TroCCL4, a CC chemokine of Trachinotus ovatus, is involved in the antimicrobial immune response

Publication date: March 2019Source: Fish & Shellfish Immunology, Volume 86Author(s): Baiming Sun, Yang Lei, Zhenjie Cao, Yongcan Zhou, Yun Sun, Ying Wu, Shifeng Wang, Weiliang Guo, Chunsheng LiuAbstractCC chemokines are a large subfamily of chemokines that play an important role in the innate immune system. To date, several CC chemokines have been identified in fish species; however, the activities and functions of these putative chemokines remain ambiguous in teleosts, especially in the golden pompano, Trachinotus ovatus. Here, we characterized CC chemokine ligand 4 from T. ovatus (TroCCL4) and studied its functions. TroCCL4 contains a 294 bp open reading frame that encodes a putative peptide comprising 97 amino acids. TroCCL4 shares a high amino acid sequence similarity of 31.11%–78.35...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2E6C0XL