Using CT texture analysis to differentiate between nasopharyngeal cancer and age-matched adenoid controls

Publication date: Available online 24 September 2018

Source: European Journal of Radiology

Author(s): Amy Tsai, Karen Buch, Akifumi Fujita, Muhammad Mustafa Qureshi, Hirofumi Kuno, Margaret N. Chapman, Baojun Li, Masafumi Oda, Minh Tam Truong, Osamu Sakai

ABSTRACT

OBJECTIVES

To investigate the use of texture analysis to quantitatively distinguish nasopharyngeal carcinoma (NPC) from normal adenoid on CT.

METHODS

In this IRB-approved, retrospective study, nasopharyngeal tissues in 13 patients with NPC and 13 control patients were manually contoured, segmented, and imported to an in-house developed texture analysis program, which extracted 41 texture features. Basic descriptive statistics were performed to evaluate for differences in texture parameters between NPC and controls.

RESULTS

Statistically significant differences between NPC and controls were seen in 32 of 41 texture features. These significant differences were present in 11 of 12 histogram features, 4 of 5 gray-level co-occurrence matrix features, 7 of 11 gray-level run length features, 4 of 4 gray-level gradient matrix features, and 6 of 9 Laws features.

CONCLUSION

Significant differences in many texture features were seen between NPC and normal adenoids. CT texture analysis may aid in differentiating NPC from normal adenoid tissue.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2OOSy9j