Authors: Kim DH Abstract Neonates, especially extremely low-birth-weight infants are one of the most heavily transfused groups among all patients. Because they are exposed to higher specific risks of transfusion compared to other age groups, many special considerations are required for transfusion therapy in neonates. The risks of transfusion in neonates include adverse outcomes specific for preterm infants as well as increased metabolic, immunologic, and infectious complications. To reduce the risks of transfusion-transmitted cytomegalovirus infection and transfusion-associated graft versus host, leukoreduced and irradiated cellular blood products should be used for all neonates. This review summarizes the risks of neonatal transfusion therapy and specific methods to reduce them. ...
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