Legionella feeleii : pneumonia or Pontiac fever? Bacterial virulence traits and host immune response

AbstractGram-negative bacteriumLegionella is able to proliferate intracellularly in mammalian host cells and amoeba, which became known in 1976 since they caused a large outbreak of pneumonia. It had been reported that different strains ofLegionella pneumophila, Legionella micdadei, Legionella longbeachae, andLegionella feeleii caused human respiratory diseases, which were known as Pontiac fever or Legionnaires ' disease. However, the differences of the virulence traits among the strains of the single species and the pathogenesis of the two diseases that were due to the bacterial virulence factors had not been well elucidated.L. feeleii is an important pathogenic organism in Legionellae, which attracted attention due to cause an outbreak of Pontiac fever in 1981 in Canada. In published r...

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