Getty Images ... My wife has been asking me to get my hearing checked for the past 10 years. ... I understand her frustration; I fail to respond to her voice a few times each day — and no, I'm not ... (Source: AARP.org News)
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An individualized CT-guided approach to programming cochlear implants significantly...Read more on AuntMinnie.comRelated Reading: Flat-panel CT finds early signs of bone damage in anorexics Flat-panel CT falls short in cerebral bleed assessment Flat-panel detector CT bests MDCT in the skull base Flat-panel detectors cut radiation dose in angiography, pediatric chest x-rays (Source: AuntMinnie.com Headlines)
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Getty Images ... My wife has been asking me to get my hearing checked for the past 10 years. ... I understand her frustration; I fail to respond to her voice a few times each day — and no, I'm not ... (Source: AARP.org News)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
An individualized CT-guided approach to programming cochlear implants significantly...Read more on AuntMinnie.comRelated Reading: Flat-panel CT finds early signs of bone damage in anorexics Flat-panel CT falls short in cerebral bleed assessment Flat-panel detector CT bests MDCT in the skull base Flat-panel detectors cut radiation dose in angiography, pediatric chest x-rays (Source: AuntMinnie.com Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BoIxLI
Most epidemiologic studies reporting prevalence of allergic rhinitis (AR) and nonallergic rhinitis (NAR) have assessed solely self-reported prevalence, without confirmation by objective measures. Furthermore, ...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BqTegH
Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is an autosomal dominant disease resulting in random and unpredictable attacks of swelling. The swelling in C1-INH-HAE is a result of impaired ...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2KvFDI5
Most epidemiologic studies reporting prevalence of allergic rhinitis (AR) and nonallergic rhinitis (NAR) have assessed solely self-reported prevalence, without confirmation by objective measures. Furthermore, ...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BqTegH
Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is an autosomal dominant disease resulting in random and unpredictable attacks of swelling. The swelling in C1-INH-HAE is a result of impaired ...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2KvFDI5
In conclusion, LA involving the contralateral CBT is associated with dysphagia in patients with unilateral CR infarction involving the CBT. (Source: Dysphagia)
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In conclusion, LA involving the contralateral CBT is associated with dysphagia in patients with unilateral CR infarction involving the CBT. (Source: Dysphagia)
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If you're interested in joining an active community of clinicians, educators, researchers, and students collaborating to enhance communication outcomes of children who are deaf and hard of hearing or who have other auditory/vestibular-related disorders, then SIG 9 is for you. Read on for more from James Mahshie. When did you join your SIG—and what made you want to join? SIG 9 was an obvious way to learn more about hearing and hearing loss in children, particularly because my research focuses on perception and production abilities of children with cochlear implants. I joined SIG 9 in 2012 and decided to run for the coordinating committee in 2014 as a way to get more involved with ASHA. I've now been on the committee for four years and became the coordinator in 2018. How has your i...
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Health-related quality of life (HRQoL) is a key metric to understand the impact of stroke from patients' perspective. Yet HRQoL is not readily measured in clinical practice. This study aims to investigate the ...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Qc3mSB
If you're interested in joining an active community of clinicians, educators, researchers, and students collaborating to enhance communication outcomes of children who are deaf and hard of hearing or who have other auditory/vestibular-related disorders, then SIG 9 is for you. Read on for more from James Mahshie. When did you join your SIG—and what made you want to join? SIG 9 was an obvious way to learn more about hearing and hearing loss in children, particularly because my research focuses on perception and production abilities of children with cochlear implants. I joined SIG 9 in 2012 and decided to run for the coordinating committee in 2014 as a way to get more involved with ASHA. I've now been on the committee for four years and became the coordinator in 2018. How has your i...
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Health-related quality of life (HRQoL) is a key metric to understand the impact of stroke from patients' perspective. Yet HRQoL is not readily measured in clinical practice. This study aims to investigate the ...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Qc3mSB
If you're interested in joining an active community of clinicians, educators, researchers, and students collaborating to enhance communication outcomes of children who are deaf and hard of hearing or who have other auditory/vestibular-related disorders, then SIG 9 is for you. Read on for more from James Mahshie. When did you join your SIG—and what made you want to join? SIG 9 was an obvious way to learn more about hearing and hearing loss in children, particularly because my research focuses on perception and production abilities of children with cochlear implants. I joined SIG 9 in 2012 and decided to run for the coordinating committee in 2014 as a way to get more involved with ASHA. I've now been on the committee for four years and became the coordinator in 2018. How has your i...
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Accessing folk knowledge from small-scale fishers is an affordable and reliable approach to understand the dynamic and diversity of shark species worldwide, especially of those eventually caught. In this conte...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ty7QSr
If you're interested in joining an active community of clinicians, educators, researchers, and students collaborating to enhance communication outcomes of children who are deaf and hard of hearing or who have other auditory/vestibular-related disorders, then SIG 9 is for you. Read on for more from James Mahshie. When did you join your SIG—and what made you want to join? SIG 9 was an obvious way to learn more about hearing and hearing loss in children, particularly because my research focuses on perception and production abilities of children with cochlear implants. I joined SIG 9 in 2012 and decided to run for the coordinating committee in 2014 as a way to get more involved with ASHA. I've now been on the committee for four years and became the coordinator in 2018. How has your i...
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Accessing folk knowledge from small-scale fishers is an affordable and reliable approach to understand the dynamic and diversity of shark species worldwide, especially of those eventually caught. In this conte...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Ty7QSr
Nodular lesions of the thyroid gland, including papillary thyroid carcinoma (PTC), may be difficult to diagnose by imaging, such as in ultrasonic echo testing, or by needle biopsy. Definitive diagnosis is made...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S702p7
Nodular lesions of the thyroid gland, including papillary thyroid carcinoma (PTC), may be difficult to diagnose by imaging, such as in ultrasonic echo testing, or by needle biopsy. Definitive diagnosis is made...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S702p7
If you're interested in joining an active community of clinicians, educators, researchers, and students collaborating to enhance communication outcomes of children who are deaf and hard of hearing or who have other auditory/vestibular-related disorders, then SIG 9 is for you. Read on for more from James Mahshie. When did you join your SIG—and what made you want to join? SIG 9 was an obvious way to learn more about hearing and hearing loss in children, particularly because my research focuses on perception and production abilities of children with cochlear implants. I joined SIG 9 in 2012 and decided to run for the coordinating committee in 2014 as a way to get more involved with ASHA. I've now been on the committee for four years and became the coordinator in 2018. How has your i...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Kp8Jss
If you're interested in joining an active community of clinicians, educators, researchers, and students collaborating to enhance communication outcomes of children who are deaf and hard of hearing or who have other auditory/vestibular-related disorders, then SIG 9 is for you. Read on for more from James Mahshie. When did you join your SIG—and what made you want to join? SIG 9 was an obvious way to learn more about hearing and hearing loss in children, particularly because my research focuses on perception and production abilities of children with cochlear implants. I joined SIG 9 in 2012 and decided to run for the coordinating committee in 2014 as a way to get more involved with ASHA. I've now been on the committee for four years and became the coordinator in 2018. How has your i...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Kp8Jss
Based on immunologic phenotypes underlying asthma, use of monoclonal antibody based therapies is becoming the new standard of care for severe, corticosteroid refractory clinical symptoms. Patients may qualify for one or more of these targeted treatments, based on clinical characteristics and approved indications. However, the statistics are not well characterized, particularly in the Canadian population.
The objective of this observational study was to identify and describe the proportion of patients with severe asthma who were eligible for targeting IgE, IL-5, or both pathways of immunomodulation. We reviewed a cross-sectional cohort of patients in a Canadian Allergy and Immunology referral practice. We also compared demographic and clinical characteristics of each group.
Of the 128 patients with severe asthma, 84 (66%) were eligible for omalizumab, 100 (78%) for mepolizumab, 52 (41%) for reslizumab, and 68 (53%) for benralizumab. Overlap in treatment eligibility varied; 68 (53%) patients were eligible for both omalizumab and mepolizumab, 47 (37%) were eligible for omalizumab and benralizumab, and 37 (29%) were eligible for all four medications. Patient demographics and clinical characteristics were similar, and levels of serum biomarkers varied based on locally approved prescribing criteria.
In this severe asthma population from a Canadian Allergist's practice, one-third of individuals qualified for all currently available biologics. 41–78% were eligible for at least one mAb. Patients were most likely to be eligible for mepolizumab. Objective assessments to determine asthma phenotype, along with further characterization of safety profiles will lead to further advances in asthma management.
Based on immunologic phenotypes underlying asthma, use of monoclonal antibody based therapies is becoming the new standard of care for severe, corticosteroid refractory clinical symptoms. Patients may qualify for one or more of these targeted treatments, based on clinical characteristics and approved indications. However, the statistics are not well characterized, particularly in the Canadian population.
The objective of this observational study was to identify and describe the proportion of patients with severe asthma who were eligible for targeting IgE, IL-5, or both pathways of immunomodulation. We reviewed a cross-sectional cohort of patients in a Canadian Allergy and Immunology referral practice. We also compared demographic and clinical characteristics of each group.
Of the 128 patients with severe asthma, 84 (66%) were eligible for omalizumab, 100 (78%) for mepolizumab, 52 (41%) for reslizumab, and 68 (53%) for benralizumab. Overlap in treatment eligibility varied; 68 (53%) patients were eligible for both omalizumab and mepolizumab, 47 (37%) were eligible for omalizumab and benralizumab, and 37 (29%) were eligible for all four medications. Patient demographics and clinical characteristics were similar, and levels of serum biomarkers varied based on locally approved prescribing criteria.
In this severe asthma population from a Canadian Allergist's practice, one-third of individuals qualified for all currently available biologics. 41–78% were eligible for at least one mAb. Patients were most likely to be eligible for mepolizumab. Objective assessments to determine asthma phenotype, along with further characterization of safety profiles will lead to further advances in asthma management.
Registration is open for the Clinical and Scientific Innovations for Oral and Maxillofacial Surgery (CSIOMS) conference being held April 26 to 28 in Rosemont, IL. The complimentary conference covers the latest in OMS research and innovations relevant to patient care.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R3iiQr
Registration is open for the Clinical and Scientific Innovations for Oral and Maxillofacial Surgery (CSIOMS) conference being held April 26 to 28 in Rosemont, IL. The complimentary conference covers the latest in OMS research and innovations relevant to patient care.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R3iiQr
A top U.S. Food and Drug Administration official testified on Monday that the agency has concerns about drugs made by compounding pharmacies and still sees problems with them six years after a fungal meningitis outbreak tied to a Massachusetts pharmacy killed 76 people.Reuters Health Information (Source: Medscape Allergy Headlines)
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This cohort study evaluates the association between image-based place-pitch mapping using flat-panel computed tomography with speech and pitch perception in individuals with cochlear implants. (Source: JAMA Otolaryngology - Head and Neck Surgery)
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Helios is a key transcriptional regulator of outer hair cell maturation, Published online: 21 November 2018; doi:10.1038/s41586-018-0728-4Ikzf2, which encodes the transcription factor Helios, is identified as a crucial regulator of gene expression in maturing cochlear outer hair cells, and overexpression of Ikzf2 in inner hair cells induces prestin expression and electromotility. (Source: Nature AOP)
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This cohort study evaluates the association between image-based place-pitch mapping using flat-panel computed tomography with speech and pitch perception in individuals with cochlear implants. (Source: JAMA Otolaryngology - Head and Neck Surgery)
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Helios is a key transcriptional regulator of outer hair cell maturation, Published online: 21 November 2018; doi:10.1038/s41586-018-0728-4Ikzf2, which encodes the transcription factor Helios, is identified as a crucial regulator of gene expression in maturing cochlear outer hair cells, and overexpression of Ikzf2 in inner hair cells induces prestin expression and electromotility. (Source: Nature AOP)
MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
A top U.S. Food and Drug Administration official testified on Monday that the agency has concerns about drugs made by compounding pharmacies and still sees problems with them six years after a fungal meningitis outbreak tied to a Massachusetts pharmacy killed 76 people.Reuters Health Information (Source: Medscape Allergy Headlines)
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Only last month Karen was celebrating after winning the teaching and learning support staff category at the National Association for Special Educational Needs' annual awards. The category is open to "anyone in a teaching and learning support role who has demonstrated commitment and excellent practice which has improved the outcomes for children and young people with special educational needs". Karen (pictured above) has worked at St Giles for almost 18 years and described the awards ceremony, held at London's Waldorf Hotel, as "a lovely evening. I met so many inspirational candidates. "It was an honour to be nominated and it was such a surprise when my name was called out. "I am passionate about giving children a voice and supporting them with their communication skills." K...
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FREE ACCESS through December 5, 2018.
Latest Impact Factor: 7.557
The Official Journal of: American Thyroid Association®
Read now:
Mutated Thyroid Hormone Transporter OATP1C1 Associates with Severe Brain Hypometabolism and Juvenile Neurodegeneration
Petter Strømme, Stefan Groeneweg, Elaine C. Lima de Souza, Chantal Zevenbergen, Anette Torgersbråten, Asbjørn Holmgren, Ebrar Gurcan, Marcel E. Meima, Robin P. Peeters, W. Edward Visser, Linda Høneren Johansson, Almira Babovic, Henrik Zetterberg, Heike Heuer, Eirik Frengen, Doriana Misceo, and Theo J. Visser
Metal Coordinated Poly-Zinc-Liothyronine Provides Stable Circulating Triiodothyronine Levels in Hypothyroid Rats
Rodrigo R. Da Conceição, Gustavo W. Fernandes, Tatiana L. Fonseca, Barbara M.L.C. Bocco, and Antonio C. Bianco
Response to Lenvatinib in Children with Papillary Thyroid Carcinoma
Priya Mahajan, Jonathan Dawrant, Albert Kheradpour, Norma M. Quintanilla, Monica E. Lopez, Robert C. Orth, Ioanna Athanassaki, and Rajkumar Venkatramani
Comprehensive Transcriptomic and Genomic Profiling of Subtypes of Follicular Variant of Papillary Thyroid Carcinoma
Young Shin Song, Jae-Kyung Won, Seong-Keun Yoo, Kyeong Cheon Jung, Min Joo Kim, Su-Jin Kim, Sun Wook Cho, Kyu Eun Lee, Ka Hee Yi, Jeong-Sun Seo, and Young Joo Park
Diagnostic Performance of Ultrasound-Based Risk-Stratification Systems for Thyroid Nodules: Comparison of the 2015 American Thyroid Association Guidelines with the 2016 Korean Thyroid Association/Korean Society of Thyroid Radiology and 2017 American Congress of Radiology Guidelines
Eun Ju Ha, Dong Gyu Na, Won-Jin Moon, Young Hen Lee, and Nami Choi
The post <i>Thyroid<sup>®</sup></i> High-Impact Articles appeared first on American Thyroid Association.
A top U.S. Food and Drug Administration official testified on Monday that the agency has concerns about drugs made by compounding pharmacies and still sees problems with them six years after a fungal meningitis outbreak tied to a Massachusetts pharmacy killed 76 people.Reuters Health Information (Source: Medscape Allergy Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Only last month Karen was celebrating after winning the teaching and learning support staff category at the National Association for Special Educational Needs' annual awards. The category is open to "anyone in a teaching and learning support role who has demonstrated commitment and excellent practice which has improved the outcomes for children and young people with special educational needs". Karen (pictured above) has worked at St Giles for almost 18 years and described the awards ceremony, held at London's Waldorf Hotel, as "a lovely evening. I met so many inspirational candidates. "It was an honour to be nominated and it was such a surprise when my name was called out. "I am passionate about giving children a voice and supporting them with their communication skills." K...
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Registration is open for the Clinical and Scientific Innovations for Oral and Maxillofacial Surgery (CSIOMS) conference being held April 26 to 28 in Rosemont, IL. The complimentary conference covers the latest in OMS research and innovations relevant to patient care.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R3iiQr
Registration is open for the Clinical and Scientific Innovations for Oral and Maxillofacial Surgery (CSIOMS) conference being held April 26 to 28 in Rosemont, IL. The complimentary conference covers the latest in OMS research and innovations relevant to patient care.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R3iiQr
A 61-year-old woman who lost her nose, upper lip, and most of her midface bony structures due to cancer 20 years ago underwent advanced surgical reconstruction. This patient had previously undergone multiple reconstructive surgeries that failed to satisfactorily restore her nose. Therefore, a multi-stage reconstruction was performed to recreate a complete nose and increase her upper lip length. Due to a lack of sufficient facial bone and nasal supporting structures, the reconstruction was extremely challenging.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R0QewN
A 61-year-old woman who lost her nose, upper lip, and most of her midface bony structures due to cancer 20 years ago underwent advanced surgical reconstruction. This patient had previously undergone multiple reconstructive surgeries that failed to satisfactorily restore her nose. Therefore, a multi-stage reconstruction was performed to recreate a complete nose and increase her upper lip length. Due to a lack of sufficient facial bone and nasal supporting structures, the reconstruction was extremely challenging.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R0QewN
FREE ACCESS through December 5, 2018.
Latest Impact Factor: 7.557
The Official Journal of: American Thyroid Association®
Read now:
Mutated Thyroid Hormone Transporter OATP1C1 Associates with Severe Brain Hypometabolism and Juvenile Neurodegeneration
Petter Strømme, Stefan Groeneweg, Elaine C. Lima de Souza, Chantal Zevenbergen, Anette Torgersbråten, Asbjørn Holmgren, Ebrar Gurcan, Marcel E. Meima, Robin P. Peeters, W. Edward Visser, Linda Høneren Johansson, Almira Babovic, Henrik Zetterberg, Heike Heuer, Eirik Frengen, Doriana Misceo, and Theo J. Visser
Metal Coordinated Poly-Zinc-Liothyronine Provides Stable Circulating Triiodothyronine Levels in Hypothyroid Rats
Rodrigo R. Da Conceição, Gustavo W. Fernandes, Tatiana L. Fonseca, Barbara M.L.C. Bocco, and Antonio C. Bianco
Response to Lenvatinib in Children with Papillary Thyroid Carcinoma
Priya Mahajan, Jonathan Dawrant, Albert Kheradpour, Norma M. Quintanilla, Monica E. Lopez, Robert C. Orth, Ioanna Athanassaki, and Rajkumar Venkatramani
Comprehensive Transcriptomic and Genomic Profiling of Subtypes of Follicular Variant of Papillary Thyroid Carcinoma
Young Shin Song, Jae-Kyung Won, Seong-Keun Yoo, Kyeong Cheon Jung, Min Joo Kim, Su-Jin Kim, Sun Wook Cho, Kyu Eun Lee, Ka Hee Yi, Jeong-Sun Seo, and Young Joo Park
Diagnostic Performance of Ultrasound-Based Risk-Stratification Systems for Thyroid Nodules: Comparison of the 2015 American Thyroid Association Guidelines with the 2016 Korean Thyroid Association/Korean Society of Thyroid Radiology and 2017 American Congress of Radiology Guidelines
Eun Ju Ha, Dong Gyu Na, Won-Jin Moon, Young Hen Lee, and Nami Choi
The post <i>Thyroid<sup>®</sup></i> High-Impact Articles appeared first on American Thyroid Association.
FREE ACCESS through December 5, 2018.
Latest Impact Factor: 7.557
The Official Journal of: American Thyroid Association®
Read now:
Mutated Thyroid Hormone Transporter OATP1C1 Associates with Severe Brain Hypometabolism and Juvenile Neurodegeneration
Petter Strømme, Stefan Groeneweg, Elaine C. Lima de Souza, Chantal Zevenbergen, Anette Torgersbråten, Asbjørn Holmgren, Ebrar Gurcan, Marcel E. Meima, Robin P. Peeters, W. Edward Visser, Linda Høneren Johansson, Almira Babovic, Henrik Zetterberg, Heike Heuer, Eirik Frengen, Doriana Misceo, and Theo J. Visser
Metal Coordinated Poly-Zinc-Liothyronine Provides Stable Circulating Triiodothyronine Levels in Hypothyroid Rats
Rodrigo R. Da Conceição, Gustavo W. Fernandes, Tatiana L. Fonseca, Barbara M.L.C. Bocco, and Antonio C. Bianco
Response to Lenvatinib in Children with Papillary Thyroid Carcinoma
Priya Mahajan, Jonathan Dawrant, Albert Kheradpour, Norma M. Quintanilla, Monica E. Lopez, Robert C. Orth, Ioanna Athanassaki, and Rajkumar Venkatramani
Comprehensive Transcriptomic and Genomic Profiling of Subtypes of Follicular Variant of Papillary Thyroid Carcinoma
Young Shin Song, Jae-Kyung Won, Seong-Keun Yoo, Kyeong Cheon Jung, Min Joo Kim, Su-Jin Kim, Sun Wook Cho, Kyu Eun Lee, Ka Hee Yi, Jeong-Sun Seo, and Young Joo Park
Diagnostic Performance of Ultrasound-Based Risk-Stratification Systems for Thyroid Nodules: Comparison of the 2015 American Thyroid Association Guidelines with the 2016 Korean Thyroid Association/Korean Society of Thyroid Radiology and 2017 American Congress of Radiology Guidelines
Eun Ju Ha, Dong Gyu Na, Won-Jin Moon, Young Hen Lee, and Nami Choi
The post <i>Thyroid<sup>®</sup></i> High-Impact Articles appeared first on American Thyroid Association.
Only last month Karen was celebrating after winning the teaching and learning support staff category at the National Association for Special Educational Needs' annual awards. The category is open to "anyone in a teaching and learning support role who has demonstrated commitment and excellent practice which has improved the outcomes for children and young people with special educational needs". Karen (pictured above) has worked at St Giles for almost 18 years and described the awards ceremony, held at London's Waldorf Hotel, as "a lovely evening. I met so many inspirational candidates. "It was an honour to be nominated and it was such a surprise when my name was called out. "I am passionate about giving children a voice and supporting them with their communication skills." K...
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Only last month Karen was celebrating after winning the teaching and learning support staff category at the National Association for Special Educational Needs' annual awards. The category is open to "anyone in a teaching and learning support role who has demonstrated commitment and excellent practice which has improved the outcomes for children and young people with special educational needs". Karen (pictured above) has worked at St Giles for almost 18 years and described the awards ceremony, held at London's Waldorf Hotel, as "a lovely evening. I met so many inspirational candidates. "It was an honour to be nominated and it was such a surprise when my name was called out. "I am passionate about giving children a voice and supporting them with their communication skills." K...
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
A top U.S. Food and Drug Administration official testified on Monday that the agency has concerns about drugs made by compounding pharmacies and still sees problems with them six years after a fungal meningitis outbreak tied to a Massachusetts pharmacy killed 76 people.Reuters Health Information (Source: Medscape Allergy Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Kvko9j
A top U.S. Food and Drug Administration official testified on Monday that the agency has concerns about drugs made by compounding pharmacies and still sees problems with them six years after a fungal meningitis outbreak tied to a Massachusetts pharmacy killed 76 people.Reuters Health Information (Source: Medscape Allergy Headlines)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Kvko9j
The publisher regrets that the abstract was missing in the original publication of this article.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QaEPxn
The publisher regrets that the abstract was missing in the original publication of this article.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QaEPxn
A 61-year-old woman who lost her nose, upper lip, and most of her midface bony structures due to cancer 20 years ago underwent advanced surgical reconstruction. This patient had previously undergone multiple reconstructive surgeries that failed to satisfactorily restore her nose. Therefore, a multi-stage reconstruction was performed to recreate a complete nose and increase her upper lip length. Due to a lack of sufficient facial bone and nasal supporting structures, the reconstruction was extremely challenging.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R0QewN
This is the first double-blind, placebo-controlled study showing that vaccination with recombinant hypoallergenic allergen-derivatives is safe and induces sustained allergen-specific IgG responses which block allergic patients IgE binding to the allergen.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DRBbCY
Environmental events in early in life are critical to development of allergic diseases later in life. We found IgE-class-specific immunosuppression in offspring whose mothers had been administered anti-IgE during pregnancy.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S5gg1Y
We found upregulation of 47 immunoglobulin genes and 22 S. aureus infection-related genes in refractory atopic keratoconjunctivitis tissue by RNA-seq analysis, suggesting that lymphoid neogenesis and stimuli from infection are essential components of the disorder.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DPdz1z
A 61-year-old woman who lost her nose, upper lip, and most of her midface bony structures due to cancer 20 years ago underwent advanced surgical reconstruction. This patient had previously undergone multiple reconstructive surgeries that failed to satisfactorily restore her nose. Therefore, a multi-stage reconstruction was performed to recreate a complete nose and increase her upper lip length. Due to a lack of sufficient facial bone and nasal supporting structures, the reconstruction was extremely challenging.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2R0QewN
Environmental events in early in life are critical to development of allergic diseases later in life. We found IgE-class-specific immunosuppression in offspring whose mothers had been administered anti-IgE during pregnancy.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2S5gg1Y
We found upregulation of 47 immunoglobulin genes and 22 S. aureus infection-related genes in refractory atopic keratoconjunctivitis tissue by RNA-seq analysis, suggesting that lymphoid neogenesis and stimuli from infection are essential components of the disorder.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2DPdz1z
Background: Lower lip reconstruction remains a challenging task due to multi-functional and high aesthetic requirements that have to be achieved for successful outcome. This is particularly true to near-total lower lip defects, encompassing over 70% of lower lip loss due to cancer, trauma or burns. Despite the fact that numerous flaps and their modifications have been described over the past century, only a few valuable techniques and concepts withstood the test of time for sub-total lower lip defects, each having their own drawbacks.
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This study was designed to introduce a novel method of applying osteosynthetic materials to the upper zygomatic arch border for fracture fixation through a temporal incision, and analyze the radiologic morphometric dimensions of the arch to verify its validity.
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Breast reconstruction after mastectomy offers significant improvements in quality of life for breast cancer (BC) patients. To improve access to post-mastectomy breast reconstruction (PMBR) for BC patients in the U.S., the Women's Health and Cancer Rights Act (WHCRA) was implemented in 1999, mandating coverage of PMBR by all insurers. Prior to WHCRA, post mastectomy breast reconstruction (PMBR) was variably covered by insurers as it was primarily viewed as a cosmetic procedure. The objectives of this study were to explore whether the incidence of PMBR has changed over time and whether patient age, receipt of radiation therapy, or tumor grade has an effect on the incidence of reconstruction over time.
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To investigate expression of components of the renin-angiotensin system (RAS): pro-renin receptor (PRR), angiotensin converting enzyme (ACE), angiotensin II receptor 1 (ATIIR1) and angiotensin II receptor 2 (ATIIR2) by the cancer stem cell (CSC) subpopulations in moderately differentiated head and neck cutaneous squamous cell carcinoma (MDHNCSCC).
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Breast augmentation is one of the most common aesthetic procedures performed worldwide. One of the worst associated complications is implant rupture, a topic that will be addressed in the present study. The risk of developing silicone gel breast implant rupture following breast augmentation is associated with multiple factors, including: older generation implant, increased implant age, implant type, specific manufacturer, severe capsular contracture (Baker grade III or IV), and the presence of local symptoms.
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Various functional outcomes after upper blepharoplasty are reported in the literature. We systematically reviewed the literature to assess the objective and subjective functional effects of upper blepharoplasty.
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CT angiography (CTA) can be performed pre-operatively for perforator mapping in autologous breast reconstruction. The full impact of incidental CTA findings on breast reconstruction remains unclear.
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Surgical site infection has considerable cost implications for healthcare providers. Evidence suggests that the use of Micropore™ tape as a dressing for surgical incisions may be associated with reduced/comparable rates of infection in surgical wounds. 3M™ Micropore™ tape is significantly cheaper than conventional wound dressings. The purpose of this study was to compare differences in the rate of wound healing problems including superficial incisional surgical site infection (SSI) and wound healing problems following cosmetic breast procedures between Micropore™ tape and other common wound dressings.
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Background: Lower lip reconstruction remains a challenging task due to multi-functional and high aesthetic requirements that have to be achieved for successful outcome. This is particularly true to near-total lower lip defects, encompassing over 70% of lower lip loss due to cancer, trauma or burns. Despite the fact that numerous flaps and their modifications have been described over the past century, only a few valuable techniques and concepts withstood the test of time for sub-total lower lip defects, each having their own drawbacks.
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This study was designed to introduce a novel method of applying osteosynthetic materials to the upper zygomatic arch border for fracture fixation through a temporal incision, and analyze the radiologic morphometric dimensions of the arch to verify its validity.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Kpwy3s
Breast reconstruction after mastectomy offers significant improvements in quality of life for breast cancer (BC) patients. To improve access to post-mastectomy breast reconstruction (PMBR) for BC patients in the U.S., the Women's Health and Cancer Rights Act (WHCRA) was implemented in 1999, mandating coverage of PMBR by all insurers. Prior to WHCRA, post mastectomy breast reconstruction (PMBR) was variably covered by insurers as it was primarily viewed as a cosmetic procedure. The objectives of this study were to explore whether the incidence of PMBR has changed over time and whether patient age, receipt of radiation therapy, or tumor grade has an effect on the incidence of reconstruction over time.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BoYPUF
To investigate expression of components of the renin-angiotensin system (RAS): pro-renin receptor (PRR), angiotensin converting enzyme (ACE), angiotensin II receptor 1 (ATIIR1) and angiotensin II receptor 2 (ATIIR2) by the cancer stem cell (CSC) subpopulations in moderately differentiated head and neck cutaneous squamous cell carcinoma (MDHNCSCC).
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2KoNZkA
Breast augmentation is one of the most common aesthetic procedures performed worldwide. One of the worst associated complications is implant rupture, a topic that will be addressed in the present study. The risk of developing silicone gel breast implant rupture following breast augmentation is associated with multiple factors, including: older generation implant, increased implant age, implant type, specific manufacturer, severe capsular contracture (Baker grade III or IV), and the presence of local symptoms.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BqMbVl
Various functional outcomes after upper blepharoplasty are reported in the literature. We systematically reviewed the literature to assess the objective and subjective functional effects of upper blepharoplasty.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Kt9jWc
CT angiography (CTA) can be performed pre-operatively for perforator mapping in autologous breast reconstruction. The full impact of incidental CTA findings on breast reconstruction remains unclear.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2BoX0az
Surgical site infection has considerable cost implications for healthcare providers. Evidence suggests that the use of Micropore™ tape as a dressing for surgical incisions may be associated with reduced/comparable rates of infection in surgical wounds. 3M™ Micropore™ tape is significantly cheaper than conventional wound dressings. The purpose of this study was to compare differences in the rate of wound healing problems including superficial incisional surgical site infection (SSI) and wound healing problems following cosmetic breast procedures between Micropore™ tape and other common wound dressings.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2Kp3Gbr
The aim of this prospective cohort study was to evaluate how the radiation technique can affect crestal bone loss and the implant survival rate in head and neck cancer patients treated with radiotherapy. In this study, the type of radiotherapy treatment, i.e. three-dimensional conformal radiotherapy (3D-CRT) or intensity modulated radiation therapy (IMRT), was the predictor variable. The primary outcome variable was crestal bone loss, recorded at implant placement and after 3, 6, 12, and 24 months.
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The aim of this prospective cohort study was to evaluate how the radiation technique can affect crestal bone loss and the implant survival rate in head and neck cancer patients treated with radiotherapy. In this study, the type of radiotherapy treatment, i.e. three-dimensional conformal radiotherapy (3D-CRT) or intensity modulated radiation therapy (IMRT), was the predictor variable. The primary outcome variable was crestal bone loss, recorded at implant placement and after 3, 6, 12, and 24 months.
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This study investigated the impact of leukoaraiosis (LA) involving the contralateral corticobulbar tract (CBT) on dysphagia in patients with unilateral corona radiata (CR) infarction with CBT involvement. Patients admitted to the Department of Neurology (September 2011–August 2014) were evaluated; those with a first episode of acute unilateral CR infarction involving the CBT and with LA were included. The 'Case' group comprised patients with LA involving the contralateral CBT; the 'Control' group comprised patients with LA not involving the contralateral CBT. The primary outcome was the feeding method at discharge; secondary outcomes were the feeding method at admission and results of the bedside swallowing test, videofluoroscopic swallowing study (VFSS), videofluoroscopic dysphagia scale, penetration–aspiration scale, American Speech–Language–Hearing Association National Outcome Measurement System Swallowing Scale (ASHA NOMS), oral transit time, and pharyngeal transit time. Infarct size was measured using brain magnetic resonance imaging; LA severity was rated using the Fazekas scale. Eighty-one patients were included (mean age 64.6 ± 11.5 years; 64% male; Case group: 20, 5 underwent VFSS; Control group: 67, 11 underwent VFSS). The Case group was older and had higher total Fazekas scale score than the Control group. The feeding method at discharge and ASHA NOMS score were significantly worse in the Case group than in the Control group. Multivariate analysis revealed that LA involving the contralateral CBT independently predicted the feeding method at discharge and ASHA NOMS score. In conclusion, LA involving the contralateral CBT is associated with dysphagia in patients with unilateral CR infarction involving the CBT.
This study investigated the impact of leukoaraiosis (LA) involving the contralateral corticobulbar tract (CBT) on dysphagia in patients with unilateral corona radiata (CR) infarction with CBT involvement. Patients admitted to the Department of Neurology (September 2011–August 2014) were evaluated; those with a first episode of acute unilateral CR infarction involving the CBT and with LA were included. The 'Case' group comprised patients with LA involving the contralateral CBT; the 'Control' group comprised patients with LA not involving the contralateral CBT. The primary outcome was the feeding method at discharge; secondary outcomes were the feeding method at admission and results of the bedside swallowing test, videofluoroscopic swallowing study (VFSS), videofluoroscopic dysphagia scale, penetration–aspiration scale, American Speech–Language–Hearing Association National Outcome Measurement System Swallowing Scale (ASHA NOMS), oral transit time, and pharyngeal transit time. Infarct size was measured using brain magnetic resonance imaging; LA severity was rated using the Fazekas scale. Eighty-one patients were included (mean age 64.6 ± 11.5 years; 64% male; Case group: 20, 5 underwent VFSS; Control group: 67, 11 underwent VFSS). The Case group was older and had higher total Fazekas scale score than the Control group. The feeding method at discharge and ASHA NOMS score were significantly worse in the Case group than in the Control group. Multivariate analysis revealed that LA involving the contralateral CBT independently predicted the feeding method at discharge and ASHA NOMS score. In conclusion, LA involving the contralateral CBT is associated with dysphagia in patients with unilateral CR infarction involving the CBT.
The reliability of assessment of the artery of Adamkiewicz before the aortic repair is highly dependent on the display of the continuity of this artery with the aorta, mainly around the vertebral pedicle, by computed tomography angiography (CTA). We hypothesized that the sharp filter kernel can improve visualization of this continuity of the vessel structure because of its edge enhancement and high-spatial resolution. This study was performed to compare the subjective and objective image quality of spinal CTA reconstructed with sharp and smooth filter kernels.
We retrospectively reviewed 40 consecutive patients who had undergone 80-kV CTA to detect the artery of Adamkiewicz before aortic repair. We measured the CT number and the contrast-to-noise ratio of the anterior spinal artery to the spinal cord. Furthermore, the continuity of the artery of Adamkiewicz was evaluated using a 3-point scale (2 points, absolute; 0 points, undetectable).
CTA with the sharp filter kernel showed a significantly higher CT number and contrast-to-noise ratio of the spinal artery than did CTA with the smooth filter kernel (P < .001 for both). Moreover, the sharp filter kernel showed a significantly higher continuity of the artery of Adamkiewicz with the aorta than did the smooth filter kernel (P < .001).
The sharp filter kernel significantly improved the image quality in low-tube-voltage CTA for the assessment of the artery of Adamkiewicz. Thus, CTA with the sharp filter kernel can generate a high-confidence level in the evaluation of the artery of Adamkiewicz.
The reliability of assessment of the artery of Adamkiewicz before the aortic repair is highly dependent on the display of the continuity of this artery with the aorta, mainly around the vertebral pedicle, by computed tomography angiography (CTA). We hypothesized that the sharp filter kernel can improve visualization of this continuity of the vessel structure because of its edge enhancement and high-spatial resolution. This study was performed to compare the subjective and objective image quality of spinal CTA reconstructed with sharp and smooth filter kernels.
We retrospectively reviewed 40 consecutive patients who had undergone 80-kV CTA to detect the artery of Adamkiewicz before aortic repair. We measured the CT number and the contrast-to-noise ratio of the anterior spinal artery to the spinal cord. Furthermore, the continuity of the artery of Adamkiewicz was evaluated using a 3-point scale (2 points, absolute; 0 points, undetectable).
CTA with the sharp filter kernel showed a significantly higher CT number and contrast-to-noise ratio of the spinal artery than did CTA with the smooth filter kernel (P < .001 for both). Moreover, the sharp filter kernel showed a significantly higher continuity of the artery of Adamkiewicz with the aorta than did the smooth filter kernel (P < .001).
The sharp filter kernel significantly improved the image quality in low-tube-voltage CTA for the assessment of the artery of Adamkiewicz. Thus, CTA with the sharp filter kernel can generate a high-confidence level in the evaluation of the artery of Adamkiewicz.
The lip profile plays an important role in the perception of facial aesthetics; lip morphology and aesthetics research is receiving increasing attention. The advancement of research tools such as three-dimensional imaging technology has led to the clarification of lip morphologic and aesthetic characteristics. After studies of lip characteristics according to gender, ethnicity and age provided basic data, studies on lip aesthetics have been conducted by scholars worldwide. These studies could provide a basic theory to support diagnosis and treatment options, as well as the basis for evaluative criteria for precise treatment and technical improvements. According to the conclusions of the above studies, new ideas for cosmetic surgery design, including lip, perioral and labial–facial relationships, have been discovered.
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
The lip profile plays an important role in the perception of facial aesthetics; lip morphology and aesthetics research is receiving increasing attention. The advancement of research tools such as three-dimensional imaging technology has led to the clarification of lip morphologic and aesthetic characteristics. After studies of lip characteristics according to gender, ethnicity and age provided basic data, studies on lip aesthetics have been conducted by scholars worldwide. These studies could provide a basic theory to support diagnosis and treatment options, as well as the basis for evaluative criteria for precise treatment and technical improvements. According to the conclusions of the above studies, new ideas for cosmetic surgery design, including lip, perioral and labial–facial relationships, have been discovered.
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
The lip profile plays an important role in the perception of facial aesthetics; lip morphology and aesthetics research is receiving increasing attention. The advancement of research tools such as three-dimensional imaging technology has led to the clarification of lip morphologic and aesthetic characteristics. After studies of lip characteristics according to gender, ethnicity and age provided basic data, studies on lip aesthetics have been conducted by scholars worldwide. These studies could provide a basic theory to support diagnosis and treatment options, as well as the basis for evaluative criteria for precise treatment and technical improvements. According to the conclusions of the above studies, new ideas for cosmetic surgery design, including lip, perioral and labial–facial relationships, have been discovered.
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
The lip profile plays an important role in the perception of facial aesthetics; lip morphology and aesthetics research is receiving increasing attention. The advancement of research tools such as three-dimensional imaging technology has led to the clarification of lip morphologic and aesthetic characteristics. After studies of lip characteristics according to gender, ethnicity and age provided basic data, studies on lip aesthetics have been conducted by scholars worldwide. These studies could provide a basic theory to support diagnosis and treatment options, as well as the basis for evaluative criteria for precise treatment and technical improvements. According to the conclusions of the above studies, new ideas for cosmetic surgery design, including lip, perioral and labial–facial relationships, have been discovered.
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
OBJECTIVES: Sodium bromate is a strong oxidant, and bromate intoxication can cause irreversible severe-to-profound sensorineural hearing loss. This paper reports the first case in the English literature of bromate-induced hearing loss with hearing recovery... (Source: SafetyLit)
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OBJECTIVES: Sodium bromate is a strong oxidant, and bromate intoxication can cause irreversible severe-to-profound sensorineural hearing loss. This paper reports the first case in the English literature of bromate-induced hearing loss with hearing recovery... (Source: SafetyLit)
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Publication date: Available online 20 November 2018Source: Redox BiologyAuthor(s): Ye-Ri Kim, Jeong-In Baek, Sung Hwan Kim, Min-A. Kim, Byeonghyeon Lee, Nari Ryu, Kyung-Hee Kim, Deok-Gyun Choi, Hye-Min Kim, Michael P. Murphy, Greg Macpherson, Yeon-Sik Choo, Jinwoong Bok, Kyu-Yup Lee, Jeen-Woo Park, Un-Kyung KimAbstractMitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) is a major NADPH-producing enzyme which is essential for maintaining the mitochondrial redox balance in cells. We sought to determine whether IDH2 deficiency induces mitochondrial dysfunction and modulates auditory function, and investigated the protective potential of an antioxidant agent against reactive oxygen species (ROS)-induced cochlear damage in Idh2 knockout (Idh2−/−) mice. Idh2 deficiency leads to d...
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Publication date: Available online 19 November 2018Source: Mammalian BiologyAuthor(s): Lucie Pleštilová, Ema Hrouzková, Hynek Burda, Limin Hua, Radim ŠumberaAbstractAcoustic conditions in burrows are different from those aboveground and restrict hearing of subterranean mammals to low frequencies, which is reflected in the ear morphology. While low-frequency adaptations of the middle ear attracted more attention of researches, the inner ear remained rather understudied. Here, we examined the cochlea of the inner ear of the Gansu zokor (Eospalax cansus), a subterranean rodent from the Tibetan Plateau. We focused on the quantitative parameters of the organ of Corti, which are assumed to determine hearing sensitivity and frequency tuning. Apart from the morphological traits common to the e...
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AbstractMore than 80% of people with hearing loss (HL) live in low- and middle-income countries. Up to 90% of deaf children are born to hearing parents, leading to novel parenting, communication, educational, and psychosocial experiences. Half of congenital pre-lingual HL is genetic, with a relatively high recurrence risk that may lead to specific challenges for parents of affected children. Currently, little is known of genes implicated and causative mutations for most populations who have HL in Sub-Saharan Africa, as well as genetic counseling services needs for this population. Therefore, this study aimed to explore parents ' perceptions and understanding of the genetic etiology of their child's HL, in order to inform policies and services. In-depth qualitative interviews were condu...
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Publication date: Available online 20 November 2018Source: LinguaAuthor(s): Hanna Jaeger, Sarah HarzerAbstractBased on qualitative analysis of signed data generated in the context of ten focus groups conducted with 31 deaf signers throughout Germany, the paper explores how deaf users of German Sign Language (Deutsche Gebärdensprache, DGS) position themselves in conversational settings. It will be shown that creatively manipulating the visual-spatial articulatory resources of DGS, the protagonists subtly but clearly delineate themselves from others, socially positioning themselves not only as rather skillful, but even more crucially, as authentic signers. Examining the enregisterment of creative language use (CLU) as indexical of authentic signing within the DGS community, the paper paves ...
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AbstractMore than 80% of people with hearing loss (HL) live in low- and middle-income countries. Up to 90% of deaf children are born to hearing parents, leading to novel parenting, communication, educational, and psychosocial experiences. Half of congenital pre-lingual HL is genetic, with a relatively high recurrence risk that may lead to specific challenges for parents of affected children. Currently, little is known of genes implicated and causative mutations for most populations who have HL in Sub-Saharan Africa, as well as genetic counseling services needs for this population. Therefore, this study aimed to explore parents ' perceptions and understanding of the genetic etiology of their child's HL, in order to inform policies and services. In-depth qualitative interviews were condu...
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Publication date: Available online 20 November 2018Source: LinguaAuthor(s): Hanna Jaeger, Sarah HarzerAbstractBased on qualitative analysis of signed data generated in the context of ten focus groups conducted with 31 deaf signers throughout Germany, the paper explores how deaf users of German Sign Language (Deutsche Gebärdensprache, DGS) position themselves in conversational settings. It will be shown that creatively manipulating the visual-spatial articulatory resources of DGS, the protagonists subtly but clearly delineate themselves from others, socially positioning themselves not only as rather skillful, but even more crucially, as authentic signers. Examining the enregisterment of creative language use (CLU) as indexical of authentic signing within the DGS community, the paper paves ...
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This study uses the L2 Motivational Self System framework to explore the motivational profiles of 114 non-Arab expatriate teenagers attending UK curriculum schools in the United Arab Emirates. The study specifically investigates their motivational self concepts as these relate to the simultaneous learning of English, Arabic and, in some instances, an additional foreign language. The results of the study indicate that while participants are most motivated to learn English, this does not have a negative effect on their motivation to learn languages other than English (LOTEs). The findings also suggest that competitiveness positively correlates with an individual's motivation to be multilingual. As for Arabic, the study shows that participants approach its study in mostly functional terms, an...
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Publication date: Available online 19 November 2018Source: LinguaAuthor(s): Jeff MacSwan (Source: Lingua)
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Publication date: Available online 19 November 2018Source: Speech CommunicationAuthor(s): Weitao Yuan, Boxin He, Shengbei Wang, Jianming Wang, Masashi UnokiAbstractDeep Recurrent Neural Network (DRNN) based monaural singing voice separation (MSVS) methods have recently obtained impressive separation results. Most of DRNN based methods directly take the magnitude spectra of the mixture signal as the input feature, which has high dimensionality and contains redundant information. The DRNN based models, however, cannot extract the effective low-dimensional and de-redundant representations from the magnitude spectra. In this paper, we propose an Enhanced Feature Network (EFN) to extract effective representations of the magnitude spectra, i.e., enhanced-feature, for MSVS. The generation of enha...
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Publication date: Available online 20 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Xiaoyue Xu, Xiaoyu Tang, Xiaoxu Wu, Xiufang FengAbstractSorafenib (SRF) is a well-known tyrosine kinase inhibiting anticancer drug which iseffectual against multiple carcinomas especially gastric cancers by targeting the Ras/Raf/Mek/Erk cascade pathway and blocking the tumor cell proliferation. In the present work, we have reduced graphene oxide (GO) in presence of sorafenib using ascorbic as green reducing agent for the treatment of gastric cancers. Sorafenib reduced graphene oxide (SRGO) were obtained with a transparent and smoothmorphology. The drug loaded SRGO has presented significant cytotoxic effect against SGC7901 cancer cells when compared to that of the free ...
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Publication date: Available online 20 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): László Kőrösi, Sakina Bouderias, Kristóf Csepregi, Balázs Bognár, Péter Teszlák, Alice Scarpellini, Andrea Castelli, Éva Hideg, Gábor JakabAbstractOver the past decades, nanotechnology has received great attention and brought revolutionary solutions for a number of challenges in scientific fields. Industrial, agricultural and medical applications of engineered nanomaterials have increased intensively. The ability of titanium dioxide nanoparticles (TiO2 NPs) to produce reactive oxygen species (ROS), when excited by ultra-violet (UV) light, makes them useful for effectively inactivate various pathogens. It is known that ROS also have signalling role in living ...
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In this study, unique properties of colored lights have been observed on induction of somatic embryos from non-embryonic calli cultures of A. bracteosa. The maximum callogenic response (92.32%) from leaf explants was observed on Murashige and Skoog (MS) medium augmented with benzyl adenine (BA; 2.0 l−1) and 2, 4-Dichlorophenoxy acetic acid (2.4-D; 1.0 mg l−1). Calli cultures with same hormonal concentrations were placed under different spectral lights for somatic embryogenesis and photochemical variations. Red lights were found effective for maximum somatic embryos induction (92.75%) with optimum biomass accumulation (152.64 g l−1) on day 40. Similarly, among all the spectral lights, red light exhibited the highest DPPH-radical scavenging activity (DRSA; 92.86%). In contras...
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Publication date: Available online 20 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Chunyang Fang, Ziping Ma, Liqiu Chen, Hongjie Li, Chao Jiang, Wenbin ZhangAbstractIn the present work, a facile biosynthetic approach for the synthesis of AuNPs using bark extract of Juglans regia (J. regia) is reported. Ultra-violet visible (UV–vis) absorption spectroscopic studies exhibited and narrow SPR absorption band at 540 nm, represented the isotropy in particle size. The transmission electron microscopy (TEM) and X-ray diffraction (XRD) analysis, confirmed the fabrication of spherical and crystalline nanoparticles of average size of about 14 nm. Also, typical characteristic selected area electron diffraction (SAED) pattern showed the crystalline nature o...
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Publication date: Available online 20 November 2018Source: Language & CommunicationAuthor(s): Marco JacquemetAbstractThe experience of linguistic globalization, and the sociolinguistic disorder it entails, requires a serious retooling of most basic units of sociolinguistic analysis—foremost among them the speech community. The randomness and indeterminacy of contemporary flows of people, knowledge, texts, and commodities across social and geographical space is affecting the linguistic ideological boundaries of inclusion and exclusion. In particular, we can no longer assume that shared knowledge, especially indexical knowledge, can still provide a common ground to bind people together, negotiate conflicts, and share/transmit ideologies. Using data from a digital ethnography of a multiling...
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ConclusionFrom the perspective of the person who stutters, self-disclosure at the outset of the communicative interaction did not have a decisive impact on the cognitive-affective or speech variables. (Source: Journal of Fluency Disorders)
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Publication date: February 2019Source: Journal of Memory and Language, Volume 104Author(s): (Source: Journal of Memory and Language)
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CONCLUSIONS: According to this literature review, successful inter-professional patient-orientated care is promoted by being informed about the various functions of team members from different disciplines, about the role each member plays within the team and communication styles. Means of improving communication are being outlined. Implications for Rehabilitation Inter-professional communication is promoted by cross-professional team organization. Inter-professional communication should be included in vocational and on-the-job-training and supervision. Barriers for communication in teams are different terminologies and differences in role perception. PMID: 30457016 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
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Applying state-of-the-art machine learning techniques to medical images requires a thorough selection and normalization of input data. One of such steps in digital mammography screening for breast cancer is the labeling and removal of special diagnostic views, in which diagnostic tools or magnification are applied to assist in assessment of suspicious initial findings. As a common task in medical informatics is prediction of disease and its stage, these special diagnostic views, which are only enriched among the cohort of diseased cases, will bias machine learning disease predictions. In order to automate this process, here, we develop a machine learning pipeline that utilizes both DICOM headers and images to predict such views in an automatic manner, allowing for their removal and the generation of unbiased datasets. We achieve AUC of 99.72% in predicting special mammogram views when combining both types of models. Finally, we apply these models to clean up a dataset of about 772,000 images with expected sensitivity of 99.0%. The pipeline presented in this paper can be applied to other datasets to obtain high-quality image sets suitable to train algorithms for disease detection.
Airway diseases are frequently related to morphological changes that may influence lung physiology. Accurate airway region segmentation may be useful for quantitative evaluation of disease prognosis and therapy efficacy. The information can also be applied to understand the fundamental mechanisms of various lung diseases. We present a hybrid method to automatically segment the airway regions on 3D volume chest computed tomography (CT) scans. This method uses multi-scale filtering and support vector machine (SVM) classification. The proposed scheme is comprised of two hybrid steps. First, a tubular structure-based multi-scale filter is applied to find the initial candidate airway regions. Second, for identifying candidate airway regions using the fuzzy connectedness technique, the small and disconnected branches of airway regions are detected using SVM classification trained to differentiate between airway and non-airway regions through texture analysis of user-defined landmark points. For development and evaluation of the method, two datasets were incorporated: (1) 55 lung-CT volumes from the Korean Obstructive Lung Disease (KOLD) Cohort Study and (2) 20 cases from the publicly open database (EXACT′09). The average tree-length detection rates of EXACT′09 and KOLD were 56.9 ± 11.0 and 70.5 ± 8.98, respectively. Comparison of the results for the EXACT′09 data set between the presented method and other methods revealed that our approach was a high performer. The method limitations were higher false-positive rates than those of the other methods and risk of leakage. In future studies, application of a convolutional neural network will help overcome these shortcomings.
Publication date: Available online 20 November 2018Source: LinguaAuthor(s): Hanna Jaeger, Sarah HarzerAbstractBased on qualitative analysis of signed data generated in the context of ten focus groups conducted with 31 deaf signers throughout Germany, the paper explores how deaf users of German Sign Language (Deutsche Gebärdensprache, DGS) position themselves in conversational settings. It will be shown that creatively manipulating the visual-spatial articulatory resources of DGS, the protagonists subtly but clearly delineate themselves from others, socially positioning themselves not only as rather skillful, but even more crucially, as authentic signers. Examining the enregisterment of creative language use (CLU) as indexical of authentic signing within the DGS community, the paper paves ...
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This study uses the L2 Motivational Self System framework to explore the motivational profiles of 114 non-Arab expatriate teenagers attending UK curriculum schools in the United Arab Emirates. The study specifically investigates their motivational self concepts as these relate to the simultaneous learning of English, Arabic and, in some instances, an additional foreign language. The results of the study indicate that while participants are most motivated to learn English, this does not have a negative effect on their motivation to learn languages other than English (LOTEs). The findings also suggest that competitiveness positively correlates with an individual's motivation to be multilingual. As for Arabic, the study shows that participants approach its study in mostly functional terms, an...
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Publication date: Available online 19 November 2018Source: LinguaAuthor(s): Jeff MacSwan (Source: Lingua)
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Publication date: Available online 19 November 2018Source: Speech CommunicationAuthor(s): Weitao Yuan, Boxin He, Shengbei Wang, Jianming Wang, Masashi UnokiAbstractDeep Recurrent Neural Network (DRNN) based monaural singing voice separation (MSVS) methods have recently obtained impressive separation results. Most of DRNN based methods directly take the magnitude spectra of the mixture signal as the input feature, which has high dimensionality and contains redundant information. The DRNN based models, however, cannot extract the effective low-dimensional and de-redundant representations from the magnitude spectra. In this paper, we propose an Enhanced Feature Network (EFN) to extract effective representations of the magnitude spectra, i.e., enhanced-feature, for MSVS. The generation of enha...
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Publication date: Available online 20 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Xiaoyue Xu, Xiaoyu Tang, Xiaoxu Wu, Xiufang FengAbstractSorafenib (SRF) is a well-known tyrosine kinase inhibiting anticancer drug which iseffectual against multiple carcinomas especially gastric cancers by targeting the Ras/Raf/Mek/Erk cascade pathway and blocking the tumor cell proliferation. In the present work, we have reduced graphene oxide (GO) in presence of sorafenib using ascorbic as green reducing agent for the treatment of gastric cancers. Sorafenib reduced graphene oxide (SRGO) were obtained with a transparent and smoothmorphology. The drug loaded SRGO has presented significant cytotoxic effect against SGC7901 cancer cells when compared to that of the free ...
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Publication date: Available online 20 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): László Kőrösi, Sakina Bouderias, Kristóf Csepregi, Balázs Bognár, Péter Teszlák, Alice Scarpellini, Andrea Castelli, Éva Hideg, Gábor JakabAbstractOver the past decades, nanotechnology has received great attention and brought revolutionary solutions for a number of challenges in scientific fields. Industrial, agricultural and medical applications of engineered nanomaterials have increased intensively. The ability of titanium dioxide nanoparticles (TiO2 NPs) to produce reactive oxygen species (ROS), when excited by ultra-violet (UV) light, makes them useful for effectively inactivate various pathogens. It is known that ROS also have signalling role in living ...
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In this study, unique properties of colored lights have been observed on induction of somatic embryos from non-embryonic calli cultures of A. bracteosa. The maximum callogenic response (92.32%) from leaf explants was observed on Murashige and Skoog (MS) medium augmented with benzyl adenine (BA; 2.0 l−1) and 2, 4-Dichlorophenoxy acetic acid (2.4-D; 1.0 mg l−1). Calli cultures with same hormonal concentrations were placed under different spectral lights for somatic embryogenesis and photochemical variations. Red lights were found effective for maximum somatic embryos induction (92.75%) with optimum biomass accumulation (152.64 g l−1) on day 40. Similarly, among all the spectral lights, red light exhibited the highest DPPH-radical scavenging activity (DRSA; 92.86%). In contras...
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Publication date: Available online 20 November 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Chunyang Fang, Ziping Ma, Liqiu Chen, Hongjie Li, Chao Jiang, Wenbin ZhangAbstractIn the present work, a facile biosynthetic approach for the synthesis of AuNPs using bark extract of Juglans regia (J. regia) is reported. Ultra-violet visible (UV–vis) absorption spectroscopic studies exhibited and narrow SPR absorption band at 540 nm, represented the isotropy in particle size. The transmission electron microscopy (TEM) and X-ray diffraction (XRD) analysis, confirmed the fabrication of spherical and crystalline nanoparticles of average size of about 14 nm. Also, typical characteristic selected area electron diffraction (SAED) pattern showed the crystalline nature o...
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Publication date: Available online 20 November 2018Source: Language & CommunicationAuthor(s): Marco JacquemetAbstractThe experience of linguistic globalization, and the sociolinguistic disorder it entails, requires a serious retooling of most basic units of sociolinguistic analysis—foremost among them the speech community. The randomness and indeterminacy of contemporary flows of people, knowledge, texts, and commodities across social and geographical space is affecting the linguistic ideological boundaries of inclusion and exclusion. In particular, we can no longer assume that shared knowledge, especially indexical knowledge, can still provide a common ground to bind people together, negotiate conflicts, and share/transmit ideologies. Using data from a digital ethnography of a multiling...
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ConclusionFrom the perspective of the person who stutters, self-disclosure at the outset of the communicative interaction did not have a decisive impact on the cognitive-affective or speech variables. (Source: Journal of Fluency Disorders)
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Publication date: February 2019Source: Journal of Memory and Language, Volume 104Author(s): (Source: Journal of Memory and Language)
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CONCLUSIONS: According to this literature review, successful inter-professional patient-orientated care is promoted by being informed about the various functions of team members from different disciplines, about the role each member plays within the team and communication styles. Means of improving communication are being outlined. Implications for Rehabilitation Inter-professional communication is promoted by cross-professional team organization. Inter-professional communication should be included in vocational and on-the-job-training and supervision. Barriers for communication in teams are different terminologies and differences in role perception. PMID: 30457016 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
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Applying state-of-the-art machine learning techniques to medical images requires a thorough selection and normalization of input data. One of such steps in digital mammography screening for breast cancer is the labeling and removal of special diagnostic views, in which diagnostic tools or magnification are applied to assist in assessment of suspicious initial findings. As a common task in medical informatics is prediction of disease and its stage, these special diagnostic views, which are only enriched among the cohort of diseased cases, will bias machine learning disease predictions. In order to automate this process, here, we develop a machine learning pipeline that utilizes both DICOM headers and images to predict such views in an automatic manner, allowing for their removal and the generation of unbiased datasets. We achieve AUC of 99.72% in predicting special mammogram views when combining both types of models. Finally, we apply these models to clean up a dataset of about 772,000 images with expected sensitivity of 99.0%. The pipeline presented in this paper can be applied to other datasets to obtain high-quality image sets suitable to train algorithms for disease detection.
Airway diseases are frequently related to morphological changes that may influence lung physiology. Accurate airway region segmentation may be useful for quantitative evaluation of disease prognosis and therapy efficacy. The information can also be applied to understand the fundamental mechanisms of various lung diseases. We present a hybrid method to automatically segment the airway regions on 3D volume chest computed tomography (CT) scans. This method uses multi-scale filtering and support vector machine (SVM) classification. The proposed scheme is comprised of two hybrid steps. First, a tubular structure-based multi-scale filter is applied to find the initial candidate airway regions. Second, for identifying candidate airway regions using the fuzzy connectedness technique, the small and disconnected branches of airway regions are detected using SVM classification trained to differentiate between airway and non-airway regions through texture analysis of user-defined landmark points. For development and evaluation of the method, two datasets were incorporated: (1) 55 lung-CT volumes from the Korean Obstructive Lung Disease (KOLD) Cohort Study and (2) 20 cases from the publicly open database (EXACT′09). The average tree-length detection rates of EXACT′09 and KOLD were 56.9 ± 11.0 and 70.5 ± 8.98, respectively. Comparison of the results for the EXACT′09 data set between the presented method and other methods revealed that our approach was a high performer. The method limitations were higher false-positive rates than those of the other methods and risk of leakage. In future studies, application of a convolutional neural network will help overcome these shortcomings.
