Association of Malassezia to Atopic Dermatitis

AbstractPurpose of ReviewAtopic dermatitis (AD) is a common chronic, inherited, relapsing, inflammatory skin condition. A multifactorial etiology has been postulated, including genetic and immunological factors, impaired skin barrier function and environmental triggers, all of them are relevant in the pathogenesis.Malassezia spp. is the most common fungi of the skin microbiome. Most of the studies comparing the skin colonization withMalassezia spp. in healthy people and AD patients did not show difference between both groups. This review aims to show the studies carried out in this regard and the reported evidence about the role ofMalassezia spp. in the pathogenesis of AD.Recent FindingsThe rate of IgE-mediated sensitizationMalassezia spp. is very high in AD patients, mainly in adult patie...

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