NCCIH Integrative Medicine Research Lecture The characterization of biologically active small molecules (natural products) produced by easily cultured bacteria has been a rewarding avenue for identifying novel therapeutics. The characterization of biologically active small molecules (natural products) produced by easily cultured bacteria has been a rewarding avenue for identifying novel therapeutics, as well as gaining insights into how bacteria interact with the world around them. Large-scale sequencing of bacterial genomic and metagenomic DNA indicates that the traditional pure culture – based approach to studying bacterial natural products has provided access only to a small fraction of the diverse metabolites encoded by environmental microbiomes. In particular, these studies suggest ...
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