant contact ratios
The purpose of this study was to measure the three dimensional bone-to-implant contact (BIC) ratios calculated with an associated software algorithm on 3D micro-computed tomography (μCT) scans and compare them to measurements made on the basis of two-dimensional histomorphometry.
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An Aspirin a Day May Help Ease Acute Exacerbations of COPD (CME/CE)
(MedPage Today) -- Treatment also reduced dyspnea and improved quality of life (Source: MedPage Today Allergy)
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Daily Aspirin May Reduce COPD Exacerbations
(MedPage Today) -- Treatment also appeared to improve shortness of breath (Source: MedPage Today Allergy)
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High rate of food allergies seen in U.S. adults
(Reuters Health) - More than 10 percent of American adults are allergic to at least one food, a new study suggests. (Source: Reuters: Health)
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1 in 10 Adults Have Food Allergies, But Twice as Many Think They Do
FRIDAY, Jan. 4, 2019 -- More than 10 percent of U.S. adults have a food allergy -- and nearly double that believe they do, a new study estimates. Researchers found that 19 percent of those surveyed thought they had a food allergy. But when the... (Source: Drugs.com - Daily MedNews)
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High rate of food allergies seen in U.S. adults
(Reuters Health) - More than 10 percent of American adults are allergic to at least one food, a new study suggests. (Source: Reuters: Health)
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Half Adults Who Claim Food Allergy Don't Have One
Experts said the findings highlight two important facts: Food allergies are common among U.S. adults, and many mistakenly believe they have one. (Source: WebMD Health)
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1 in 10 Adults Have Food Allergies, But Twice as Many Think They Do
FRIDAY, Jan. 4, 2019 -- More than 10 percent of U.S. adults have a food allergy -- and nearly double that believe they do, a new study estimates. Researchers found that 19 percent of those surveyed thought they had a food allergy. But when the... (Source: Drugs.com - Daily MedNews)
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Patient compliance and mandible fractures: a prospective study
Fractures of the facial skeleton place a burden on healthcare systems at the individual and population level. It is suggested that a high proportion of such patients are non-compliant with various aspects of their care. It stands to reason that non-compliance would contribute to adverse outcomes and increased costs in general. The intent of this study was two-fold: to determine factors associated with poor compliance in the studied population of 215 patients with 359 mandible fractures, and to determine whether poor compliance is associated with an increased incidence of treatment complications. (Source: International Journal of Oral and Maxillofacial Surgery)
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Translational studies in patients with Autoinflammatory Diseases...from bedside to bench and back
Director's Seminar Series Dr. Goldbach-Mansky will present the work of her Laboratory of Clinical Immunology and Microbiology. Autoinflammatory diseases are a group of rare immune dysregulatory syndromes that present with unexplained fevers, rashes, joint pain, and inflammation in multiple organs, such as the central nervous system, the eyes, inner ears, bones, fat, blood vessels, lungs, and muscles. Many of the disease symptoms present very early in life, and patients do not have infections or malignacies. The discovery of single gene mutations, which modify the regulation of inflammatory pathways that are triggered by exogenous and endogenous " danger " molecules, has provided new concepts to understand this disease group. It also continues to provide us with new targets for intervention...
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Impact of surface contamination of implants with saliva during placement in augmented bone defects in sheep calvaria
Our aim was to try and find out whether contamination with saliva during insertion of dental implants affects osseointegration in bone that has been augmented with different grafts. Six bony defects were created in each of the calvaria of six sheep, and then augmented with three different materials (autogenous bone, bovine bone, and resorbable biphasic ceramic bone substitute) After five weeks of healing, three implants contaminated with saliva (contaminated group) and three not contaminated (uncontaminated group) were placed in the centre of the augmented areas. (Source: The British Journal of Oral and Maxillofacial Surgery)
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EBV-positive mucocutaneous ulcer mimicking a peri-implantitis in a patient with systemic lupus erythematosus
The Epstein–Barr virus (EBV)-positive mucocutaneous ulcer (EBVMCU) is a lymphoproliferative disorder, characterized clinically by cutaneous and/or mucosal ulcers in patients receiving immunosuppressive drugs, most commonly methotrexate and azathioprine, or in elderly, probably because of age-related immunosenescence. It was firstly described in 2010 by Dojcinov et al.1 and listed as a distinctive clinicopathological entity in the recent 2017 World Health Organization (WHO) classification of lymphoid neoplasms.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2GVsqdp
Impact of surface contamination of implants with saliva during placement in augmented bone defects in sheep calvaria
Our aim was to try and find out whether contamination with saliva during insertion of dental implants affects osseointegration in bone that has been augmented with different grafts. Six bony defects were created in each of the calvaria of six sheep, and then augmented with three different materials (autogenous bone, bovine bone, and resorbable biphasic ceramic bone substitute) After five weeks of healing, three implants contaminated with saliva (contaminated group) and three not contaminated (uncontaminated group) were placed in the centre of the augmented areas. (Source: The British Journal of Oral and Maxillofacial Surgery)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2TwtfL7
EBV-positive mucocutaneous ulcer mimicking a peri-implantitis in a patient with systemic lupus erythematosus
The Epstein–Barr virus (EBV)-positive mucocutaneous ulcer (EBVMCU) is a lymphoproliferative disorder, characterized clinically by cutaneous and/or mucosal ulcers in patients receiving immunosuppressive drugs, most commonly methotrexate and azathioprine, or in elderly, probably because of age-related immunosenescence. It was firstly described in 2010 by Dojcinov et al.1 and listed as a distinctive clinicopathological entity in the recent 2017 World Health Organization (WHO) classification of lymphoid neoplasms.
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The endoscopic endonasal approach for pediatric craniopharyngiomas
Craniopharyngiomas are rare but challenging tumors of the ventral skull base affecting primarily pediatric patients. In select cases, the endoscopic endonasal approach represents an appropriate surgical option when tumor resection is favored. However, nuances of the pediatric nasal corridor must be carefully considered to optimize both tumor resection and skull base reconstruction. Here we review pertinent developmental details, options for creation of an optimal endonasal corridor, principles of tumor resection, and techniques for reconstruction.
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Open Anterior Skull Base Surgery in the Pediatric Population: Anatomy, Approaches and Considerations
The objectives of this paper are to synthesize the existing literature on open approaches to the anterior skull base in children. First, we review the developmental anatomy of the anterior skull base. Next, we describe the most commonly used open approaches to the ASB and other adjunctive procedures. Lastly, we review the reconstructive options and comment important pediatric-specific considerations. Our review reports the variety of open approaches to access the anterior skull base in children.
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Special Considerations for Nasoseptal Flap Use in Children
The introduction of the vascularized pedicled nasoseptal flap has revolutionized endoscopic skull base surgery, providing a highly versatile option to repair even the most complex skull base defects. Though demonstrated with outstanding results in adult patients, there islimited experience in the pediatric population. Early investigation found that there are limitations in utilization of the nasoseptal flap in children due to craniofacial restrictions. More recently, these concerns have been mitigated, and nasoseptal flaps are reliably used in reconstructing even the largest skull base defects in the youngest patients.
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Locoregional Flaps in Pediatric Anterior Skull Base Surgery
Management of skull base defects involves the separation of the cranial cavity from the nasal cavity in order to prevent cerebrospinal fluid leak, pneumocephalus, and intracranial infection. The size and location of the defect as well as donor tissue available will determine the type of reconstruction. Reconstruction options include free tissue grafts, locoregional flaps and microvascular free flaps. In children, the size of potential flaps must be considered as well as the length of the pedicle, as often these differ in children.
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Introduction
Pediatric skull base pathology, though uncommon, is a unique challenge. While not common, for each patient and their family, it is a frightening diagnosis that is often difficult to understand. Even for many surgeons, these are rarely seen.
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Surgical Management of Juvenile Nasopharyngeal Angiofibroma
Juvenile Nasopharyngeal Angiofibromas (JNA) are benign yet aggressive anterior skull base tumors that occur almost exclusively in male adolescents. Diagnosis is typically made through radiographic findings and clinical characteristics; biopsy is not recommended due to the vascular nature of the disease. As with most tumors, there is a spectrum of tumor extent and invasion. In JNAs one of the most important components of extent is the vascular supply. Once the vascular supply is identified, a systematic approach to resection can be planned.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2C1uH0F
The endoscopic endonasal approach for pediatric craniopharyngiomas
Craniopharyngiomas are rare but challenging tumors of the ventral skull base affecting primarily pediatric patients. In select cases, the endoscopic endonasal approach represents an appropriate surgical option when tumor resection is favored. However, nuances of the pediatric nasal corridor must be carefully considered to optimize both tumor resection and skull base reconstruction. Here we review pertinent developmental details, options for creation of an optimal endonasal corridor, principles of tumor resection, and techniques for reconstruction.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2C1CKuF
Open Anterior Skull Base Surgery in the Pediatric Population: Anatomy, Approaches and Considerations
The objectives of this paper are to synthesize the existing literature on open approaches to the anterior skull base in children. First, we review the developmental anatomy of the anterior skull base. Next, we describe the most commonly used open approaches to the ASB and other adjunctive procedures. Lastly, we review the reconstructive options and comment important pediatric-specific considerations. Our review reports the variety of open approaches to access the anterior skull base in children.
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Pediatric Skull Base Surgery: Encephaloceles and Cerebrospinal Fluid Leaks
In recent years, endoscopic endonasal approaches (EEAs) to the pediatric skull base have become an increasingly popular method for treatment of a variety of malignant and benign lesions. These approaches have largely evolved from experience in adult patients and can be an excellent alternative to open procedures in carefully selected patients. Pediatric encephaloceles can be addressed via open craniotomy, transpalatal, and endoscopic endonasal methods. The surgical approach should be dictated by the anatomy of the patient as well as the size and location of the encephalocele in question.
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Special Considerations for Nasoseptal Flap Use in Children
The introduction of the vascularized pedicled nasoseptal flap has revolutionized endoscopic skull base surgery, providing a highly versatile option to repair even the most complex skull base defects. Though demonstrated with outstanding results in adult patients, there islimited experience in the pediatric population. Early investigation found that there are limitations in utilization of the nasoseptal flap in children due to craniofacial restrictions. More recently, these concerns have been mitigated, and nasoseptal flaps are reliably used in reconstructing even the largest skull base defects in the youngest patients.
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Locoregional Flaps in Pediatric Anterior Skull Base Surgery
Management of skull base defects involves the separation of the cranial cavity from the nasal cavity in order to prevent cerebrospinal fluid leak, pneumocephalus, and intracranial infection. The size and location of the defect as well as donor tissue available will determine the type of reconstruction. Reconstruction options include free tissue grafts, locoregional flaps and microvascular free flaps. In children, the size of potential flaps must be considered as well as the length of the pedicle, as often these differ in children.
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Introduction
Pediatric skull base pathology, though uncommon, is a unique challenge. While not common, for each patient and their family, it is a frightening diagnosis that is often difficult to understand. Even for many surgeons, these are rarely seen.
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Surgical Management of Juvenile Nasopharyngeal Angiofibroma
Juvenile Nasopharyngeal Angiofibromas (JNA) are benign yet aggressive anterior skull base tumors that occur almost exclusively in male adolescents. Diagnosis is typically made through radiographic findings and clinical characteristics; biopsy is not recommended due to the vascular nature of the disease. As with most tumors, there is a spectrum of tumor extent and invasion. In JNAs one of the most important components of extent is the vascular supply. Once the vascular supply is identified, a systematic approach to resection can be planned.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2C1uH0F
Patient compliance and mandible fractures: a prospective study
Fractures of the facial skeleton place a burden on healthcare systems at the individual and population level. It is suggested that a high proportion of such patients are non-compliant with various aspects of their care. It stands to reason that non-compliance would contribute to adverse outcomes and increased costs in general. The intent of this study was two-fold: to determine factors associated with poor compliance in the studied population of 215 patients with 359 mandible fractures, and to determine whether poor compliance is associated with an increased incidence of treatment complications.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Ttq7zo
Patient compliance and mandible fractures: a prospective study
Fractures of the facial skeleton place a burden on healthcare systems at the individual and population level. It is suggested that a high proportion of such patients are non-compliant with various aspects of their care. It stands to reason that non-compliance would contribute to adverse outcomes and increased costs in general. The intent of this study was two-fold: to determine factors associated with poor compliance in the studied population of 215 patients with 359 mandible fractures, and to determine whether poor compliance is associated with an increased incidence of treatment complications.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Ttq7zo
An Aspirin a Day May Help Ease Acute Exacerbations of COPD (CME/CE)
(MedPage Today) -- Treatment also reduced dyspnea and improved quality of life (Source: MedPage Today Allergy)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9gDh4
Study: Half of people who think they have allergies are wrong
When it comes to food allergies, Americans are more worried than they need to be, a new study says. (Source: Health News - UPI.com)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2LRRAZ1
The man who is allergic to BEER: 32-year-old suffers an anaphlyactic shock
The unnamed 32-year-old, believed to be from Coimbra, Portugal, was set to enjoy a Franziskaner beer (pictured) when he 'immediately' developed a tight throat and itchy lips. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9Tlru
An Aspirin a Day May Help Ease Acute Exacerbations of COPD (CME/CE)
(MedPage Today) -- Treatment also reduced dyspnea and improved quality of life (Source: MedPage Today Allergy)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9gDh4
Study: Half of people who think they have allergies are wrong
When it comes to food allergies, Americans are more worried than they need to be, a new study says. (Source: Health News - UPI.com)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2LRRAZ1
The man who is allergic to BEER: 32-year-old suffers an anaphlyactic shock
The unnamed 32-year-old, believed to be from Coimbra, Portugal, was set to enjoy a Franziskaner beer (pictured) when he 'immediately' developed a tight throat and itchy lips. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9Tlru
An Aspirin a Day May Help Ease Acute Exacerbations of COPD (CME/CE)
(MedPage Today) -- Treatment also reduced dyspnea and improved quality of life (Source: MedPage Today Allergy)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9gDh4
Study: Half of people who think they have allergies are wrong
When it comes to food allergies, Americans are more worried than they need to be, a new study says. (Source: Health News - UPI.com)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2LRRAZ1
The man who is allergic to BEER: 32-year-old suffers an anaphlyactic shock
The unnamed 32-year-old, believed to be from Coimbra, Portugal, was set to enjoy a Franziskaner beer (pictured) when he 'immediately' developed a tight throat and itchy lips. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9Tlru
An Aspirin a Day May Help Ease Acute Exacerbations of COPD (CME/CE)
(MedPage Today) -- Treatment also reduced dyspnea and improved quality of life (Source: MedPage Today Allergy)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9gDh4
Study: Half of people who think they have allergies are wrong
When it comes to food allergies, Americans are more worried than they need to be, a new study says. (Source: Health News - UPI.com)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2LRRAZ1
The man who is allergic to BEER: 32-year-old suffers an anaphlyactic shock
The unnamed 32-year-old, believed to be from Coimbra, Portugal, was set to enjoy a Franziskaner beer (pictured) when he 'immediately' developed a tight throat and itchy lips. (Source: the Mail online | Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s9Tlru
Impact of surface contamination of implants with saliva during placement in augmented bone defects in sheep calvaria
Our aim was to try and find out whether contamination with saliva during insertion of dental implants affects osseointegration in bone that has been augmented with different grafts. Six bony defects were created in each of the calvaria of six sheep, and then augmented with three different materials (autogenous bone, bovine bone, and resorbable biphasic ceramic bone substitute) After five weeks of healing, three implants contaminated with saliva (contaminated group) and three not contaminated (uncontaminated group) were placed in the centre of the augmented areas.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Qopmpi
Limitations of Conventional Hearing Aids
This article examines and evaluates methods, from an audiologist's perspective, of reducing common complaints with conventional hearing aids and issues such as the occlusion effect, acoustic feedback, discomfort, and insufficient gain. Although often successful, reducing one problem may have the tradeoff of causing another issue. This article is meant to provide information to the reader regarding modern conventional hearing aids, the means to alleviate common problems in the clinic, and when middle ear implants and osseointegrated implants can be beneficial.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SBBmGb
Extended-Wear Hearing Technology
A new category of hearing technology has emerged that comprises devices inserted deep into the ear canal. Although not implanted, they represent an extension of what is expected of a traditional hearing aid. There are advantages to these devices, but they are not suited for all individuals with hearing loss. This category consists of 2 devices currently available in the United States: Lyric (Phonak AG, Stafa, Switzerland) and Earlens (Earlens, Menlo Park, CA, USA).
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Auc0Dc
Osseointegrated Auditory Devices
Bonebridge is an active bone conduction device that consists of a bone conduction-floating mass transducer (BC-FMT) and magnet internally and an audio processor externally. Surgery for implantation can be performed under local anesthesia but requires surgical planning for adequate bone depth for the BC-FMT well. Bonebridge does not require osseointegration to function, so the device can be activated early. One disadvantage of Bonebridge is the sizable artifact on MRI created by the internal magnet. Studies of Bonebridge implantation demonstrate few complications, and hearing outcomes are audiologically equivalent to other bone conduction devices.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SAuSal
Physiology of Osseointegration
"Bone conduction implant devices rely on osseointegration of titanium implants with the underlying skull, characterized by endosseous healing and de-novo bone formation both surrounding and onto the implant surface. The key steps in osseointegration are the initial tissue response to implantation, peri-implant osteogenesis, and peri-implant bone remodeling. There is increasing evidence that osseointegration is primarily an immune-mediated process with the key players being the complement cascade and macrophages, which form part of the host innate immunity. Implant design and composition, patient systemic factors, surgical technique, and loading characteristics can all affect the success of osseointegration."
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Av23oS
The Vibrant Soundbridge
The Vibrant Soundbridge is a semi-implantable, active middle ear implant that is a safe and effective treatment for patients with sensorineural hearing loss. Since Food and Drug Administration approval for this indication, many international investigators have expanded its use for conductive and mixed hearing losses. This article reviews the author's experience and the international uses of this versatile device.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SxRVmh
Limitations of Conventional Hearing Aids
This article examines and evaluates methods, from an audiologist's perspective, of reducing common complaints with conventional hearing aids and issues such as the occlusion effect, acoustic feedback, discomfort, and insufficient gain. Although often successful, reducing one problem may have the tradeoff of causing another issue. This article is meant to provide information to the reader regarding modern conventional hearing aids, the means to alleviate common problems in the clinic, and when middle ear implants and osseointegrated implants can be beneficial.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SBBmGb
Extended-Wear Hearing Technology
A new category of hearing technology has emerged that comprises devices inserted deep into the ear canal. Although not implanted, they represent an extension of what is expected of a traditional hearing aid. There are advantages to these devices, but they are not suited for all individuals with hearing loss. This category consists of 2 devices currently available in the United States: Lyric (Phonak AG, Stafa, Switzerland) and Earlens (Earlens, Menlo Park, CA, USA).
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Auc0Dc
Osseointegrated Auditory Devices
Bonebridge is an active bone conduction device that consists of a bone conduction-floating mass transducer (BC-FMT) and magnet internally and an audio processor externally. Surgery for implantation can be performed under local anesthesia but requires surgical planning for adequate bone depth for the BC-FMT well. Bonebridge does not require osseointegration to function, so the device can be activated early. One disadvantage of Bonebridge is the sizable artifact on MRI created by the internal magnet. Studies of Bonebridge implantation demonstrate few complications, and hearing outcomes are audiologically equivalent to other bone conduction devices.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SAuSal
Physiology of Osseointegration
"Bone conduction implant devices rely on osseointegration of titanium implants with the underlying skull, characterized by endosseous healing and de-novo bone formation both surrounding and onto the implant surface. The key steps in osseointegration are the initial tissue response to implantation, peri-implant osteogenesis, and peri-implant bone remodeling. There is increasing evidence that osseointegration is primarily an immune-mediated process with the key players being the complement cascade and macrophages, which form part of the host innate immunity. Implant design and composition, patient systemic factors, surgical technique, and loading characteristics can all affect the success of osseointegration."
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Av23oS
The Vibrant Soundbridge
The Vibrant Soundbridge is a semi-implantable, active middle ear implant that is a safe and effective treatment for patients with sensorineural hearing loss. Since Food and Drug Administration approval for this indication, many international investigators have expanded its use for conductive and mixed hearing losses. This article reviews the author's experience and the international uses of this versatile device.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SxRVmh
Exploring in Silence: Hearing and Deaf Infants Explore Objects Differently Before Cochlear Implantation
Infant development has rarely been informed by the behavior of infants with sensory differences despite increasing recognition that infant behavior itself creates sensory learning opportunities. The purpose of this study of object exploration was to compare the behavior of hearing and deaf infants, with and without cochlear implants, in order to identify the effects of profound sensorineural hearing loss on infant exploration before cochlear implantation, the behavioral effects of access to auditory feedback after cochlear implantation, and the sensory motivation for exploration behaviors performed by hearing infants as well. The results showed that 9 ‐month‐old deaf infants explored objects as often as hearing infants but they used systematically different approaches and less variatio...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2AuusLV
Exploring in Silence: Hearing and Deaf Infants Explore Objects Differently Before Cochlear Implantation
Infant development has rarely been informed by the behavior of infants with sensory differences despite increasing recognition that infant behavior itself creates sensory learning opportunities. The purpose of this study of object exploration was to compare the behavior of hearing and deaf infants, with and without cochlear implants, in order to identify the effects of profound sensorineural hearing loss on infant exploration before cochlear implantation, the behavioral effects of access to auditory feedback after cochlear implantation, and the sensory motivation for exploration behaviors performed by hearing infants as well. The results showed that 9 ‐month‐old deaf infants explored objects as often as hearing infants but they used systematically different approaches and less variatio...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2AuusLV
Wear of direct resin composites and teeth: considerations for oral rehabilitation
Little is known about the wear rate of enamel and dentin opposing resin composite following restoration of the occlusal surface in patients with tooth wear. Hence, the aim of this in vitro study was to evaluate the wear of enamel and dentin surfaces when opposing each of three resin composites in a two‐body and three‐body wear test. The two‐body and three‐body wear of dentin, enamel, and three resin composites (Clearfil AP‐X, Filtek Z250, and Filtek Supreme) opposing four antagonists (stainless steel and three resin composites) were evaluated using the ACTA wear machine. In addition, all the surfaces were evaluated with scanning electron microscopy. The results showed the lowest wear rate in enamel and the highest in dentine, with the composite showing intermediate wear rates. The three‐body wear results were not affected by the antagonist and showed pure wear caused by the abrasive food medium. The in vitro enamel/composite wear ratio was 2.5. The results show that tooth wear accelerates as soon as enamel disappears and dentin is exposed to composite resin. Therefore, it is important to protect dentin with a restorative material.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s8Ur73
Wear of direct resin composites and teeth: considerations for oral rehabilitation
Little is known about the wear rate of enamel and dentin opposing resin composite following restoration of the occlusal surface in patients with tooth wear. Hence, the aim of this in vitro study was to evaluate the wear of enamel and dentin surfaces when opposing each of three resin composites in a two‐body and three‐body wear test. The two‐body and three‐body wear of dentin, enamel, and three resin composites (Clearfil AP‐X, Filtek Z250, and Filtek Supreme) opposing four antagonists (stainless steel and three resin composites) were evaluated using the ACTA wear machine. In addition, all the surfaces were evaluated with scanning electron microscopy. The results showed the lowest wear rate in enamel and the highest in dentine, with the composite showing intermediate wear rates. The three‐body wear results were not affected by the antagonist and showed pure wear caused by the abrasive food medium. The in vitro enamel/composite wear ratio was 2.5. The results show that tooth wear accelerates as soon as enamel disappears and dentin is exposed to composite resin. Therefore, it is important to protect dentin with a restorative material.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2s8Ur73
More than 1 in 10 US adults has a food allergy, study finds
Blake Sorensen of Chicago has a routine: "Phone, keys, wallet, EpiPen. That's what I've become accustomed to." (Source: CNN.com - Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SD3ZCO
More than 1 in 10 US adults has a food allergy, study finds
Blake Sorensen of Chicago has a routine: "Phone, keys, wallet, EpiPen. That's what I've become accustomed to." (Source: CNN.com - Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SD3ZCO
More than 1 in 10 US adults has a food allergy, study finds
Blake Sorensen of Chicago has a routine: "Phone, keys, wallet, EpiPen. That's what I've become accustomed to." (Source: CNN.com - Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SD3ZCO
More than 1 in 10 US adults has a food allergy, study finds
Blake Sorensen of Chicago has a routine: "Phone, keys, wallet, EpiPen. That's what I've become accustomed to." (Source: CNN.com - Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2SD3ZCO
Clinicopathological and prognostic significance of PD-L1 expression in colorectal cancer: a systematic review and meta-analysis
To analyze the prognostic value of programmed death factor ligand 1 (PD-L1) in colorectal cancer.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2CPLuFW
One in 10 adults has a food allergy - but twice as many THINK they do, survey finds
Allergies are on the rise, and now the proportion of US adults with food allergies has outpaced that of children. Still more mistake intolerances for allergies, a Northwestern University study finds. (Source: the Mail online | Health)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tnrobg
Half of people who think they have a food allergy do not – study
US study finds some people needlessly avoid foods while others do not have life-saving medicationThe number of adults who think they have a food allergy is almost double the figure who actually have one, research has revealed.While the study was conducted in the US, experts say a similar situation is also seen in other countries, including the UK. The researchers found that many people with an allergy do not have a prescription for potentially life-saving medication, while others might be avoiding foods unnecessarily.Continue reading... (Source: Guardian Unlimited Science)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2CQ660E
One in 10 Adults Have a Food Allergy. Many More Say They Have One.
More than 26 million American adults have a food allergy; almost as many say they have one but probably don ' t. (Source: NYT Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tss6E2
Fish fumes blamed for allergy death of Brooklyn boy
Police believe fish being cooked may have caused the death of 11-year-old Cameron Jean-Pierre. (Source: BBC News | Health | UK Edition)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2COQj1U
Reducing Corticosteroid-Related Adverse Events in Asthma Reducing Corticosteroid-Related Adverse Events in Asthma
The chronic use of corticosteroids is frequently associated with adverse events in asthmatics. What strategies may help reduce these events?Current Opinion in Allergy and Clinical Immunology (Source: Medscape Today Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2At5IU6
One in 10 adults has a food allergy - but twice as many THINK they do, survey finds
Allergies are on the rise, and now the proportion of US adults with food allergies has outpaced that of children. Still more mistake intolerances for allergies, a Northwestern University study finds. (Source: the Mail online | Health)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tnrobg
Half of people who think they have a food allergy do not – study
US study finds some people needlessly avoid foods while others do not have life-saving medicationThe number of adults who think they have a food allergy is almost double the figure who actually have one, research has revealed.While the study was conducted in the US, experts say a similar situation is also seen in other countries, including the UK. The researchers found that many people with an allergy do not have a prescription for potentially life-saving medication, while others might be avoiding foods unnecessarily.Continue reading... (Source: Guardian Unlimited Science)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2CQ660E
One in 10 Adults Have a Food Allergy. Many More Say They Have One.
More than 26 million American adults have a food allergy; almost as many say they have one but probably don ' t. (Source: NYT Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tss6E2
Fish fumes blamed for allergy death of Brooklyn boy
Police believe fish being cooked may have caused the death of 11-year-old Cameron Jean-Pierre. (Source: BBC News | Health | UK Edition)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2COQj1U
Reducing Corticosteroid-Related Adverse Events in Asthma Reducing Corticosteroid-Related Adverse Events in Asthma
The chronic use of corticosteroids is frequently associated with adverse events in asthmatics. What strategies may help reduce these events?Current Opinion in Allergy and Clinical Immunology (Source: Medscape Today Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2At5IU6
Clinicopathological and prognostic significance of PD-L1 expression in colorectal cancer: a systematic review and meta-analysis
To analyze the prognostic value of programmed death factor ligand 1 (PD-L1) in colorectal cancer.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2CPLuFW
One in 10 adults has a food allergy - but twice as many THINK they do, survey finds
Allergies are on the rise, and now the proportion of US adults with food allergies has outpaced that of children. Still more mistake intolerances for allergies, a Northwestern University study finds. (Source: the Mail online | Health)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tnrobg
Half of people who think they have a food allergy do not – study
US study finds some people needlessly avoid foods while others do not have life-saving medicationThe number of adults who think they have a food allergy is almost double the figure who actually have one, research has revealed.While the study was conducted in the US, experts say a similar situation is also seen in other countries, including the UK. The researchers found that many people with an allergy do not have a prescription for potentially life-saving medication, while others might be avoiding foods unnecessarily.Continue reading... (Source: Guardian Unlimited Science)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2CQ660E
One in 10 Adults Have a Food Allergy. Many More Say They Have One.
More than 26 million American adults have a food allergy; almost as many say they have one but probably don ' t. (Source: NYT Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tss6E2
Fish fumes blamed for allergy death of Brooklyn boy
Police believe fish being cooked may have caused the death of 11-year-old Cameron Jean-Pierre. (Source: BBC News | Health | UK Edition)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2COQj1U
Reducing Corticosteroid-Related Adverse Events in Asthma Reducing Corticosteroid-Related Adverse Events in Asthma
The chronic use of corticosteroids is frequently associated with adverse events in asthmatics. What strategies may help reduce these events?Current Opinion in Allergy and Clinical Immunology (Source: Medscape Today Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2At5IU6
One in 10 adults has a food allergy - but twice as many THINK they do, survey finds
Allergies are on the rise, and now the proportion of US adults with food allergies has outpaced that of children. Still more mistake intolerances for allergies, a Northwestern University study finds. (Source: the Mail online | Health)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tnrobg
Half of people who think they have a food allergy do not – study
US study finds some people needlessly avoid foods while others do not have life-saving medicationThe number of adults who think they have a food allergy is almost double the figure who actually have one, research has revealed.While the study was conducted in the US, experts say a similar situation is also seen in other countries, including the UK. The researchers found that many people with an allergy do not have a prescription for potentially life-saving medication, while others might be avoiding foods unnecessarily.Continue reading... (Source: Guardian Unlimited Science)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2CQ660E
One in 10 Adults Have a Food Allergy. Many More Say They Have One.
More than 26 million American adults have a food allergy; almost as many say they have one but probably don ' t. (Source: NYT Health)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2Tss6E2
Fish fumes blamed for allergy death of Brooklyn boy
Police believe fish being cooked may have caused the death of 11-year-old Cameron Jean-Pierre. (Source: BBC News | Health | UK Edition)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2COQj1U
Reducing Corticosteroid-Related Adverse Events in Asthma Reducing Corticosteroid-Related Adverse Events in Asthma
The chronic use of corticosteroids is frequently associated with adverse events in asthmatics. What strategies may help reduce these events?Current Opinion in Allergy and Clinical Immunology (Source: Medscape Today Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2At5IU6
Review: The relationship of “shisha” (water pipe) smoking to the risk of head and neck cancer
Abstract
Introduction
There has been a recent rise in popularity of waterpipe smoking (WPS) amongst younger people. While it is a tobacco‐related product, research on the possible deleterious effects on health and its relationship with cancer is sparse. In this paper, we evaluated the existing literature and association of WPS with head and neck cancer.
Materials and methods
PubMed, EMBASE, Scopus, Web of Science, and grey literature from January 1990 up to and including March 2017 were searched. Two independent reviewers performed the study selection according to eligibility criteria.
Results
A total of seven studies that met the eligibility criteria were included. In four studies that evaluated the associated risk of oesophageal cancer, the odds ratio (OR) ranged from 1.69 (95% CI=0.76‐3.77) to 21.4 (95% CI=11.6‐39.5). The OR for the association of WPS with nasopharyngeal cancer and oral cancer were reported to be 0.49 (95% CI=0.20‐1.43) and 4.20 (95% CI=1.32‐13.3) respectively. One study that evaluated risk in different head and neck cancers reported two‐fold OR [2.73 (95% CI=1.65–4.41)].
Conclusion
On the basis of our evaluation, there is an association of WPS and head and neck cancer. However, larger studies with standardized methods are needed to identify the possible detrimental health effects of WPS more fully.
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2BZ2FTN
Review: Botulinum toxin in the management of myofascial pain associated with temporomandibular dysfunction
Abstract
Introduction
Critical evidence on the therapeutic efficacy of botulinum toxins (BTX) is still lacking for most pain conditions. The aim of this review was to evaluate the therapeutic efficacy of BTX in the management of temporomandibular myofascial pain.
Materials and methods
Electronic databases PubMed, EMBASE, Scopus, Web of Science, and grey literature were searched for randomized clinical trials until February 2018 to answer a focused question "What is the effectiveness of botulinum toxin in the management of temporomandibular myofascial pain?" Two independent reviewers performed the study selection according to eligibility criteria.
Results
A total of seven studies that met the eligibility criteria were included. Two studies showed a significant improvement in temporomandibular myofascial pain, one study showed equal efficacy of BTX in comparison to facial manipulation, while the remaining studies did not report any significant difference between BTX and control group. Due to heterogeneity in the methodology and outcome assessment, a meta‐analysis and recalculation of risk could not be performed.
Conclusion
Based on our findings, the therapeutic efficacy of BTX was unclear. Randomized controlled trials with better methodological criteria need to be carried out to evaluate the real effectiveness of BTX.
This article is protected by copyright. All rights reserved.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2R8TZVk
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