Publication date: Available online 10 September 2018Source: Veterinary Immunology and ImmunopathologyAuthor(s): Racheal Aye, Yenehiwot Berhanu Weldearegay, Harrison Osundwa Lutta, Francis Chuma, Andreas Pich, Joerg Jores, Jochen Meens, Jan NaessensAbstractMycoplasma mycoides subspecies mycoides (Mmm) adhesion is tissue and host specific. Inhibition of adhesion will prevent Mmm from binding to lung cells and hence prevent colonization and disease. The aim of this study was to develop a panel of Mmm monoclonal antibodies against Mmm and use these antibodies to investigate their inhibitory effect on the adherence of Mmm to bovine lung epithelial cells (BoLEC), and to further identify an antigen to any of the inhibitory antibodies. Thirteen anti-Mycoplasma mycoides subsp. mycoides (AMMY) monoc...
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