Δευτέρα 17 Σεπτεμβρίου 2018
Head And Neck Cancer Treatment Market Promising regions, Driver, Key Players, Technology, Trends and Forecast to ...
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Head And Neck Cancer Treatment Market Promising regions, Driver, Key Players, Technology, Trends and Forecast to ...
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The Canadian Dementia Imaging Protocol: Harmonizing National Cohorts
Journal of Magnetic Resonance Imaging, EarlyView.
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The Canadian Dementia Imaging Protocol: Harmonizing National Cohorts
Journal of Magnetic Resonance Imaging, EarlyView.
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FIERCE for a cure: Natick boot camp raises money for cancer research
| FIERCE for a cure: Natick boot camp raises money for cancer research Wicked Local RockportFull coverage |
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FIERCE for a cure: Natick boot camp raises money for cancer research
| FIERCE for a cure: Natick boot camp raises money for cancer research Wicked Local RockportFull coverage |
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Fall for apples
| Fall for apples Brainerd DispatchFull coverage |
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TMJ pathomorphology in patients with JIA-radiographic parameters for early diagnosis-
Juvenile idiopathic arthritis (JIA) is often accompanied by pathomorphological changes to the temporomandibular joint (TMJ). By analyzing orthodontical orthopantomograms of JIA patients the aims of the study w...
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Fall for apples
| Fall for apples Brainerd DispatchFull coverage |
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TMJ pathomorphology in patients with JIA-radiographic parameters for early diagnosis-
Juvenile idiopathic arthritis (JIA) is often accompanied by pathomorphological changes to the temporomandibular joint (TMJ). By analyzing orthodontical orthopantomograms of JIA patients the aims of the study w...
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The factors that influence oral health-related quality of life in young adults
Young adulthood is a time when subjects transform their role from a dependent child to an independent social identity. This cross-sectional study aimed to analyze the sociodemographic and clinical factors that...
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Validation of the Korean version of the avoidance endurance behavior questionnaire in patients with chronic pain
The avoidance-endurance model suggests both fear-avoidance responses and endurance-related responses could affect the chronicity of pain. Proper pain intervention requires measuring fear-avoidance responses an...
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Spotlight on SIG 6, Hearing and Hearing Disorders: Research and Diagnostics
Members of SIG 6 work to provide a forum for collaboration between researchers and clinicians to translate research into evidence-based practice related to hearing and balance. Read on for Keith Wolgemuth's first-hand experience. When did you join your ASHA special interest group (SIG)—and what made you want to join? I joined SIG 6 in early 2016, initially to complete a one-year term left by a colleague who needed to fulfill other professional commitments. Within three months, I was in a position to fill a vacancy as the SIG 6 associate coordinator, by virtue of being the only person on the committee at that time who did not have a job, so to speak! I agreed to stay on after completing my colleague's term because I wanted to learn more about how ASHA operates, and to give back...
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PKcGt0
The factors that influence oral health-related quality of life in young adults
Young adulthood is a time when subjects transform their role from a dependent child to an independent social identity. This cross-sectional study aimed to analyze the sociodemographic and clinical factors that...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PLIRZc
Validation of the Korean version of the avoidance endurance behavior questionnaire in patients with chronic pain
The avoidance-endurance model suggests both fear-avoidance responses and endurance-related responses could affect the chronicity of pain. Proper pain intervention requires measuring fear-avoidance responses an...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2xeJl3h
Spotlight on SIG 6, Hearing and Hearing Disorders: Research and Diagnostics
Members of SIG 6 work to provide a forum for collaboration between researchers and clinicians to translate research into evidence-based practice related to hearing and balance. Read on for Keith Wolgemuth's first-hand experience. When did you join your ASHA special interest group (SIG)—and what made you want to join? I joined SIG 6 in early 2016, initially to complete a one-year term left by a colleague who needed to fulfill other professional commitments. Within three months, I was in a position to fill a vacancy as the SIG 6 associate coordinator, by virtue of being the only person on the committee at that time who did not have a job, so to speak! I agreed to stay on after completing my colleague's term because I wanted to learn more about how ASHA operates, and to give back...
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Head And Neck Cancer Treatment Market Promising regions, Driver, Key Players, Technology, Trends and Forecast to ...
| Head And Neck Cancer Treatment Market Promising regions, Driver, Key Players, Technology, Trends and Forecast to ... Newszak (blog)Full coverage |
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The European Head and Neck Cancer Community Comes Together to Make Sense of This Rare Form of Cancer
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Zootherapeutic uses of wildmeat and associated products in the semiarid region of Brazil: general aspects and challenges for conservation
Hunting wildlife for medicinal purposes is a widespread practice throughout Brazil; however, studies about the animals used for zootherapeutic practices have been performed almost exclusively with traders (her...
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Zootherapeutic uses of wildmeat and associated products in the semiarid region of Brazil: general aspects and challenges for conservation
Hunting wildlife for medicinal purposes is a widespread practice throughout Brazil; however, studies about the animals used for zootherapeutic practices have been performed almost exclusively with traders (her...
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Evaluation of the vitros hiv combo 4th generation test for the identification of hiv infections
Antibody detection against Human Immunodeficiency Virus (HIV) is a commonly-used method for screening HIV infection. Over time, with the improvement of immunological techniques, several generations of tests for detection of anti-HIV antibodies have been developed. The first generation tests, which used an HIV lysate as the source of antigens for the test preparation, had some specificity problems that were minimized in second generation tests which used recombinant antigens (eg in Escherichia coli). (Source: Journal of Clinical Virology)
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VSIG-3 as a ligand of VISTA inhibits human T cell function.
This article is protected by copyright. All rights reserved. PMID: 30220083 [PubMed - as supplied by publisher] (Source: Immunology)
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Investigations on the constitutional types under consideration of anthropometric data, autonomic regulation and immunological parameters.
CONCLUSION: This study represents a first empirical approach toward the classification of anthroposophic constitutional types. PMID: 30219439 [PubMed - in process] (Source: Complementary Therapies in Medicine)
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Evaluation of the vitros hiv combo 4th generation test for the identification of hiv infections
Antibody detection against Human Immunodeficiency Virus (HIV) is a commonly-used method for screening HIV infection. Over time, with the improvement of immunological techniques, several generations of tests for detection of anti-HIV antibodies have been developed. The first generation tests, which used an HIV lysate as the source of antigens for the test preparation, had some specificity problems that were minimized in second generation tests which used recombinant antigens (eg in Escherichia coli). (Source: Journal of Clinical Virology)
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VSIG-3 as a ligand of VISTA inhibits human T cell function.
This article is protected by copyright. All rights reserved. PMID: 30220083 [PubMed - as supplied by publisher] (Source: Immunology)
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Feasibility of desensitizing children highly allergic to peanut by high‐dose oral immunotherapy
Allergy, Volume 0, Issue ja, -Not available-.
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Tolerability of iobitridol in patients with non‐immediate hypersensitivity reactions to iodinated contrast media
Allergy, Volume 0, Issue ja, -Not available-.
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Feasibility of desensitizing children highly allergic to peanut by high‐dose oral immunotherapy
Allergy, Volume 0, Issue ja, -Not available-.
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Tolerability of iobitridol in patients with non‐immediate hypersensitivity reactions to iodinated contrast media
Allergy, Volume 0, Issue ja, -Not available-.
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(HealthNewsDigest.com) - Summit, NJ -
| (HealthNewsDigest.com) - Summit, NJ - HealthNewsDigest.comFull coverage |
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Woman battling cancer to receive bone marrow transplant from her 14-year-old daughter
| Woman battling cancer to receive bone marrow transplant from her 14-year-old daughter KMOV.comFull coverage |
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(HealthNewsDigest.com) - Summit, NJ -
| (HealthNewsDigest.com) - Summit, NJ - HealthNewsDigest.comFull coverage |
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Woman battling cancer to receive bone marrow transplant from her 14-year-old daughter
| Woman battling cancer to receive bone marrow transplant from her 14-year-old daughter KMOV.comFull coverage |
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Characterization of Mycobacterial Induced Immunity in HIV-infected and Uninfected Individuals (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-923 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support innovative studies to identify and understand the immunological responses that mediate protection from Mycobacterium tuberculosis (Mtb) infection or following vaccination with Bacillus Calmette-Gurin (BCG) or investigational vaccines. Studies may focus on any stage of mycobacterial infection and may include HIV-infected or uninfected individuals. Development of novel functional assays to assess host response and inclusion of immune profiling and systems biology approaches are encouraged. This FOA seeks to stimulate innovative research in deciphering immune mechanisms in humans required for protection from Mtb infection or tuberculosis (TB) di...
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Characterization of Mycobacterial Induced Immunity in HIV-infected and Uninfected Individuals (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-923 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support innovative studies to identify and understand the immunological responses that mediate protection from Mycobacterium tuberculosis (Mtb) infection or following vaccination with Bacillus Calmette-Gurin (BCG) or investigational vaccines. Studies may focus on any stage of mycobacterial infection and may include HIV-infected or uninfected individuals. Development of novel functional assays to assess host response and inclusion of immune profiling and systems biology approaches are encouraged. This FOA seeks to stimulate innovative research in deciphering immune mechanisms in humans required for protection from Mtb infection or tuberculosis (TB) di...
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Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
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Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
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Spotlight on SIG 6, Hearing and Hearing Disorders: Research and Diagnostics
Members of SIG 6 work to provide a forum for collaboration between researchers and clinicians to translate research into evidence-based practice related to hearing and balance. Read on for Keith Wolgemuth's first-hand experience. When did you join your ASHA special interest group (SIG)—and what made you want to join? I joined SIG 6 in early 2016, initially to complete a one-year term left by a colleague who needed to fulfill other professional commitments. Within three months, I was in a position to fill a vacancy as the SIG 6 associate coordinator, by virtue of being the only person on the committee at that time who did not have a job, so to speak! I agreed to stay on after completing my colleague's term because I wanted to learn more about how ASHA operates, and to give back...
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Oticon Opn Hearing Aids Now Help Assess Hearing Health
Oticon, one of the big names in hearing aid products, is releasing a tool that helps people using hearing aids to learn more about their hearing health and to better understand how these devices are impacting their lives. The technology is available on the Oticon Opn hearing aids, including for patients that have already been using the devices. It's now a part of the company's ON App and Oticon compares the offering to wearable activity trackers, but specifically designed to assess one's hearing-related activities and participation in them. The HearingFitness software monitors the use of the Oticon Opn and the types of sound environments the patients find themselves, as well as the behaviors exhibited. Using this information, the software offers advice on how to improve h...
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Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
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Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
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The European Head and Neck Cancer Community Comes Together to Make Sense of This Rare Form of Cancer
| The European Head and Neck Cancer Community Comes Together to Make Sense of This Rare Form of Cancer PR Newswire (press release)No more out of county travel for head and neck cancer patients The Wiltshire Gazette and HeraldHead and Neck Cancer Treatment Market: Sales, Ex-factory Price, Revenue, Gross Margin Analysis 2017 Our Market ResearchFull coverage |
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Spotlight on SIG 6, Hearing and Hearing Disorders: Research and Diagnostics
Members of SIG 6 work to provide a forum for collaboration between researchers and clinicians to translate research into evidence-based practice related to hearing and balance. Read on for Keith Wolgemuth's first-hand experience. When did you join your ASHA special interest group (SIG)—and what made you want to join? I joined SIG 6 in early 2016, initially to complete a one-year term left by a colleague who needed to fulfill other professional commitments. Within three months, I was in a position to fill a vacancy as the SIG 6 associate coordinator, by virtue of being the only person on the committee at that time who did not have a job, so to speak! I agreed to stay on after completing my colleague's term because I wanted to learn more about how ASHA operates, and to give back...
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PKcGt0
Oticon Opn Hearing Aids Now Help Assess Hearing Health
Oticon, one of the big names in hearing aid products, is releasing a tool that helps people using hearing aids to learn more about their hearing health and to better understand how these devices are impacting their lives. The technology is available on the Oticon Opn hearing aids, including for patients that have already been using the devices. It's now a part of the company's ON App and Oticon compares the offering to wearable activity trackers, but specifically designed to assess one's hearing-related activities and participation in them. The HearingFitness software monitors the use of the Oticon Opn and the types of sound environments the patients find themselves, as well as the behaviors exhibited. Using this information, the software offers advice on how to improve h...
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Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
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Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
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The European Head and Neck Cancer Community Comes Together to Make Sense of This Rare Form of Cancer
| The European Head and Neck Cancer Community Comes Together to Make Sense of This Rare Form of Cancer PR Newswire (press release)No more out of county travel for head and neck cancer patients The Wiltshire Gazette and HeraldHead and Neck Cancer Treatment Market: Sales, Ex-factory Price, Revenue, Gross Margin Analysis 2017 Our Market ResearchFull coverage |
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7 Warning Signs of Thyroid Cancer
| 7 Warning Signs of Thyroid Cancer TAPinto.netFull coverage |
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7 Warning Signs of Thyroid Cancer
| 7 Warning Signs of Thyroid Cancer TAPinto.netFull coverage |
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Ambient Particulate Matter Linked to Emergency Asthma Care
Increase in asthma hospital visits with increasing ambient particulate matter in San Luis Valley (Source: Pulmonary Medicine News - Doctors Lounge)
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Experimental nasal influenza vaccine tested in kids, teens
(NIH/National Institute of Allergy and Infectious Diseases) An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit (VTEU) site at Saint Louis University, St. Louis, Missouri. The VTEU is funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. (Source: EurekAlert! - Infectious and Emerging Diseases)
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Ambient Particulate Matter Linked to Emergency Asthma Care
Increase in asthma hospital visits with increasing ambient particulate matter in San Luis Valley (Source: Pulmonary Medicine News - Doctors Lounge)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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Experimental nasal influenza vaccine tested in kids, teens
(NIH/National Institute of Allergy and Infectious Diseases) An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit (VTEU) site at Saint Louis University, St. Louis, Missouri. The VTEU is funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. (Source: EurekAlert! - Infectious and Emerging Diseases)
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Experimental nasal influenza vaccine tested in kids, teens
(NIH/National Institute of Allergy and Infectious Diseases) An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit (VTEU) site at Saint Louis University, St. Louis, Missouri. The VTEU is funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. (Source: EurekAlert! - Infectious and Emerging Diseases)
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Experimental nasal influenza vaccine tested in kids, teens
(NIH/National Institute of Allergy and Infectious Diseases) An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit (VTEU) site at Saint Louis University, St. Louis, Missouri. The VTEU is funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. (Source: EurekAlert! - Infectious and Emerging Diseases)
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From subconscious to conscious to artificial intelligence: A focus on electronic health records
Subba Rao BhavarajuNeurology India 2018 66(5):1270-1275 A paradigm shift in human evolution, from our predecessors, the 'hunter-gatherers' to the 'era of digital revolution', has made certain human skills more and more machine driven. This digital revolution has made possible a constant connectivity, wearable technologies, customized platforms, enormous data storage and cloud computing at high speeds, smart phones and apps, internet of things, artificial intelligence, telemedicine, etc. These have made real-time monitoring and interventions possible in healthcare. Most advanced countries have made electronic health records (EHR) mandatory. The Government of India has an agenda of Digital India and digital healthcare and might insist on EHR...
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From subconscious to conscious to artificial intelligence: A focus on electronic health records
Subba Rao BhavarajuNeurology India 2018 66(5):1270-1275 A paradigm shift in human evolution, from our predecessors, the 'hunter-gatherers' to the 'era of digital revolution', has made certain human skills more and more machine driven. This digital revolution has made possible a constant connectivity, wearable technologies, customized platforms, enormous data storage and cloud computing at high speeds, smart phones and apps, internet of things, artificial intelligence, telemedicine, etc. These have made real-time monitoring and interventions possible in healthcare. Most advanced countries have made electronic health records (EHR) mandatory. The Government of India has an agenda of Digital India and digital healthcare and might insist on EHR...
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Dental imaging of trabecular bone structure for systemic disorder screening: A systematic review
Oral Diseases, EarlyView. (Source: Oral Diseases)
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Oral and dental health care during pregnancy: Evaluating a theory ‐driven intervention
Oral Diseases, EarlyView. (Source: Oral Diseases)
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FIERCE for a cure: Natick boot camp raises money for cancer research
| FIERCE for a cure: Natick boot camp raises money for cancer research Wicked Local BelmontFull coverage |
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Dental imaging of trabecular bone structure for systemic disorder screening: A systematic review
Oral Diseases, EarlyView. (Source: Oral Diseases)
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7 Warning Signs of Thyroid Cancer
| 7 Warning Signs of Thyroid Cancer TAPinto.netFull coverage |
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Oral and dental health care during pregnancy: Evaluating a theory ‐driven intervention
Oral Diseases, EarlyView. (Source: Oral Diseases)
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FIERCE for a cure: Natick boot camp raises money for cancer research
| FIERCE for a cure: Natick boot camp raises money for cancer research Wicked Local BelmontFull coverage |
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7 Warning Signs of Thyroid Cancer
| 7 Warning Signs of Thyroid Cancer TAPinto.netFull coverage |
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NIH and Children ’s National partner to advance pediatric clinical research
Inaugural symposium highlights collaboration in allergic, immunologic and infectious disease research. (Source: National Institutes of Health (NIH) News Releases)
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NIH and Children ’s National partner to advance pediatric clinical research
Inaugural symposium highlights collaboration in allergic, immunologic and infectious disease research. (Source: National Institutes of Health (NIH) News Releases)
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Is the Vazirani-Akinosi nerve block a better technique than the conventional inferior alveolar nerve block for beginners?
To compare the efficacy and comfort of the inferior alveolar nerve block and the Vazirani-Akinosi block, when given by dental trainees.
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A Retrospective Study of Patient Outcomes Following Temporomandibular Joint Replacement with Alloplastic Total Joint Prosthesis at Massachusetts General Hospital
Disorders of the temporomandibular joint (TMJ) occur frequently, with a prevalence of 15-18%. Total joint replacement (TJR) surgery is indicated for severe joint damage associated with impaired function, pain, or occlusal change where other treatments have been unsuccessful.
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Is Tongue-Lip Adhesion or Mandibular Distraction More Effective in Relieving Obstructive Apnea in Infants with Robin Sequence?
Tongue-lip adhesion (TLA) and mandibular distraction osteogenesis (MDO) are the most common operations for obstructive apnea (OA) in infants with Robin sequence (RS). The purpose of this study is to compare early outcomes of TLA and MDO on resolution of OA.
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A method for addressing right upper lobe obstruction with right-sided double-lumen endobronchial tubes during surgery: a randomized controlled trial
Abstract
Background
A right-sided double-lumen tube (R-DLT) tends to obstruct the right upper lobe intraoperatively due to anatomical distortion during surgery. If the R-DLT is poorly matched with the patient's airway anatomy, it will not be possible to correctly replace the tube with a fiberoptic bronchoscope (FOB). In our study, we aimed to explore an efficient method for difficult repositioning caused by right upper lobe occlusion during surgery: repositioning the R-DLT from the right main bronchus into the left main bronchus. The current study was designed to assess the efficacy and safety of this method.
Methods
Sixty adult patients scheduled to undergo left-sided thoracic surgery were randomly assigned to two groups. With the patient in the right lateral position during surgery, the R-DLT was pulled back to the trachea while being rotated 90° clockwise; it was then either rotated 90° clockwise for placement into the left main bronchus (Group L) or rotated 90° anticlockwise and returned to the right main bronchus (Group R) using FOB guidance. The primary outcomes included clinical performance, which was measured by intubation time, and the quality of lung collapse. A secondary outcome was safety, which was determined according to bronchial injury and vocal cord injury.
Results
The median intubation time (IQR [range]) required for placement of a R-DLT into the left main bronchus was shorter than the time required for placement into the right main bronchus (15.0 s [IQR, 12.0 to 20.0 s]) vs 23.5 s [IQR, 14.5 to 65.8 s], P = 0.005). The groups showed comparable overall results for the quality of lung collapse during the total period of one-lung ventilation (P = 1.000). The numbers of patients with bronchial injuries or vocal cord injuries were also comparable between groups (Group R, 11/30 vs. Group L 8/30, P = 0.580 for bronchus injuries; Group R, 15/30 vs. Group L 13/30, P = 0.796 for vocal cord injuries).
Conclusions
Repositioning a R-DLT from the right main bronchus into the left main bronchus had good clinical performance without causing additional injury. This may be an efficient method for the difficult repositioning of a R-DLT due to right upper lobe occlusion during surgery.
Trial registration
Chinese Clinical Trial Registry, ChiCTR-IPR-15006933, registered on 15 August 2015.
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Is the Vazirani-Akinosi nerve block a better technique than the conventional inferior alveolar nerve block for beginners?
To compare the efficacy and comfort of the inferior alveolar nerve block and the Vazirani-Akinosi block, when given by dental trainees.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OzsDCg
A Retrospective Study of Patient Outcomes Following Temporomandibular Joint Replacement with Alloplastic Total Joint Prosthesis at Massachusetts General Hospital
Disorders of the temporomandibular joint (TMJ) occur frequently, with a prevalence of 15-18%. Total joint replacement (TJR) surgery is indicated for severe joint damage associated with impaired function, pain, or occlusal change where other treatments have been unsuccessful.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2NRjvvJ
Is Tongue-Lip Adhesion or Mandibular Distraction More Effective in Relieving Obstructive Apnea in Infants with Robin Sequence?
Tongue-lip adhesion (TLA) and mandibular distraction osteogenesis (MDO) are the most common operations for obstructive apnea (OA) in infants with Robin sequence (RS). The purpose of this study is to compare early outcomes of TLA and MDO on resolution of OA.
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24 HOUR ALLERGY (Cetirizine Hcl) Capsule [Walgreens]
Updated Date: Sep 14, 2018 EST (Source: DailyMed Drug Label Updates)
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24 HOUR ALLERGY (Cetirizine Hcl) Capsule [Walgreens]
Updated Date: Sep 14, 2018 EST (Source: DailyMed Drug Label Updates)
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Dangers of Increased Earwax With Age
Earwax protects our delicate hearing mechanism from dirt and other airborne particles. And any audiologist or physician will tell you there's typically no need for most people to clean the goop out of our ears. (In fact, improper cleaning could injure the eardrum and ear canal.) However, as people get older, the chances of potentially harmful earwax (cerumen) buildup increase. According to an article from CNN, approximately two-thirds of the more than 2 million people living in skilled nursing and assisted living facilities in the U.S. might have a severe buildup of earwax called impaction. "The excessive amount [of earwax] can cause hearing loss or ringing in your ears, says audiologist Jackie Clark in the article. "Some people experience vertigo, which increases the risk o...
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Dangers of Increased Earwax With Age
Earwax protects our delicate hearing mechanism from dirt and other airborne particles. And any audiologist or physician will tell you there's typically no need for most people to clean the goop out of our ears. (In fact, improper cleaning could injure the eardrum and ear canal.) However, as people get older, the chances of potentially harmful earwax (cerumen) buildup increase. According to an article from CNN, approximately two-thirds of the more than 2 million people living in skilled nursing and assisted living facilities in the U.S. might have a severe buildup of earwax called impaction. "The excessive amount [of earwax] can cause hearing loss or ringing in your ears, says audiologist Jackie Clark in the article. "Some people experience vertigo, which increases the risk o...
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Evidence of Cross-Reactivity between Different Seed Storage Proteins from Hazelnut ( < b > < i > Corylus avellana < /i > < /b > ) and Walnut ( < b > < i > Juglans regia < /i > < /b > ) Using Recombinant Allergen Proteins
This study aimed to ascertain the cross-reactivity between walnut and hazelnut seed storage proteins using recombinant allergens. Sera from 13 consecutive patients with severe primary walnut and/or hazelnut allergy and hypersensitive to both nuts were studied. IgE specific for rCor a 9, rCor a 14, and rJug r 1 was measured, and inhibition experiments were carried out by measuring IgE reactivity after absorption of patients ' sera with freshly prepared walnut extract. All 13 sera showed strong IgE reactivity against walnut 2S albumin, Jug r 1, 12 reacted to hazelnut 2S albumin, Cor a 14, and 8 to the hazelnut legumin, Cor a 9. In inhibition experiments, absorption of sera with whole walnut extract led to the complete disappearance of IgE reactivity to Jug r 1 in 12/13 cases, as expected, ...
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Evidence of Cross-Reactivity between Different Seed Storage Proteins from Hazelnut ( < b > < i > Corylus avellana < /i > < /b > ) and Walnut ( < b > < i > Juglans regia < /i > < /b > ) Using Recombinant Allergen Proteins
This study aimed to ascertain the cross-reactivity between walnut and hazelnut seed storage proteins using recombinant allergens. Sera from 13 consecutive patients with severe primary walnut and/or hazelnut allergy and hypersensitive to both nuts were studied. IgE specific for rCor a 9, rCor a 14, and rJug r 1 was measured, and inhibition experiments were carried out by measuring IgE reactivity after absorption of patients ' sera with freshly prepared walnut extract. All 13 sera showed strong IgE reactivity against walnut 2S albumin, Jug r 1, 12 reacted to hazelnut 2S albumin, Cor a 14, and 8 to the hazelnut legumin, Cor a 9. In inhibition experiments, absorption of sera with whole walnut extract led to the complete disappearance of IgE reactivity to Jug r 1 in 12/13 cases, as expected, ...
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NIH and Children ’s National partner to advance pediatric clinical research
Inaugural symposium highlights collaboration in allergic, immunologic and infectious disease research. (Source: National Institutes of Health (NIH) News Releases)
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NIH and Children ’s National partner to advance pediatric clinical research
Inaugural symposium highlights collaboration in allergic, immunologic and infectious disease research. (Source: National Institutes of Health (NIH) News Releases)
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Caries in children with lactose intolerance and cow's milk protein allergy
Abstract Dental caries in 5-to-8-year-old children with cow's milk protein allergy (CMPA) and lactose intolerance (LI), their treatment needs, and the consumption of milk-based products and milk derivatives by these patients were investigated. A cross-sectional study was undertaken with 200 children in southern Brazil in 2017. The clinical examination was based on the World Health Organization criteria and a questionnaire was sent to parents or legal guardians to collect information on the children's food intake, pre-existing systemic diseases, medication use, and CMPA and LI. Standardization was performed to verify concordance among examiners (kappa = 0.96). Caries prevalence was 67.50% in children with CMPA or LI, but 34.37% in those without these conditions. The mean dmft (decayed, miss...
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Caries in children with lactose intolerance and cow's milk protein allergy
Abstract Dental caries in 5-to-8-year-old children with cow's milk protein allergy (CMPA) and lactose intolerance (LI), their treatment needs, and the consumption of milk-based products and milk derivatives by these patients were investigated. A cross-sectional study was undertaken with 200 children in southern Brazil in 2017. The clinical examination was based on the World Health Organization criteria and a questionnaire was sent to parents or legal guardians to collect information on the children's food intake, pre-existing systemic diseases, medication use, and CMPA and LI. Standardization was performed to verify concordance among examiners (kappa = 0.96). Caries prevalence was 67.50% in children with CMPA or LI, but 34.37% in those without these conditions. The mean dmft (decayed, miss...
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2D7bSxb
Is the Vazirani-Akinosi nerve block a better technique than the conventional inferior alveolar nerve block for beginners?
To compare the efficacy and comfort of the inferior alveolar nerve block and the Vazirani-Akinosi block, when given by dental trainees.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OzsDCg
A Retrospective Study of Patient Outcomes Following Temporomandibular Joint Replacement with Alloplastic Total Joint Prosthesis at Massachusetts General Hospital
Disorders of the temporomandibular joint (TMJ) occur frequently, with a prevalence of 15-18%. Total joint replacement (TJR) surgery is indicated for severe joint damage associated with impaired function, pain, or occlusal change where other treatments have been unsuccessful.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2NRjvvJ
Is Tongue-Lip Adhesion or Mandibular Distraction More Effective in Relieving Obstructive Apnea in Infants with Robin Sequence?
Tongue-lip adhesion (TLA) and mandibular distraction osteogenesis (MDO) are the most common operations for obstructive apnea (OA) in infants with Robin sequence (RS). The purpose of this study is to compare early outcomes of TLA and MDO on resolution of OA.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OzsqPu
Is the Vazirani-Akinosi nerve block a better technique than the conventional inferior alveolar nerve block for beginners?
To compare the efficacy and comfort of the inferior alveolar nerve block and the Vazirani-Akinosi block, when given by dental trainees.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OzsDCg
A Retrospective Study of Patient Outcomes Following Temporomandibular Joint Replacement with Alloplastic Total Joint Prosthesis at Massachusetts General Hospital
Disorders of the temporomandibular joint (TMJ) occur frequently, with a prevalence of 15-18%. Total joint replacement (TJR) surgery is indicated for severe joint damage associated with impaired function, pain, or occlusal change where other treatments have been unsuccessful.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2NRjvvJ
7 Warning Signs of Thyroid Cancer
| 7 Warning Signs of Thyroid Cancer TAPinto.netFull coverage |
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Association Health Plans Can Help Small Businesses Offer Coverage
But AHPs may undermine ACA marketplace, as they are not required to comply with ACA regulations (Source: The Doctors Lounge - Psychiatry)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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7 Warning Signs of Thyroid Cancer
| 7 Warning Signs of Thyroid Cancer TAPinto.netFull coverage |
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Detection of high‐grade dysplasia, carcinoma in situ and squamous cell carcinoma in the upper aerodigestive tract: recommendations for optimal use and interpretation of Narrow Band Imaging
Clinical Otolaryngology, Volume 0, Issue ja, -Not available-.
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A mixed methods study of the management of hearing loss associated with otitis media with effusion in children with Down syndrome
Clinical Otolaryngology, Volume 0, Issue ja, -Not available-.
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Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
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Detection of high‐grade dysplasia, carcinoma in situ and squamous cell carcinoma in the upper aerodigestive tract: recommendations for optimal use and interpretation of Narrow Band Imaging
Clinical Otolaryngology, Volume 0, Issue ja, -Not available-.
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A mixed methods study of the management of hearing loss associated with otitis media with effusion in children with Down syndrome
Clinical Otolaryngology, Volume 0, Issue ja, -Not available-.
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Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PJzhG6
A prospective, randomized, single‐blinded trial for improving health outcomes in rhinology by the use of personalized video recordings
International Forum of Allergy &Rhinology, EarlyView.
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A prospective, randomized, single‐blinded trial for improving health outcomes in rhinology by the use of personalized video recordings
International Forum of Allergy &Rhinology, EarlyView.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QEfJ7j
Estradiol ‐regulated innate antiviral responses of human endometrial stromal fibroblasts
American Journal of Reproductive Immunology, EarlyView. (Source: American Journal of Reproductive Immunology)
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Decidualization modulates a signal transduction system via protease ‐activated receptor‐1 in endometrial stromal cells
American Journal of Reproductive Immunology, EarlyView. (Source: American Journal of Reproductive Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2pdGvXM
A prospective, randomized, single ‐blinded trial for improving health outcomes in rhinology by the use of personalized video recordings
International Forum of Allergy&Rhinology, EarlyView. (Source: International Forum of Allergy and Rhinology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OsJqa2
Plasmacytoma variant translocation 1 (PVT1) regulates trophoblast viability, proliferation, and migration and is downregulated in spontaneous abortion
American Journal of Reproductive Immunology, EarlyView. (Source: American Journal of Reproductive Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2pg7jGP
Allergic Acute Coronary Syndrome (Kounis Syndrome) in a Young Woman During Spinal Anesthesia: A Case Report
We present a case of a young woman who experienced attacks of dyspnea, hypoxemia, and hypotension during and after spinal anesthesia. Based on the pattern of clinical symptoms and laboratory findings, she was retrospectively diagnosed with Kounis syndrome, even though no apparent trigger of hypersensitivity was found. (Source: A&A Case Reports)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OxCHM3
Evidence of Cross-Reactivity between Different Seed Storage Proteins from Hazelnut ( < b > < i > Corylus avellana < /i > < /b > ) and Walnut ( < b > < i > Juglans regia < /i > < /b > ) Using Recombinant Allergen Proteins
This study aimed to ascertain the cross-reactivity between walnut and hazelnut seed storage proteins using recombinant allergens. Sera from 13 consecutive patients with severe primary walnut and/or hazelnut allergy and hypersensitive to both nuts were studied. IgE specific for rCor a 9, rCor a 14, and rJug r 1 was measured, and inhibition experiments were carried out by measuring IgE reactivity after absorption of patients ' sera with freshly prepared walnut extract. All 13 sera showed strong IgE reactivity against walnut 2S albumin, Jug r 1, 12 reacted to hazelnut 2S albumin, Cor a 14, and 8 to the hazelnut legumin, Cor a 9. In inhibition experiments, absorption of sera with whole walnut extract led to the complete disappearance of IgE reactivity to Jug r 1 in 12/13 cases, as expected, ...
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2pcXMAp
Estradiol ‐regulated innate antiviral responses of human endometrial stromal fibroblasts
American Journal of Reproductive Immunology, EarlyView. (Source: American Journal of Reproductive Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OzaTa2
A prospective, randomized, single ‐blinded trial for improving health outcomes in rhinology by the use of personalized video recordings
International Forum of Allergy&Rhinology, EarlyView. (Source: International Forum of Allergy and Rhinology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OsJqa2
Plasmacytoma variant translocation 1 (PVT1) regulates trophoblast viability, proliferation, and migration and is downregulated in spontaneous abortion
American Journal of Reproductive Immunology, EarlyView. (Source: American Journal of Reproductive Immunology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2pg7jGP
Allergic Acute Coronary Syndrome (Kounis Syndrome) in a Young Woman During Spinal Anesthesia: A Case Report
We present a case of a young woman who experienced attacks of dyspnea, hypoxemia, and hypotension during and after spinal anesthesia. Based on the pattern of clinical symptoms and laboratory findings, she was retrospectively diagnosed with Kounis syndrome, even though no apparent trigger of hypersensitivity was found. (Source: A&A Case Reports)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OxCHM3
Significance of neck dissection for the treatment of clinically-evident medullary thyroid carcinomas: A systematic review
The survival benefit of prophylactic lateral neck dissection in medullary thyroid carcinomas remains unclear; thus, recent clinical guidelines have deferred the recommendation of lateral neck dissection. This review is to assess the role of lateral neck dissection in treatment of clinically overt medullary thyroid carcinoma.
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Significance of neck dissection for the treatment of clinically-evident medullary thyroid carcinomas: A systematic review
The survival benefit of prophylactic lateral neck dissection in medullary thyroid carcinomas remains unclear; thus, recent clinical guidelines have deferred the recommendation of lateral neck dissection. This review is to assess the role of lateral neck dissection in treatment of clinically overt medullary thyroid carcinoma.
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Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
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Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
| Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023 Daily Industry ReportsFull coverage |
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2MGATia
Do These Things Right Now to Help Prevent Cancer
| Do These Things Right Now to Help Prevent Cancer Newswise (press release)Full coverage |
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2PJzhG6
Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
| Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023 Daily Industry ReportsFull coverage |
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2MGATia
Association Health Plans Can Help Small Businesses Offer Coverage
But AHPs may undermine ACA marketplace, as they are not required to comply with ACA regulations (Source: The Doctors Lounge - Psychiatry)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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< b > < i > In Silico < /i > < /b > Identification and < b > < i > in Vitro < /i > < /b > Analysis of B and T-Cell Epitopes of the Black Turtle Bean ( < b > < i > Phaseolus Vulgaris L < /i > < /b > .) Lectin
Conclusion: The present approach can be applied for the identification of epitopes in novel allergen proteins and thus for designing diagnostics and therapies in lectin allergy.Cell Physiol Biochem 2018;49:1600 –1614 (Source: Cellular Physiology and Biochemistry)
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Comparative Analysis of Biological and Functional Properties of Bone Marrow Mesenchymal Stromal Cells Expanded in Media with Different Platelet Lysate Content
Due to their ability to induce immunological tolerance in the recipient, mesenchymal stromal cells (MSCs) have been utilized in the treatment of various hematological and immune- and inflammation-mediated diseases. The clinical application of MSCs implies prior in vitro expansion that usually includes the use of fetal bovine serum (FBS). The present study evaluated the effect of different platelet lysate (PL) media content on the biological properties of MSCs. MSCs were isolated from the bone marrow of 13 healthy individuals and subsequently expanded in three different culture conditions (10% PL, 5% PL, 10% FBS) during 4 passages. The cells cultured in different conditions had comparable immunophenotype, clonogenic potential, and differentiation capacity. However, MSC growth was significan...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OxskI0
Comparative Analysis of Biological and Functional Properties of Bone Marrow Mesenchymal Stromal Cells Expanded in Media with Different Platelet Lysate Content
Due to their ability to induce immunological tolerance in the recipient, mesenchymal stromal cells (MSCs) have been utilized in the treatment of various hematological and immune- and inflammation-mediated diseases. The clinical application of MSCs implies prior in vitro expansion that usually includes the use of fetal bovine serum (FBS). The present study evaluated the effect of different platelet lysate (PL) media content on the biological properties of MSCs. MSCs were isolated from the bone marrow of 13 healthy individuals and subsequently expanded in three different culture conditions (10% PL, 5% PL, 10% FBS) during 4 passages. The cells cultured in different conditions had comparable immunophenotype, clonogenic potential, and differentiation capacity. However, MSC growth was significan...
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OxskI0
The identification of autoantigens in mucous membrane pemphigoid using immortalized oral mucosal keratinocytes
Journal of Oral Pathology &Medicine, Volume 0, Issue ja, -Not available-.
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2pgKJhq
The identification of autoantigens in mucous membrane pemphigoid using immortalized oral mucosal keratinocytes
Journal of Oral Pathology &Medicine, Volume 0, Issue ja, -Not available-.
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Update on multiparametric MRI of urinary bladder cancer
Journal of Magnetic Resonance Imaging, EarlyView.
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Feasibility, efficacy, and safety of percutaneous MR‐guided ablation of small (≤12 mm) hepatic malignancies
Journal of Magnetic Resonance Imaging, EarlyView.
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Update on multiparametric MRI of urinary bladder cancer
Journal of Magnetic Resonance Imaging, EarlyView.
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Feasibility, efficacy, and safety of percutaneous MR‐guided ablation of small (≤12 mm) hepatic malignancies
Journal of Magnetic Resonance Imaging, EarlyView.
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Differentiated Thyroid Cancer Therapeutics Market 2018-2025: Market Positioning (Brand Strategy, Pricing Strategy ...
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There is no 'good' cancer
| There is no 'good' cancer Quad-Cities OnlineFull coverage |
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No, there is no such thing as a 'good cancer'
| No, there is no such thing as a 'good cancer' Quad-Cities OnlineFull coverage |
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Differentiated Thyroid Cancer Therapeutics Market 2018-2025: Market Positioning (Brand Strategy, Pricing Strategy ...
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There is no 'good' cancer
| There is no 'good' cancer Quad-Cities OnlineFull coverage |
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2pdtBsO
No, there is no such thing as a 'good cancer'
| No, there is no such thing as a 'good cancer' Quad-Cities OnlineFull coverage |
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Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
| Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023 Daily Industry ReportsFull coverage |
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2MGATia
Limitations in and Solutions for Improving the Functionality of Picture Archiving and Communication System: an Exploratory Study of PACS Professionals’ Perspectives
Abstract
Picture Archiving and Communication System (PACS) technology is evolving leading to improvements in the PACS functionality. However, the needs and expectations of PACS users are increasing to cope with the rising demands for improving the workflow and enhancing efficiency in healthcare. The aim was to study the limitations in the current generation of PACS and solutions for improving PACS functionality. This was a longitudinal online observational study of the perspectives of PACS professionals accessed through four online discussion groups on PACS using the LinkedIn network. In this exploratory study, the methodology involved a thematic analysis of qualitative data comprising 250 online posts/comments made by 124 unique PACS professionals collected between January 2014 and December 2015. Participants were mostly male (n = 119, 96%) from the North America (n = 88, 71%). Key themes on limitations in the current generation of PACS were image transmission problems, network and hardware issues, difficulties in changing specific settings, issues in hardcoded Digital Imaging and Communication in Medicine attributes, and problems in implementing open source PACS. Main themes on solutions for improving PACS functionality were the integration of multisite PACS, multimedia for PACS, web-based PACS, medical image viewer, open source PACS, PACS on mobile phones, vendor neutral archives for PACS, speech recognition and integration in PACS, PACS backup and recovery, and connecting PACS with other hospital systems. Despite ongoing technological developments, the current generation of PACS has limitations that affect PACS functionality leading to unmet needs and requirements of PACS users, which could impact workflow and efficiency in healthcare.
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European photopatch test baseline series: A 3‐year experience
Contact Dermatitis, EarlyView.
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Limitations in and Solutions for Improving the Functionality of Picture Archiving and Communication System: an Exploratory Study of PACS Professionals’ Perspectives
Abstract
Picture Archiving and Communication System (PACS) technology is evolving leading to improvements in the PACS functionality. However, the needs and expectations of PACS users are increasing to cope with the rising demands for improving the workflow and enhancing efficiency in healthcare. The aim was to study the limitations in the current generation of PACS and solutions for improving PACS functionality. This was a longitudinal online observational study of the perspectives of PACS professionals accessed through four online discussion groups on PACS using the LinkedIn network. In this exploratory study, the methodology involved a thematic analysis of qualitative data comprising 250 online posts/comments made by 124 unique PACS professionals collected between January 2014 and December 2015. Participants were mostly male (n = 119, 96%) from the North America (n = 88, 71%). Key themes on limitations in the current generation of PACS were image transmission problems, network and hardware issues, difficulties in changing specific settings, issues in hardcoded Digital Imaging and Communication in Medicine attributes, and problems in implementing open source PACS. Main themes on solutions for improving PACS functionality were the integration of multisite PACS, multimedia for PACS, web-based PACS, medical image viewer, open source PACS, PACS on mobile phones, vendor neutral archives for PACS, speech recognition and integration in PACS, PACS backup and recovery, and connecting PACS with other hospital systems. Despite ongoing technological developments, the current generation of PACS has limitations that affect PACS functionality leading to unmet needs and requirements of PACS users, which could impact workflow and efficiency in healthcare.
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Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
| Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023 Daily Industry ReportsFull coverage |
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European photopatch test baseline series: A 3‐year experience
Contact Dermatitis, EarlyView.
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Shigella and Enteroinvasive Escherichia Coli.
Authors: Belotserkovsky I, Sansonetti PJ Abstract Shigella and enteroinvasive Escherichia coli (EIEC) are gram-negative bacteria responsible for bacillary dysentery (shigellosis) in humans, which is characterized by invasion and inflammatory destruction of the human colonic epithelium. Different EIEC and Shigella subgroups rose independently from commensal E. coli through patho-adaptive evolution that included loss of functional genes interfering with the virulence and/or with the intracellular lifestyle of the bacteria, as well as acquisition of genetic elements harboring virulence genes. Among the latter is the large virulence plasmid encoding for a type three secretion system (T3SS), which enables translocation of virulence proteins (effectors) from the bacterium directly into t...
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Shigella and Enteroinvasive Escherichia Coli.
Authors: Belotserkovsky I, Sansonetti PJ Abstract Shigella and enteroinvasive Escherichia coli (EIEC) are gram-negative bacteria responsible for bacillary dysentery (shigellosis) in humans, which is characterized by invasion and inflammatory destruction of the human colonic epithelium. Different EIEC and Shigella subgroups rose independently from commensal E. coli through patho-adaptive evolution that included loss of functional genes interfering with the virulence and/or with the intracellular lifestyle of the bacteria, as well as acquisition of genetic elements harboring virulence genes. Among the latter is the large virulence plasmid encoding for a type three secretion system (T3SS), which enables translocation of virulence proteins (effectors) from the bacterium directly into t...
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Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
| Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023 Daily Industry ReportsFull coverage |
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Interpace Diagnostics Supports Research Efforts of Pancreatic and Thyroid Cancer Patient Advocacy Groups
| Interpace Diagnostics Supports Research Efforts of Pancreatic and Thyroid Cancer Patient Advocacy Groups NasdaqFull coverage |
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Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023
| Head And Neck Cancer Therapeutics In Asia-Pacific Market Will Grow At A CAGR of 6.9% in 2023 Daily Industry ReportsFull coverage |
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Interpace Diagnostics Supports Research Efforts of Pancreatic and Thyroid Cancer Patient Advocacy Groups
| Interpace Diagnostics Supports Research Efforts of Pancreatic and Thyroid Cancer Patient Advocacy Groups NasdaqFull coverage |
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Oral exfoliative cytology and corrosion of metal piercings. Tissue implications
Abstract
Objectives
A group of adolescents with oral piercings was studied to determine the presence of metallic particles in cells exfoliated from the mucosa surrounding their metal oral piercings and the association between such particles and the metal jewelry, and to evaluate subsequent tissue implications.
Materials and methods
Sixteen teenage patients who had tongue and/or lip piercings were included. The clinical features of the oral mucosa and lip skin were evaluated. Exfoliative cytology was performed in the area surrounding the piercing. The surface of used and unused jewelry was studied by scanning electron microscopy and energy dispersive X-ray analysis.
Results
Hyperplastic, leukoedematous, and lichenoid lesions were observed in the mucosa, as well as lesions associated with metallosis of the lip skin. Cytological smears showed the presence of particles inside the epithelial cells; the particles were found to contain aluminum, tungsten, and molybdenum. In one case requiring surgical removal of the piercing, histological examination of the tissue associated with the piece of jewelry showed the presence particles containing aluminum, iron, and tin inside multinucleated giant cells. Although surface finish defects were observed on both unused and used piercing jewelry, they were more evident on the used pieces.
Conclusions
Ion particles are released from the metal piercings and could have been adjuvant factors in the development of the observed lesions. Cells exfoliated from the oral mucosa surrounding metal piercings may serve as bioindicators of corrosion processes.
Clinical relevance
We propose the use of exfoliative cytology to monitor corrosion processes and for routine clinical follow up.
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Dentinal tubule penetration of AH Plus, BC Sealer and a novel tricalcium silicate sealer: a confocal laser scanning microscopy study
Abstract
Objectives
The aim of this in vitro study was to assess the dentinal tubule penetration of three different sealers, AH Plus, BC Sealer and a novel tricalcium silicate sealer (NTS).
Materials and methods
Ninety-six human maxillary central incisors were divided into three experimental groups (n = 32) and were filled with gutta-percha using a single-cone technique in conjunction with one of the three sealers: AH Plus, BC Sealer or NTS. The roots in each group were cross-sectioned at 1 and 5 mm from the root apex, and the surfaces were examined under confocal laser scanning microscopy (CLSM). The sealer penetration depths were measured at their maximum depths and at four circumferential depths (12, 3, 6 and 9 o'clock) and were evaluated using ImageJ software (ImageJ, NIH).
Results
The maximum and mean penetration depths were significantly higher at 5 mm compared to 1 mm from the apex in the AH Plus (p < 0.001), BC Sealer (p < 0.001) and NTS groups (p < 0.001). No significant difference was observed between the groups at 1 mm for both parameters. The maximum and mean penetration depths were significantly lower at 5 mm for AH Plus compared with the other two groups (p = 0.012).
Conclusions
Within the study limitations, the BC Sealer and NTS demonstrated better tubule penetration results than the AH Plus sealer.
Clinical relevance
Although no study has confirmed a relationship between the penetration depth of root canal sealers and the prevention of apical periodontitis, dentinal tubule sealer penetration may improve obturation quality.
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Oral exfoliative cytology and corrosion of metal piercings. Tissue implications
Abstract
Objectives
A group of adolescents with oral piercings was studied to determine the presence of metallic particles in cells exfoliated from the mucosa surrounding their metal oral piercings and the association between such particles and the metal jewelry, and to evaluate subsequent tissue implications.
Materials and methods
Sixteen teenage patients who had tongue and/or lip piercings were included. The clinical features of the oral mucosa and lip skin were evaluated. Exfoliative cytology was performed in the area surrounding the piercing. The surface of used and unused jewelry was studied by scanning electron microscopy and energy dispersive X-ray analysis.
Results
Hyperplastic, leukoedematous, and lichenoid lesions were observed in the mucosa, as well as lesions associated with metallosis of the lip skin. Cytological smears showed the presence of particles inside the epithelial cells; the particles were found to contain aluminum, tungsten, and molybdenum. In one case requiring surgical removal of the piercing, histological examination of the tissue associated with the piece of jewelry showed the presence particles containing aluminum, iron, and tin inside multinucleated giant cells. Although surface finish defects were observed on both unused and used piercing jewelry, they were more evident on the used pieces.
Conclusions
Ion particles are released from the metal piercings and could have been adjuvant factors in the development of the observed lesions. Cells exfoliated from the oral mucosa surrounding metal piercings may serve as bioindicators of corrosion processes.
Clinical relevance
We propose the use of exfoliative cytology to monitor corrosion processes and for routine clinical follow up.
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Dentinal tubule penetration of AH Plus, BC Sealer and a novel tricalcium silicate sealer: a confocal laser scanning microscopy study
Abstract
Objectives
The aim of this in vitro study was to assess the dentinal tubule penetration of three different sealers, AH Plus, BC Sealer and a novel tricalcium silicate sealer (NTS).
Materials and methods
Ninety-six human maxillary central incisors were divided into three experimental groups (n = 32) and were filled with gutta-percha using a single-cone technique in conjunction with one of the three sealers: AH Plus, BC Sealer or NTS. The roots in each group were cross-sectioned at 1 and 5 mm from the root apex, and the surfaces were examined under confocal laser scanning microscopy (CLSM). The sealer penetration depths were measured at their maximum depths and at four circumferential depths (12, 3, 6 and 9 o'clock) and were evaluated using ImageJ software (ImageJ, NIH).
Results
The maximum and mean penetration depths were significantly higher at 5 mm compared to 1 mm from the apex in the AH Plus (p < 0.001), BC Sealer (p < 0.001) and NTS groups (p < 0.001). No significant difference was observed between the groups at 1 mm for both parameters. The maximum and mean penetration depths were significantly lower at 5 mm for AH Plus compared with the other two groups (p = 0.012).
Conclusions
Within the study limitations, the BC Sealer and NTS demonstrated better tubule penetration results than the AH Plus sealer.
Clinical relevance
Although no study has confirmed a relationship between the penetration depth of root canal sealers and the prevention of apical periodontitis, dentinal tubule sealer penetration may improve obturation quality.
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Progenics Announces Addition of AZEDRA® (iobenguane I 131) to National Comprehensive Cancer Network ...
| Progenics Announces Addition of AZEDRA® (iobenguane I 131) to National Comprehensive Cancer Network ... GlobeNewswire (press release)Full coverage |
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Progenics Announces Addition of AZEDRA® (iobenguane I 131) to National Comprehensive Cancer Network ...
| Progenics Announces Addition of AZEDRA® (iobenguane I 131) to National Comprehensive Cancer Network ... GlobeNewswire (press release)Full coverage |
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Fall for apples
| Fall for apples Brainerd DispatchFull coverage |
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Fall for apples
| Fall for apples Brainerd DispatchFull coverage |
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Inhibition of Aeromonas hydrophila-induced intestinal inflammation and mucosal barrier function damage in crucian carp by oral administration of Lactococcus lactis
This study explored the immunomodulatory effect and inhibition effects of the candidate probiotic Lactococcus lactis 16-7, which was isolated from crucian carp, on Aeromonas hydrophila infection in crucian carp. The experimental fish were divided into two groups; one was fed a diet supplemented with L. lactis, while the other was fed the control probiotic-free diet. After feeding for 42 d with the experimental diets, the fish that received the diet supplemented with probiotics exhibited a significantly enhanced serum superoxide dismutase activity, phagocytic activities of innate immune cells, and the expression levels of immune-related genes [interferon-γ (INF-γ), interleukin-1β (IL-1β), interleukin-11 (IL-11), tumour necrosis factor α (TNF-α) and myeloid differentiation factor 88 ...
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Local specific Immunoglobulin E among patients with nonallergic rhinitis: a systematic review.
CONCLUSION: NAR with positive allergy history suggests presence of nspIgE. These patients warrant further allergology evaluation to confirm localized nasal allergy, as they benefit from allergy therapy such as immunotherapy. PMID: 30219822 [PubMed - as supplied by publisher] (Source: Rhinology)
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Aerial fungal spectrum of Kolkata, India, along with their allergenic impact on the public health: a quantitative and qualitative evaluation
AbstractAirborne fungal spores are well documented to trigger respiratory allergy. The present study provides baseline information on the quantitative and qualitative aspects of aerospores for the first time in a typical urban area of Kolkata metropolis, India. An aeromonitoring was performed by Burkard volumetric 7-day sampler for two consecutive years (August 2012 –July 2014). Total concentration, seasonal variations and intradiurnal periodicities of fungal spores were estimated. Spearman's rank correlation analysis was performed using various weather parameters. The prevalence of fungal spore allergy was investigated among patients reporting to the Depar tment of Allergy and Asthma, Mediland Diagnostics, Kolkata. A retrospective review of patients was conducted with a standard quest...
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Inhibition of Aeromonas hydrophila-induced intestinal inflammation and mucosal barrier function damage in crucian carp by oral administration of Lactococcus lactis
This study explored the immunomodulatory effect and inhibition effects of the candidate probiotic Lactococcus lactis 16-7, which was isolated from crucian carp, on Aeromonas hydrophila infection in crucian carp. The experimental fish were divided into two groups; one was fed a diet supplemented with L. lactis, while the other was fed the control probiotic-free diet. After feeding for 42 d with the experimental diets, the fish that received the diet supplemented with probiotics exhibited a significantly enhanced serum superoxide dismutase activity, phagocytic activities of innate immune cells, and the expression levels of immune-related genes [interferon-γ (INF-γ), interleukin-1β (IL-1β), interleukin-11 (IL-11), tumour necrosis factor α (TNF-α) and myeloid differentiation factor 88 ...
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from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2xk0k4l
Local specific Immunoglobulin E among patients with nonallergic rhinitis: a systematic review.
CONCLUSION: NAR with positive allergy history suggests presence of nspIgE. These patients warrant further allergology evaluation to confirm localized nasal allergy, as they benefit from allergy therapy such as immunotherapy. PMID: 30219822 [PubMed - as supplied by publisher] (Source: Rhinology)
from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2xrNn7L
Aerial fungal spectrum of Kolkata, India, along with their allergenic impact on the public health: a quantitative and qualitative evaluation
AbstractAirborne fungal spores are well documented to trigger respiratory allergy. The present study provides baseline information on the quantitative and qualitative aspects of aerospores for the first time in a typical urban area of Kolkata metropolis, India. An aeromonitoring was performed by Burkard volumetric 7-day sampler for two consecutive years (August 2012 –July 2014). Total concentration, seasonal variations and intradiurnal periodicities of fungal spores were estimated. Spearman's rank correlation analysis was performed using various weather parameters. The prevalence of fungal spore allergy was investigated among patients reporting to the Depar tment of Allergy and Asthma, Mediland Diagnostics, Kolkata. A retrospective review of patients was conducted with a standard quest...
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Standardized quality metric system for structural brain magnetic resonance images in multi-center neuroimaging study
Abstract
Background
Multi-site neuroimaging offer several benefits and poses tough challenges in the drug development process. Although MRI protocol and clinical guidelines developed to address these challenges recommend the use of good quality images, reliable assessment of image quality is hampered by the several shortcomings of existing techniques.
Methods
Given a test image two feature images are extracted. They are grayscale and contrast feature images. Four binary images are generated by setting four different global thresholds on the feature images. Image quality is predicted by measuring the structural similarity between appropriate pairs of binary images. The lower and upper limits of the quality index are 0 and 1. Quality prediction is based on four quality attributes; luminance contrast, texture, texture contrast and lightness.
Results
Performance evaluation on test data from three multi-site clinical trials show good objective quality evaluation across MRI sequences, levels of distortion and quality attributes. Correlation with subjective evaluation by human observers is ≥ 0.6.
Conclusion
The results are promising for the evaluation of MRI protocols, specifically the standardization of quality index, designed to overcome the challenges encountered in multi-site clinical trials.
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Apparent diffusion coefficient as an effective index for the therapeutic efficiency of brain chemoradiotherapy for brain metastases from lung cancer
Abstract
Background
The potential of apparent diffusion coefficient (ADC) value alteration before and after chemoradiotherapy as a potential monitor for therapeutic efficiency of treatment for brain metastases from lung cancer were discussed.
Method
Thirty lung cancer patients with brain metastases, conventional magnetic resonance imaging (MRI) examination and diffusion weighted imaging (DWI) were performed one week before chemoradiotherapy and after one treatment cycle and two treatment cycles. 43 tumor lesions were divided into effective group and invalid group according to the changes of the tumor size. The differences in ADC values at different time points before and after treatment in each treatment group were analyzed.
Result
The maximum diameter of the tumor was no difference after one treatment cycle, but decreased after two treatment cycles. ADC values significantly increased after both one and two treatment cycles. In effective group, the ADC values were significantly increased after one and two treatment cycles. While, there are no difference in invalid group after one treatment cycle but decreased after two treatment cycles. ΔADC values in effective group after one and two treatment cycles were both significantly higher than those in the invalid group. ROC curve analysis then revealed that the area under the curve (AUC) of ΔADC after one treatment was 0.872.
Conclusion
ADC values in brain metastases from lung cancer can help monitor and dynamically observe the therapeutic efficiency of whole brain chemoradiotherapy.
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Standardized quality metric system for structural brain magnetic resonance images in multi-center neuroimaging study
Abstract
Background
Multi-site neuroimaging offer several benefits and poses tough challenges in the drug development process. Although MRI protocol and clinical guidelines developed to address these challenges recommend the use of good quality images, reliable assessment of image quality is hampered by the several shortcomings of existing techniques.
Methods
Given a test image two feature images are extracted. They are grayscale and contrast feature images. Four binary images are generated by setting four different global thresholds on the feature images. Image quality is predicted by measuring the structural similarity between appropriate pairs of binary images. The lower and upper limits of the quality index are 0 and 1. Quality prediction is based on four quality attributes; luminance contrast, texture, texture contrast and lightness.
Results
Performance evaluation on test data from three multi-site clinical trials show good objective quality evaluation across MRI sequences, levels of distortion and quality attributes. Correlation with subjective evaluation by human observers is ≥ 0.6.
Conclusion
The results are promising for the evaluation of MRI protocols, specifically the standardization of quality index, designed to overcome the challenges encountered in multi-site clinical trials.
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