Evaluation of the vitros hiv combo 4th generation test for the identification of hiv infections

Antibody detection against Human Immunodeficiency Virus (HIV) is a commonly-used method for screening HIV infection. Over time, with the improvement of immunological techniques, several generations of tests for detection of anti-HIV antibodies have been developed. The first generation tests, which used an HIV lysate as the source of antigens for the test preparation, had some specificity problems that were minimized in second generation tests which used recombinant antigens (eg in Escherichia coli). (Source: Journal of Clinical Virology)

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