Commentary: Propofol Versus Remifentanil: Which One Is More Effective in Reducing Blood Loss During Orthognathic Surgery? A Randomized Clinical Trial

We recently read the article by Eshghpour et al., "Propofol versus Remifentanil: Which One is More Effective in Reducing Blood Loss During Orthognathic Surgery? A Randomized Clinical Trial."1 As a center that performs a high volume of orthognathic surgical procedures annually, we were very interested in this work as it purports to present high-level evidence for minimizing blood loss during these operations. However, upon critically evaluating the work, we identified several issues that may preclude acceptance of the authors' stated conclusions.

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