Controversies in Drug Allergy: Beta-Lactam Hypersensitivity Testing

Publication date: Available online 20 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Maria J. Torres, N. Franklin Adkinson, Jean-Christoph Caubet, David A. Khan, Mona I. Kidon, Louis Mendelson, Eva Rebelo Gomes, Ticha Rerkpattanapipat, Shuchen Zhang, Eric Macy, AAAAI/WAO 2018 Symposium Penicillin and Cephalosporin Allergy Testing Working GroupAll beta-lactam use is associated with a certain rate of adverse reactions. Many of these adverse reactions result in an allergy to the beta-lactam being entered into the patient's medical record. Unfortunately, only a small minority of these recorded allergies are clinically significant immunologically mediated drug hypersensitivity. An unconfirmed allergy to beta-lactams is a significant public health ris...

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