Δευτέρα 19 Νοεμβρίου 2018

Global Health: Why Don ’ t We Have Vaccines Against Everything?

Money is just the obvious obstacle. A few diseases, like H.I.V., so far have outwitted both the immune system and scientists. (Source: NYT Health)

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Global Health: Why Don ’ t We Have Vaccines Against Everything?

Money is just the obvious obstacle. A few diseases, like H.I.V., so far have outwitted both the immune system and scientists. (Source: NYT Health)

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Identification and Management of Middle Ear Disorders in a Rural Cleft Care Program: A Telemedicine Approach

Conclusions This grassroots-level telemedicine approach was successful in achieving better coverage, and store-and-forward telepractice helped in providing remote diagnosis and recommendation by otolaryngologists to all individuals with TM/MEDs in the rural community. The follow-up for otological intervention significantly improved from that achieved in the previous years. (Source: American Journal of Audiology)

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Innovation in the Context of Audiology and in the Context of the Internet

Conclusions It is unclear presently what types of innovations are likely to have the most profound impacts on audiology in the coming years. In the best case, they will lead to more efficient, effective, and widespread availability of hearing health on a global scale. (Source: American Journal of Audiology)

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Techniques for Remotely Programming Children With Cochlear Implants Using Pediatric Audiological Methods via Telepractice

Conclusions The results from studies to date suggest that distance technology can be used successfully to program CI sound processors for young children using standard, age-appropriate testing techniques. The alternative of remote testing has substantial implications for reducing time and travel burdens for families, potentially leading to the construction of appropriate maps for young children with CIs in a timelier manner. (Source: American Journal of Audiology)

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A Smartphone National Hearing Test: Performance and Characteristics of Users

Conclusions High test uptake, particularly among younger users, and high overall referral rate indicates that the hearZA app addresses a public health need. The test also reaches target audiences, including those with self-reported hearing difficulty and those with normal hearing who should monitor their hearing ability. (Source: American Journal of Audiology)

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Stories From the Webcams: Cincinnati Children's Hospital Medical Center Audiology Telehealth and Pediatric Auditory Device Services

Conclusion The described regulatory, technological, and training hierarchy provides a framework for audiologists interested in starting a telehealth program. The cases presented illustrate that telehealth can be used to provide some auditory device services, such as troubleshooting, mapping, and parent consulting. (Source: American Journal of Audiology)

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Geographic Distribution of the Hearing Aid Dispensing Workforce: A Teleaudiology Planning Assessment for Arizona

Conclusions There are geographic areas of Arizona that lack licensed hearing aid locations yet are populated by individuals who may need services. Resource availability data inform teleaudiology program expansion. Future research will include data from providers and community members on their perceived needs for services. (Source: American Journal of Audiology)

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Findings and Ethical Considerations From a Thematic Analysis of Threads Within Tinnitus Online Support Groups

Conclusions This study represents the 1st research into discussion forums in tinnitus online support groups. A nonintrusive (passive) analysis method was used, whereby messages comprising the dataset were retrieved without direct interaction with the discussion forum. Individuals and the community of tinnitus online support groups are deemed to be at low risk from potential harm in this study. Most tinnitus patients likely benefit from accessing online support groups, for example, they discover they are not alone, and they find new coping strategies. However, for those who are particularly vulnerable or prone to psychological stress, accessing these groups could be detrimental. (Source: American Journal of Audiology)

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Automated Characterization of Mobile Health Apps' Features by Extracting Information From the Web: An Exploratory Study

Conclusions These preliminary results suggested the viability of automated characterization of apps based on text analytics and highlighted directions for improvement in terms of classification rules and vocabularies, analysis of semantic types, and extraction of key features (promoters, services, and users). The availability of automated tools for app characterization is important as it may support health care professionals in informed, aware selection of health apps to recommend to their patients. (Source: American Journal of Audiology)

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Empowering Senior Cochlear Implant Users at Home via a Tablet Computer Application

Conclusions This study evaluated a tablet computer application (MHA) for experienced senior CI users by means of a prospective design, which provided novel insights into delivering CI care into the home of the CI user. The user feedback from this small-scale study suggests that the participants are open to take more responsibility for and to become a more active actor in their own hearing care, if only this is facilitated with the right tools. This may foster the evolution from a clinic-led to a more patient-centered care model, where CI users feel more empowered in the self-management of their hearing implant device. (Source: American Journal of Audiology)

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Toward Better Outcomes in Audiology Distance Education: An Educational Data Mining Approach

Conclusions EDM methods offer new tools to discover knowledge from digital traces (i.e., logs) and support key stakeholders (students, instructors, or course administrators) to raise awareness about course dynamics. This approach has the potential to foster a better understanding and management of educational processes in audiology distance education. (Source: American Journal of Audiology)

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Big Data for Sound Policies: Toward Evidence-Informed Hearing Health Policies

Conclusion In the future, Big Data can inform all steps of the hearing health policy-making process and all levels of hearing health care services. (Source: American Journal of Audiology)

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Identification and Management of Middle Ear Disorders in a Rural Cleft Care Program: A Telemedicine Approach

Conclusions This grassroots-level telemedicine approach was successful in achieving better coverage, and store-and-forward telepractice helped in providing remote diagnosis and recommendation by otolaryngologists to all individuals with TM/MEDs in the rural community. The follow-up for otological intervention significantly improved from that achieved in the previous years. (Source: American Journal of Audiology)

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Long-Term Efficacy of Audiologist-Guided Internet-Based Cognitive Behavior Therapy for Tinnitus

Conclusions The clinical benefits of audiologist-guided iCBT for tinnitus and tinnitus-related difficulties were sustained 1 year postintervention. Predictors of outcome indicated that the intervention is applicable to a wide range of participants regardless of their demographic backgrounds. Attempts should be made to minimize unwanted events in subsequent trials. (Source: American Journal of Audiology)

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Internet and Audiology: A Review of the Third International Meeting

Conclusion Innovations in teleaudiology, mHealth, and Internet-based audiology are developing at a rapid pace and thus research in the field must continue. We invite readers to the next International Meeting on Internet and Audiology that will take place in Southampton, England, June 17 –18, 2019. (Source: American Journal of Audiology)

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Innovation in the Context of Audiology and in the Context of the Internet

Conclusions It is unclear presently what types of innovations are likely to have the most profound impacts on audiology in the coming years. In the best case, they will lead to more efficient, effective, and widespread availability of hearing health on a global scale. (Source: American Journal of Audiology)

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Masthead

(Source: American Journal of Audiology)

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Techniques for Remotely Programming Children With Cochlear Implants Using Pediatric Audiological Methods via Telepractice

Conclusions The results from studies to date suggest that distance technology can be used successfully to program CI sound processors for young children using standard, age-appropriate testing techniques. The alternative of remote testing has substantial implications for reducing time and travel burdens for families, potentially leading to the construction of appropriate maps for young children with CIs in a timelier manner. (Source: American Journal of Audiology)

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Stories From the Webcams: Cincinnati Children's Hospital Medical Center Audiology Telehealth and Pediatric Auditory Device Services

Conclusion The described regulatory, technological, and training hierarchy provides a framework for audiologists interested in starting a telehealth program. The cases presented illustrate that telehealth can be used to provide some auditory device services, such as troubleshooting, mapping, and parent consulting. (Source: American Journal of Audiology)

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Geographic Distribution of the Hearing Aid Dispensing Workforce: A Teleaudiology Planning Assessment for Arizona

Conclusions There are geographic areas of Arizona that lack licensed hearing aid locations yet are populated by individuals who may need services. Resource availability data inform teleaudiology program expansion. Future research will include data from providers and community members on their perceived needs for services. (Source: American Journal of Audiology)

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Findings and Ethical Considerations From a Thematic Analysis of Threads Within Tinnitus Online Support Groups

Conclusions This study represents the 1st research into discussion forums in tinnitus online support groups. A nonintrusive (passive) analysis method was used, whereby messages comprising the dataset were retrieved without direct interaction with the discussion forum. Individuals and the community of tinnitus online support groups are deemed to be at low risk from potential harm in this study. Most tinnitus patients likely benefit from accessing online support groups, for example, they discover they are not alone, and they find new coping strategies. However, for those who are particularly vulnerable or prone to psychological stress, accessing these groups could be detrimental. (Source: American Journal of Audiology)

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Automated Characterization of Mobile Health Apps' Features by Extracting Information From the Web: An Exploratory Study

Conclusions These preliminary results suggested the viability of automated characterization of apps based on text analytics and highlighted directions for improvement in terms of classification rules and vocabularies, analysis of semantic types, and extraction of key features (promoters, services, and users). The availability of automated tools for app characterization is important as it may support health care professionals in informed, aware selection of health apps to recommend to their patients. (Source: American Journal of Audiology)

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User-Innovated eHealth Solutions for Service Delivery to Older Persons With Hearing Impairment

Conclusions Future eHealth solutions must offer personalized rehabilitation strategies that are appropriate for every person with hearing impairment and their level of technical savviness. Thus, a central requirement is anchoring of digital support in the clients' everyday life situations by facilitating easy access to personalized information, communication, and learning milieus. Moreover, the participants' visions for eHealth solutions call for providing both traditional analogue and digital services.Supplemental Materialhttps://doi.org/10.23641/asha.7310729 (Source: American Journal of Audiology)

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Empowering Senior Cochlear Implant Users at Home via a Tablet Computer Application

Conclusions This study evaluated a tablet computer application (MHA) for experienced senior CI users by means of a prospective design, which provided novel insights into delivering CI care into the home of the CI user. The user feedback from this small-scale study suggests that the participants are open to take more responsibility for and to become a more active actor in their own hearing care, if only this is facilitated with the right tools. This may foster the evolution from a clinic-led to a more patient-centered care model, where CI users feel more empowered in the self-management of their hearing implant device. (Source: American Journal of Audiology)

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Toward Better Outcomes in Audiology Distance Education: An Educational Data Mining Approach

Conclusions EDM methods offer new tools to discover knowledge from digital traces (i.e., logs) and support key stakeholders (students, instructors, or course administrators) to raise awareness about course dynamics. This approach has the potential to foster a better understanding and management of educational processes in audiology distance education. (Source: American Journal of Audiology)

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Big Data for Sound Policies: Toward Evidence-Informed Hearing Health Policies

Conclusion In the future, Big Data can inform all steps of the hearing health policy-making process and all levels of hearing health care services. (Source: American Journal of Audiology)

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New Treatment Could Be Breakthrough Against Peanut Allergy

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

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New Treatment Could Be Breakthrough Against Peanut Allergy

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

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New Treatment Could Be Breakthrough Against Peanut Allergy

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

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New Treatment Could Be Breakthrough Against Peanut Allergy

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

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What I Learned at ASHA Convention to Put Into Practice Today

On the first day of last week's highest-attended ASHA Convention in history, Leader editors asked attendees what challenges they wanted to overcome by being there. As the convention drew to a close, we asked: "What did you learn that you can put into practice when you get home?" Based on answers we received, attendees greatly appreciated the hands-on labs running throughout the convention, as well as what they learned from exhibitors, session presenters and conversations with fellow attendees and ASHA staff. Throughout convention, we also asked members what you want to hear on our new podcast launching next year, so please share topics or experts you want to hear in the comment section below. Now, see what practical tips your peers are looking forward to using as soon a...

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What I Learned at ASHA Convention to Put Into Practice Today

On the first day of last week's highest-attended ASHA Convention in history, Leader editors asked attendees what challenges they wanted to overcome by being there. As the convention drew to a close, we asked: "What did you learn that you can put into practice when you get home?" Based on answers we received, attendees greatly appreciated the hands-on labs running throughout the convention, as well as what they learned from exhibitors, session presenters and conversations with fellow attendees and ASHA staff. Throughout convention, we also asked members what you want to hear on our new podcast launching next year, so please share topics or experts you want to hear in the comment section below. Now, see what practical tips your peers are looking forward to using as soon a...

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What Challenges Did You Come to ASHA Convention to Help Overcome?

On the first day of the largest ASHA convention in the organization's history, Leader editors talked to around 600 of the thousands of attendees. We asked about topics we should cover in our new podcast, launching next year. We'd like you to share, too! Please list any topics or experts from the professions you'd like to hear about on the coming Leader podcast in the comment section below. We also asked attendees why they came to Boston in November. We wanted to know what challenges members face and the strategies they hope to learn to help them overcome those challenges. See what your peers shared below. And look for a follow-up post this weekend where attendees share practical ideas they plan to put into practice right away. I lost everything recently in the California wildfires—...

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What I Learned at ASHA Convention to Put Into Practice Today

On the first day of last week's highest-attended ASHA Convention in history, Leader editors asked attendees what challenges they wanted to overcome by being there. As the convention drew to a close, we asked: "What did you learn that you can put into practice when you get home?" Based on answers we received, attendees greatly appreciated the hands-on labs running throughout the convention, as well as what they learned from exhibitors, session presenters and conversations with fellow attendees and ASHA staff. Throughout convention, we also asked members what you want to hear on our new podcast launching next year, so please share topics or experts you want to hear in the comment section below. Now, see what practical tips your peers are looking forward to using as soon a...

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What Challenges Did You Come to ASHA Convention to Help Overcome?

On the first day of the largest ASHA convention in the organization's history, Leader editors talked to around 600 of the thousands of attendees. We asked about topics we should cover in our new podcast, launching next year. We'd like you to share, too! Please list any topics or experts from the professions you'd like to hear about on the coming Leader podcast in the comment section below. We also asked attendees why they came to Boston in November. We wanted to know what challenges members face and the strategies they hope to learn to help them overcome those challenges. See what your peers shared below. And look for a follow-up post this weekend where attendees share practical ideas they plan to put into practice right away. I lost everything recently in the California wildfires—...

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A Ball of Fun: Allergic Bronchopulmonary Aspergillosis Presenting as a Pneumothorax

Conference abstracts (Source: The Aspergillus Website - updates)

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Efficacy of Mucolytic Treatment in Decreasing Airway Resistance and Increasing Mucus Clearance in a Mouse Model of Allergic Asthma

Conference abstracts (Source: The Aspergillus Website - updates)

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Oxidative Damage Abolishes the Ability of SP-D to Block Eosinophil Extracellular DNA Trap Release During Exacerbation of Allergic Airway Inflammation

Conference abstracts (Source: The Aspergillus Website - updates)

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Researchers find promise in new treatment for peanut allergy

(University of Chicago Medical Center) Controlled ingestion of peanut protein could help build tolerance in peanut allergy sufferers. Authors of a new study published in the New England Journal of Medicine say an oral immunotherapy drug they tested could be the first FDA-approved medication of its kind for people with peanut allergy. The medication, called AR101, is derived from peanut protein. (Source: EurekAlert! - Medicine and Health)

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A Ball of Fun: Allergic Bronchopulmonary Aspergillosis Presenting as a Pneumothorax

Conference abstracts (Source: The Aspergillus Website - updates)

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Efficacy of Mucolytic Treatment in Decreasing Airway Resistance and Increasing Mucus Clearance in a Mouse Model of Allergic Asthma

Conference abstracts (Source: The Aspergillus Website - updates)

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Oxidative Damage Abolishes the Ability of SP-D to Block Eosinophil Extracellular DNA Trap Release During Exacerbation of Allergic Airway Inflammation

Conference abstracts (Source: The Aspergillus Website - updates)

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Researchers find promise in new treatment for peanut allergy

(University of Chicago Medical Center) Controlled ingestion of peanut protein could help build tolerance in peanut allergy sufferers. Authors of a new study published in the New England Journal of Medicine say an oral immunotherapy drug they tested could be the first FDA-approved medication of its kind for people with peanut allergy. The medication, called AR101, is derived from peanut protein. (Source: EurekAlert! - Medicine and Health)

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A Ball of Fun: Allergic Bronchopulmonary Aspergillosis Presenting as a Pneumothorax

Conference abstracts (Source: The Aspergillus Website - updates)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S0Xx7S

Efficacy of Mucolytic Treatment in Decreasing Airway Resistance and Increasing Mucus Clearance in a Mouse Model of Allergic Asthma

Conference abstracts (Source: The Aspergillus Website - updates)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DNc3gC

Oxidative Damage Abolishes the Ability of SP-D to Block Eosinophil Extracellular DNA Trap Release During Exacerbation of Allergic Airway Inflammation

Conference abstracts (Source: The Aspergillus Website - updates)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S0XsB6

Researchers find promise in new treatment for peanut allergy

(University of Chicago Medical Center) Controlled ingestion of peanut protein could help build tolerance in peanut allergy sufferers. Authors of a new study published in the New England Journal of Medicine say an oral immunotherapy drug they tested could be the first FDA-approved medication of its kind for people with peanut allergy. The medication, called AR101, is derived from peanut protein. (Source: EurekAlert! - Medicine and Health)

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What I Learned at ASHA Convention to Put Into Practice Today

On the first day of last week's highest-attended ASHA Convention in history, Leader editors asked attendees what challenges they wanted to overcome by being there. As the convention drew to a close, we asked: "What did you learn that you can put into practice when you get home?" Based on answers we received, attendees greatly appreciated the hands-on labs running throughout the convention, as well as what they learned from exhibitors, session presenters and conversations with fellow attendees and ASHA staff. Throughout convention, we also asked members what you want to hear on our new podcast launching next year, so please share topics or experts you want to hear in the comment section below. Now, see what practical tips your peers are looking forward to using as soon a...

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S4j5An

A Ball of Fun: Allergic Bronchopulmonary Aspergillosis Presenting as a Pneumothorax

Conference abstracts (Source: The Aspergillus Website - updates)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S0Xx7S

Efficacy of Mucolytic Treatment in Decreasing Airway Resistance and Increasing Mucus Clearance in a Mouse Model of Allergic Asthma

Conference abstracts (Source: The Aspergillus Website - updates)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DNc3gC

Oxidative Damage Abolishes the Ability of SP-D to Block Eosinophil Extracellular DNA Trap Release During Exacerbation of Allergic Airway Inflammation

Conference abstracts (Source: The Aspergillus Website - updates)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S0XsB6

Researchers find promise in new treatment for peanut allergy

(University of Chicago Medical Center) Controlled ingestion of peanut protein could help build tolerance in peanut allergy sufferers. Authors of a new study published in the New England Journal of Medicine say an oral immunotherapy drug they tested could be the first FDA-approved medication of its kind for people with peanut allergy. The medication, called AR101, is derived from peanut protein. (Source: EurekAlert! - Medicine and Health)

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What I Learned at ASHA Convention to Put Into Practice Today

On the first day of last week's highest-attended ASHA Convention in history, Leader editors asked attendees what challenges they wanted to overcome by being there. As the convention drew to a close, we asked: "What did you learn that you can put into practice when you get home?" Based on answers we received, attendees greatly appreciated the hands-on labs running throughout the convention, as well as what they learned from exhibitors, session presenters and conversations with fellow attendees and ASHA staff. Throughout convention, we also asked members what you want to hear on our new podcast launching next year, so please share topics or experts you want to hear in the comment section below. Now, see what practical tips your peers are looking forward to using as soon a...

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Selective rickets from localized advanced maturation—a case report

Abstract

An unusual cause of rickets is illustrated by a patient with infantile multisystem inflammatory disease who, by age 2 years and 4 months, developed striking radiographic and clinical rickets restricted to those joints involved by the inflammatory process. The locally increased vascularity from his inflammation led to increased maturation at those sites so rapid as to override the usual enchondral calcification, thus causing a rickets pattern. Other sites, such as the proximal humeri, lacking any inflammation, showed no increased maturation rate and did not manifest local rickets. Rapid local bone maturation may cause localized rickets.



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Selective rickets from localized advanced maturation—a case report

Abstract

An unusual cause of rickets is illustrated by a patient with infantile multisystem inflammatory disease who, by age 2 years and 4 months, developed striking radiographic and clinical rickets restricted to those joints involved by the inflammatory process. The locally increased vascularity from his inflammation led to increased maturation at those sites so rapid as to override the usual enchondral calcification, thus causing a rickets pattern. Other sites, such as the proximal humeri, lacking any inflammation, showed no increased maturation rate and did not manifest local rickets. Rapid local bone maturation may cause localized rickets.



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Training Groups



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Editorial Board



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Training Groups



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Editorial Board



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First-ever treatment for peanut allergies shows positive study results

An experimental treatment is giving new hope to peanut allergy sufferers. (Source: PharmaManufacturing.com)

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New peanut allergy drug could herald a ‘sea change’ in treating food allergies but is not a cure

A large clinical trial showed that children and teenagers could be desensitized to peanut allergies with an experimental drug, but the treatment had a high risk of adverse events. (Source: Washington Post: To Your Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qWJcxC

Nearly 1 in 12 U.S. Kids Has a Food Allergy

Childhood food allergies are relatively common and should be taken seriously, with 1 in 5 having a reaction that takes them to the emergency room every year. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FwaG7J

Prevalence of Food Allergy 7.6 Percent in U.S. Children

MONDAY, Nov. 19, 2018 -- The prevalence of food allergy (FA) is 7.6 percent among children in the United States, according to a study published online Nov. 19 in Pediatrics. Ruchi S. Gupta, M.D., M.P.H., from Northwestern University in Chicago, and... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qULhu0

ACAAI: Oral Immunotherapy Is Protective in Peanut Allergy

MONDAY, Nov. 19, 2018 -- Patients with peanut allergy who received oral immunotherapy, compared with those who received placebo, were able to ingest higher doses of peanut protein without dose-limiting symptoms, according to a study published online... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FznZnJ

Nearly 1 in 12 U.S. Kids Has a Food Allergy

MONDAY, Nov. 19, 2018 -- Almost 8 percent of American children have food allergies, and 1 in 5 of those kids suffers an allergic reaction severe enough to wind up in the hospital, a new study finds. " Childhood food allergies are relatively common... (Source: Drugs.com - Daily MedNews)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qVUB0J

New peanut allergy drug could herald a ‘sea change’ in treating food allergies but is not a cure

A large clinical trial showed that children and teenagers could be desensitized to peanut allergies with an experimental drug, but the treatment had a high risk of adverse events. (Source: Washington Post: To Your Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qWJcxC

Nearly 1 in 12 U.S. Kids Has a Food Allergy

Childhood food allergies are relatively common and should be taken seriously, with 1 in 5 having a reaction that takes them to the emergency room every year. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FwaG7J

Prevalence of Food Allergy 7.6 Percent in U.S. Children

MONDAY, Nov. 19, 2018 -- The prevalence of food allergy (FA) is 7.6 percent among children in the United States, according to a study published online Nov. 19 in Pediatrics. Ruchi S. Gupta, M.D., M.P.H., from Northwestern University in Chicago, and... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qULhu0

ACAAI: Oral Immunotherapy Is Protective in Peanut Allergy

MONDAY, Nov. 19, 2018 -- Patients with peanut allergy who received oral immunotherapy, compared with those who received placebo, were able to ingest higher doses of peanut protein without dose-limiting symptoms, according to a study published online... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FznZnJ

Nearly 1 in 12 U.S. Kids Has a Food Allergy

MONDAY, Nov. 19, 2018 -- Almost 8 percent of American children have food allergies, and 1 in 5 of those kids suffers an allergic reaction severe enough to wind up in the hospital, a new study finds. " Childhood food allergies are relatively common... (Source: Drugs.com - Daily MedNews)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qVUB0J

First-ever treatment for peanut allergies shows positive study results

An experimental treatment is giving new hope to peanut allergy sufferers. (Source: PharmaManufacturing.com)

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Frkcc2

New peanut allergy drug could herald a ‘sea change’ in treating food allergies but is not a cure

A large clinical trial showed that children and teenagers could be desensitized to peanut allergies with an experimental drug, but the treatment had a high risk of adverse events. (Source: Washington Post: To Your Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qWJcxC

Nearly 1 in 12 U.S. Kids Has a Food Allergy

Childhood food allergies are relatively common and should be taken seriously, with 1 in 5 having a reaction that takes them to the emergency room every year. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FwaG7J

Prevalence of Food Allergy 7.6 Percent in U.S. Children

MONDAY, Nov. 19, 2018 -- The prevalence of food allergy (FA) is 7.6 percent among children in the United States, according to a study published online Nov. 19 in Pediatrics. Ruchi S. Gupta, M.D., M.P.H., from Northwestern University in Chicago, and... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qULhu0

ACAAI: Oral Immunotherapy Is Protective in Peanut Allergy

MONDAY, Nov. 19, 2018 -- Patients with peanut allergy who received oral immunotherapy, compared with those who received placebo, were able to ingest higher doses of peanut protein without dose-limiting symptoms, according to a study published online... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FznZnJ

Nearly 1 in 12 U.S. Kids Has a Food Allergy

MONDAY, Nov. 19, 2018 -- Almost 8 percent of American children have food allergies, and 1 in 5 of those kids suffers an allergic reaction severe enough to wind up in the hospital, a new study finds. " Childhood food allergies are relatively common... (Source: Drugs.com - Daily MedNews)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qVUB0J

First-ever treatment for peanut allergies shows positive study results

An experimental treatment is giving new hope to peanut allergy sufferers. (Source: PharmaManufacturing.com)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Frkcc2

Nearly 1 in 12 U.S. Kids Has a Food Allergy

Childhood food allergies are relatively common and should be taken seriously, with 1 in 5 having a reaction that takes them to the emergency room every year. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FwaG7J

Prevalence of Food Allergy 7.6 Percent in U.S. Children

MONDAY, Nov. 19, 2018 -- The prevalence of food allergy (FA) is 7.6 percent among children in the United States, according to a study published online Nov. 19 in Pediatrics. Ruchi S. Gupta, M.D., M.P.H., from Northwestern University in Chicago, and... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qULhu0

ACAAI: Oral Immunotherapy Is Protective in Peanut Allergy

MONDAY, Nov. 19, 2018 -- Patients with peanut allergy who received oral immunotherapy, compared with those who received placebo, were able to ingest higher doses of peanut protein without dose-limiting symptoms, according to a study published online... (Source: Drugs.com - Pharma News)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FznZnJ

Nearly 1 in 12 U.S. Kids Has a Food Allergy

MONDAY, Nov. 19, 2018 -- Almost 8 percent of American children have food allergies, and 1 in 5 of those kids suffers an allergic reaction severe enough to wind up in the hospital, a new study finds. " Childhood food allergies are relatively common... (Source: Drugs.com - Daily MedNews)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qVUB0J

Changes of hemodynamic and cerebral oxygenation after exercise in normobaric and hypobaric hypoxia: associations with acute mountain sickness

Normobaric (NH) and hypobaric hypoxia (HH) are associated with acute mountain sickness (AMS) and cognitive dysfunction. Only few variables, like heart-rate-variability, are correlated with AMS. However, predic...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zjYilL

Changes of hemodynamic and cerebral oxygenation after exercise in normobaric and hypobaric hypoxia: associations with acute mountain sickness

Normobaric (NH) and hypobaric hypoxia (HH) are associated with acute mountain sickness (AMS) and cognitive dysfunction. Only few variables, like heart-rate-variability, are correlated with AMS. However, predic...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zjYilL

The Three Dimensional Orofacial Changes Occurring After Proportional Condylectomy in Patients with Condylar Hyperplasia Type 1B (Unilateral Hemimandibular Elongation)

To evaluate the three dimensional orofacial changes occurring after proportional condylectomy that was not followed by orthognathic surgery in patients with condylar hyperplasia type 1B (unilateral hemimandibular elongation).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QWwN8z

Pediatricians ’ proficiency in the care of the dysphonic child

ConclusionsVeteran pediatricians feel more comfortable diagnosing a voice disorder and are more likely to refer a DC, regardless of patient/parent complaints or compounding factors. Pediatricians are most likely to refer to a pediatric otolaryngologist versus a voice specialist. These findings suggest that education of younger, less ‐experienced pediatricians about recognizing voice disorders and options for referral is needed. This may improve the overall care of the DC.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PJhqnu

Mortality associated with tracheostomy complications in the United States: 2007 –2016

ConclusionsTracheostomy ‐related complications were implicated in the deaths of a significant number of individuals. Several demographic groups had increased likelihood of tracheostomy‐related mortality. Future research is necessary to develop targeted interventions to decrease harm.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QUJvo5

Experimental animal model for assessment of tracheal epithelium regeneration

ConclusionWe present an experimental in vivo animal model of tracheal epithelium injury and recovery. It can be effectively used with certain further modifications as a basis for routine testing of bioengineered constructs.Level of EvidenceNA.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R1LRBW

Nimodipine improves vocal fold and facial motion recovery after injury: A systematic review and meta ‐analysis

ConclusionExisting evidence supports the positive effect of nimodipine on vocal fold and facial motion recovery after injury. Future research should focus on randomized clinical trials comparing recovery rates between nimodipine ‐ and placebo‐treated groups.Level of Evidence2a.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PEbThO

Characterization of aged rat vocal fold fibroblasts

ConclusionsThe following possible characteristics of aged VFFs were implied: long duration of mitosis, increased myofibroblast population size with certain dysfunctions, reduced type I collagen turnover, and correlation between α‐SMA expression and type I collagen metabolism. Further investigations of these features will help to clarify presbyphonia's pathology and establish treatment strategies.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QYoIQv

Pediatricians ’ proficiency in the care of the dysphonic child

ConclusionsVeteran pediatricians feel more comfortable diagnosing a voice disorder and are more likely to refer a DC, regardless of patient/parent complaints or compounding factors. Pediatricians are most likely to refer to a pediatric otolaryngologist versus a voice specialist. These findings suggest that education of younger, less ‐experienced pediatricians about recognizing voice disorders and options for referral is needed. This may improve the overall care of the DC.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PJhqnu

Mortality associated with tracheostomy complications in the United States: 2007 –2016

ConclusionsTracheostomy ‐related complications were implicated in the deaths of a significant number of individuals. Several demographic groups had increased likelihood of tracheostomy‐related mortality. Future research is necessary to develop targeted interventions to decrease harm.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QUJvo5

Ultrasonographic assessment of costochondral cartilage for microtia reconstruction

The Laryngoscope, EarlyView. (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PJhrYA

Nimodipine improves vocal fold and facial motion recovery after injury: A systematic review and meta ‐analysis

ConclusionExisting evidence supports the positive effect of nimodipine on vocal fold and facial motion recovery after injury. Future research should focus on randomized clinical trials comparing recovery rates between nimodipine ‐ and placebo‐treated groups.Level of Evidence2a.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PEbThO

Changing trends in management of vestibular schwannoma: A National Cancer Database study

ConclusionManagement of VS is shifting toward increased observation, most significantly in tumors size  <  1 cm. Insurance provider plays a significant role on receipt of treatment and modality, whereas income and education do not.Level of EvidenceN/ALaryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QR7SmG

Endoscopic endonasal resection of adenoid cystic carcinoma of the sinonasal tract and skull base

ConclusionsThe endoscopic approach is safe and effective for selected sinonasal ACC, reducing the comorbidities of the external approaches while producing similar oncological results. High T ‐stage, grade III histology, positive surgical margins, and perineural infiltration all have an important negative prognostic value.Level of Evidence4.Laryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PFPy3w

Characterization of aged rat vocal fold fibroblasts

ConclusionsThe following possible characteristics of aged VFFs were implied: long duration of mitosis, increased myofibroblast population size with certain dysfunctions, reduced type I collagen turnover, and correlation between α‐SMA expression and type I collagen metabolism. Further investigations of these features will help to clarify presbyphonia's pathology and establish treatment strategies.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QYoIQv

The Three Dimensional Orofacial Changes Occurring After Proportional Condylectomy in Patients with Condylar Hyperplasia Type 1B (Unilateral Hemimandibular Elongation)

To evaluate the three dimensional orofacial changes occurring after proportional condylectomy that was not followed by orthognathic surgery in patients with condylar hyperplasia type 1B (unilateral hemimandibular elongation).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QWwN8z

The Three Dimensional Orofacial Changes Occurring After Proportional Condylectomy in Patients with Condylar Hyperplasia Type 1B (Unilateral Hemimandibular Elongation)

To evaluate the three dimensional orofacial changes occurring after proportional condylectomy that was not followed by orthognathic surgery in patients with condylar hyperplasia type 1B (unilateral hemimandibular elongation).

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QWwN8z

Time-Compressed Speech Identification Is Predicted by Auditory Neural Processing, Perceptuomotor Speed, and Executive Functioning in Younger and Older Listeners

AbstractOlder adults typically have difficulty identifying speech that is temporally distorted, such as reverberant, accented, time-compressed, or interrupted speech. These difficulties occur even when hearing thresholds fall within a normal range. Auditory neural processing speed, which we have previously found to predict auditory temporal processing (auditory gap detection), may interfere with the ability to recognize phonetic features as they rapidly unfold over time in spoken speech. Further, declines in perceptuomotor processing speed and executive functioning may interfere with the ability to track, access, and process information. The current investigation examined the extent to which age-related differences in time-compressed speech identification were predicted by auditory neural ...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FrhtPQ

Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users

AbstractPoor spectral resolution contributes to the difficulties experienced by cochlear implant (CI) users when listening to speech in noise. However, correlations between measures of spectral resolution and speech perception in noise have not always been found to be robust. It may be that the relationship between spectral resolution and speech perception in noise becomes clearer in conditions where the speech and noise are not spectrally matched, so that improved spectral resolution can assist in separating the speech from the masker. To test this prediction, speech intelligibility was measured with noise or tone maskers that were presented either in the same spectral channels as the speech or in interleaved spectral channels. Spectral resolution was estimated via a spectral ripple discr...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qT6sg6

Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E

Extracellular matrix proteins tenascin-C (TNC) and periostin, which were identified as T-helper cell type 2 cytokine-induced genes in human bronchial epithelial cells, accumulate in the airway basement membran...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QSjmGB

Fetal cord blood and tissue immune responses to chronic placental inflammation and chorioamnionitis

Chorioamnionitis is a risk factor for future asthma development. Animal models of chorioamnionitis demonstrate increased TH17-to-Treg ratios associated with proinflammatory cytokine elevations. The association of...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PG00I8

Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users

AbstractPoor spectral resolution contributes to the difficulties experienced by cochlear implant (CI) users when listening to speech in noise. However, correlations between measures of spectral resolution and speech perception in noise have not always been found to be robust. It may be that the relationship between spectral resolution and speech perception in noise becomes clearer in conditions where the speech and noise are not spectrally matched, so that improved spectral resolution can assist in separating the speech from the masker. To test this prediction, speech intelligibility was measured with noise or tone maskers that were presented either in the same spectral channels as the speech or in interleaved spectral channels. Spectral resolution was estimated via a spectral ripple discr...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qT6sg6

The clinical burden of allergic rhinitis in five Middle Eastern countries: results of the SNAPSHOT program

The SNAPSHOT program provides current data on the allergic rhinitis burden in the adult general population of five Middle Eastern countries (Egypt, Turkey, Kuwait, Saudi Arabia and the United Arab Emirates, th...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PBqwm1

Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E

Extracellular matrix proteins tenascin-C (TNC) and periostin, which were identified as T-helper cell type 2 cytokine-induced genes in human bronchial epithelial cells, accumulate in the airway basement membran...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QSjmGB

Fetal cord blood and tissue immune responses to chronic placental inflammation and chorioamnionitis

Chorioamnionitis is a risk factor for future asthma development. Animal models of chorioamnionitis demonstrate increased TH17-to-Treg ratios associated with proinflammatory cytokine elevations. The association of...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PG00I8

New treatment may be "breakthrough" for peanut allergies

New research offers hope for the millions of children in the U.S. who suffer from peanut allergies (Source: Health News: CBSNews.com)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OPXAl7

New peanut allergy drug could herald a ‘sea change’ in treating food allergies, but is not a cure

A large clinical trial showed that children and teenagers could be desensitized to peanut allergies with an experimental drug, but the treatment had a high risk of adverse events. (Source: Washington Post: To Your Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zi3ZAk

New treatment may be "breakthrough" for peanut allergies

New research offers hope for the millions of children in the U.S. who suffer from peanut allergies (Source: Health News: CBSNews.com)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OPXAl7

New peanut allergy drug could herald a ‘sea change’ in treating food allergies, but is not a cure

A large clinical trial showed that children and teenagers could be desensitized to peanut allergies with an experimental drug, but the treatment had a high risk of adverse events. (Source: Washington Post: To Your Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zi3ZAk

Oral & Maxillofacial surgery is ready for patient-centred eHealth interventions − the outcomes of a scoping review

Within the field of oral and maxillofacial (OMF) surgery, eHealth is expected to be a tool to improve quality of care. The aim of this study is to map the research of patient-centred eHealth interventions within OMF surgery by means of a scoping review.After a systematic literature search, relevant studies on patient-centred eHealth interventions for OMF-surgery patients were selected. The interventions were mapped based on their key components, target population and outcome measures. To gain insight in the research phase of evaluation, the framework of the Medical Research Council (MRC) was used.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FwcTQu

Oral & Maxillofacial surgery is ready for patient-centred eHealth interventions − the outcomes of a scoping review

Within the field of oral and maxillofacial (OMF) surgery, eHealth is expected to be a tool to improve quality of care. The aim of this study is to map the research of patient-centred eHealth interventions within OMF surgery by means of a scoping review.After a systematic literature search, relevant studies on patient-centred eHealth interventions for OMF-surgery patients were selected. The interventions were mapped based on their key components, target population and outcome measures. To gain insight in the research phase of evaluation, the framework of the Medical Research Council (MRC) was used.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FwcTQu

New peanut allergy drug could herald a ‘sea change’ in treating food allergies, but is not a cure

A large clinical trial showed that children and teenagers could be desensitized to peanut allergies with an experimental drug, but the treatment had a high risk of adverse events. (Source: Washington Post: To Your Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2zi3ZAk

New treatment may be "breakthrough" for peanut allergies

New research offers hope for the millions of children in the U.S. who suffer from peanut allergies (Source: Health News: CBSNews.com)

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OPXAl7

Necrostatin-1 protects against ischemia/reperfusion injury by inhibiting receptor-interacting protein 1 in a rat flap model

: The failure of reconstructive surgeries remains a challenge for plastic surgeons. Ischemia reperfusion (I/R) injury is considered to be one of the major problems in flap surgery. Necroptosis is a recently discovered and caspase-3 independent programmed necrosis. Necrostatin-1 (Nec-1) is a specific inhibitor of necroptosis. Reports indicate that Nec-1 provides protection in ischemic models, such as brain, kidney and heart. The aim of this study is to investigate the influence of Nec-1 on the I/R process in rat abdominal skin flaps.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FIAm15

Compartimental harvesting of dual lymph node flap from the right supraclavicular area for the treatment of lower extremity lymphedema: a case series

We report our clinical experience of supraclavicular lymph node flap (LNF) using a novel method of harvesting based on the compartimental lymphatic and vascular anatomy of the right posterior neck triangle, that allows to harvest two indipendent LNFs from the same donor-site.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qT7usx

Necrostatin-1 protects against ischemia/reperfusion injury by inhibiting receptor-interacting protein 1 in a rat flap model

: The failure of reconstructive surgeries remains a challenge for plastic surgeons. Ischemia reperfusion (I/R) injury is considered to be one of the major problems in flap surgery. Necroptosis is a recently discovered and caspase-3 independent programmed necrosis. Necrostatin-1 (Nec-1) is a specific inhibitor of necroptosis. Reports indicate that Nec-1 provides protection in ischemic models, such as brain, kidney and heart. The aim of this study is to investigate the influence of Nec-1 on the I/R process in rat abdominal skin flaps.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2FIAm15

Compartimental harvesting of dual lymph node flap from the right supraclavicular area for the treatment of lower extremity lymphedema: a case series

We report our clinical experience of supraclavicular lymph node flap (LNF) using a novel method of harvesting based on the compartimental lymphatic and vascular anatomy of the right posterior neck triangle, that allows to harvest two indipendent LNFs from the same donor-site.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qT7usx

Audiological and clinical outcomes of a transcutaneous bone conduction hearing implant: Six ‐month results from a multicentre study

ConclusionsThe Baha Attract System provided a significant improvement in hearing performance and subjective benefit compared to the pre ‐operative unaided condition (with the non‐test ear blocked). Hearing performance of the Baha Attract was similar to a test situation with the same sound processor on a softband. A proportion of the patients reported numbness and pain/discomfort at the implant site during follow‐up, especially during the first post‐operative weeks. Based on the results of the current multicentre study, the Baha Attract can be considered as a treatment option for patients with the aforementioned hearing losses. Especially in the SSD patients, a careful selection procedure is warranted. Therefore, a pre‐ operative trial should be part of the decision‐making proce...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Fyys2N

A call for feedback on postoperative care: Do we need an automated tool?



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qWriv0

Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users

AbstractPoor spectral resolution contributes to the difficulties experienced by cochlear implant (CI) users when listening to speech in noise. However, correlations between measures of spectral resolution and speech perception in noise have not always been found to be robust. It may be that the relationship between spectral resolution and speech perception in noise becomes clearer in conditions where the speech and noise are not spectrally matched, so that improved spectral resolution can assist in separating the speech from the masker. To test this prediction, speech intelligibility was measured with noise or tone maskers that were presented either in the same spectral channels as the speech or in interleaved spectral channels. Spectral resolution was estimated via a spectral ripple discr...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qT6sg6

Audiological and clinical outcomes of a transcutaneous bone conduction hearing implant: Six ‐month results from a multicentre study

ConclusionsThe Baha Attract System provided a significant improvement in hearing performance and subjective benefit compared to the pre ‐operative unaided condition (with the non‐test ear blocked). Hearing performance of the Baha Attract was similar to a test situation with the same sound processor on a softband. A proportion of the patients reported numbness and pain/discomfort at the implant site during follow‐up, especially during the first post‐operative weeks. Based on the results of the current multicentre study, the Baha Attract can be considered as a treatment option for patients with the aforementioned hearing losses. Especially in the SSD patients, a careful selection procedure is warranted. Therefore, a pre‐ operative trial should be part of the decision‐making proce...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Fyys2N

A call for feedback on postoperative care: Do we need an automated tool?



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qWriv0

Correction to: Metformin improved health-related quality of life in ethnic Chinese women with polycystic ovary syndrome

The original article [1] contains a number of statements that the authors would like to be disregarded, noted ahead

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QQRO4m

Comparing assessment of diabetes-related quality of life between patients and their physicians

Health-related quality of life (QoL) is a comprehensive, multidimensional construct encompassing physical and psychosocial wellbeing. Physicians frequently assess QoL as part of their decision making process w...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PJ7Y3u

Patient-reported outcomes from a randomized phase II study of the deferasirox film-coated tablet in patients with transfusion-dependent anemias

Adherence to long-term chelation therapy in transfusion-dependent patients is critical to prevent iron overload-related complications. Once-daily deferasirox dispersible tablets (DT) have proven long-term effi...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QVVyBP

Patient reported barriers are associated with low physical and mental well-being in patients with co-morbid diabetes and chronic kidney disease

Little is known about how patient reported barriers to health care impact the quality of life (HRQoL) of patients with comorbid disease. We investigated patient reported barriers to health care and low physica...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PBis4J

The association between paralytic side and health-related quality of life in facial palsy: a cross-sectional study of the Korea National Health and Nutrition Examination Survey (2008–2012)

Facial palsy is known to have correlations with low level of quality of life. However, little is known about the association between preference based health-related quality of life (HRQoL) and paralytic side o...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QQRRx4

Correction to: Metformin improved health-related quality of life in ethnic Chinese women with polycystic ovary syndrome

The original article [1] contains a number of statements that the authors would like to be disregarded, noted ahead

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QQRO4m

Comparing assessment of diabetes-related quality of life between patients and their physicians

Health-related quality of life (QoL) is a comprehensive, multidimensional construct encompassing physical and psychosocial wellbeing. Physicians frequently assess QoL as part of their decision making process w...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PJ7Y3u

Patient-reported outcomes from a randomized phase II study of the deferasirox film-coated tablet in patients with transfusion-dependent anemias

Adherence to long-term chelation therapy in transfusion-dependent patients is critical to prevent iron overload-related complications. Once-daily deferasirox dispersible tablets (DT) have proven long-term effi...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QVVyBP

Patient reported barriers are associated with low physical and mental well-being in patients with co-morbid diabetes and chronic kidney disease

Little is known about how patient reported barriers to health care impact the quality of life (HRQoL) of patients with comorbid disease. We investigated patient reported barriers to health care and low physica...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PBis4J

The association between paralytic side and health-related quality of life in facial palsy: a cross-sectional study of the Korea National Health and Nutrition Examination Survey (2008–2012)

Facial palsy is known to have correlations with low level of quality of life. However, little is known about the association between preference based health-related quality of life (HRQoL) and paralytic side o...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QQRRx4

Deep cheek fat flap: new technique to augment the soft tissues of the mandibular alveolus

Deep cheek fat is found in distinct compartments, which are separated by septae1 and, together with other compartments of facial fat, are currently "hot" topics in the rejuvenation of the face. They serve as a map for facial ageing, and are considered to be the best positioning system for injecting fillers.2 Apart from the buccal fat pad, however, this extraoral fat has not, to the best of my knowledge, been used in implant dentistry.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Fx8zQY

Deep cheek fat flap: new technique to augment the soft tissues of the mandibular alveolus

Deep cheek fat is found in distinct compartments, which are separated by septae1 and, together with other compartments of facial fat, are currently "hot" topics in the rejuvenation of the face. They serve as a map for facial ageing, and are considered to be the best positioning system for injecting fillers.2 Apart from the buccal fat pad, however, this extraoral fat has not, to the best of my knowledge, been used in implant dentistry.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Fx8zQY

Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users

Abstract

Poor spectral resolution contributes to the difficulties experienced by cochlear implant (CI) users when listening to speech in noise. However, correlations between measures of spectral resolution and speech perception in noise have not always been found to be robust. It may be that the relationship between spectral resolution and speech perception in noise becomes clearer in conditions where the speech and noise are not spectrally matched, so that improved spectral resolution can assist in separating the speech from the masker. To test this prediction, speech intelligibility was measured with noise or tone maskers that were presented either in the same spectral channels as the speech or in interleaved spectral channels. Spectral resolution was estimated via a spectral ripple discrimination task. Results from vocoder simulations in normal-hearing listeners showed increasing differences in speech intelligibility between spectrally overlapped and interleaved maskers as well as improved spectral ripple discrimination with increasing spectral resolution. However, no clear differences were observed in CI users between performance with spectrally interleaved and overlapped maskers, or between tone and noise maskers. The results suggest that spectral resolution in current CIs is too poor to take advantage of the spectral separation produced by spectrally interleaved speech and maskers. Overall, the spectrally interleaved and tonal maskers produce a much larger difference in performance between normal-hearing listeners and CI users than do traditional speech-in-noise measures, and thus provide a more sensitive test of speech perception abilities for current and future implantable devices.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tpb2zH

Clinical features of poorly differentiated thyroid papillary carcinoma

To investigate the clinical feature of the poorly differentiated thyroid papillary carcinoma.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qUxiEH

Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users

Abstract

Poor spectral resolution contributes to the difficulties experienced by cochlear implant (CI) users when listening to speech in noise. However, correlations between measures of spectral resolution and speech perception in noise have not always been found to be robust. It may be that the relationship between spectral resolution and speech perception in noise becomes clearer in conditions where the speech and noise are not spectrally matched, so that improved spectral resolution can assist in separating the speech from the masker. To test this prediction, speech intelligibility was measured with noise or tone maskers that were presented either in the same spectral channels as the speech or in interleaved spectral channels. Spectral resolution was estimated via a spectral ripple discrimination task. Results from vocoder simulations in normal-hearing listeners showed increasing differences in speech intelligibility between spectrally overlapped and interleaved maskers as well as improved spectral ripple discrimination with increasing spectral resolution. However, no clear differences were observed in CI users between performance with spectrally interleaved and overlapped maskers, or between tone and noise maskers. The results suggest that spectral resolution in current CIs is too poor to take advantage of the spectral separation produced by spectrally interleaved speech and maskers. Overall, the spectrally interleaved and tonal maskers produce a much larger difference in performance between normal-hearing listeners and CI users than do traditional speech-in-noise measures, and thus provide a more sensitive test of speech perception abilities for current and future implantable devices.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tpb2zH

Time-Compressed Speech Identification Is Predicted by Auditory Neural Processing, Perceptuomotor Speed, and Executive Functioning in Younger and Older Listeners

Abstract

Older adults typically have difficulty identifying speech that is temporally distorted, such as reverberant, accented, time-compressed, or interrupted speech. These difficulties occur even when hearing thresholds fall within a normal range. Auditory neural processing speed, which we have previously found to predict auditory temporal processing (auditory gap detection), may interfere with the ability to recognize phonetic features as they rapidly unfold over time in spoken speech. Further, declines in perceptuomotor processing speed and executive functioning may interfere with the ability to track, access, and process information. The current investigation examined the extent to which age-related differences in time-compressed speech identification were predicted by auditory neural processing speed, perceptuomotor processing speed, and executive functioning. Groups of normal-hearing (up to 3000 Hz) younger and older adults identified 40, 50, and 60 % time-compressed sentences. Auditory neural processing speed was defined as the P1 and N1 latencies of click-induced auditory-evoked potentials. Perceptuomotor processing speed and executive functioning were measured behaviorally using the Connections Test. Compared to younger adults, older adults exhibited poorer time-compressed speech identification and slower perceptuomotor processing. Executive functioning, P1 latency, and N1 latency did not differ between age groups. Time-compressed speech identification was independently predicted by P1 latency, perceptuomotor processing speed, and executive functioning in younger and older listeners. Results of model testing suggested that declines in perceptuomotor processing speed mediated age-group differences in time-compressed speech identification. The current investigation joins a growing body of literature suggesting that the processing of temporally distorted speech is impacted by lower-level auditory neural processing and higher-level perceptuomotor and executive processes.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6uLeH

Clinical features of poorly differentiated thyroid papillary carcinoma

To investigate the clinical feature of the poorly differentiated thyroid papillary carcinoma.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2qUxiEH

A New Peanut Allergy Drug Could Be a Promising Treatment for Children

A new drug could become the first-ever protective treatment for the more than one million children in the U.S. who suffer from peanut allergies. In a phase-three trial, the results of which were published in the New England Journal of Medicine, the peanut-derived drug AR101 helped some children with severe peanut allergies tolerate the equivalent of two peanut kernels without serious side effects. Prior to taking the drug, none of these children could safely ingest more than the equivalent of one-tenth of a kernel. AR101, which is manufactured by Aimmune Therapeutics (the company also designed and funded the study), delivers a controlled daily dose of peanut protein, with the goal of building tolerance over time and minimizing the dangers of accidental peanut exposure. Tolerance-building i...

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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PDS3mQ

Experimental treatment may desensitize allergic kids to peanuts

(Reuters Health) - Peanut allergy can be life-threatening, but a new study suggests that peanut protein itself can be used to slowly dial down the intensity of the allergic reaction. (Source: Reuters: Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A8GbOX

Jay Robb Enterprises Issues Allergy Alert on Undeclared Milk Allergen in Unflavored Egg White Protein

Jay Robb Enterprises is recalling Jay Robb Unflavored Egg White Protein Product, manufactured by Agropur MSI, LLC of La Crosse, Wisconsin, because it may contain undeclared milk allergen. People who have an allergy or severe sensitivity to milk run the risk of serious or life-threatening allergic reaction if they consume these products. (Source: Food and Drug Administration)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QWrSEC

New Therapy A Breakthrough Against Peanut Allergy?

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PFGSKk

Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users

Abstract

Poor spectral resolution contributes to the difficulties experienced by cochlear implant (CI) users when listening to speech in noise. However, correlations between measures of spectral resolution and speech perception in noise have not always been found to be robust. It may be that the relationship between spectral resolution and speech perception in noise becomes clearer in conditions where the speech and noise are not spectrally matched, so that improved spectral resolution can assist in separating the speech from the masker. To test this prediction, speech intelligibility was measured with noise or tone maskers that were presented either in the same spectral channels as the speech or in interleaved spectral channels. Spectral resolution was estimated via a spectral ripple discrimination task. Results from vocoder simulations in normal-hearing listeners showed increasing differences in speech intelligibility between spectrally overlapped and interleaved maskers as well as improved spectral ripple discrimination with increasing spectral resolution. However, no clear differences were observed in CI users between performance with spectrally interleaved and overlapped maskers, or between tone and noise maskers. The results suggest that spectral resolution in current CIs is too poor to take advantage of the spectral separation produced by spectrally interleaved speech and maskers. Overall, the spectrally interleaved and tonal maskers produce a much larger difference in performance between normal-hearing listeners and CI users than do traditional speech-in-noise measures, and thus provide a more sensitive test of speech perception abilities for current and future implantable devices.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tpb2zH

Time-Compressed Speech Identification Is Predicted by Auditory Neural Processing, Perceptuomotor Speed, and Executive Functioning in Younger and Older Listeners

Abstract

Older adults typically have difficulty identifying speech that is temporally distorted, such as reverberant, accented, time-compressed, or interrupted speech. These difficulties occur even when hearing thresholds fall within a normal range. Auditory neural processing speed, which we have previously found to predict auditory temporal processing (auditory gap detection), may interfere with the ability to recognize phonetic features as they rapidly unfold over time in spoken speech. Further, declines in perceptuomotor processing speed and executive functioning may interfere with the ability to track, access, and process information. The current investigation examined the extent to which age-related differences in time-compressed speech identification were predicted by auditory neural processing speed, perceptuomotor processing speed, and executive functioning. Groups of normal-hearing (up to 3000 Hz) younger and older adults identified 40, 50, and 60 % time-compressed sentences. Auditory neural processing speed was defined as the P1 and N1 latencies of click-induced auditory-evoked potentials. Perceptuomotor processing speed and executive functioning were measured behaviorally using the Connections Test. Compared to younger adults, older adults exhibited poorer time-compressed speech identification and slower perceptuomotor processing. Executive functioning, P1 latency, and N1 latency did not differ between age groups. Time-compressed speech identification was independently predicted by P1 latency, perceptuomotor processing speed, and executive functioning in younger and older listeners. Results of model testing suggested that declines in perceptuomotor processing speed mediated age-group differences in time-compressed speech identification. The current investigation joins a growing body of literature suggesting that the processing of temporally distorted speech is impacted by lower-level auditory neural processing and higher-level perceptuomotor and executive processes.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6uLeH

A New Peanut Allergy Drug Could Be a Promising Treatment for Children

A new drug could become the first-ever protective treatment for the more than one million children in the U.S. who suffer from peanut allergies. In a phase-three trial, the results of which were published in the New England Journal of Medicine, the peanut-derived drug AR101 helped some children with severe peanut allergies tolerate the equivalent of two peanut kernels without serious side effects. Prior to taking the drug, none of these children could safely ingest more than the equivalent of one-tenth of a kernel. AR101, which is manufactured by Aimmune Therapeutics (the company also designed and funded the study), delivers a controlled daily dose of peanut protein, with the goal of building tolerance over time and minimizing the dangers of accidental peanut exposure. Tolerance-building i...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PDS3mQ

New Peanut Allergy Drug Shows Unprecedented Success New Peanut Allergy Drug Shows Unprecedented Success

Two-thirds of children and adolescents could tolerate two peanuts after a year of immunotherapy, results from the phase 3 PALISADE study show, which could protect them from accidental ingestion.Medscape Medical News (Source: Medscape Medical News Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TpQiYJ

Experimental treatment may desensitize allergic kids to peanuts

(Reuters Health) - Peanut allergy can be life-threatening, but a new study suggests that peanut protein itself can be used to slowly dial down the intensity of the allergic reaction. (Source: Reuters: Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A8GbOX

Jay Robb Enterprises Issues Allergy Alert on Undeclared Milk Allergen in Unflavored Egg White Protein

Jay Robb Enterprises is recalling Jay Robb Unflavored Egg White Protein Product, manufactured by Agropur MSI, LLC of La Crosse, Wisconsin, because it may contain undeclared milk allergen. People who have an allergy or severe sensitivity to milk run the risk of serious or life-threatening allergic reaction if they consume these products. (Source: Food and Drug Administration)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QWrSEC

Medical News Today: 'Breakthrough' treatment for peanut allergy awaits FDA check

Millions of people live with peanut allergy, for which there is currently no available treatment. Thanks to a new study, though, this may soon change. (Source: Health News from Medical News Today)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A3F17z

New Therapy A Breakthrough Against Peanut Allergy?

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PFGSKk

Speech Perception with Spectrally Non-overlapping Maskers as Measure of Spectral Resolution in Cochlear Implant Users

Abstract

Poor spectral resolution contributes to the difficulties experienced by cochlear implant (CI) users when listening to speech in noise. However, correlations between measures of spectral resolution and speech perception in noise have not always been found to be robust. It may be that the relationship between spectral resolution and speech perception in noise becomes clearer in conditions where the speech and noise are not spectrally matched, so that improved spectral resolution can assist in separating the speech from the masker. To test this prediction, speech intelligibility was measured with noise or tone maskers that were presented either in the same spectral channels as the speech or in interleaved spectral channels. Spectral resolution was estimated via a spectral ripple discrimination task. Results from vocoder simulations in normal-hearing listeners showed increasing differences in speech intelligibility between spectrally overlapped and interleaved maskers as well as improved spectral ripple discrimination with increasing spectral resolution. However, no clear differences were observed in CI users between performance with spectrally interleaved and overlapped maskers, or between tone and noise maskers. The results suggest that spectral resolution in current CIs is too poor to take advantage of the spectral separation produced by spectrally interleaved speech and maskers. Overall, the spectrally interleaved and tonal maskers produce a much larger difference in performance between normal-hearing listeners and CI users than do traditional speech-in-noise measures, and thus provide a more sensitive test of speech perception abilities for current and future implantable devices.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Tpb2zH

Time-Compressed Speech Identification Is Predicted by Auditory Neural Processing, Perceptuomotor Speed, and Executive Functioning in Younger and Older Listeners

Abstract

Older adults typically have difficulty identifying speech that is temporally distorted, such as reverberant, accented, time-compressed, or interrupted speech. These difficulties occur even when hearing thresholds fall within a normal range. Auditory neural processing speed, which we have previously found to predict auditory temporal processing (auditory gap detection), may interfere with the ability to recognize phonetic features as they rapidly unfold over time in spoken speech. Further, declines in perceptuomotor processing speed and executive functioning may interfere with the ability to track, access, and process information. The current investigation examined the extent to which age-related differences in time-compressed speech identification were predicted by auditory neural processing speed, perceptuomotor processing speed, and executive functioning. Groups of normal-hearing (up to 3000 Hz) younger and older adults identified 40, 50, and 60 % time-compressed sentences. Auditory neural processing speed was defined as the P1 and N1 latencies of click-induced auditory-evoked potentials. Perceptuomotor processing speed and executive functioning were measured behaviorally using the Connections Test. Compared to younger adults, older adults exhibited poorer time-compressed speech identification and slower perceptuomotor processing. Executive functioning, P1 latency, and N1 latency did not differ between age groups. Time-compressed speech identification was independently predicted by P1 latency, perceptuomotor processing speed, and executive functioning in younger and older listeners. Results of model testing suggested that declines in perceptuomotor processing speed mediated age-group differences in time-compressed speech identification. The current investigation joins a growing body of literature suggesting that the processing of temporally distorted speech is impacted by lower-level auditory neural processing and higher-level perceptuomotor and executive processes.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A6uLeH

A New Peanut Allergy Drug Could Be a Promising Treatment for Children

A new drug could become the first-ever protective treatment for the more than one million children in the U.S. who suffer from peanut allergies. In a phase-three trial, the results of which were published in the New England Journal of Medicine, the peanut-derived drug AR101 helped some children with severe peanut allergies tolerate the equivalent of two peanut kernels without serious side effects. Prior to taking the drug, none of these children could safely ingest more than the equivalent of one-tenth of a kernel. AR101, which is manufactured by Aimmune Therapeutics (the company also designed and funded the study), delivers a controlled daily dose of peanut protein, with the goal of building tolerance over time and minimizing the dangers of accidental peanut exposure. Tolerance-building i...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PDS3mQ

New Peanut Allergy Drug Shows Unprecedented Success New Peanut Allergy Drug Shows Unprecedented Success

Two-thirds of children and adolescents could tolerate two peanuts after a year of immunotherapy, results from the phase 3 PALISADE study show, which could protect them from accidental ingestion.Medscape Medical News (Source: Medscape Medical News Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TpQiYJ

Experimental treatment may desensitize allergic kids to peanuts

(Reuters Health) - Peanut allergy can be life-threatening, but a new study suggests that peanut protein itself can be used to slowly dial down the intensity of the allergic reaction. (Source: Reuters: Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A8GbOX

Jay Robb Enterprises Issues Allergy Alert on Undeclared Milk Allergen in Unflavored Egg White Protein

Jay Robb Enterprises is recalling Jay Robb Unflavored Egg White Protein Product, manufactured by Agropur MSI, LLC of La Crosse, Wisconsin, because it may contain undeclared milk allergen. People who have an allergy or severe sensitivity to milk run the risk of serious or life-threatening allergic reaction if they consume these products. (Source: Food and Drug Administration)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QWrSEC

New Therapy A Breakthrough Against Peanut Allergy?

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PFGSKk

A New Peanut Allergy Drug Could Be a Promising Treatment for Children

A new drug could become the first-ever protective treatment for the more than one million children in the U.S. who suffer from peanut allergies. In a phase-three trial, the results of which were published in the New England Journal of Medicine, the peanut-derived drug AR101 helped some children with severe peanut allergies tolerate the equivalent of two peanut kernels without serious side effects. Prior to taking the drug, none of these children could safely ingest more than the equivalent of one-tenth of a kernel. AR101, which is manufactured by Aimmune Therapeutics (the company also designed and funded the study), delivers a controlled daily dose of peanut protein, with the goal of building tolerance over time and minimizing the dangers of accidental peanut exposure. Tolerance-building i...

MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PDS3mQ

New Peanut Allergy Drug Shows Unprecedented Success New Peanut Allergy Drug Shows Unprecedented Success

Two-thirds of children and adolescents could tolerate two peanuts after a year of immunotherapy, results from the phase 3 PALISADE study show, which could protect them from accidental ingestion.Medscape Medical News (Source: Medscape Medical News Headlines)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2TpQiYJ

Experimental treatment may desensitize allergic kids to peanuts

(Reuters Health) - Peanut allergy can be life-threatening, but a new study suggests that peanut protein itself can be used to slowly dial down the intensity of the allergic reaction. (Source: Reuters: Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A8GbOX

Medical News Today: 'Breakthrough' treatment for peanut allergy awaits FDA check

Millions of people live with peanut allergy, for which there is currently no available treatment. Thanks to a new study, though, this may soon change. (Source: Health News from Medical News Today)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2A3F17z

New Therapy A Breakthrough Against Peanut Allergy?

After nine to 12 months of treatment, two-thirds of people in a new study were able to tolerate the equivalent of two peanuts per day, and half the patients tolerated the equivalent of four peanuts. (Source: WebMD Health)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PFGSKk

The role of the audiologist –phoniatrician in performing the dynamic endoscopic study of swallowing. Position statement of the Italian study group on dysphagia (GISD)*

. (Source: Hearing, Balance and Communication)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RXarUg

The frequency-following response (FFR) to speech stimuli: A  normative dataset in healthy newborns.

The frequency-following response (FFR) to speech stimuli: A normative dataset in healthy newborns. Hear Res. 2018 Nov 09;371:28-39 Authors: Ribas-Prats T, Almeida L, Costa-Faidella J, Plana M, Corral MJ, Gómez-Roig MD, Escera C Abstract The Frequency-Following Response (FFR) is a neurophonic auditory evoked potential that reflects the efficient encoding of speech sounds and is disrupted in a range of speech and language disorders. This raises the possibility to use it as a potential biomarker for literacy impairment. However, reference values for comparison with the normal population are not yet established. The present study pursues the collection of a normative database depicting the standard variability of the newborn FFR. FFRs were recorded to /da/ and /ga/ sylla...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DNFTl1

The role of the audiologist –phoniatrician in performing the dynamic endoscopic study of swallowing. Position statement of the Italian study group on dysphagia (GISD)*

. (Source: Hearing, Balance and Communication)

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2RXarUg

The frequency-following response (FFR) to speech stimuli: A  normative dataset in healthy newborns.

The frequency-following response (FFR) to speech stimuli: A normative dataset in healthy newborns. Hear Res. 2018 Nov 09;371:28-39 Authors: Ribas-Prats T, Almeida L, Costa-Faidella J, Plana M, Corral MJ, Gómez-Roig MD, Escera C Abstract The Frequency-Following Response (FFR) is a neurophonic auditory evoked potential that reflects the efficient encoding of speech sounds and is disrupted in a range of speech and language disorders. This raises the possibility to use it as a potential biomarker for literacy impairment. However, reference values for comparison with the normal population are not yet established. The present study pursues the collection of a normative database depicting the standard variability of the newborn FFR. FFRs were recorded to /da/ and /ga/ sylla...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DNFTl1

Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location

Abstract

Purpose

The mechanisms of cerebral aneurysm rupture are not fully understood. We analyzed the associations of hemodynamics, morphology, and patient age and gender with aneurysm rupture stratifying by location.

Methods

Using image-based models, 20 hemodynamic and 17 morphological parameters were compared in 1931 ruptured and unruptured aneurysms with univariate logistic regression. Rupture rates were compared between males and females as well as younger and older patients and bifurcation versus sidewall aneurysms for different aneurysm locations. Subsequently, associations between hemodynamics and morphology and patient as well as aneurysm characteristics were analyzed for aneurysms at five locations.

Results

Compared to unruptured aneurysms, ruptured aneurysms were characterized by a more irregular shape and were exposed to a more adverse hemodynamic environment described by faster flow, higher wall shear stress, more oscillatory shear, and more unstable and complex flows. These associations with rupture status were consistent for different aneurysm locations. Rupture rates were significantly higher in males at the internal carotid artery (ICA) bifurcation, ophthalmic ICA, and the middle cerebral artery (MCA) bifurcation. At the anterior communicating artery (ACOM) and MCA bifurcation, they were significantly higher for younger patients. Bifurcation aneurysms had significantly larger rupture rates at the MCA and posterior communicating artery (PCOM). In these groups with higher rupture rates, aneurysms were characterized by adverse hemodynamics and more complex shapes.

Conclusion

Hemodynamic and morphological differences between ruptured and unruptured aneurysms are consistent across locations. Adverse morphology and hemodynamics are related to rupture as well as younger age, male gender, and bifurcation aneurysms.



from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OSA8Um

Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location

Abstract

Purpose

The mechanisms of cerebral aneurysm rupture are not fully understood. We analyzed the associations of hemodynamics, morphology, and patient age and gender with aneurysm rupture stratifying by location.

Methods

Using image-based models, 20 hemodynamic and 17 morphological parameters were compared in 1931 ruptured and unruptured aneurysms with univariate logistic regression. Rupture rates were compared between males and females as well as younger and older patients and bifurcation versus sidewall aneurysms for different aneurysm locations. Subsequently, associations between hemodynamics and morphology and patient as well as aneurysm characteristics were analyzed for aneurysms at five locations.

Results

Compared to unruptured aneurysms, ruptured aneurysms were characterized by a more irregular shape and were exposed to a more adverse hemodynamic environment described by faster flow, higher wall shear stress, more oscillatory shear, and more unstable and complex flows. These associations with rupture status were consistent for different aneurysm locations. Rupture rates were significantly higher in males at the internal carotid artery (ICA) bifurcation, ophthalmic ICA, and the middle cerebral artery (MCA) bifurcation. At the anterior communicating artery (ACOM) and MCA bifurcation, they were significantly higher for younger patients. Bifurcation aneurysms had significantly larger rupture rates at the MCA and posterior communicating artery (PCOM). In these groups with higher rupture rates, aneurysms were characterized by adverse hemodynamics and more complex shapes.

Conclusion

Hemodynamic and morphological differences between ruptured and unruptured aneurysms are consistent across locations. Adverse morphology and hemodynamics are related to rupture as well as younger age, male gender, and bifurcation aneurysms.



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Effect of Age, Sex, Bolus Volume, and Bolus Consistency on Whiteout Duration in Healthy Subjects During FEES

AbstractOne of the major limitations of the fiberoptic endoscopic evaluation of swallowing (FEES) is related to the challenging application of temporal measures. Among them, Whiteout (WO) is due to pharyngeal and tongue base contraction and might be used as an estimation of the pharyngeal phase duration. The aims of this study were to evaluate the inter- and intrarater reliability of WO duration and to appraise the effects of age, sex, volume, and texture of the boluses on this temporal measurement. A total of 30 healthy volunteers were recruited. According to their age, the subjects were grouped into three different age groups. Each of them underwent FEES examination with different textures (liquid, semisolid, and solid) and volumes. FEES examinations were video recorded, processed with t...

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Effect of Age, Sex, Bolus Volume, and Bolus Consistency on Whiteout Duration in Healthy Subjects During FEES

AbstractOne of the major limitations of the fiberoptic endoscopic evaluation of swallowing (FEES) is related to the challenging application of temporal measures. Among them, Whiteout (WO) is due to pharyngeal and tongue base contraction and might be used as an estimation of the pharyngeal phase duration. The aims of this study were to evaluate the inter- and intrarater reliability of WO duration and to appraise the effects of age, sex, volume, and texture of the boluses on this temporal measurement. A total of 30 healthy volunteers were recruited. According to their age, the subjects were grouped into three different age groups. Each of them underwent FEES examination with different textures (liquid, semisolid, and solid) and volumes. FEES examinations were video recorded, processed with t...

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In reply: a call for feedback on postoperative care: do we need an automated tool?



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In reply: a call for feedback on postoperative care: do we need an automated tool?



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The Collagenase of the Bacterium Clostridium histolyticum in the Treatment of Irradiation-Induced Capsular Contracture

Abstract

Background

Irradiation therapy is an important pillar in the treatment of breast cancer. However, it can trigger capsular fibrosis, the most significant complication of implant-based breast reconstruction. As collagen is the main component of fibrotic capsules, the collagenase of the bacterium Clostridium histolyticum poses a potential treatment option for this pathological condition.

Methods

Thirty-six rats received miniature silicone implants on their backs. On day 1, the implant sites of two groups were irradiated with 10 Gy. On day 120, one irradiated group received collagenase injections into the implant pockets (n = 12). Non-irradiated (n = 12) and irradiated capsules (n = 12) were injected with plain solvent solution serving as controls. Data were analyzed by means of in vivo imaging, histology, immunohistochemistry and gene expression analysis.

Results

Compared with both controls, the injection of collagenase led to significantly thinner capsules. This was verified by in vivo imaging and histology. Although irradiation provoked alterations in capsule collagen structure and vessel wall thickness, the application of collagenase resulted in a significant reduction of collagen density. This was accompanied by an up-regulation of VEGF-A gene expression. Of note, hematoma formation inside the implant pocket occurred in two cases after collagenase injection.

Conclusions

The collagenase of the bacterium Clostridium histolyticum is effective in degrading irradiation-induced capsular fibrosis around silicone implants. Hematoma formation occurred most likely because of irradiation-induced alterations in vessel wall architecture and capsule vascularization. Further studies need to be performed to address the clinical safety of this novel treatment option.



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Galactocele After Aesthetic Breast Augmentation with Silicone Implants: An Uncommon Presentation

Abstract

Background

Breast augmentation is one of the most frequently performed esthetic operations. Galactorrhea and galactocele formation are both very rare complications. The real cause still remains unknown, but various risk factors have been well reported in the literature. This report concerns a case of postoperative galactocele following bilateral breast augmentation via the inframammary approach with dual-plane insertion of implants, which is usually considered a protective approach in terms of risk factors for induction of postoperative galactorrhea.

Methods

The patient had no significant surgical, gynecological or medical history, including galactorrhea or hyperprolactinemia, and did not present any chest wall abnormalities. There has been no use of oral contraceptives or any other drugs. After the surgical procedure, the patient presented with infection-like symptoms, for which galactorrhea or galactocele was initially not considered, mainly for the absence of specific risk factors.

Results

After antibiotic and bromocriptine therapy, her breast returned to normal, with no pain, inflammation, enlargement or esthetic alterations. After 6 months of follow-up, the patient did not present any abnormality and she was satisfied with the result.

Conclusion

With our report, we want to underline that galactorrhea and galactocele cannot be ruled out, even in patients with no risk factors and with procedures considered as "protective." With a fast diagnosis and a specific therapy, implants and final result can be rescued.

Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.



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