Independent and simultaneous effect of crustacean hyperglycemic hormone and dopamine on the hemocyte intracellular signaling pathways and immune responses in white shrimp Litopenaeus vannamei

Publication date: Available online 12 September 2018Source: Fish & Shellfish ImmunologyAuthor(s): Lan Zhang, Luqing Pan, Lijun Xu, Lingjun SiAbstractImmune responses and intracellular signaling pathways were examined after hemolymph of Litopenaeus vannamei being incubated in Crustacean hyperglycemic hormone (CHH), dopamine (DA) and DA antagonist (Y). The results showed that the effect CHH and CHH + DA + Y on viability of hemocytes were no significant changes compared to the control group. However, in DA, DA + Y and CHH + DA groups, the viability of hemocytes decreased significantly. The phagocytic activity and the antibacterial activity of CHH group were increased significantly within 12h. Whereas the CHH + DA, DA were significantly lower than the control. PO in haemolymph was up...

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