Diagnostic utility of microsurgical carbon-dioxide laser excision of oral potentially malignant lesions (OPMLs) vs incisional biopsy: a retrospective histopathological review

Complete excision of oral potentially malignant lesions (OPMLs) could result in improved and earlier detection of more severe grades of oral epithelial dysplasia and/or frank malignancy. Transoral micro-surgical carbon dioxide (CO2) laser techniques allow for resection of OPMLs, even those that are extensive. The advantages are improved diagnostic yield, improved viability of the specimen for pathologic evaluation reduced post-surgical morbidity and easier post-operative clinical surveillance.

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